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Supportive Care in Cancer
Erschienen in: Supportive Care in Cancer 12/2023

01.12.2023 | Research

Risk factors for malnutrition in patients with nasopharyngeal carcinoma

verfasst von: Pengpeng Wang, Kim Lam Soh, Yanping Ying, Jinlian Liao, Xueling Huang, Huihan Zhao, Xiao Pan, Lan Deng, Xiaoxia Yu

Erschienen in: Supportive Care in Cancer | Ausgabe 12/2023

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Abstract

Background

Malnutrition is a common complication in patients with nasopharyngeal carcinoma (NPC). However, there are few studies on risk factors for malnutrition in NPC patients. Our aims were to identify the risk factors for malnutrition in NPC patients.

Methods

NPC patients were recruited in this cross-sectional study, and they were divided into well-nourished and malnourished groups according to the Global Leadership Initiative on Malnutrition (GLIM). Potential risk factors were initially screened using univariate analysis (p < 0.1), and the selected ones were analyzed by logistic regression analysis (p < 0.05) to identify the risk factors for malnutrition in NPC patients.

Results

In total, 305 NPC patients meeting eligibility criteria were enrolled. Multivariate logistic regression analysis revealed that low body mass index (BMI) (OR = 0.596, 95% CI 0.520–0.683, p < 0.001), the high total radiation dose received (OR = 1.046, 95% CI 1.023–1.069, p < 0.001), appetite loss (OR = 2.839, 95% CI 1.269–6.353, p = 0.011), and low PA (OR = 0.993, 95% CI 0.988–0.998, p = 0.008) were risk factors for malnutrition in NPC patients.

Conclusions

The low BMI, the high total radiation dose received, appetite loss, and low prealbumin were risk factors for malnutrition in NPC patients.
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Metadaten
Titel
Risk factors for malnutrition in patients with nasopharyngeal carcinoma
verfasst von
Pengpeng Wang
Kim Lam Soh
Yanping Ying
Jinlian Liao
Xueling Huang
Huihan Zhao
Xiao Pan
Lan Deng
Xiaoxia Yu
Publikationsdatum
01.12.2023
Verlag
Springer Berlin Heidelberg
Erschienen in
Supportive Care in Cancer / Ausgabe 12/2023
Print ISSN: 0941-4355
Elektronische ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-023-08166-8

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