Skip to main content
Erschienen in: Current Bladder Dysfunction Reports 4/2020

09.12.2020 | Neurogenic Bladder (C Powell, Section Editor)

Sexual Health in the Neurogenic Patient

verfasst von: Kirk D. Redger, Alan Quach, Brian J. Flynn

Erschienen in: Current Bladder Dysfunction Reports | Ausgabe 4/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose of Review

In this review, the current literature addressing sexual health in common neurologic conditions will be summarized. Conditions discussed include stroke, multiple sclerosis, spinal cord injury, and spina bifida.

Recent Findings

There is an increasing awareness of sexual dysfunction in patients with neurologic injury and of the role of sexual therapy in improving quality of life.

Summary

Sexual health in a neurogenic patient is dependent upon a variety of factors. Determining the most influential sources of sexual dysfunction is important for providing effective treatment.
Literatur
1.
Zurück zum Zitat Sipski ML, Arenas A. Female sexual function after spinal cord injury. Prog Brain Res. 2006;152:441–7.PubMed Sipski ML, Arenas A. Female sexual function after spinal cord injury. Prog Brain Res. 2006;152:441–7.PubMed
2.
Zurück zum Zitat Harden CL. Sexual dysfunction in women with epilepsy. Seizure. 2008;17:131–5.PubMed Harden CL. Sexual dysfunction in women with epilepsy. Seizure. 2008;17:131–5.PubMed
3.
Zurück zum Zitat Shridharani AN, Brant WO. The treatment of erectile dysfunction in patients with neurogenic disease. Transl Androl Urol. 2016;5(1):88–10.PubMedPubMedCentral Shridharani AN, Brant WO. The treatment of erectile dysfunction in patients with neurogenic disease. Transl Androl Urol. 2016;5(1):88–10.PubMedPubMedCentral
4.
Zurück zum Zitat De Groat WC, Booth AM. Neural control of penile erection. In: Maggi CA, editor. The autonomic nervous system. Switzerland: Harwood Academic Publishers; 1993. p. 467–524. De Groat WC, Booth AM. Neural control of penile erection. In: Maggi CA, editor. The autonomic nervous system. Switzerland: Harwood Academic Publishers; 1993. p. 467–524.
5.
Zurück zum Zitat Clement P, Giuliano F. Physiology and pharmacology of ejaculation. Basic Clin Pharmacol Toxicol. 2016;119:18–25.PubMed Clement P, Giuliano F. Physiology and pharmacology of ejaculation. Basic Clin Pharmacol Toxicol. 2016;119:18–25.PubMed
6.
Zurück zum Zitat Giuliano FA, Rampin O, Benoit G, Jardin A. Neural control of penile erection. Urol Clin North Am. 1995;22:747–66.PubMed Giuliano FA, Rampin O, Benoit G, Jardin A. Neural control of penile erection. Urol Clin North Am. 1995;22:747–66.PubMed
7.
Zurück zum Zitat • Grenier-genest A, Gérard M, Courtois F. Stroke and sexual functioning: a literature review. Neuro Rehabil. 2017;41(2):293–315 This literature review emphasizes the need for sexual rehabilitation in stroke patients’ rehabilitation process. • Grenier-genest A, Gérard M, Courtois F. Stroke and sexual functioning: a literature review. Neuro Rehabil. 2017;41(2):293–315 This literature review emphasizes the need for sexual rehabilitation in stroke patients’ rehabilitation process.
8.
Zurück zum Zitat Steinke EE, Jaarsma T, Barnason SA, Byrne M, Doherty S, Dougherty CM, et al. Sexual counselling for individuals with cardiovascular disease and their partners. Eur Heart J. 2013;34:3217–35.PubMed Steinke EE, Jaarsma T, Barnason SA, Byrne M, Doherty S, Dougherty CM, et al. Sexual counselling for individuals with cardiovascular disease and their partners. Eur Heart J. 2013;34:3217–35.PubMed
9.
Zurück zum Zitat Guo ZN, He SY, Zhang HL, Wu J, Yang Y. Multiple sclerosis and sexual dysfunction. Asian J Androl. 2012;14:530–5.PubMedPubMedCentral Guo ZN, He SY, Zhang HL, Wu J, Yang Y. Multiple sclerosis and sexual dysfunction. Asian J Androl. 2012;14:530–5.PubMedPubMedCentral
10.
Zurück zum Zitat Kessler TM, Fowler CJ, Panicker JN. Sexual dysfunction in multiple sclerosis. Expert Rev Neurother. 2009;9:341–50.PubMed Kessler TM, Fowler CJ, Panicker JN. Sexual dysfunction in multiple sclerosis. Expert Rev Neurother. 2009;9:341–50.PubMed
11.
Zurück zum Zitat Bronner G, Elran E, Golomb J, Korczyn AD. Female sexuality in multiple sclerosis: the multidimensional nature of the problem and the intervention. Acta Neurol Scand. 2010;121:289–301.PubMed Bronner G, Elran E, Golomb J, Korczyn AD. Female sexuality in multiple sclerosis: the multidimensional nature of the problem and the intervention. Acta Neurol Scand. 2010;121:289–301.PubMed
12.
Zurück zum Zitat Sakakibara R, Kishi M, Ogawa E, et al. Bladder, bowel, and sexual dysfunction in Parkinson’s disease. Parkinsons Dis. 2011;924605:1–21. Sakakibara R, Kishi M, Ogawa E, et al. Bladder, bowel, and sexual dysfunction in Parkinson’s disease. Parkinsons Dis. 2011;924605:1–21.
13.
Zurück zum Zitat Lombardi G, Musco S, Kessler TM, Li Marzi V, Lanciotti M, Del Popolo G. Management of sexual dysfunction due to central nervous system disorders: a systematic review. BJU Int. 2015;115(Suppl 6):47–56.PubMed Lombardi G, Musco S, Kessler TM, Li Marzi V, Lanciotti M, Del Popolo G. Management of sexual dysfunction due to central nervous system disorders: a systematic review. BJU Int. 2015;115(Suppl 6):47–56.PubMed
14.
Zurück zum Zitat Kreuter M, Taft C, Siösteen A, Biering-Sørensen F. Women’s sexual functioning and sex life after spinal cord injury. Spinal Cord. 2011;49(1):154–60.PubMed Kreuter M, Taft C, Siösteen A, Biering-Sørensen F. Women’s sexual functioning and sex life after spinal cord injury. Spinal Cord. 2011;49(1):154–60.PubMed
15.
Zurück zum Zitat Cramp JD, Courtois FJ, Ditor DS. Sexuality for women with spinal cord injury. J Sex Marital Ther. 2015;41(3):238–53.PubMed Cramp JD, Courtois FJ, Ditor DS. Sexuality for women with spinal cord injury. J Sex Marital Ther. 2015;41(3):238–53.PubMed
16.
Zurück zum Zitat Forsythe E, Horsewell JE. Sexual rehabilitation of women with a spinal cord injury. Spinal Cord. 2006;44:234–41.PubMed Forsythe E, Horsewell JE. Sexual rehabilitation of women with a spinal cord injury. Spinal Cord. 2006;44:234–41.PubMed
17.
Zurück zum Zitat •• Courtois F, Alexander M, Mclain ABJ. Women’s sexual health and reproductive function after SCI. Top Spinal Cord Inj Rehabil. 2017;23(1):20–30 This article reviews suggestions and treatments for improving the sexual and reproductive function in women after spinal cord injury.PubMedPubMedCentral •• Courtois F, Alexander M, Mclain ABJ. Women’s sexual health and reproductive function after SCI. Top Spinal Cord Inj Rehabil. 2017;23(1):20–30 This article reviews suggestions and treatments for improving the sexual and reproductive function in women after spinal cord injury.PubMedPubMedCentral
18.
Zurück zum Zitat Hess MJ, Hough S. Impact of spinal cord injury on sexuality: broad-based clinical practice intervention and practical application. J Spinal Cord Med. 2012;35(4):211–8.PubMed Hess MJ, Hough S. Impact of spinal cord injury on sexuality: broad-based clinical practice intervention and practical application. J Spinal Cord Med. 2012;35(4):211–8.PubMed
19.
Zurück zum Zitat Alaca R, Goktepe AS, Yildiz N, Yilmaz B, Gunduz S. Effect of penile vibratory stimulation on spasticity in men with spinal cord injury. Am J Phys Med Rehabil. 2005;84(11):875–9.PubMed Alaca R, Goktepe AS, Yildiz N, Yilmaz B, Gunduz S. Effect of penile vibratory stimulation on spasticity in men with spinal cord injury. Am J Phys Med Rehabil. 2005;84(11):875–9.PubMed
20.
Zurück zum Zitat Biering-Sørensen F, Laessøe L, Sønksen J, Bagi P, Nielsen JB, Kristensen JK. The effect of penile vibra- tory stimulation on male fertility potential, spasticity and neurogenic detrusor overactivity in spinal cord lesioned individuals. Acta Neurochir Suppl. 2005;93:159–63.PubMed Biering-Sørensen F, Laessøe L, Sønksen J, Bagi P, Nielsen JB, Kristensen JK. The effect of penile vibra- tory stimulation on male fertility potential, spasticity and neurogenic detrusor overactivity in spinal cord lesioned individuals. Acta Neurochir Suppl. 2005;93:159–63.PubMed
21.
Zurück zum Zitat Courtois F, Geoffrion R, Landry E, Bélnager MH. reflex and physiologic measures of ejaculation in men with spinal cord injury. Arch Phys Med Rehabil. 2004;85:910–8.PubMed Courtois F, Geoffrion R, Landry E, Bélnager MH. reflex and physiologic measures of ejaculation in men with spinal cord injury. Arch Phys Med Rehabil. 2004;85:910–8.PubMed
22.
Zurück zum Zitat Laessøe L, Nielsen JB, Biering-Sørensen F, Sonksen J. Antispastic effect of penile vibration in men with spinal cord lesion. Arch Phys Med Rehabil. 2004;85(6):919–24.PubMed Laessøe L, Nielsen JB, Biering-Sørensen F, Sonksen J. Antispastic effect of penile vibration in men with spinal cord lesion. Arch Phys Med Rehabil. 2004;85(6):919–24.PubMed
23.
Zurück zum Zitat Sonksen J, Ohl DA, Wedemeyer G. Sphincteric events during penile vibratory ejaculation and electroejaculation in men with spinal cord injuries. J Urol. 2001;165(2):426–9.PubMed Sonksen J, Ohl DA, Wedemeyer G. Sphincteric events during penile vibratory ejaculation and electroejaculation in men with spinal cord injuries. J Urol. 2001;165(2):426–9.PubMed
25.
Zurück zum Zitat •• Ibrahim E, Lynne CM, Brackett NL. Male fertility following spinal cord injury: an update. Andrology. 2016;4:13–26 This article reviews suggestions and treatments for improving the sexual and reproductive function in men after spinal cord injury.PubMed •• Ibrahim E, Lynne CM, Brackett NL. Male fertility following spinal cord injury: an update. Andrology. 2016;4:13–26 This article reviews suggestions and treatments for improving the sexual and reproductive function in men after spinal cord injury.PubMed
26.
Zurück zum Zitat • Trofimenko V, Hotaling JM. Fertility treatment in spinal cord injury and other neurologic disease. Transl Androl Urol. 2016;5:102–16 This review addresses the implications of spinal cord injury (SCI) and other neurologic disease on fertility, including the high prevalence of sexual dysfunction, ejaculation disorders and compromised semen parameters.PubMedPubMedCentral • Trofimenko V, Hotaling JM. Fertility treatment in spinal cord injury and other neurologic disease. Transl Androl Urol. 2016;5:102–16 This review addresses the implications of spinal cord injury (SCI) and other neurologic disease on fertility, including the high prevalence of sexual dysfunction, ejaculation disorders and compromised semen parameters.PubMedPubMedCentral
27.
Zurück zum Zitat Anderson KD, Borisof JF, Johnson RD, Stiens SA, Elliott SL. Spinal cord injury infuences psychogenic as well as physical components of female sexual ability. Spinal Cord. 2007;45(5):349–59.PubMed Anderson KD, Borisof JF, Johnson RD, Stiens SA, Elliott SL. Spinal cord injury infuences psychogenic as well as physical components of female sexual ability. Spinal Cord. 2007;45(5):349–59.PubMed
28.
Zurück zum Zitat Anderson KD, Borisof JF, Johnson RD, Stiens SA, Elliott SL. The impact of spinal cord injury on sexual function: concerns of the general population. Spinal Cord. 2007;45(5):328–37.PubMed Anderson KD, Borisof JF, Johnson RD, Stiens SA, Elliott SL. The impact of spinal cord injury on sexual function: concerns of the general population. Spinal Cord. 2007;45(5):328–37.PubMed
29.
Zurück zum Zitat • Gomes CM, Miranda EP, De Bessa J, et al. Erectile function predicts sexual satisfaction in men with spinal cord injury. Sex Med. 2017;5(3):e148–55 This article used the SHIM to evaluate men with spinal cord injury for satisfaction in their sex life.PubMedPubMedCentral • Gomes CM, Miranda EP, De Bessa J, et al. Erectile function predicts sexual satisfaction in men with spinal cord injury. Sex Med. 2017;5(3):e148–55 This article used the SHIM to evaluate men with spinal cord injury for satisfaction in their sex life.PubMedPubMedCentral
30.
Zurück zum Zitat Valtonen K, Karlsson AK, Siösteen A, Dahlöf LG, Viikari-Juntura E. Satisfaction with sexual life among persons with traumatic spinal cord injury and meningomyelocele. Disabil Rehabil. 2006;28:965–76.PubMed Valtonen K, Karlsson AK, Siösteen A, Dahlöf LG, Viikari-Juntura E. Satisfaction with sexual life among persons with traumatic spinal cord injury and meningomyelocele. Disabil Rehabil. 2006;28:965–76.PubMed
31.
Zurück zum Zitat Fisher TL, Laud PW, Byfield MG, Brown TT, Hayat MJ, Fiedler IG. Sexual health after spinal cord injury: a longitudinal study. Arch Phys Med Rehabil. 2002;83:1043–51.PubMed Fisher TL, Laud PW, Byfield MG, Brown TT, Hayat MJ, Fiedler IG. Sexual health after spinal cord injury: a longitudinal study. Arch Phys Med Rehabil. 2002;83:1043–51.PubMed
32.
Zurück zum Zitat Cuenca AIC, Sampietro-Crespo A, Virseda-Chamorro M, Martín-Espinosa N. Psychological impact and sexual dysfunction in men with and without spinal cord injury. J Sex Med. 2015;12:436–44. Cuenca AIC, Sampietro-Crespo A, Virseda-Chamorro M, Martín-Espinosa N. Psychological impact and sexual dysfunction in men with and without spinal cord injury. J Sex Med. 2015;12:436–44.
33.
Zurück zum Zitat Courtois FJ, Charvier KF, Leriche A, Raymond DP. Sexual function in spinal cord injury men. Assessing sexual capability. Paraplegia. Spinal Cord. 1993;31:771–84. Courtois FJ, Charvier KF, Leriche A, Raymond DP. Sexual function in spinal cord injury men. Assessing sexual capability. Paraplegia. Spinal Cord. 1993;31:771–84.
34.
Zurück zum Zitat Stien R. Sexual dysfunction in men with spinal injuries. Tidsskr Nor Laegeforen. 2008;128:453–6.PubMed Stien R. Sexual dysfunction in men with spinal injuries. Tidsskr Nor Laegeforen. 2008;128:453–6.PubMed
35.
Zurück zum Zitat • Anderson R, Moses R, Lenherr S, Hotaling JM, Myers J. Spinal cord injury and male infertility-a review of current literature, knowledge gaps, and future research. Transl Androl Urol. 2018;7(Suppl 3):S373–82 This review highlights how spinal cord injury impacts testicular spermatogenesis, sperm function, semen quality, and overall fecundity.PubMedPubMedCentral • Anderson R, Moses R, Lenherr S, Hotaling JM, Myers J. Spinal cord injury and male infertility-a review of current literature, knowledge gaps, and future research. Transl Androl Urol. 2018;7(Suppl 3):S373–82 This review highlights how spinal cord injury impacts testicular spermatogenesis, sperm function, semen quality, and overall fecundity.PubMedPubMedCentral
36.
Zurück zum Zitat Ergin S, Gunduz B, Ugurlu H, Sivrioglu K, Oncel S, Gok H, et al. A placebo-controlled, multicenter, randomized, double-blind, flexible-dose, two- way crossover study to evaluate the efficacy and safety of sildenafil in men with traumatic spinal cord injury and erectile dysfunction. J Spinal Cord Med. 2008;31:522–31.PubMedPubMedCentral Ergin S, Gunduz B, Ugurlu H, Sivrioglu K, Oncel S, Gok H, et al. A placebo-controlled, multicenter, randomized, double-blind, flexible-dose, two- way crossover study to evaluate the efficacy and safety of sildenafil in men with traumatic spinal cord injury and erectile dysfunction. J Spinal Cord Med. 2008;31:522–31.PubMedPubMedCentral
37.
Zurück zum Zitat Moemen MN, Fahmy I, AbdelAal M, Kamel I, Mansour M, Arafa MM. Erectile dysfunction in spinal cord-injured men: different treatment options. Int J Impot Res. 2008;20:181–7.PubMed Moemen MN, Fahmy I, AbdelAal M, Kamel I, Mansour M, Arafa MM. Erectile dysfunction in spinal cord-injured men: different treatment options. Int J Impot Res. 2008;20:181–7.PubMed
38.
Zurück zum Zitat Giuliano F, Sanchez-Ramos A, Löchner-Ernst D, del Popolo G, Cruz N, Leriche A, et al. Efficacy and safety of tadalafil in men with erectile dysfunction following spinal cord injury. Arch Neurol. 2007;64:1584–92.PubMed Giuliano F, Sanchez-Ramos A, Löchner-Ernst D, del Popolo G, Cruz N, Leriche A, et al. Efficacy and safety of tadalafil in men with erectile dysfunction following spinal cord injury. Arch Neurol. 2007;64:1584–92.PubMed
39.
Zurück zum Zitat Giuliano F, Hultling C, El Masry WS, et al. Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group. Ann Neurol. 1999;46:15–21.PubMed Giuliano F, Hultling C, El Masry WS, et al. Randomized trial of sildenafil for the treatment of erectile dysfunction in spinal cord injury. Sildenafil Study Group. Ann Neurol. 1999;46:15–21.PubMed
40.
Zurück zum Zitat Giuliano F, Rubio-Aurioles E, Kennelly M, Montorsi F, Kim ED, Finkbeiner AE, et al. Efficacy and safety of vardenafil in men with erectile dysfunction caused by spinal cord injury. Neurology. 2006;66:210–6.PubMed Giuliano F, Rubio-Aurioles E, Kennelly M, Montorsi F, Kim ED, Finkbeiner AE, et al. Efficacy and safety of vardenafil in men with erectile dysfunction caused by spinal cord injury. Neurology. 2006;66:210–6.PubMed
41.
Zurück zum Zitat •• Lombardi G, Nelli F, Celso M, Mencarini M, Del Popolo G. Treating erectile dysfunction and central neurological diseases with oral phosphodiesterase type 5 inhibitors. Review of the Literature. J Sex Med. 2018;9(4):970–85 This is a review of oral PDE5 inhibitors in men with erectile dysfunction and various types of central neurological disorders. •• Lombardi G, Nelli F, Celso M, Mencarini M, Del Popolo G. Treating erectile dysfunction and central neurological diseases with oral phosphodiesterase type 5 inhibitors. Review of the Literature. J Sex Med. 2018;9(4):970–85 This is a review of oral PDE5 inhibitors in men with erectile dysfunction and various types of central neurological disorders.
42.
Zurück zum Zitat Sánchez Ramos A, Vidal J, Jáuregui ML, Barrera M, Recio C, Giner M, et al. Efficacy, safety and predictive factors of therapeutic success with sildenafil for erectile dysfunction in patients with different spinal cord injuries. Spinal Cord. 2001;39:637–43.PubMed Sánchez Ramos A, Vidal J, Jáuregui ML, Barrera M, Recio C, Giner M, et al. Efficacy, safety and predictive factors of therapeutic success with sildenafil for erectile dysfunction in patients with different spinal cord injuries. Spinal Cord. 2001;39:637–43.PubMed
43.
Zurück zum Zitat Lombardi G, Macchiarella A, Cecconi F, del Popolo G. Ten-year follow-up of sildenafil use in spinal cord-injured patients with erectile dysfunction. J Sex Med. 2009;6:3449–57.PubMed Lombardi G, Macchiarella A, Cecconi F, del Popolo G. Ten-year follow-up of sildenafil use in spinal cord-injured patients with erectile dysfunction. J Sex Med. 2009;6:3449–57.PubMed
44.
Zurück zum Zitat Lombardi G, Macchiarella A, Cecconi F, del Popolo G. Efficacy and safety of medium and long-term tadalafil use in spinal cord patients with erectile dysfunction. J Sex Med. 2009;6:535–43.PubMed Lombardi G, Macchiarella A, Cecconi F, del Popolo G. Efficacy and safety of medium and long-term tadalafil use in spinal cord patients with erectile dysfunction. J Sex Med. 2009;6:535–43.PubMed
45.
Zurück zum Zitat • Chochina L, Naudet F, Chehensse C, et al. Intracavernous injections in spinal cord injured men with erectile dysfunction, a systematic review and meta-analysis. Sex Med Rev. 2016;4(3):257–69 This literature review focuses on the overall response rate of ICI for ED in patients with spinal cord injury.PubMed • Chochina L, Naudet F, Chehensse C, et al. Intracavernous injections in spinal cord injured men with erectile dysfunction, a systematic review and meta-analysis. Sex Med Rev. 2016;4(3):257–69 This literature review focuses on the overall response rate of ICI for ED in patients with spinal cord injury.PubMed
46.
Zurück zum Zitat Chancellor MB, Rivas DA, Panzer DE, Freedman MK, Staas WE Jr. Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury. Urology. 1994;43:365–9.PubMed Chancellor MB, Rivas DA, Panzer DE, Freedman MK, Staas WE Jr. Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury. Urology. 1994;43:365–9.PubMed
47.
Zurück zum Zitat Zermann D-H, Kutzenberger J, Sauerwein D, Schubert J, Loeffler U. Penile prosthetic surgery in neurologically impaired patients: long-term followup. J Urol. 2006;175(3 Pt 1):1041–4.PubMed Zermann D-H, Kutzenberger J, Sauerwein D, Schubert J, Loeffler U. Penile prosthetic surgery in neurologically impaired patients: long-term followup. J Urol. 2006;175(3 Pt 1):1041–4.PubMed
48.
Zurück zum Zitat Overgoor ML, de Jong TP, Cohen-Kettenis PT, et al. Increased sexual health after restored genital sensation in male patients with spina bifida or a spinal cord injury: the TOMAX procedure. J Urol. 2013;189:626–32.PubMed Overgoor ML, de Jong TP, Cohen-Kettenis PT, et al. Increased sexual health after restored genital sensation in male patients with spina bifida or a spinal cord injury: the TOMAX procedure. J Urol. 2013;189:626–32.PubMed
49.
Zurück zum Zitat Overgoor ML, Braakhekke JP, Kon M, et al. Restoring penis sensation in patients with low spinal cord lesions: the role of the remaining function of the dorsal nerve in a unilateral or bilateral TOMAX procedure. Neurourol Urodyn. 2015;34:343–8.PubMed Overgoor ML, Braakhekke JP, Kon M, et al. Restoring penis sensation in patients with low spinal cord lesions: the role of the remaining function of the dorsal nerve in a unilateral or bilateral TOMAX procedure. Neurourol Urodyn. 2015;34:343–8.PubMed
50.
Zurück zum Zitat Goodin DS. The epidemiology of multiple sclerosis. Handb Clin Neurol Multiple Sclerosis Related Disorders. 2014:231–66. Goodin DS. The epidemiology of multiple sclerosis. Handb Clin Neurol Multiple Sclerosis Related Disorders. 2014:231–66.
51.
Zurück zum Zitat Koch-Henriksen N, Sorensen PS. The changing demographic pattern of multiple sclerosis epidemiology. The Lancet Neurology. 2010;9:520–33.PubMed Koch-Henriksen N, Sorensen PS. The changing demographic pattern of multiple sclerosis epidemiology. The Lancet Neurology. 2010;9:520–33.PubMed
52.
Zurück zum Zitat Barak Y, Achiron A, Elizur A, Gabbay U, Shlomo N, Sarova-Pinhas I. Sexual dysfunction in relapsing-remitting multiple sclerosis: magnetic resonance imaging, clinical, and psychological correlates. J Psychiatry Neurosci. 1996;21:255–8.PubMedPubMedCentral Barak Y, Achiron A, Elizur A, Gabbay U, Shlomo N, Sarova-Pinhas I. Sexual dysfunction in relapsing-remitting multiple sclerosis: magnetic resonance imaging, clinical, and psychological correlates. J Psychiatry Neurosci. 1996;21:255–8.PubMedPubMedCentral
53.
Zurück zum Zitat Lew-Starowicz M, Rola R. Prevalence of sexual dysfunctions among women with multiple sclerosis. Sex Disabil. 2013;31:141–53.PubMedPubMedCentral Lew-Starowicz M, Rola R. Prevalence of sexual dysfunctions among women with multiple sclerosis. Sex Disabil. 2013;31:141–53.PubMedPubMedCentral
54.
Zurück zum Zitat Zorzon M, Zivadinov R, Bosco A, Monti Bragadin L, Moretti R, Bonfigli L, et al. Sexual dysfunction in multiple sclerosis: a case-control study. I. Frequency and comparison of groups. Mult Scler. 1999;5(6):418–27.PubMed Zorzon M, Zivadinov R, Bosco A, Monti Bragadin L, Moretti R, Bonfigli L, et al. Sexual dysfunction in multiple sclerosis: a case-control study. I. Frequency and comparison of groups. Mult Scler. 1999;5(6):418–27.PubMed
55.
Zurück zum Zitat Tudor K, Eames S, Haslam C, Chataway J, Liechti M, Panicker J. Identifying barriers to help-seeking for sexual dysfunction in multiple sclerosis. J Neurol. 2018;265(12):2789–802.PubMed Tudor K, Eames S, Haslam C, Chataway J, Liechti M, Panicker J. Identifying barriers to help-seeking for sexual dysfunction in multiple sclerosis. J Neurol. 2018;265(12):2789–802.PubMed
56.
Zurück zum Zitat •• Bartnik P, Wielgoś A, Kacperczyk J, Pisarz K, Szymusik I, Podlecka-Piętowska A, et al. Sexual dysfunction in female patients with relapsing-remitting multiple sclerosis. Brain and Behavior. 2017;7(6):e00699 This trial describes the association between various clinical and demographic variables and different levels of sexual dysfunction in women with multiple sclerosis.PubMedPubMedCentral •• Bartnik P, Wielgoś A, Kacperczyk J, Pisarz K, Szymusik I, Podlecka-Piętowska A, et al. Sexual dysfunction in female patients with relapsing-remitting multiple sclerosis. Brain and Behavior. 2017;7(6):e00699 This trial describes the association between various clinical and demographic variables and different levels of sexual dysfunction in women with multiple sclerosis.PubMedPubMedCentral
57.
Zurück zum Zitat Kisic-tepavcevic D, Pekmezovic T, Trajkovic G, et al. Sexual dysfunction in multiple sclerosis: a 6-year follow-up study. J Neurol Sci. 2015;358(1–2):317–23.PubMed Kisic-tepavcevic D, Pekmezovic T, Trajkovic G, et al. Sexual dysfunction in multiple sclerosis: a 6-year follow-up study. J Neurol Sci. 2015;358(1–2):317–23.PubMed
58.
Zurück zum Zitat Cordeau D, Courtois F, Beaulieu-Pre’vost D, Be’langer M. Sexual disorders in women with multiple sclerosis: assessment and management. Ann Phys Rehabil Med. 2014;57:337–47.PubMed Cordeau D, Courtois F, Beaulieu-Pre’vost D, Be’langer M. Sexual disorders in women with multiple sclerosis: assessment and management. Ann Phys Rehabil Med. 2014;57:337–47.PubMed
59.
Zurück zum Zitat Betts CD, Jones SJ, Fowler CG, et al. Erectile dysfunction in multiple sclerosis. Associated neurological and neurophysiological deficits, and treatment of the condition. Brain. 1994;117:1303–10.PubMed Betts CD, Jones SJ, Fowler CG, et al. Erectile dysfunction in multiple sclerosis. Associated neurological and neurophysiological deficits, and treatment of the condition. Brain. 1994;117:1303–10.PubMed
60.
Zurück zum Zitat Fowler CJ, Miller JR, Sharief MK, Hussain IF, Stecher VJ, Sweeney M. A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2005;76:700–5.PubMedPubMedCentral Fowler CJ, Miller JR, Sharief MK, Hussain IF, Stecher VJ, Sweeney M. A double blind, randomised study of sildenafil citrate for erectile dysfunction in men with multiple sclerosis. J Neurol Neurosurg Psychiatry. 2005;76:700–5.PubMedPubMedCentral
61.
Zurück zum Zitat Lombardi G, Macchiarella A, Del Popolo G. Efficacy and safety of tadalafil for erectile dysfunction in patients with multiple sclerosis. J Sex Med. 2010;7:2192–200.PubMed Lombardi G, Macchiarella A, Del Popolo G. Efficacy and safety of tadalafil for erectile dysfunction in patients with multiple sclerosis. J Sex Med. 2010;7:2192–200.PubMed
62.
Zurück zum Zitat Safarinejad MR. Evaluation of the safety and efficacy of sildenafil citrate for erectile dysfunction in men with multiple sclerosis: a double-blind, placebo controlled, randomized study. J Urol. 2009;181:252–8.PubMed Safarinejad MR. Evaluation of the safety and efficacy of sildenafil citrate for erectile dysfunction in men with multiple sclerosis: a double-blind, placebo controlled, randomized study. J Urol. 2009;181:252–8.PubMed
63.
Zurück zum Zitat Kirkeby HJ, Petersen T, Poulsen EU. Pharmacologically induced erection in patients with multiple sclerosis. Scand J Urol Nephrol. 1988;22:241–4.PubMed Kirkeby HJ, Petersen T, Poulsen EU. Pharmacologically induced erection in patients with multiple sclerosis. Scand J Urol Nephrol. 1988;22:241–4.PubMed
64.
Zurück zum Zitat Prévinaire JG, Lecourt G, Soler JM, Denys P. Sexual disorders in men with multiple sclerosis: evaluation and management. Ann Phys Rehabil Med. 2014;57(5):329–36.PubMed Prévinaire JG, Lecourt G, Soler JM, Denys P. Sexual disorders in men with multiple sclerosis: evaluation and management. Ann Phys Rehabil Med. 2014;57(5):329–36.PubMed
65.
Zurück zum Zitat Foley FW, LaRocca NG, Sanders AS, Zemon V. Rehabilitation of intimacy and sexual dysfunction in couples with multiple sclerosis. Mult Scler. 2001;7:417–21.PubMed Foley FW, LaRocca NG, Sanders AS, Zemon V. Rehabilitation of intimacy and sexual dysfunction in couples with multiple sclerosis. Mult Scler. 2001;7:417–21.PubMed
66.
Zurück zum Zitat Sanders AS, Foley FW, LaRocca GL, Zemon V. The multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19). Sex Disabil. 2000;18:3–26. Sanders AS, Foley FW, LaRocca GL, Zemon V. The multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19). Sex Disabil. 2000;18:3–26.
67.
Zurück zum Zitat Foley F, Zemon V, Campagnolo D, Marrie R, Cutter G, Tyry T, et al. The Multiple Sclerosis Intimacy and Sexuality Questionnaire — re-validation and development of a 15-item version with a large US sample. Mult Scler J. 2013;19(9):1197–203. Foley F, Zemon V, Campagnolo D, Marrie R, Cutter G, Tyry T, et al. The Multiple Sclerosis Intimacy and Sexuality Questionnaire — re-validation and development of a 15-item version with a large US sample. Mult Scler J. 2013;19(9):1197–203.
68.
Zurück zum Zitat Zamani M, Tavoli A, Yazd Khasti B, Sedighimornani N, Zafar M. Sexual therapy for women with multiple sclerosis and its impact on quality of life. Iran J Psychiatry. 2017;12(1):58–65.PubMedPubMedCentral Zamani M, Tavoli A, Yazd Khasti B, Sedighimornani N, Zafar M. Sexual therapy for women with multiple sclerosis and its impact on quality of life. Iran J Psychiatry. 2017;12(1):58–65.PubMedPubMedCentral
69.
Zurück zum Zitat Calabrò R, De Luca R, Conti-Nibali V, Reitano S, Leo A, Bramanti P. Sexual dysfunction in male patients with multiple sclerosis: a need for counseling! Int J Neurosci. 2013;124(8):547–57.PubMed Calabrò R, De Luca R, Conti-Nibali V, Reitano S, Leo A, Bramanti P. Sexual dysfunction in male patients with multiple sclerosis: a need for counseling! Int J Neurosci. 2013;124(8):547–57.PubMed
71.
Zurück zum Zitat Verhoef M, Barf HA, Vroege JA, Post MW, Van Asbeck FW, Gooskens RH, et al. Sex education, relationships, and sexuality in young adults with spina bifida. Arch Phys Med Rehabil. 2005;86:979e87. Verhoef M, Barf HA, Vroege JA, Post MW, Van Asbeck FW, Gooskens RH, et al. Sex education, relationships, and sexuality in young adults with spina bifida. Arch Phys Med Rehabil. 2005;86:979e87.
72.
Zurück zum Zitat Sawyer SM, Roberts KV. Sexual and reproductive health in young people with spina bifida. Dev Med Child Neurol. 1999;41:671e5. Sawyer SM, Roberts KV. Sexual and reproductive health in young people with spina bifida. Dev Med Child Neurol. 1999;41:671e5.
73.
Zurück zum Zitat Lassman J, Gonzalez FG, Melchionnia JB, et al. Sexual function in adult patients with spina bifida and its impact on quality of life. J Urol. 2007;178:1611–4. Lassman J, Gonzalez FG, Melchionnia JB, et al. Sexual function in adult patients with spina bifida and its impact on quality of life. J Urol. 2007;178:1611–4.
74.
Zurück zum Zitat Lee NG, Andrews E, Rosoklija I, et al. The effect of spinal cord level on sexual function in the spina bifida population. J Pediatr Urol. 2015;11:142.e1–6. Lee NG, Andrews E, Rosoklija I, et al. The effect of spinal cord level on sexual function in the spina bifida population. J Pediatr Urol. 2015;11:142.e1–6.
75.
Zurück zum Zitat Cardenas DD, Topolski TD, White CJ, McLaughlin JF, Walker WO. Sexual functioning in adolescents and young adults with spina bifida. Arch Phys Med Rehabil. 2008;89:31–5.PubMed Cardenas DD, Topolski TD, White CJ, McLaughlin JF, Walker WO. Sexual functioning in adolescents and young adults with spina bifida. Arch Phys Med Rehabil. 2008;89:31–5.PubMed
76.
Zurück zum Zitat Gatti C, Del Rossi C, Ferrari A, et al. Predictors of successful sexual partnering of adults with spina bifida. J Urol. 2009;182:1911–6.PubMed Gatti C, Del Rossi C, Ferrari A, et al. Predictors of successful sexual partnering of adults with spina bifida. J Urol. 2009;182:1911–6.PubMed
77.
Zurück zum Zitat Diamond DA, Rickwood AM, Thomas DG. Penile erections in myelomeningocele patients. Br J Urol. 1986;58:434–5.PubMed Diamond DA, Rickwood AM, Thomas DG. Penile erections in myelomeningocele patients. Br J Urol. 1986;58:434–5.PubMed
78.
Zurück zum Zitat Game X, Moscovici J, Game L, et al. Evaluation of sexual function in young men with spina bifida and myelomeningocele using the International Index of Erectile Function. Urology. 2006;67:566–70.PubMed Game X, Moscovici J, Game L, et al. Evaluation of sexual function in young men with spina bifida and myelomeningocele using the International Index of Erectile Function. Urology. 2006;67:566–70.PubMed
79.
Zurück zum Zitat Shurtleff DB, Hayden PW, Chapman WH, Broy AB, Hill ML. Myelodysplasia. Problems of long-term survival and social function. West J Med. 1975;122:199–205.PubMedPubMedCentral Shurtleff DB, Hayden PW, Chapman WH, Broy AB, Hill ML. Myelodysplasia. Problems of long-term survival and social function. West J Med. 1975;122:199–205.PubMedPubMedCentral
80.
Zurück zum Zitat Palmer JS, Kaplan WE, Firlit CF. Erectile dysfunction in patients with spina bifida is a treatable condition. J Urol. 2000;164:958–61.PubMed Palmer JS, Kaplan WE, Firlit CF. Erectile dysfunction in patients with spina bifida is a treatable condition. J Urol. 2000;164:958–61.PubMed
81.
Zurück zum Zitat Palmer JS, Kaplan WE, Firlit CF. Erectile dysfunction in spina bifida is treatable. Lancet. 1999;354:125–6.PubMed Palmer JS, Kaplan WE, Firlit CF. Erectile dysfunction in spina bifida is treatable. Lancet. 1999;354:125–6.PubMed
82.
Zurück zum Zitat Caplan L. Caplan's stroke. Philadelphia: Elsevier/Saunders; 2009. Caplan L. Caplan's stroke. Philadelphia: Elsevier/Saunders; 2009.
83.
Zurück zum Zitat Wityk RJ, Llinas RH. Stroke. Philadelphia: The American College of Physicians; 2016. Wityk RJ, Llinas RH. Stroke. Philadelphia: The American College of Physicians; 2016.
84.
Zurück zum Zitat Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7.PubMed Strong K, Mathers C, Bonita R. Preventing stroke: saving lives around the world. Lancet Neurol. 2007;6:182–7.PubMed
85.
Zurück zum Zitat Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, et al. Age at stroke: temporal trends in stroke incidence in a large, biracial population. Neurology. 2012;79(17):1781–7.PubMedPubMedCentral Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, et al. Age at stroke: temporal trends in stroke incidence in a large, biracial population. Neurology. 2012;79(17):1781–7.PubMedPubMedCentral
86.
Zurück zum Zitat Kimura M, Murata Y, Shimoda K, Robinson RG. Sexual dysfunction following stroke. Compr Psychiatry. 2001;42:217–22.PubMed Kimura M, Murata Y, Shimoda K, Robinson RG. Sexual dysfunction following stroke. Compr Psychiatry. 2001;42:217–22.PubMed
87.
Zurück zum Zitat Bener A, Al-Hamaq AO, Kamran S, et al. Prevalence of erectile dysfunction in male stroke patients, and associated co-morbidities and risk factors. Int Urol Nephrol. 2008;40:701–8.PubMed Bener A, Al-Hamaq AO, Kamran S, et al. Prevalence of erectile dysfunction in male stroke patients, and associated co-morbidities and risk factors. Int Urol Nephrol. 2008;40:701–8.PubMed
88.
Zurück zum Zitat Korpelainen JT, Nieminen P, Myllyla VV. Sexual functioning among stroke patients and their spouses. Stroke. 1999;30:715–9.PubMed Korpelainen JT, Nieminen P, Myllyla VV. Sexual functioning among stroke patients and their spouses. Stroke. 1999;30:715–9.PubMed
89.
Zurück zum Zitat Korpelainen JT, Kauhanen ML, Kemola H, Malinen U, Myllyla VV. Sexual dysfunction in stroke patients. Acta Neurol Scand. 1998;98:400–5.PubMed Korpelainen JT, Kauhanen ML, Kemola H, Malinen U, Myllyla VV. Sexual dysfunction in stroke patients. Acta Neurol Scand. 1998;98:400–5.PubMed
90.
Zurück zum Zitat Monga TN, Lawson JS, Inglis J. Sexual dysfunction in stroke patients. Arch Phys Med Rehabil. 1986;67:19–22.PubMed Monga TN, Lawson JS, Inglis J. Sexual dysfunction in stroke patients. Arch Phys Med Rehabil. 1986;67:19–22.PubMed
91.
Zurück zum Zitat Coslett HB, Heilman KM. Male sexual function: impairment after right hemisphere stroke. Arch Neurol. 1986;43(10):1036–9.PubMed Coslett HB, Heilman KM. Male sexual function: impairment after right hemisphere stroke. Arch Neurol. 1986;43(10):1036–9.PubMed
92.
Zurück zum Zitat Braun CJ, Dumont M, Duval J, et al. Opposed left and right brain hemisphere contributions to sexual drive: a multiple lesion case analysis. Behav Neurol. 2013;14:55–61. Braun CJ, Dumont M, Duval J, et al. Opposed left and right brain hemisphere contributions to sexual drive: a multiple lesion case analysis. Behav Neurol. 2013;14:55–61.
93.
Zurück zum Zitat Boldrini P, Basaglia N, Calanca MC. Sexual changes in hemiparetic patients. Arch Phys Med Rehabil. 1991;72(3):202–7.PubMed Boldrini P, Basaglia N, Calanca MC. Sexual changes in hemiparetic patients. Arch Phys Med Rehabil. 1991;72(3):202–7.PubMed
94.
Zurück zum Zitat Cheung RT. Sexual functioning in Chinese stroke patients with mild or no disability. Cerebrovasc Dis. 2002;14(2):122–8.PubMed Cheung RT. Sexual functioning in Chinese stroke patients with mild or no disability. Cerebrovasc Dis. 2002;14(2):122–8.PubMed
95.
Zurück zum Zitat Choi-Kwon S, Kim JS. Post-stroke emotional incontinence and decreased sexual activity. Cerebrovasc Dis. 2002;12(1):31–7. Choi-Kwon S, Kim JS. Post-stroke emotional incontinence and decreased sexual activity. Cerebrovasc Dis. 2002;12(1):31–7.
96.
Zurück zum Zitat Giaquinto S, Buzzelli S, Di Francesco L, Nolfe G. Evaluation of sexual changes after stroke. J Clin Psychiatry. 2003;64:302–7.PubMed Giaquinto S, Buzzelli S, Di Francesco L, Nolfe G. Evaluation of sexual changes after stroke. J Clin Psychiatry. 2003;64:302–7.PubMed
97.
Zurück zum Zitat Tamam Y, Tamam L, Akil E, Yasan A, Tamam B. Post-stroke sexual functioning in first stroke patients. Eur J Neurol. 2008;15(7):660–6.PubMed Tamam Y, Tamam L, Akil E, Yasan A, Tamam B. Post-stroke sexual functioning in first stroke patients. Eur J Neurol. 2008;15(7):660–6.PubMed
98.
Zurück zum Zitat McLaughlin J, Cregan A. Sexuality in stroke care: a neglected quality of life issue in stroke rehabilitation? A pilot study. Sex Disabil. 2005;23(4):213–26. McLaughlin J, Cregan A. Sexuality in stroke care: a neglected quality of life issue in stroke rehabilitation? A pilot study. Sex Disabil. 2005;23(4):213–26.
99.
Zurück zum Zitat Guo M, Bosnyak S, Bontempo T, et al. Let’s talk about sex! – improving sexual health for patient in stroke rehabilitation. BMJ Qual Improve Rep. 2015;4(1):1–4. Guo M, Bosnyak S, Bontempo T, et al. Let’s talk about sex! – improving sexual health for patient in stroke rehabilitation. BMJ Qual Improve Rep. 2015;4(1):1–4.
100.
Zurück zum Zitat Alexander M, Rosen RC. Spinal cord injuries and orgasm: a review. J Sex Marital Ther. 2008;34(4):308–24.PubMed Alexander M, Rosen RC. Spinal cord injuries and orgasm: a review. J Sex Marital Ther. 2008;34(4):308–24.PubMed
101.
Zurück zum Zitat Field-Fote E. Spinal cord injury rehabilitation. Philadelphia: F.A. Davis; 2009. Field-Fote E. Spinal cord injury rehabilitation. Philadelphia: F.A. Davis; 2009.
102.
Zurück zum Zitat Tepper MS, Whipple B, Richards E, Komisaruk BR. Women with complete spinal cord injury: a phenomenological study of sexual experiences. J Sex Marital Ther. 2001;27(5):615–23.PubMed Tepper MS, Whipple B, Richards E, Komisaruk BR. Women with complete spinal cord injury: a phenomenological study of sexual experiences. J Sex Marital Ther. 2001;27(5):615–23.PubMed
103.
Zurück zum Zitat Bérard E. The sexuality of spinal cord injured women: physiology and pathophysiology. A review Paraplegia. 1989;27(2):99–112.PubMed Bérard E. The sexuality of spinal cord injured women: physiology and pathophysiology. A review Paraplegia. 1989;27(2):99–112.PubMed
104.
Zurück zum Zitat Whipple B, Gerdes CA, Komisaruk BR. Sexual response to self-stimulation in women with complete spinal cord injury. J Sex Res. 1996;33(3):231–40. Whipple B, Gerdes CA, Komisaruk BR. Sexual response to self-stimulation in women with complete spinal cord injury. J Sex Res. 1996;33(3):231–40.
106.
Zurück zum Zitat Sipski ML, Alexander CJ, Gomez-Marin O, Grossbard M, Rosen R. Effects of vibratory stimulation on sexual response in women with spinal cord injury. J Rehabil Res Dev. 2005;42:609–16.PubMed Sipski ML, Alexander CJ, Gomez-Marin O, Grossbard M, Rosen R. Effects of vibratory stimulation on sexual response in women with spinal cord injury. J Rehabil Res Dev. 2005;42:609–16.PubMed
107.
Zurück zum Zitat Alexander MS, Rosen RC, Steinberg S, Symonds T, Haughie S, Hultling C. Sildenafil in women with sexual arousal disorder following spinal cord injury. Spinal Cord. 2011;49:273–9.PubMed Alexander MS, Rosen RC, Steinberg S, Symonds T, Haughie S, Hultling C. Sildenafil in women with sexual arousal disorder following spinal cord injury. Spinal Cord. 2011;49:273–9.PubMed
108.
Zurück zum Zitat Basson R. A model of women’s sexual arousal. J Sex Marital Ther. 2002;28:1–10.PubMed Basson R. A model of women’s sexual arousal. J Sex Marital Ther. 2002;28:1–10.PubMed
109.
Zurück zum Zitat Basson R, Leiblum S, Brotto L, Derogatis L, Fourcroy J, Fugl-Meyer K, et al. Revised definitions of women’s sexual dysfunction. J Sex Med. 2004;1:40–8.PubMed Basson R, Leiblum S, Brotto L, Derogatis L, Fourcroy J, Fugl-Meyer K, et al. Revised definitions of women’s sexual dysfunction. J Sex Med. 2004;1:40–8.PubMed
110.
Zurück zum Zitat Sipski LM, Alexander CJ, Rosen R. Orgasm in women with spinal cord injuries: a laboratory-based assessment. Arch Phys Med Rehabil. 1995;76:1097–102.PubMed Sipski LM, Alexander CJ, Rosen R. Orgasm in women with spinal cord injuries: a laboratory-based assessment. Arch Phys Med Rehabil. 1995;76:1097–102.PubMed
111.
Zurück zum Zitat Sipski ML, Alexander CJ, Rosen RC. Physiological parameters associated with psychogenic sexual arousal in women with complete spinal cord injuries. Arch Phys Med Rehabil. 1995;76(9):811–8.PubMed Sipski ML, Alexander CJ, Rosen RC. Physiological parameters associated with psychogenic sexual arousal in women with complete spinal cord injuries. Arch Phys Med Rehabil. 1995;76(9):811–8.PubMed
112.
Zurück zum Zitat Sipski ML, Alexander CJ, Rosen RC. Physiological parameters associated with sexual arousal in women with incomplete spinal injury. Arch Phys Med Rehabil. 1997;78:305–13.PubMed Sipski ML, Alexander CJ, Rosen RC. Physiological parameters associated with sexual arousal in women with incomplete spinal injury. Arch Phys Med Rehabil. 1997;78:305–13.PubMed
113.
Zurück zum Zitat Sipski LM, Alexander CJ, Rosen RC. Sexual arousal and orgasm in women: effects of spinal cord injury. Ann Neurol. 2001;49:35–44.PubMed Sipski LM, Alexander CJ, Rosen RC. Sexual arousal and orgasm in women: effects of spinal cord injury. Ann Neurol. 2001;49:35–44.PubMed
114.
Zurück zum Zitat Courtois F, Charvier K. Sexual dysfunction in patients with spinal cord lesions. Handb Clin Neurol. 2015;130:225–45.PubMed Courtois F, Charvier K. Sexual dysfunction in patients with spinal cord lesions. Handb Clin Neurol. 2015;130:225–45.PubMed
115.
Zurück zum Zitat Courtois F, Charvier K, Bélanger D, et al. Clinical approach to anorgasmia in women with spinal cord injury. J Sex Med. 2011;8(suppl 5):380. Courtois F, Charvier K, Bélanger D, et al. Clinical approach to anorgasmia in women with spinal cord injury. J Sex Med. 2011;8(suppl 5):380.
116.
Zurück zum Zitat Fenstermaker M, Dupree JM, Hadj-moussa M, Ohl DA. Management of erectile dysfunction and infertility in the male spinal cord injury patient. Curr Urol Rep. 2018;19(7):47.PubMed Fenstermaker M, Dupree JM, Hadj-moussa M, Ohl DA. Management of erectile dysfunction and infertility in the male spinal cord injury patient. Curr Urol Rep. 2018;19(7):47.PubMed
117.
Zurück zum Zitat Brackett NL, Ibrahim E, Iremashvili V, Aballa TC, Lynne CM. Treatment for ejaculatory dysfunction in men with spinal cord injury: an 18-year single center experience. J Urol. 2010;183:2304–8.PubMed Brackett NL, Ibrahim E, Iremashvili V, Aballa TC, Lynne CM. Treatment for ejaculatory dysfunction in men with spinal cord injury: an 18-year single center experience. J Urol. 2010;183:2304–8.PubMed
118.
Zurück zum Zitat Chéhensse C, Bahrami S, Denys P, Clément P, Bernabé J, Giuliano F. The spinal control of ejaculation revisited: a systematic review and meta-analysis of anejaculation in spinal cord injured patients. Hum Reprod Update. 2013;19:507–26.PubMed Chéhensse C, Bahrami S, Denys P, Clément P, Bernabé J, Giuliano F. The spinal control of ejaculation revisited: a systematic review and meta-analysis of anejaculation in spinal cord injured patients. Hum Reprod Update. 2013;19:507–26.PubMed
119.
Zurück zum Zitat Ohl DA, Bennett CJ, McCabe M, Menge AC, McGuire EJ. Predictors of success in electroejaculation of spinal cord injured men. J Urol. 1989;142:1483–6.PubMed Ohl DA, Bennett CJ, McCabe M, Menge AC, McGuire EJ. Predictors of success in electroejaculation of spinal cord injured men. J Urol. 1989;142:1483–6.PubMed
120.
Zurück zum Zitat Cass AS, Bloom BA, Luxenberg M. Sexual function in adults with myelomeningocele. J Urol. 1986;136:425–6.PubMed Cass AS, Bloom BA, Luxenberg M. Sexual function in adults with myelomeningocele. J Urol. 1986;136:425–6.PubMed
121.
Zurück zum Zitat Decter RM, Furness PD 3rd, Nguyen TA, et al. Reproductive understanding, sexual functioning and testosterone levels in men with spina bifida. J Urol. 1997;157:1466–8.PubMed Decter RM, Furness PD 3rd, Nguyen TA, et al. Reproductive understanding, sexual functioning and testosterone levels in men with spina bifida. J Urol. 1997;157:1466–8.PubMed
122.
Zurück zum Zitat Hirayama A, Yamada K, Tanaka Y, Hirata N, Yamamoto M, Suemori T, et al. Evaluation of sexual function in adults with myelomeningocele. Hinyokika Kiyo. 1995;41:985–9.PubMed Hirayama A, Yamada K, Tanaka Y, Hirata N, Yamamoto M, Suemori T, et al. Evaluation of sexual function in adults with myelomeningocele. Hinyokika Kiyo. 1995;41:985–9.PubMed
123.
Zurück zum Zitat Hsieh MH, Hollander A, Lamb DJ, Turek PJ. The genetic and phenotypic basis of infertility in men with pediatric urologic disorders. Urology. 2010;76:25–31.PubMedPubMedCentral Hsieh MH, Hollander A, Lamb DJ, Turek PJ. The genetic and phenotypic basis of infertility in men with pediatric urologic disorders. Urology. 2010;76:25–31.PubMedPubMedCentral
124.
Zurück zum Zitat •• Ibrahim E, Brackett NL, Lynne CM. Advances in the management of infertility in men with spinal cord injury. Asian J Androl. 2016;18(3):382–90 This article argues for an emphasis on trying simple methods of penile vibratory stimulation or electroejaculation before resorting to more advanced and invasive surgical procedures in men with spinal cord injury.PubMedPubMedCentral •• Ibrahim E, Brackett NL, Lynne CM. Advances in the management of infertility in men with spinal cord injury. Asian J Androl. 2016;18(3):382–90 This article argues for an emphasis on trying simple methods of penile vibratory stimulation or electroejaculation before resorting to more advanced and invasive surgical procedures in men with spinal cord injury.PubMedPubMedCentral
125.
Zurück zum Zitat Sonksen J, Biering-Sorensen F, Kristensen JK. Ejaculation induced by penile vibratory stimulation in men with spinal cord injuries. The importance of the vibratory amplitude. Paraplegia. 1994;32:651–60.PubMed Sonksen J, Biering-Sorensen F, Kristensen JK. Ejaculation induced by penile vibratory stimulation in men with spinal cord injuries. The importance of the vibratory amplitude. Paraplegia. 1994;32:651–60.PubMed
126.
Zurück zum Zitat Courtois F, Charvier K, Leriche A. Perceived physiological and orgasmic sensations at ejaculation in spinal cord injured men. J Sex Med. 2008;5:2419–30.PubMed Courtois F, Charvier K, Leriche A. Perceived physiological and orgasmic sensations at ejaculation in spinal cord injured men. J Sex Med. 2008;5:2419–30.PubMed
127.
Zurück zum Zitat Soler JM, Previnaire JG, Plante P, Denys P, Chartier-Kastler E. Midodrine improves ejaculation in spinal cord injured men. J Urol. 2007;178:2082–6.PubMed Soler JM, Previnaire JG, Plante P, Denys P, Chartier-Kastler E. Midodrine improves ejaculation in spinal cord injured men. J Urol. 2007;178:2082–6.PubMed
128.
Zurück zum Zitat Safarinejad MR. Midodrine for the treatment of organic anejaculation but not spinal cord injury: a prospective randomized placebo-controlled double-blind clinical study. Int J Impot Res. 2009;21:213–20.PubMed Safarinejad MR. Midodrine for the treatment of organic anejaculation but not spinal cord injury: a prospective randomized placebo-controlled double-blind clinical study. Int J Impot Res. 2009;21:213–20.PubMed
129.
Zurück zum Zitat Ohl DA, Quallich SA, Sonksen J, et al. Anejaculation and retrograde ejaculation. Urol Clin North Am. 2008;35:211–20 viii.PubMed Ohl DA, Quallich SA, Sonksen J, et al. Anejaculation and retrograde ejaculation. Urol Clin North Am. 2008;35:211–20 viii.PubMed
130.
Zurück zum Zitat Kamischke A, Nieschlag E. Update on medical treatment of ejaculatory disorders. Int J Androl. 2002;25:333–44.PubMed Kamischke A, Nieschlag E. Update on medical treatment of ejaculatory disorders. Int J Androl. 2002;25:333–44.PubMed
131.
Zurück zum Zitat Gilja I, Parazajder J, Radej M, et al. Retrograde ejaculation and loss of emission: possibilities of conservative treatment. Eur Urol. 1994;25:226–8.PubMed Gilja I, Parazajder J, Radej M, et al. Retrograde ejaculation and loss of emission: possibilities of conservative treatment. Eur Urol. 1994;25:226–8.PubMed
132.
Zurück zum Zitat Ohl DA, Menge AC, Sonksen J. Penile vibratory stimulation in spinal cord injured men: optimized vibration parameters and prog- nostic factors. Arch Phys Med Rehabil. 1996;77(9):903–5.PubMed Ohl DA, Menge AC, Sonksen J. Penile vibratory stimulation in spinal cord injured men: optimized vibration parameters and prog- nostic factors. Arch Phys Med Rehabil. 1996;77(9):903–5.PubMed
133.
Zurück zum Zitat Chong W, Ibrahim E, Aballa TC, Lynne CM, Brackett NL. Comparison of three methods of penile vibratory stimulation for semen retrieval in men with spinal cord injury. Spinal Cord. 2017;55(10):921–5.PubMed Chong W, Ibrahim E, Aballa TC, Lynne CM, Brackett NL. Comparison of three methods of penile vibratory stimulation for semen retrieval in men with spinal cord injury. Spinal Cord. 2017;55(10):921–5.PubMed
134.
Zurück zum Zitat Crich JP, Jequier AM. Infertility in men with retrograde ejaculation: the action of urine on sperm motility, and a simple method for achieving antegrade ejaculation. Fertil Steril. 1978;30:572–6.PubMed Crich JP, Jequier AM. Infertility in men with retrograde ejaculation: the action of urine on sperm motility, and a simple method for achieving antegrade ejaculation. Fertil Steril. 1978;30:572–6.PubMed
135.
Zurück zum Zitat Suominen JJ, Kilkku PP, Taina EJ, Puntala PV, et al. Int J Androl. 1991;14:87–90.PubMed Suominen JJ, Kilkku PP, Taina EJ, Puntala PV, et al. Int J Androl. 1991;14:87–90.PubMed
136.
Zurück zum Zitat Hultling C, Levi R, Amark SP, et al. Semen retrieval and analysis in men with myelomeningocele. Dev Med Child Neurol. 2000;42:681–4.PubMed Hultling C, Levi R, Amark SP, et al. Semen retrieval and analysis in men with myelomeningocele. Dev Med Child Neurol. 2000;42:681–4.PubMed
137.
Zurück zum Zitat Kafetsoulis A, Brackett NL, Ibrahim E, Attia GR, Lynne CM. Current trends in the treatment of infertility in men with spinal cord injury. Fertil Steril. 2006;86:781–9.PubMed Kafetsoulis A, Brackett NL, Ibrahim E, Attia GR, Lynne CM. Current trends in the treatment of infertility in men with spinal cord injury. Fertil Steril. 2006;86:781–9.PubMed
138.
Zurück zum Zitat Ohl DA, Sonksen J, Menge AC. Electroejaculation versus vibratory stimulation in spinal cord injured men: sperm quality and patient preference. J Urol. 1997;157:2147–9.PubMed Ohl DA, Sonksen J, Menge AC. Electroejaculation versus vibratory stimulation in spinal cord injured men: sperm quality and patient preference. J Urol. 1997;157:2147–9.PubMed
139.
Zurück zum Zitat Iremashvili V, Brackett NL, Ibrahim E, Aballa TC, Lynne CM. The choice of assisted ejaculation method is relevant for the diagnosis of azoospermia in men with spinal cord injuries. Spinal Cord. 2011;49:55–9.PubMed Iremashvili V, Brackett NL, Ibrahim E, Aballa TC, Lynne CM. The choice of assisted ejaculation method is relevant for the diagnosis of azoospermia in men with spinal cord injuries. Spinal Cord. 2011;49:55–9.PubMed
140.
Zurück zum Zitat Ekland MB, Krassioukov AV, McBride KE, Elliott SL. Incidence of autonomic dysreflexia and silent autonomic dysreflexia in men with spinal cord injury undergoing sperm retrieval: implications for clinical practice. J Spinal Cord Med. 2008;31:33–9.PubMedPubMedCentral Ekland MB, Krassioukov AV, McBride KE, Elliott SL. Incidence of autonomic dysreflexia and silent autonomic dysreflexia in men with spinal cord injury undergoing sperm retrieval: implications for clinical practice. J Spinal Cord Med. 2008;31:33–9.PubMedPubMedCentral
141.
Zurück zum Zitat Wieder JA, Lynne CM, Ferrell SM, Aballa TC, Brackett NL. Brown-colored semen in men with spinal cord injury. J Androl. 1999;20:594–600.PubMed Wieder JA, Lynne CM, Ferrell SM, Aballa TC, Brackett NL. Brown-colored semen in men with spinal cord injury. J Androl. 1999;20:594–600.PubMed
142.
Zurück zum Zitat Utida C, Truzzi JC, Bruschini H, Simonetti R, Cedenho AP, Srougi M, et al. Male infertility in spinal cord trauma. Int Braz J Urol. 2005;31:375–83.PubMed Utida C, Truzzi JC, Bruschini H, Simonetti R, Cedenho AP, Srougi M, et al. Male infertility in spinal cord trauma. Int Braz J Urol. 2005;31:375–83.PubMed
143.
Zurück zum Zitat Momen MN, Fahmy I, Amer M, Arafa M, Zohdy W, Naser TA. Semen parameters in men with spinal cord injury: changes and aetiology. Asian J Androl. 2007;9:684–9.PubMed Momen MN, Fahmy I, Amer M, Arafa M, Zohdy W, Naser TA. Semen parameters in men with spinal cord injury: changes and aetiology. Asian J Androl. 2007;9:684–9.PubMed
144.
Zurück zum Zitat Qiu Y, Wang LG, Zhang LH. Quality of sperm obtained by penile vibratory stimulation and percutaneous vasal sperm aspiration in men with spinal cord injury. J Androl. 2012;33(5):1036–46.PubMed Qiu Y, Wang LG, Zhang LH. Quality of sperm obtained by penile vibratory stimulation and percutaneous vasal sperm aspiration in men with spinal cord injury. J Androl. 2012;33(5):1036–46.PubMed
145.
Zurück zum Zitat Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL. Infammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J Androl. 2004;25(2):250–4.PubMed Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL. Infammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries. J Androl. 2004;25(2):250–4.PubMed
146.
Zurück zum Zitat Brackett NL, Cohen DR, Ibrahim E, Aballa TC, Lynne CM. Neutralization of cytokine activity at the receptor level improves sperm motility in men with spinal cord injuries. J Androl. 2007;28(5):717–21.PubMed Brackett NL, Cohen DR, Ibrahim E, Aballa TC, Lynne CM. Neutralization of cytokine activity at the receptor level improves sperm motility in men with spinal cord injuries. J Androl. 2007;28(5):717–21.PubMed
147.
Zurück zum Zitat Durga A, Sepahpanah F, Regozzi M, Hastings J, Crane DA. Prevalence of testosterone deficiency after spinal cord injury. PM R. 2011;3:929–32.PubMed Durga A, Sepahpanah F, Regozzi M, Hastings J, Crane DA. Prevalence of testosterone deficiency after spinal cord injury. PM R. 2011;3:929–32.PubMed
148.
Zurück zum Zitat • Sinha V, Elliott S, Ibrahim E, et al. Reproductive health of men with spinal cord injury. Top Spinal Cord Inj Rehabil. 2017;23:31–41 This article addresses conditions, such as hypogonadism, that should be taken into account when managing the reproductive health of men with SCI.PubMedPubMedCentral • Sinha V, Elliott S, Ibrahim E, et al. Reproductive health of men with spinal cord injury. Top Spinal Cord Inj Rehabil. 2017;23:31–41 This article addresses conditions, such as hypogonadism, that should be taken into account when managing the reproductive health of men with SCI.PubMedPubMedCentral
149.
Zurück zum Zitat Sullivan SD, Nash MS, Tefera E, Tinsley E, Blackman MR, Groah S. Prevalence and etiology of hypogonadism in young men with chronic spinal cord injury: a cross-sectional analysis from two university-based rehabilitation centers. PM R. 2017;9:751–60.PubMed Sullivan SD, Nash MS, Tefera E, Tinsley E, Blackman MR, Groah S. Prevalence and etiology of hypogonadism in young men with chronic spinal cord injury: a cross-sectional analysis from two university-based rehabilitation centers. PM R. 2017;9:751–60.PubMed
150.
Zurück zum Zitat Bauman WA, La Fountaine MF, Cirnigliaro CM, et al. Testicular responses to hCG stimulation at varying doses in men with spinal cord injury. Spinal Cord. 2017;55:659–63.PubMedPubMedCentral Bauman WA, La Fountaine MF, Cirnigliaro CM, et al. Testicular responses to hCG stimulation at varying doses in men with spinal cord injury. Spinal Cord. 2017;55:659–63.PubMedPubMedCentral
151.
Zurück zum Zitat Naderi AR, Safarinejad MR. Endocrine profiles and semen quality in spinal cord injured men. Clin Endocrinol. 2003;58:177–84. Naderi AR, Safarinejad MR. Endocrine profiles and semen quality in spinal cord injured men. Clin Endocrinol. 2003;58:177–84.
152.
Zurück zum Zitat Reilly JM, Oates RD. Preliminary investigation of the potential fertility status of postpubertal males with myelodysplasia. J Urol. 1992;151:114–9. Reilly JM, Oates RD. Preliminary investigation of the potential fertility status of postpubertal males with myelodysplasia. J Urol. 1992;151:114–9.
153.
Zurück zum Zitat Kolon TF, Herndon CD, Baker LA, Baskin LS, Baxter CG, Cheng EY, et al. Evaluation and treatment of cryptorchidism: AUA guideline. J Urol. 2014;192:337–45.PubMed Kolon TF, Herndon CD, Baker LA, Baskin LS, Baxter CG, Cheng EY, et al. Evaluation and treatment of cryptorchidism: AUA guideline. J Urol. 2014;192:337–45.PubMed
154.
Zurück zum Zitat Kropp KA, Voeller KK. Cryptorchidism in meningomyelocele. J Pediatr. 1981;99:110–3.PubMed Kropp KA, Voeller KK. Cryptorchidism in meningomyelocele. J Pediatr. 1981;99:110–3.PubMed
155.
Zurück zum Zitat Hutson JM, Beasley SW, Bryan AD. Cryptorchidism in spina bifida and spinal cord transection: a clue to the mechanism of transinguinal descent of the testis. J Pediatr Surg. 1988;23:275–7.PubMed Hutson JM, Beasley SW, Bryan AD. Cryptorchidism in spina bifida and spinal cord transection: a clue to the mechanism of transinguinal descent of the testis. J Pediatr Surg. 1988;23:275–7.PubMed
156.
Zurück zum Zitat Ferrara P, Rossodivita A, Ruggiero A, et al. Cryptorchidism associated with meningomyelocele. J Paediatr Child Health. 1998;34:44–6.PubMed Ferrara P, Rossodivita A, Ruggiero A, et al. Cryptorchidism associated with meningomyelocele. J Paediatr Child Health. 1998;34:44–6.PubMed
157.
Zurück zum Zitat Patel RP, Kolon TF, Huff DS, Carr MC, Zderic SA, Canning DA, et al. Cryptorchid testis histopathology in myelomeningocele patients. J Pediatr Urol. 2008;4:434–7.PubMed Patel RP, Kolon TF, Huff DS, Carr MC, Zderic SA, Canning DA, et al. Cryptorchid testis histopathology in myelomeningocele patients. J Pediatr Urol. 2008;4:434–7.PubMed
158.
Zurück zum Zitat Berezin M, Ohry H, Shemesh Y, et al. Hyperprolactinemia, galactorrhea and amenorrhea in women with spinal cord injury. Gynecol Endocrinol. 1989;3:159–16.PubMed Berezin M, Ohry H, Shemesh Y, et al. Hyperprolactinemia, galactorrhea and amenorrhea in women with spinal cord injury. Gynecol Endocrinol. 1989;3:159–16.PubMed
159.
Zurück zum Zitat Boyd AE, Spare S, Bower B, Reichlin S. Neurogenic galactorrhea amenorrhea. J Clin Endocrinol Metab. 1978;47:1374–7.PubMed Boyd AE, Spare S, Bower B, Reichlin S. Neurogenic galactorrhea amenorrhea. J Clin Endocrinol Metab. 1978;47:1374–7.PubMed
160.
Zurück zum Zitat Jackson AB. Hyperprolactinemia following SCI. San Diego: Presented at the 18th Annual Scientific Meeting of the American Spinal Cord Injury Association; 1992. Jackson AB. Hyperprolactinemia following SCI. San Diego: Presented at the 18th Annual Scientific Meeting of the American Spinal Cord Injury Association; 1992.
161.
Zurück zum Zitat Charlifue SW, Gerhart KA, Menter RR, Whiteneck GG, Manley MS. Sexual issues of women with spinal cord injuries. Paraplegia. 1992;30(3):192–9.PubMed Charlifue SW, Gerhart KA, Menter RR, Whiteneck GG, Manley MS. Sexual issues of women with spinal cord injuries. Paraplegia. 1992;30(3):192–9.PubMed
162.
Zurück zum Zitat Kiekens C. Pregnancy in spinal cord injury. In: Corcos J, Ginsberg D, Karsenty G, editors. Textbook of the neurogenic bladder. 3rd ed. Boca Raton: CRC Press; 2015. Kiekens C. Pregnancy in spinal cord injury. In: Corcos J, Ginsberg D, Karsenty G, editors. Textbook of the neurogenic bladder. 3rd ed. Boca Raton: CRC Press; 2015.
163.
Zurück zum Zitat DeForge D, Blackmer J, Garritty C, Yazdi F, Cronin V, Barrowman N, et al. Fertility following spinal cord injury: a systematic review. Spinal Cord. 2005;43:693–703.PubMed DeForge D, Blackmer J, Garritty C, Yazdi F, Cronin V, Barrowman N, et al. Fertility following spinal cord injury: a systematic review. Spinal Cord. 2005;43:693–703.PubMed
164.
Zurück zum Zitat Nehra A, Werner MA, Bastuba M, Title C, Oates RD*. Vibratory stimulation and rectal probe electroejaculation as therapy for patients with spinal cord injury: semen parameters and pregnancy rates. J Urol. 1996;155:554–9.PubMed Nehra A, Werner MA, Bastuba M, Title C, Oates RD*. Vibratory stimulation and rectal probe electroejaculation as therapy for patients with spinal cord injury: semen parameters and pregnancy rates. J Urol. 1996;155:554–9.PubMed
165.
Zurück zum Zitat Kathiresan ASQ, Ibrahim E, Aballa TC, Attia GR, Ory SJ, Hoffman DI, et al. Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries. Fertil Steril. 2011;96:562–6.PubMed Kathiresan ASQ, Ibrahim E, Aballa TC, Attia GR, Ory SJ, Hoffman DI, et al. Comparison of in vitro fertilization/intracytoplasmic sperm injection outcomes in male factor infertility patients with and without spinal cord injuries. Fertil Steril. 2011;96:562–6.PubMed
166.
Zurück zum Zitat Iezzoni LI, Chen Y, McLain AB. Current pregnancy among women with spinal cord injury: finding from the US National Spinal Cord Injury Database. Spinal Cord. 2015;53(11):821–6.PubMedPubMedCentral Iezzoni LI, Chen Y, McLain AB. Current pregnancy among women with spinal cord injury: finding from the US National Spinal Cord Injury Database. Spinal Cord. 2015;53(11):821–6.PubMedPubMedCentral
167.
Zurück zum Zitat Consortium for Spinal Cord M. Sexuality and reproductive health in adults with spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med. 2010;33(3):281–336. Consortium for Spinal Cord M. Sexuality and reproductive health in adults with spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med. 2010;33(3):281–336.
168.
Zurück zum Zitat • Shepard CL, Yan PL, Hollingsworth JM, Kraft KH. Pregnancy among mothers with spina bifida. J Pediatr Urol. 2018;14(1):11.e1–6 This study describes the importance of pediatric and transitional urologists initiating discussion on sexual and reproductive health in early adolescence in Spina Bifida patients. • Shepard CL, Yan PL, Hollingsworth JM, Kraft KH. Pregnancy among mothers with spina bifida. J Pediatr Urol. 2018;14(1):11.e1–6 This study describes the importance of pediatric and transitional urologists initiating discussion on sexual and reproductive health in early adolescence in Spina Bifida patients.
169.
Zurück zum Zitat Vordermark JS, Deshon GE, Agee RE. Management of pregnancy after major urinary reconstruction. Obstet Gynecol. 1990;75(3 Pt 2):564e7. Vordermark JS, Deshon GE, Agee RE. Management of pregnancy after major urinary reconstruction. Obstet Gynecol. 1990;75(3 Pt 2):564e7.
Metadaten
Titel
Sexual Health in the Neurogenic Patient
verfasst von
Kirk D. Redger
Alan Quach
Brian J. Flynn
Publikationsdatum
09.12.2020
Verlag
Springer US
Erschienen in
Current Bladder Dysfunction Reports / Ausgabe 4/2020
Print ISSN: 1931-7212
Elektronische ISSN: 1931-7220
DOI
https://doi.org/10.1007/s11884-020-00605-0

Weitere Artikel der Ausgabe 4/2020

Current Bladder Dysfunction Reports 4/2020 Zur Ausgabe

Global Health (Kurt McCammon, Section Editor)

Cost-Effectiveness and Economic Benefits of Volunteerism

Overactive Bladder (U Lee and S Adelstein, Section Editors)

Contemporary Landmark Trials Update in the Management of Idiopathic Overactive Bladder

Overactive Bladder (U Lee and S Adelstein, Section Editors)

Treatment of Overactive Bladder in the Frail Patient

Inflammatory/Infectious Bladder Disorders (MS Mourad, Section Editor)

Vaginal Yeast Infection

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

Stufenschema weist Prostatakarzinom zuverlässig nach

22.04.2024 Prostatakarzinom Nachrichten

Erst PSA-Test, dann Kallikrein-Score, schließlich MRT und Biopsie – ein vierstufiges Screening-Schema kann die Zahl der unnötigen Prostatabiopsien erheblich reduzieren: Die Hälfte der Männer, die in einer finnischen Studie eine Biopsie benötigten, hatte einen hochgradigen Tumor.

Harnwegsinfektprophylaxe: Es geht auch ohne Antibiotika

20.04.2024 EAU 2024 Kongressbericht

Beim chronischen Harnwegsinfekt bei Frauen wird bisher meist eine Antibiotikaprophylaxe eingesetzt. Angesichts der zunehmenden Antibiotikaresistenz erweist sich das Antiseptikum Methenamin-Hippurat als vielversprechende Alternative, so die Auswertung einer randomisierten kontrollierten Studie.

Update Urologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.