Background
Method
Results
Melancholia CORE 0 to 10 (N = 18) | Melancholia CORE 15 to 31 (N = 14) | Psychotic CORE 13 to 37 (n = 32) | |
---|---|---|---|
Sex ratio
|
14 F : 4 M
|
9 F : 5 M
|
18 F : 14 M
|
Age (mean)
|
74.7 years
|
77.4 years
|
75.0 years
|
Age range
|
69–85 years
|
67–91 years
|
65–87 years
|
Age of onset (mean)
|
49.8 years
|
65.4 years
|
56.2 years
|
Onset age 65+
|
41%
|
79%
|
53%
|
Duration (mean)
|
35 weeks
|
49 weeks
|
>50 weeks
|
Hamilton-17 (mean)
|
25.9
|
29.1
|
27.8
|
BAS (mean)
|
17.2
|
18.6
|
17.4*
|
MMSE
|
26.6
|
26.9
|
26.7*
|
Had depression previously
|
89%
|
64%
|
77%
|
Had antidepressants before
|
78%
|
64%
|
77%
|
Had E.C.T. previously
|
67%
|
50%
|
68%
|
Stress as precipitant
|
89%
+
|
57%
|
52%
|
Diurnal variation (worse in a.m.: moderate/severe)
|
61%
+
|
36%
|
10%
|
Unvarying depression
|
22%
+
|
79%
|
100%
|
Worthlessness
|
61% + (4/10 with score <8; 7/8 with score 8–10)
|
86%
|
74%
|
Punishment felt to be deserved
|
0%
|
29%
(4/14)
|
52%
|
CORE score | Number of DSM-IV melancholia criteria fulfilled | Feelings of being slowed | Hamilton rating of retardation | Hamilton rating of agitation | |
---|---|---|---|---|---|
F 80
|
0
|
8
|
Yes
|
0
|
0
|
F 71
|
1
|
5
|
Yes
|
0
|
0
|
F 83
|
1
|
5
|
Yes
|
0
|
1
|
F 74
|
2
|
7
|
Yes
|
0
|
0
|
F 68
|
4
|
6
|
Unsure
|
1
|
0
|
M 75
|
5
|
6
|
Unrecorded
|
1
|
0
|
F 82
|
6
|
7
|
Yes
|
1
|
1
|
M 77
|
6
|
5
|
Yes
|
0
|
0
|
F 79
|
6
|
6
|
Unsure
|
1
|
1
|
F 69
|
7
|
5
|
Yes
|
0
|
0
|
M 67
|
8
|
8
|
Yes
|
0
|
0
|
F 69
|
8
|
6
|
Yes
|
1
|
0
|
F 76
|
8
|
8
|
Yes
|
1
|
1
|
F 70
|
8
|
7
|
Yes
|
2
|
0
|
F 77
|
9
|
6
|
Yes
|
2
|
1
|
F 78
|
9
|
6
|
Yes
|
1
|
0
|
F 73
|
10
|
7
|
Yes
|
1
|
3
|
M 84
|
10
|
6
|
Yes
|
1
|
0
|