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Metabolic Brain Disease

Metabolic Brain Disease OnlineFirst articles

27.02.2020 | Original Article

Toxicity of ayahuasca after 28 days daily exposure and effects on monoamines and brain-derived neurotrophic factor (BDNF) in brain of Wistar rats

Ayahuasca is a hallucinogenic beverage that affects the serotonergic system and have therapeutic potential for many diseases and disorders, including depression and drug addiction. The objectives of this study were to evaluate the potential toxic …

21.02.2020 | Original Article

Neuroprotective effects of miR-532-5p against ischemic stroke

Stroke can cause death and disability and has a high incidence with many complications. So far, effective treatment options for stroke are still limited. MicroRNA-532-5p (miR-532-5p) is significantly downregulated in stroke. However, the role of …

17.02.2020 | Original Article

Vanillin and vanillic acid modulate antioxidant defense system via amelioration of metabolic complications linked to Fe2+-induced brain tissues damage

The therapeutic effect of phenolics on neurodegenerative diseases has been attributed to their potent antioxidant properties. In the present study, the neuroprotective activities of vanillin and vanillic acid were investigated in Fe2+- induced …

15.02.2020 | Original Article

Grafted human chorionic stem cells restore motor function and preclude cerebellar neurodegeneration in rat model of cerebellar ataxia

Cerebellar ataxia (CA) is a form of ataxia that adversely affects the cerebellum. Cell replacement therapy (CRT) has been considered as a potential treatment for neurological disorders. In this report, we investigated the neuro-restorative effects …

12.02.2020 | Original Article

Amnesia-ameliorative effect of a quinoline derivative through regulation of oxidative/cholinergic systems and Na+/K+-ATPase activity in mice

The present study evaluated the anti-amnesic activity of 1-(7-chloroquinolin-4-yl)-5-methyl-N-phenyl-1H-1,2,3-triazole-4-carboxamide (QTCA-1) against scopolamine (SCO)-induced amnesia in mice. It was evaluated cholinergic dysfunction, oxidative …

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Über diese Zeitschrift

Metabolic Brain Disease serves as a forum for the publication of outstanding basic and clinical papers on brain diseases, including both human and animal studies. Topics include, but are not limited to, stroke, traumatic brain injury, myelin disorders, epilepsy, multiple sclerosis, toxic encephalopathies, genetic diseases affecting the brain, alcohol and brain metabolism, neuroendocrinopathies, viral and nonviral encephalitides, nutritional disorders affecting the brain, diseases affecting neurotransmitters, Alzheimer's disease, Parkinson’s disease, amyotrophic lateral sclerosis and aging. The journal publishes papers on the fundamental pathogenesis of these disorders and on related experimental and clinical techniques and methodologies. Metabolic Brain Disease is directed to neuroscientists, psychiatrists, neurologists, pathologists, and others involved in the research and treatment of a broad range of brain disorders.

Metabolic Brain Disease will consider Full Research Papers, Short Communications, Review Articles and Editorials. The journal is committed to high standards of presentation. Please contact the Editor to discuss the suitability of topics.

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