Skip to main content
Erschienen in: Digestive Diseases and Sciences 2/2020

18.05.2019 | Original Article

Self-Expandable Metallic Stent Is More Cost Efficient Than Plastic Stent in Treating Anastomotic Biliary Stricture

verfasst von: Sunguk Jang, Tyler Stevens, Rocio Lopez, Prabhleen Chahal, Amit Bhatt, Madhu Sanaka, John J. Vargo

Erschienen in: Digestive Diseases and Sciences | Ausgabe 2/2020

Einloggen, um Zugang zu erhalten

Abstract

Background

Anastomotic bile duct stricture (ABS) is one of the most common complications after liver transplantation. Current practice of endoscopic retrograde cholangiopancreatography (ERCP) with multiple plastic stent (MPS) insertion often requires multiple sessions before achieving stricture resolution. We aimed to compare the efficacy of fully covered self-expandable metallic stent (FCSEMS) with MPS method while simultaneously analyzing the relative healthcare cost between the two methods in the management of ABS.

Methods

Liver transplant patients with ABS who received ERCP with stent placement were identified by query of our endoscopic database. Comparative analyses between the group of patients treated with ERCP with MPS and the group treated with FCSEMS were performed. The costs to achieve stricture resolution, and the rates of stricture resolution, recurrence and complications were also compared.

Results

A total of 158 patients underwent ERCP with stent insertion for the management of ABS. Of those, 49 patient received FCSEMS for their ABS while 109 patients were treated with MPS only. Our cost analysis showed early utilization of FCSEMS can deliver up to 25% savings in the total procedure cost while providing comparable rates of stricture resolution. The rates of technical success, stricture recurrence and adverse outcomes, and stricture free durations were also comparable between the two groups.

Conclusion

While providing efficacy and safety rates comparable to ERCP-MPS, the incorporation of FCSEMS at early stage of ABS management could provide a substantial savings by reducing the number of ERCP session to achieve stricture resolution. Optimization of the timing and duration of FCSEMS indwelling time needs further validation.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Sharma S, Gurakar A, Jabbour N. Biliary strictures following liver transplantation: past, present and preventive strategies. Liver Transpl. 2008;14:759–769.CrossRef Sharma S, Gurakar A, Jabbour N. Biliary strictures following liver transplantation: past, present and preventive strategies. Liver Transpl. 2008;14:759–769.CrossRef
2.
Zurück zum Zitat Verdonk RC, Buis CI, Porte RJ, et al. Anastomotic biliary strictures after liver transplantation: causes and consequences. Liver Transpl. 2006;12:726–735.CrossRef Verdonk RC, Buis CI, Porte RJ, et al. Anastomotic biliary strictures after liver transplantation: causes and consequences. Liver Transpl. 2006;12:726–735.CrossRef
3.
Zurück zum Zitat Welling TH, Heidt DG, Englesbe MJ, et al. Biliary complications following liver transplantation in the model for end-stage liver disease era: effect of donor, recipient, and technical factors. Liver Transpl. 2007;14:73–80.CrossRef Welling TH, Heidt DG, Englesbe MJ, et al. Biliary complications following liver transplantation in the model for end-stage liver disease era: effect of donor, recipient, and technical factors. Liver Transpl. 2007;14:73–80.CrossRef
4.
Zurück zum Zitat Shin MJ, Cho JW. Advances in endoscopic management of biliary complications after living donor liver transplantation: comprehensive review of the literature. World J Gastroenterol. 2016;22:6173–6191.CrossRef Shin MJ, Cho JW. Advances in endoscopic management of biliary complications after living donor liver transplantation: comprehensive review of the literature. World J Gastroenterol. 2016;22:6173–6191.CrossRef
5.
Zurück zum Zitat Ryu CH, Lee SK. Biliary strictures after liver transplantation. Gut Liver. 2011;5:133–142.CrossRef Ryu CH, Lee SK. Biliary strictures after liver transplantation. Gut Liver. 2011;5:133–142.CrossRef
6.
Zurück zum Zitat Chaput U, Scatton O, Bichard P, et al. Temporary placement of partially covered self-expandable metal stents for anastomotic biliary strictures after liver transplantation: a prospective, multicenter study. Gastrointest Endosc. 2010;72:1167–1174.CrossRef Chaput U, Scatton O, Bichard P, et al. Temporary placement of partially covered self-expandable metal stents for anastomotic biliary strictures after liver transplantation: a prospective, multicenter study. Gastrointest Endosc. 2010;72:1167–1174.CrossRef
7.
Zurück zum Zitat Thuluvath PJ, Pfau PR, Kimmey MB, et al. Biliary complications after liver transplantation: the role of endoscopy. Endoscopy. 2005;37:857–863.CrossRef Thuluvath PJ, Pfau PR, Kimmey MB, et al. Biliary complications after liver transplantation: the role of endoscopy. Endoscopy. 2005;37:857–863.CrossRef
8.
Zurück zum Zitat Holt AP, Thorburn D, Mirza D, et al. A prospective study of standardized nonsurgical therapy in the management of biliary anastomotic strictures complicating liver transplantation. Transplantation. 2007;84:857–863.CrossRef Holt AP, Thorburn D, Mirza D, et al. A prospective study of standardized nonsurgical therapy in the management of biliary anastomotic strictures complicating liver transplantation. Transplantation. 2007;84:857–863.CrossRef
9.
Zurück zum Zitat Albert JG, Filmann N, Elsner J, et al. Long-term follow-up of endoscopic therapy for stenosis of the biliobiliary anastomosis associated with orthotopic liver transplantation. Liver Transpl. 2013;19:586–593.CrossRef Albert JG, Filmann N, Elsner J, et al. Long-term follow-up of endoscopic therapy for stenosis of the biliobiliary anastomosis associated with orthotopic liver transplantation. Liver Transpl. 2013;19:586–593.CrossRef
10.
Zurück zum Zitat Poley JW, Lekkerkerker MN, Bruno MJ, et al. Clinical outcome of progressive stenting in patients with anastomotic strictures after orthotopic liver transplantation. Endoscopy. 2013;45:567–570.CrossRef Poley JW, Lekkerkerker MN, Bruno MJ, et al. Clinical outcome of progressive stenting in patients with anastomotic strictures after orthotopic liver transplantation. Endoscopy. 2013;45:567–570.CrossRef
11.
Zurück zum Zitat Morelli J, Mulcahy HE, Draganov P, et al. Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement. Gastrointest Endosc. 2003;58:374–379.CrossRef Morelli J, Mulcahy HE, Draganov P, et al. Long-term outcomes for patients with post-liver transplant anastomotic biliary strictures treated by endoscopic stent placement. Gastrointest Endosc. 2003;58:374–379.CrossRef
12.
Zurück zum Zitat Kao D, Zepeda-Gomez S, Bain VG, et al. Managing the post-liver transplantation anastomotic biliary stricture: multiple plastic versus metal stents: a systematic review. Gastrointest Endosc. 2013;77:679–691.CrossRef Kao D, Zepeda-Gomez S, Bain VG, et al. Managing the post-liver transplantation anastomotic biliary stricture: multiple plastic versus metal stents: a systematic review. Gastrointest Endosc. 2013;77:679–691.CrossRef
13.
Zurück zum Zitat Tabibian JH, Asham EH, Han S, et al. Endoscopic treatment of postorthotopic liver transplantation anastomotic biliary strictures with maximal stent therapy. Gastrointest Endosc. 2010;71:505–512.CrossRef Tabibian JH, Asham EH, Han S, et al. Endoscopic treatment of postorthotopic liver transplantation anastomotic biliary strictures with maximal stent therapy. Gastrointest Endosc. 2010;71:505–512.CrossRef
14.
Zurück zum Zitat Fernández-Simon A, Díaz-Gonzalez A, Cárdenas A, et al. Endoscopic retrograde cholangiography for biliary anastomotic strictures after liver transplantation. Clin Liver Dis. 2014;18:913–926.CrossRef Fernández-Simon A, Díaz-Gonzalez A, Cárdenas A, et al. Endoscopic retrograde cholangiography for biliary anastomotic strictures after liver transplantation. Clin Liver Dis. 2014;18:913–926.CrossRef
15.
Zurück zum Zitat Kahaleh M, Behm B, Clarke BW, et al. Temporary placement of covered self-expandable metal stents in benign biliary strictures: a new paradigm? Gastrointest Endosc. 2008;67:446–454.CrossRef Kahaleh M, Behm B, Clarke BW, et al. Temporary placement of covered self-expandable metal stents in benign biliary strictures: a new paradigm? Gastrointest Endosc. 2008;67:446–454.CrossRef
16.
Zurück zum Zitat Mahajan A, Ho H, Sauer B, et al. Temporary placement of fully covered self-expandable metal stents in benign biliary strictures: midterm evaluation (with video). Gastrointest Endosc. 2009;70:303–309.CrossRef Mahajan A, Ho H, Sauer B, et al. Temporary placement of fully covered self-expandable metal stents in benign biliary strictures: midterm evaluation (with video). Gastrointest Endosc. 2009;70:303–309.CrossRef
17.
Zurück zum Zitat Coté GA, Slivka A, Tarnasky P, et al. Effect of covered metallic stents compared with plastic stents on benign biliary stricture resolution: a randomized clinical trial. JAMA. 2016;315:1250–1257.CrossRef Coté GA, Slivka A, Tarnasky P, et al. Effect of covered metallic stents compared with plastic stents on benign biliary stricture resolution: a randomized clinical trial. JAMA. 2016;315:1250–1257.CrossRef
18.
Zurück zum Zitat Tarantino I, Traina M, Mocciaro F, et al. Fully covered metallic stents in biliary stenosis after orthotopic liver transplantation. Endoscopy. 2012;44:246–250.CrossRef Tarantino I, Traina M, Mocciaro F, et al. Fully covered metallic stents in biliary stenosis after orthotopic liver transplantation. Endoscopy. 2012;44:246–250.CrossRef
19.
Zurück zum Zitat Vandenbroucke F, Plasse M, Dagenais M, et al. Treatment of post liver transplantation bile duct stricture with self-expandable metallic stent. HPB (Oxf). 2006;8:202–205.CrossRef Vandenbroucke F, Plasse M, Dagenais M, et al. Treatment of post liver transplantation bile duct stricture with self-expandable metallic stent. HPB (Oxf). 2006;8:202–205.CrossRef
20.
Zurück zum Zitat Traina M, Tarantino I, Barresi L, et al. Efficacy and safety of fully covered self-expandable metallic stents in biliary complications after liver transplantation: a preliminary study. Liver Transpl. 2009;15:1493–1498.CrossRef Traina M, Tarantino I, Barresi L, et al. Efficacy and safety of fully covered self-expandable metallic stents in biliary complications after liver transplantation: a preliminary study. Liver Transpl. 2009;15:1493–1498.CrossRef
21.
Zurück zum Zitat Pfau P, Pleskow D, Banerjee S, et al. Status evaluation report: Pancreatic and biliary stent. Gastrointest Endosc. 2013;77:319–327.CrossRef Pfau P, Pleskow D, Banerjee S, et al. Status evaluation report: Pancreatic and biliary stent. Gastrointest Endosc. 2013;77:319–327.CrossRef
22.
Zurück zum Zitat García-Pajares F, Sánchez-Antolín G, Pelayo SL, et al. Covered metal stents for the treatment of biliary complications after orthotopic liver transplantation. Transpl Proc. 2010;42:2966–2969.CrossRef García-Pajares F, Sánchez-Antolín G, Pelayo SL, et al. Covered metal stents for the treatment of biliary complications after orthotopic liver transplantation. Transpl Proc. 2010;42:2966–2969.CrossRef
23.
Zurück zum Zitat Jang S, Parsi M, Vargo J, et al. Efficacy and optimal duration of metallic stent in the management of refractory anastomotic stricture after liver transplantation. Clin Gastroenterol Hepatol. 2017;15:1776–1781.CrossRef Jang S, Parsi M, Vargo J, et al. Efficacy and optimal duration of metallic stent in the management of refractory anastomotic stricture after liver transplantation. Clin Gastroenterol Hepatol. 2017;15:1776–1781.CrossRef
24.
Zurück zum Zitat Martins FP, De Paulo GA, Contini M, et al. Metal versus plastic stent for anastomotic biliary strictures after liver transplantation: a randomized controlled trial. Gastrointest Endosc. 2018;87:131–140.CrossRef Martins FP, De Paulo GA, Contini M, et al. Metal versus plastic stent for anastomotic biliary strictures after liver transplantation: a randomized controlled trial. Gastrointest Endosc. 2018;87:131–140.CrossRef
25.
Zurück zum Zitat Kaffes A, Griffin S, Vaughan R, et al. A randomized trial of a fully covered self-expandable metallic stent versus plastic stents in anastomotic biliary strictures after liver transplantation. Ther Adv Gastroenterol. 2014;7:64–71.CrossRef Kaffes A, Griffin S, Vaughan R, et al. A randomized trial of a fully covered self-expandable metallic stent versus plastic stents in anastomotic biliary strictures after liver transplantation. Ther Adv Gastroenterol. 2014;7:64–71.CrossRef
28.
Zurück zum Zitat Martin-Gomez LM, Sobrino-Rodriguez S, Alamo-Martinez JM, et al. Use of fully covered self-expandable stent in biliary complications after liver transplantation: A case series. Transpl Proc. 2010;42:2975–2977.CrossRef Martin-Gomez LM, Sobrino-Rodriguez S, Alamo-Martinez JM, et al. Use of fully covered self-expandable stent in biliary complications after liver transplantation: A case series. Transpl Proc. 2010;42:2975–2977.CrossRef
29.
Zurück zum Zitat DaVee T, Irani S, Baron T, et al. Stent-in-stent technique for removal of embedded partially covered self-expanding metal stents. Surg Endosc. 2016;30:2332–2341.CrossRef DaVee T, Irani S, Baron T, et al. Stent-in-stent technique for removal of embedded partially covered self-expanding metal stents. Surg Endosc. 2016;30:2332–2341.CrossRef
Metadaten
Titel
Self-Expandable Metallic Stent Is More Cost Efficient Than Plastic Stent in Treating Anastomotic Biliary Stricture
verfasst von
Sunguk Jang
Tyler Stevens
Rocio Lopez
Prabhleen Chahal
Amit Bhatt
Madhu Sanaka
John J. Vargo
Publikationsdatum
18.05.2019
Verlag
Springer US
Erschienen in
Digestive Diseases and Sciences / Ausgabe 2/2020
Print ISSN: 0163-2116
Elektronische ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-019-05665-9

Weitere Artikel der Ausgabe 2/2020

Digestive Diseases and Sciences 2/2020 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.