Erschienen in:
25.01.2020 | SARS-CoV-2 | Brief Report
A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus
verfasst von:
Yan Wang, Xuejiao Cui, Xu Chen, Shixing Yang, Yu Ling, Qianben Song, Su Zhu, Luying Sun, Chuang Li, Yu Li, Xutao Deng, Eric Delwart, Wen Zhang
Erschienen in:
Archives of Virology
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Ausgabe 3/2020
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Abstract
Using viral metagenomics, the complete genome sequence of an infectious bronchitis virus (IBV) strain (named ahysx-1) from a fecal sample from a healthy chicken in Anhui province, China, was determined. The genome sequence of ahysx-1 was found to be very similar to that of IBV strain ck/CH/LLN/131040 (KX252787), except for the spike gene region, which is similar to that of a turkey coronavirus strain (EU022526), suggesting that ahysx-1 is a recombinant. Recombination analysis and phylogenetic analysis based on the genomic sequences of ahysx-1 and other related strains confirmed that ahysx-1 appears to be a recombinant resulting from a recombination event that occurred between a chicken coronavirus and a turkey coronavirus. Further studies need to be performed to determine whether this recombinant IBV strain is pathogenic and whether it is transmitted between chickens and turkeys.