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Metabolic Brain Disease

Erschienen in:

01.09.2014 | Review Article

Resting-state functional magnetic resonance imaging in hepatic encephalopathy: current status and perspectives

verfasst von: Long Jiang Zhang, Shengyong Wu, Jiaqian Ren, Guang Ming Lu

Erschienen in: Metabolic Brain Disease | Ausgabe 3/2014

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Abstract

Hepatic encephalopathy (HE) is a neuropsychiatric syndrome which develops in patients with severe liver diseases and/or portal-systemic shunting. Minimal HE, the earliest manifestation of HE, has drawn increasing attention in the last decade. Minimal HE is associated with a series of brain functional changes, such as attention, working memory, and so on. Blood oxygen level dependent (BOLD) functional MRI (fMRI), especially resting-state fMRI has been used to explore the brain functional changes of HE, yielding important insights for understanding pathophysiological mechanisms and functional reorganization of HE. This paper briefly reviews the principles of BOLD fMRI, potential applications of resting-state fMRI with advanced post-processing algorithms such as regional homogeneity, amplitude of low frequency fluctuation, functional connectivity and future research perspective in this field.

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Titel: Resting-state functional magnetic resonance imaging in hepatic encephalopathy: current status and perspectives
verfasst von: Long Jiang Zhang
Shengyong Wu
Jiaqian Ren
Guang Ming Lu
Publikationsdatum: 01.09.2014
Verlag: Springer US
Erschienen in: Metabolic Brain Disease / Ausgabe 3/2014
Print ISSN: 0885-7490
Elektronische ISSN: 1573-7365
DOI: https://doi.org/10.1007/s11011-014-9504-9

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Resting-state functional magnetic resonance imaging in hepatic encephalopathy: current status and perspectives

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