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Comparative Clinical Pathology

Erschienen in:

01.01.2016 | Original Article

Silver nanoparticles affects the expression of biomarker genes mRNA in rainbow trout (Oncorhynchus mykiss)

verfasst von: Seyed Ali Johari, Mohammad Reza Kalbassi, Sang Bum Lee, Mi Sook Dong, Il Je Yu

Erschienen in: Comparative Clinical Pathology | Ausgabe 1/2016

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Abstract

Due to their strong antiseptic properties, silver nanoparticles (AgNPs) are widely used in consumer products, and therefore there is a high risk of their release to the aquatic environment. In the present study, we investigated chronic effect of waterborne AgNPs on the mRNA expression of four important biomarker genes including metallothionein (MT), glutathione S-transferase (GST), superoxide dismutase (SOD), and glutathione peroxidase (GPX) in the gill tissue of rainbow trout. Twenty-one-day exposure to AgNPs significantly increased MT and GST mRNA levels in the gills in a dose-dependent manner. Although mRNA levels of SOD significantly increased in the gills of fish exposed to AgNPs, but its increase was not dose-dependent. In contrast, exposure to AgNPs significantly decreased GPX mRNA levels in the gills. The results suggest that exposure to AgNPs can significantly change the expression of biomarker genes mRNA in rainbow trout.

Asghari S, Johari SA, Lee JH, Kim YS, Jeon YB, Choi HJ, Moon MC, Yu IJ (2012) Toxicity of various silver nanoparticles compared to silver ions in Daphnia magna. J Nanobiotechnology 10:14CrossRefPubMedPubMedCentral

Basha PS, Rani AU (2003) Cadmium-induced antioxidant defense mechanism in freshwater teleost Oreochromis mossambicus (Tilapia). Ecotoxicol Environ Saf 56:218–221CrossRefPubMed

Batley GE, Kirby JK, McLaughlin MJ (2013) Fate and risks of nanomaterials in aquatic and terrestrial environments. Acc Chem Res 46:854–862CrossRefPubMed

Carlson C, Hussain SM, Schrand AM, Braydich-Stolle LK, Hess KL, Jones RL, Schlager JJ (2008) Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J Phys Chem B 112(43):13608–13619CrossRefPubMed

Chae YJ, Pham CH, Lee J, Bae E, Yi J, Gu MB (2009) Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryzias latipes). Aquat Toxicol 94:320–327CrossRefPubMed

Choi O, Hu Z (2008) Size dependent and reactive oxygen species related nanosilver toxicity to nitrifying bacteria. Environ Sci Technol 42(12):4583–4588CrossRefPubMed

Choi CY, An KW, Nelson ER, Habibi HR (2007) Cadmium affects the expression of metallothionein (MT) and glutathione peroxidase (GPX) mRNA in goldfish, Carassius auratus. Comp Biochem Physiol, Part C 145:595–600

Choi JE, Kim S, Ahn JH, Youn P, Kang JS, Park K, Yi J, Ryu DY (2010) Induction of oxidative stress and apoptosis by silver nanoparticles in the liver of adult zebrafish. Aquat Toxicol 100(2):151–159CrossRefPubMed

Crago J, Corsi SR, Weber D, Bannerman R, Klaper R (2011) Linking biomarkers to reproductive success of caged fathead minnows in streams with increasing urbanization. Chemosphere 82:1669–1674CrossRefPubMed

Farmen E, Mikkelsen HN, Evensen Ø, Einset J, Heier LS, Rosseland BO, Salbu B, Tollefsen KE, Oughton DH (2012) Acute and sub-lethal effects in juvenile Atlantic salmon exposed to low μg/L concentrations of Ag nanoparticles. Aquat Toxicol 108:78–84CrossRefPubMed

Foldbjerg R, Olesen P, Hougaard M, Dang DA, Hoffmann HJ, Autrup H (2009) PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes. Toxicol Lett 190(2):156–162CrossRefPubMed

Fu PP, Xia Q, Hwang HM, Ray PC, Yu H (2014) Mechanisms of nanotoxicity: generation of reactive oxygen species. J Food Drug Anal 22(1):64–75CrossRefPubMed

Gagné F, Auclair J, Fortier M, Bruneau A, Fournier M, Turcotte P, Pilote M, Gagnon C (2013) Bioavailability and immunotoxicity of silver nanoparticles to the freshwater mussel Elliptio complanata. J Toxic Environ Health A 76(13):767–777CrossRef

Giovanni M, Tay CY, Setyawati MI, Xie J, Ong CN, Fan R, Yue J, Zhang L, Leong DT (2014) Toxicity profiling of water contextual zinc oxide, silver, and titanium dioxide nanoparticles in human oral and gastrointestinal cell systems. Environ Toxicol. doi:10.1002/tox.22015 PubMed

Hermesz E, Abrahám M, Nemcsók J (2001) Tissue-specific expression of two metallothionein genes in common carp during cadmium exposure and temperature shock. Comp Biochem Physiol Part C 128:457–465

Johari SA, Kalbassi MR, Soltani M, Yu IJ (2013) Toxicity comparison of colloidal silver nanoparticles in various life stages of rainbow trout (Oncorhynchus mykiss). Iran J Fish Sci 12(1):76–95

Johari SA, Kalbassi MR, Yu IJ, Lee JH (2014a) Chronic effect of waterborne silver nanoparticles on rainbow trout (Oncorhynchus mykiss): histopathology and bioaccumulation. Comp Clin Pathol. doi:10.1007/s00580-014-2019-2

Johari SA, Sourinejad I, Bärsch N, Saed-Moocheshi S, Kaseb A, Nazdar N (2014b) Does physical production of nanoparticles reduce their ecotoxicity? A case of lower toxicity of AgNPs produced by laser ablation to zebrafish (Danio rerio). Int J Aquat Biol 2(4):188–192

Johari SA, Habibi L, Hosseini SJ (2014c) Toxicity of colloidal nano-silver to zebrafish, Danio rerio: ions, nanoparticles, or both? J Aquat Nutr Biochem 1(1):59–68

Johari SA, Kalbassi MR, Sltani M, Yu IJ (2015) Application of nanosilver-coated zeolite as water filter media for fungal disinfection of rainbow trout (Oncorhynchus mykiss) eggs. Aquac Int. doi:10.1007/s10499-015-9906-7

Keller AA, McFerran S, Lazareva A, Suh S (2013) Global life cycle releases of engineered nanomaterials. J Nanoparticle Res 15:1692CrossRef

Lange A, Ausseil O, Segner H (2002) Alterations of tissue glutathione levels and metallothionein mRNA in rainbow trout during single and combined exposure to cadmium and zinc. Comp Biochemi Physiol Part C 131:231–243

Li H, Turner A, Brown MT (2012) Accumulation of aqueous and nanoparticulate silver by the marine gastropod Littorina littorea. Water Air Soil Pollut 224:1354CrossRef

Ng KW, Khoo SP, Heng BC, Setyawati MI, Tan EC, Zhao X, Xiong S, Fang W, Leong DT, Loo JS (2011) The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles. Biomaterials 32(32):8218–8225CrossRefPubMed

Nickum JG, Bart HL Jr, Bowser PR, Greer IE, Hubbs C, Jenkins JA, MacMillan JR, Rachlin JW, Rose JD, Sorensen PW, Tomasso JR (2004) Guidelines for the use of fishes in research. American Fisheries Society, Bethesda, p 54

OECD (1984) OECD guidelines for the testing of chemicals. Test No. 204: fish, prolonged toxicity test: 14-day study. Organization for Economic Cooperation and Development, Paris

Oukarroum A, Samadani M, Dewez D (2014) Influence of pH on the toxicity of silver nanoparticles in the green alga Chlamydomonas acidophila. Water Air Soil Pollut 225:2038CrossRef

Pham CH, Yi J, Gu MB (2012) Biomarker gene response in male Medaka (Oryzias latipes) chronically exposed to silver nanoparticle. Ecotoxicol Environ Saf 78:239–245CrossRefPubMed

Ribeiro F, Gallego-Urrea JA, Jurkschat K, Crossley A, Hassellöv M, Taylor C, Soares AM, Loureiro S (2014) Silver nanoparticles and silver nitrate induce high toxicity to Pseudokirchneriella subcapitata, Daphnia magna and Danio rerio. Sci Total Environ 466–467:232–241CrossRefPubMed

Roberts AP, Oris JT (2004) Multiple biomarker response in rainbow trout during exposure to hexavalent chromium. Comp Biochem Physiol, Part C 138:221–228

Roesijadi G (1992) Metallothioneins in metal regulation and toxicity in aquatic animals. Aquat Toxicol 22:81–114CrossRef

Roesijadi G (1996) Metallothionein and its role in toxic metal regulation. Comp Biochem Physiol, Part C 113(2):117–123

Salari Joo H, Kalbassi MR, Yu IJ, Lee JH, Johari SA (2013) Bioaccumulation of silver nanoparticles in rainbow trout (Oncorhynchus mykiss): influence of concentration and salinity. Aquat Toxicol 140–141:398–406CrossRefPubMed

Scown TM, Santos EM, Johnston BD, Gaiser B, Baalousha M, Mitov S, Lead JR, Stone V, Fernandes TF, Jepson M, van Aerle R, Tyler CR (2010) Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout. Toxicol Sci 115(2):521–534CrossRefPubMed

Setyawati MI, Tay CY, Leong DT (2013) Effect of zinc oxide nanomaterials-induced oxidative stress on the p53 pathway. Biomaterials 34(38):10133–10142CrossRefPubMed

Setyawati MI, Yuan X, Xie J, Leong DT (2014) The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells. Biomaterials 35(25):6707–6715CrossRefPubMed

Sohn EK, Johari SA, Kim TG, Kim JK, Kim E, Lee JH, Chung YS, Yu IJ (2015) Aquatic toxicity comparison of silver nanoparticles and silver nanowires. BioMed Res Int. doi:10.1155/2015/893049

Tay CY, Setyawati MI, Xie J, Parak WJ, Leong DT (2014) Back to basics: exploiting the innate physico-chemical characteristics of nanomaterials for biomedical applications. Adv Funct Mater 24(38):5936–5955CrossRef

van Heerden D, Vosloo A, Nikinmaa M (2004) Effects of short-term copper exposure on gill structure, metallothionein and hypoxia-inducible factor-1alpha (HIF-1alpha) levels in rainbow trout (Oncorhynchus mykiss). Aquat Toxicol 69:271–280CrossRefPubMed

Welsh PG, Lipton J, Mebane CA, Marr JCA (2008) Influence of flow-through and renewal exposures on the toxicity of copper to rainbow trout. Ecotoxicol Environ Saf 69:199–208CrossRefPubMed

Woodrow Wilson Database (2013) Nanotechnology consumer product inventory. http://www.nanotechproject.org/cpi/about/analysis/. Accessed at 10 June 2015

Xia T, Zhao Y, Sager T, George S, Pokhrel S, Li N, Schoenfeld D, Meng H, Lin S, Wang X, Wang M, Ji Z, Zink JI, Mädler L, Castranova V, Lin S, Nel AE (2011) Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. ACS Nano 5(2):1223–1235CrossRefPubMedPubMedCentral

Titel: Silver nanoparticles affects the expression of biomarker genes mRNA in rainbow trout (Oncorhynchus mykiss)
verfasst von: Seyed Ali Johari
Mohammad Reza Kalbassi
Sang Bum Lee
Mi Sook Dong
Il Je Yu
Publikationsdatum: 01.01.2016
Verlag: Springer London
Erschienen in: Comparative Clinical Pathology / Ausgabe 1/2016
Print ISSN: 1618-5641
Elektronische ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-015-2144-6

Springer Medizin

Silver nanoparticles affects the expression of biomarker genes mRNA in rainbow trout (Oncorhynchus mykiss)

Abstract

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Vergleichende Pathologie in der onkologischen Forschung

Gastrointestinale Stromatumoren

Personalisierte Medizin in der Onkologie

Springer Medizin

Abstract

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