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Cardiovascular Drugs and Therapy
Erschienen in: Cardiovascular Drugs and Therapy 1/2019

25.01.2019 | REVIEW ARTICLE

Risk Assessment of Stroke in Patients with Atrial Fibrillation: Current Shortcomings and Future Directions

verfasst von: Daniel A. Hyman, Vincent Siebert, Xiaoming Jia, Mahboob Alam, Glenn N. Levine, Salim S. Virani, Yochai Birnbaum

Erschienen in: Cardiovascular Drugs and Therapy | Ausgabe 1/2019

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Abstract

Atrial fibrillation is a well-known risk factor for cardioembolic stroke; a number of risk stratification scoring systems have been developed to help differentiate which patients would stand to benefit from anticoagulation. However, these scoring systems cannot be utilized in patients whose atrial fibrillation has not been diagnosed. As implantable cardiac monitors become more prevalent, it becomes possible to identify occult, subclinical atrial fibrillation. With this data, it is also possible to examine the relationship between episodes of paroxysmal atrial fibrillation and thromboembolism and the total burden of paroxysmal atrial fibrillation and thromboembolic risk. The data gleaned from these devices provides insight and raises questions regarding the underlying mechanism of thromboembolism in atrial fibrillation, and in doing so, exposes shortcomings in the present clinical use of current risk scoring systems, specifically, the inability to account for atrial fibrillation burden and to apply scores at all in subclinical atrial fibrillation.
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Metadaten
Titel
Risk Assessment of Stroke in Patients with Atrial Fibrillation: Current Shortcomings and Future Directions
verfasst von
Daniel A. Hyman
Vincent Siebert
Xiaoming Jia
Mahboob Alam
Glenn N. Levine
Salim S. Virani
Yochai Birnbaum
Publikationsdatum
25.01.2019
Verlag
Springer US
Erschienen in
Cardiovascular Drugs and Therapy / Ausgabe 1/2019
Print ISSN: 0920-3206
Elektronische ISSN: 1573-7241
DOI
https://doi.org/10.1007/s10557-018-06849-7

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