Skip to main content
Erschienen in: International Ophthalmology 1/2019

26.12.2017 | Original Paper

Role of trabeculectomy in advanced glaucoma: Whether we stand to consider it a bane or a boon today?

verfasst von: Harinder Singh Sethi, Mayuresh P. Naik, Komal Saluja

Erschienen in: International Ophthalmology | Ausgabe 1/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To elucidate the role of trabeculectomy in advanced glaucoma.

Materials and methods

Only patients with primary open-angle glaucoma were selected. All patients who had cup–disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Target IOP was defined as ≤ 12 mm Hg. Patients who showed progression were included in the study. A total of 10 patients were selected. Trabeculectomy was performed using limbal-based conjunctival flap. Patients were followed up for a period of 2 years for visual acuity, intraocular pressure, visual fields, slit-lamp biomicroscopy and bleb morphology.

Results

Mean preoperative intraocular pressure on five drugs was 21.7 ± 3.8 mm Hg (range 18–27 mm Hg) on maximum medical therapy. Mean post-operative intraocular pressure was 11 ± 1.78 mm Hg (range 9–13 mm Hg) and 11 ± 1.92 mm Hg (range 9–14 mm Hg) at 1 month and 6 months post-operatively, respectively. Post-operatively, the visual acuity remained stable in 17 patients. It dropped by 1 Snellen line in 2 patients and 2 Snellen lines in 1 patient, respectively, over a period of 6 months and later improved to 6/6P following cataract surgery. There was no defined visual field progression in any of the 20 patients.

Conclusion

Besides being a cost-effective alternative to medical management, trabeculectomy not only provides a better IOP control but also has a high safety profile when performed by an experienced surgeon.
Literatur
1.
Zurück zum Zitat George R, Ve RS, Vijaya L (2010) Glaucoma in India: estimated burden of disease. J Glaucoma 19(6):391–397CrossRefPubMed George R, Ve RS, Vijaya L (2010) Glaucoma in India: estimated burden of disease. J Glaucoma 19(6):391–397CrossRefPubMed
3.
Zurück zum Zitat VanVeldhuisen Paul C, Ederer F et al (2000) The advanced glaucoma intervention study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol 130:429–440CrossRef VanVeldhuisen Paul C, Ederer F et al (2000) The advanced glaucoma intervention study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol 130:429–440CrossRef
4.
Zurück zum Zitat Caprioli J, Coleman AL (2008) Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study. Ophthalmology 115(1123–1129):e3 Caprioli J, Coleman AL (2008) Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study. Ophthalmology 115(1123–1129):e3
5.
Zurück zum Zitat National Institute for Health and Clinical Excellence (NICE) (2009) Glaucoma: diagnosis and management of chronic open angle glaucoma and ocular hypertension. Clinical Guidelines CG85, UK National Institute for Health and Clinical Excellence (NICE) guidelines. Developed by the National Collaborating Centre for Acute Care National Institute for Health and Clinical Excellence (NICE) (2009) Glaucoma: diagnosis and management of chronic open angle glaucoma and ocular hypertension. Clinical Guidelines CG85, UK National Institute for Health and Clinical Excellence (NICE) guidelines. Developed by the National Collaborating Centre for Acute Care
6.
Zurück zum Zitat Landers J, Martin K, Sarkies N et al (2012) A 20-year follow-up study of trabeculectomy: risk factors and outcomes. Ophthalmology 119(4):694–702CrossRefPubMed Landers J, Martin K, Sarkies N et al (2012) A 20-year follow-up study of trabeculectomy: risk factors and outcomes. Ophthalmology 119(4):694–702CrossRefPubMed
7.
Zurück zum Zitat Quigely HA, Borman AT (2006) The number of the people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267CrossRef Quigely HA, Borman AT (2006) The number of the people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267CrossRef
8.
Zurück zum Zitat Grant WM, Burke JF (1982) Why do some people go blind from glaucoma? Ophthalmology 89:991–998CrossRefPubMed Grant WM, Burke JF (1982) Why do some people go blind from glaucoma? Ophthalmology 89:991–998CrossRefPubMed
9.
Zurück zum Zitat Ramakrishnan R, Nirmalan PK, Krishandas R et al (2003) Glaucoma in a rural population of southern India: the Aravind comprehensive eye survey. Ophthalmology 110:1484–1490CrossRefPubMed Ramakrishnan R, Nirmalan PK, Krishandas R et al (2003) Glaucoma in a rural population of southern India: the Aravind comprehensive eye survey. Ophthalmology 110:1484–1490CrossRefPubMed
10.
Zurück zum Zitat Hodapp E, Parrish RK II, Anderson DR (1993) Clinical decisions in glaucoma. Mosby, St. Louis Hodapp E, Parrish RK II, Anderson DR (1993) Clinical decisions in glaucoma. Mosby, St. Louis
11.
Zurück zum Zitat Jones E, Clarke J, Khaw PT (2005) Recent advances in trabeculectomy technique. Curr Opin Ophthalmol 16:107–113CrossRefPubMed Jones E, Clarke J, Khaw PT (2005) Recent advances in trabeculectomy technique. Curr Opin Ophthalmol 16:107–113CrossRefPubMed
12.
Zurück zum Zitat Francis BA, Singh K, Lin SC et al (2011) Novel glaucoma procedures: a report by the American Academy of Ophthalmology. Ophthalmology 118(7):1466–1480CrossRefPubMed Francis BA, Singh K, Lin SC et al (2011) Novel glaucoma procedures: a report by the American Academy of Ophthalmology. Ophthalmology 118(7):1466–1480CrossRefPubMed
13.
Zurück zum Zitat Souza C, Tran DH, Loman J, Law SK, Coleman AL, Caprioli J (2007) Long-term outcomes of Ahmed glaucoma valve implantation in refractory glaucomas. Am J Ophthalmol 144:893–900CrossRefPubMed Souza C, Tran DH, Loman J, Law SK, Coleman AL, Caprioli J (2007) Long-term outcomes of Ahmed glaucoma valve implantation in refractory glaucomas. Am J Ophthalmol 144:893–900CrossRefPubMed
15.
Zurück zum Zitat Moster MR, Moster ML (2005) Wipe-out: a complication of glaucoma surgery or just a blast from the past? Am J Ophthalmol 140:705–706CrossRefPubMed Moster MR, Moster ML (2005) Wipe-out: a complication of glaucoma surgery or just a blast from the past? Am J Ophthalmol 140:705–706CrossRefPubMed
Metadaten
Titel
Role of trabeculectomy in advanced glaucoma: Whether we stand to consider it a bane or a boon today?
verfasst von
Harinder Singh Sethi
Mayuresh P. Naik
Komal Saluja
Publikationsdatum
26.12.2017
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 1/2019
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-017-0797-7

Weitere Artikel der Ausgabe 1/2019

International Ophthalmology 1/2019 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Ophthalmika in der Schwangerschaft

Die Verwendung von Ophthalmika in der Schwangerschaft und Stillzeit stellt immer eine Off-label-Anwendung dar. Ein Einsatz von Arzneimitteln muss daher besonders sorgfältig auf sein Risiko-Nutzen-Verhältnis bewertet werden. In der vorliegenden …

Operative Therapie und Keimnachweis bei endogener Endophthalmitis

Vitrektomie Originalie

Die endogene Endophthalmitis ist eine hämatogen fortgeleitete, bakterielle oder fungale Infektion, die über choroidale oder retinale Gefäße in den Augapfel eingeschwemmt wird [ 1 – 3 ]. Von dort infiltrieren die Keime in die Netzhaut, den …

Bakterielle endogene Endophthalmitis

Vitrektomie Leitthema

Eine endogene Endophthalmitis stellt einen ophthalmologischen Notfall dar, der umgehender Diagnostik und Therapie bedarf. Es sollte mit geeigneten Methoden, wie beispielsweise dem Freiburger Endophthalmitis-Set, ein Keimnachweis erfolgen. Bei der …

So erreichen Sie eine bestmögliche Wundheilung der Kornea

Die bestmögliche Wundheilung der Kornea, insbesondere ohne die Ausbildung von lichtstreuenden Narben, ist oberstes Gebot, um einer dauerhaften Schädigung der Hornhaut frühzeitig entgegenzuwirken und die Funktion des Auges zu erhalten.   

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.