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01.12.2012 | Case Report

Right- and left-sided carcinoid heart disease without intracardiac shunting

verfasst von: Go Igawa, Katsunori Ishida, Koichi Matsubara, Yoshiharu Kinugasa, Kazuyoshi Ogura, Masahiko Kato, Kazuhiro Yamamoto

Erschienen in: Journal of Echocardiography | Ausgabe 4/2012

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Abstract

We present a case of a 54-year-old man with carcinoid heart disease and mitral valve involvement. He had hepatic carcinoid with an extremely elevated urinary excretion of 5-hydroxyindole acetic acid and was referred to our division for shortness of breath and leg edema. Transthoracic echocardiography showed the thickened and retracted tricuspid valve leaflets and severe tricuspid regurgitation. Moderate mitral regurgitation was observed, with the involvement of mitral valve leaflets. A patent foramen ovale was not detected on transesophageal echocardiography. The extremely high concentration of circulating serotonin and/or other vasoactive substances may have contributed to left- as well as right-sided carcinoid heart disease.

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Møller JE, Connolly HM, Rubin J, et al. Factors associated with progression of carcinoid heart disease. N Engl J Med. 2003;348:1005–15.PubMedCrossRef

Robiolio PA, Rigolin VH, Wilson JS, et al. Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography. Circulation. 1995;92:790–5.PubMedCrossRef

Bhattacharyya S, Toumpanakis C, Caplin ME, et al. Analysis of 150 patients with carcinoid syndrome seen in a single year at one institution in the first decade of the twenty-first century. Am J Cardiol. 2008;101:378–81.PubMedCrossRef

Connolly HM, Schaff HV, Mullany CJ, et al. Surgical management of left-sided carcinoid heart disease. Circulation. 2001;104:I36–40.PubMedCrossRef

Titel: Right- and left-sided carcinoid heart disease without intracardiac shunting
verfasst von: Go Igawa
Katsunori Ishida
Koichi Matsubara
Yoshiharu Kinugasa
Kazuyoshi Ogura
Masahiko Kato
Kazuhiro Yamamoto
Publikationsdatum: 01.12.2012
Verlag: Springer Japan
Erschienen in: Journal of Echocardiography / Ausgabe 4/2012
Print ISSN: 1349-0222
Elektronische ISSN: 1880-344X
DOI: https://doi.org/10.1007/s12574-012-0138-9

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Right- and left-sided carcinoid heart disease without intracardiac shunting

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