Skip to main content
Erschienen in: The journal of nutrition, health & aging 8/2019

24.06.2019

SARC-F Validation and SARC-F+EBM Derivation in Musculoskeletal Disease: The SPSS-OK Study

verfasst von: Noriaki Kurita, T. Wakita, T. Kamitani, O. Wada, K. Mizuno

Erschienen in: The journal of nutrition, health & aging | Ausgabe 8/2019

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To validate the SARC-F questionnaire for sarcopenia screening in musculoskeletal disease setting, and to assess improvements in diagnostic accuracy by adding “EBM” (elderly and body mass index information) to the SARC-F.

Design

Diagnostic accuracy study.

Setting and Participants

The center involved in this study was located in an urban area of Kobe City, Japan. People with musculoskeletal disease in the knee, hip, or spine who were scheduled for surgical treatment were included.

Measurements

Sarcopenia was evaluated using the Asian Working Group for Sarcopenia (AWGS) and the European Working Group on Sarcopenia in Older People (EWGSOP2), which included bioimpedance, handgrip strength, and gait speed. Patients answered the SARC-F questionnaire and their body mass index was measured. SARC-F and “EBM” information were combined into an original score. The sensitivities, specificities, and areas under the receiver operating characteristic curve (AUC) were estimated and compared to identify sarcopenia.

Results

A total of 959 patients were included. Sarcopenia by AWGS criteria was identified in 36 (3.8%) patients. SARC-F had a sensitivity of 41.7% and specificity of 68.5%. SARC-F+EBM had a sensitivity of 77.8% and specificity of 69.6%, with substantial improvement in sensitivity (P<0.001). The AUCs for SARC-F and SARC-F+EBM were 0.557 (95% confidence interval [CI] 0.452–0.662) and 0.824 (95% CI 0.762–0.886), respectively (P<0.001). Similar results were obtained when EWGSOP2 criteria were used as the reference standard.

Conclusion

The SARC-F alone is not adequate for finding cases in musculoskeletal disease settings. SARC-F+EBM significantly improved the sensitivity and overall diagnostic accuracy of the SARC-F for screening sarcopenia. SARC-F+EBM is potentially useful for screening sarcopenia in different ethnic and disease settings.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
3.
Zurück zum Zitat Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M. Sarcopenia: revised European consensus on definition and diagnosis. Age and ageing 2019;48(1):16–31. doi:https://doi.org/10.1093/ageing/afy169 CrossRef Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M. Sarcopenia: revised European consensus on definition and diagnosis. Age and ageing 2019;48(1):16–31. doi:https://​doi.​org/​10.​1093/​ageing/​afy169 CrossRef
7.
Zurück zum Zitat Landi F, Cruz-Jentoft AJ, Liperoti R, Russo A, Giovannini S, Tosato M, Capoluongo E, Bernabei R, Onder G. Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study. Age and ageing 2013;42(2):203–209CrossRef Landi F, Cruz-Jentoft AJ, Liperoti R, Russo A, Giovannini S, Tosato M, Capoluongo E, Bernabei R, Onder G. Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study. Age and ageing 2013;42(2):203–209CrossRef
8.
Zurück zum Zitat Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Capoluongo E, Bernabei R, Onder G. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clin Nutr 2012;31(5):652–658CrossRef Landi F, Liperoti R, Russo A, Giovannini S, Tosato M, Capoluongo E, Bernabei R, Onder G. Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study. Clin Nutr 2012;31(5):652–658CrossRef
9.
Zurück zum Zitat Kemmler W, Teschler M, Goisser S, Bebenek M, von Stengel S, Bollheimer LC, Sieber CC, Freiberger E. Prevalence of sarcopenia in Germany and the corresponding effect of osteoarthritis in females 70 years and older living in the community: results of the FORMoSA study. Clin Interv Aging 2015;10:1565–1573. doi:https://doi.org/10.2147/CIA.S89585 CrossRef Kemmler W, Teschler M, Goisser S, Bebenek M, von Stengel S, Bollheimer LC, Sieber CC, Freiberger E. Prevalence of sarcopenia in Germany and the corresponding effect of osteoarthritis in females 70 years and older living in the community: results of the FORMoSA study. Clin Interv Aging 2015;10:1565–1573. doi:https://​doi.​org/​10.​2147/​CIA.​S89585 CrossRef
10.
Zurück zum Zitat Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, Chou MY, Chen LY, Hsu PS, Krairit O, Lee JS, Lee WJ, Lee Y, Liang CK, Limpawattana P, Lin CS, Peng LN, Satake S, Suzuki T, Won CW, Wu CH, Wu SN, Zhang T, Zeng P, Akishita M, Arai H. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. Journal of the American Medical Directors Association 2014;15(2):95–101. doi:https://doi.org/10.1016/j.jamda.2013.11.025 CrossRef Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, Chou MY, Chen LY, Hsu PS, Krairit O, Lee JS, Lee WJ, Lee Y, Liang CK, Limpawattana P, Lin CS, Peng LN, Satake S, Suzuki T, Won CW, Wu CH, Wu SN, Zhang T, Zeng P, Akishita M, Arai H. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. Journal of the American Medical Directors Association 2014;15(2):95–101. doi:https://​doi.​org/​10.​1016/​j.​jamda.​2013.​11.​025 CrossRef
13.
Zurück zum Zitat Ouchi Y, Rakugi H, Arai H, Akishita M, Ito H, Toba K, Kai I, Society obotJCoJG, definition JGSot, elderly cot. Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society. Geriatrics &amp; gerontology international 2017;17(7):1045–1047. doi:doi:https://doi.org/10.1111/ggi.13118 CrossRef Ouchi Y, Rakugi H, Arai H, Akishita M, Ito H, Toba K, Kai I, Society obotJCoJG, definition JGSot, elderly cot. Redefining the elderly as aged 75 years and older: Proposal from the Joint Committee of Japan Gerontological Society and the Japan Geriatrics Society. Geriatrics &amp; gerontology international 2017;17(7):1045–1047. doi:doi:https://​doi.​org/​10.​1111/​ggi.​13118 CrossRef
15.
18.
Zurück zum Zitat Liu X. Classification accuracy and cut point selection. Statistics in medicine 2012;31(23):2676–2686CrossRef Liu X. Classification accuracy and cut point selection. Statistics in medicine 2012;31(23):2676–2686CrossRef
22.
Metadaten
Titel
SARC-F Validation and SARC-F+EBM Derivation in Musculoskeletal Disease: The SPSS-OK Study
verfasst von
Noriaki Kurita
T. Wakita
T. Kamitani
O. Wada
K. Mizuno
Publikationsdatum
24.06.2019
Verlag
Springer Paris
Erschienen in
The journal of nutrition, health & aging / Ausgabe 8/2019
Print ISSN: 1279-7707
Elektronische ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1222-x

Weitere Artikel der Ausgabe 8/2019

The journal of nutrition, health & aging 8/2019 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.