Skip to main content
Erschienen in: International Journal of Behavioral Medicine 5/2018

29.08.2018

Sleep Quality in Ulcerative Colitis: Associations with Inflammation, Psychological Distress, and Quality of Life

Erschienen in: International Journal of Behavioral Medicine | Ausgabe 5/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Treatment of ulcerative colitis (UC), given its chronicity and its associated disruptive and often distressing symptoms, is increasingly focusing on maximizing patient quality of life. Poorer quality of life has been found among patients with poor sleep quality, which is much more common in patients with UC than in the general population and may be associated with inflammation and psychological distress.

Method

Forty-seven patients with UC (n = 11 flaring) completed measures of sleep quality, depression, state anxiety, gastrointestinal-related anxiety, perceived stress, and quality of life. Measures of inflammation were also obtained.

Results

Patients endorsed high rates of poor sleep quality, which was highly correlated with depression and poorer inflammatory bowel disease-related quality of life, but was generally not related to other areas of psychological functioning or inflammation. Sleep quality was significantly independently associated with depression and female gender.

Conclusion

Poor sleep quality is prevalent in patients with UC and is strongly related to depression, suggesting that sleep and mood are important areas to assess in patients with UC in order to inform tailored treatment to improve quality of life.
Literatur
1.
Zurück zum Zitat Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A. Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol. 2007;22(11):1748–53.CrossRefPubMed Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A. Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol. 2007;22(11):1748–53.CrossRefPubMed
2.
Zurück zum Zitat Parekh PJ, Oldfield Iv EC, Challapallisri V, Ware JC, Johnson DA. Sleep disorders and inflammatory disease activity: chicken or the egg? Am J Gastroenterol. 2015;110(4):484–8.CrossRefPubMed Parekh PJ, Oldfield Iv EC, Challapallisri V, Ware JC, Johnson DA. Sleep disorders and inflammatory disease activity: chicken or the egg? Am J Gastroenterol. 2015;110(4):484–8.CrossRefPubMed
3.
Zurück zum Zitat Ranjbaran Z, Keefer L, Stepanski E, Farhadi A, Keshavarzian A. The relevance of sleep abnormalities to chronic inflammatory conditions. Inflamm Res. 2007;56(2):51–7.CrossRefPubMed Ranjbaran Z, Keefer L, Stepanski E, Farhadi A, Keshavarzian A. The relevance of sleep abnormalities to chronic inflammatory conditions. Inflamm Res. 2007;56(2):51–7.CrossRefPubMed
4.
Zurück zum Zitat Graff LA, Vincent N, Walker JR, Clara I, Carr R, Ediger J, et al. A population-based study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis. 2011;17(9):1882–9.CrossRefPubMed Graff LA, Vincent N, Walker JR, Clara I, Carr R, Ediger J, et al. A population-based study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis. 2011;17(9):1882–9.CrossRefPubMed
5.
Zurück zum Zitat Zeitlhofer J, Schmeiser-Rieder A, Tribl G, Rosenberger A, Bolitschek J, Kapfhammer G, et al. Sleep and quality of life in the Austrian population. Acta Neurol Scand. 2000;102(4):249–57.CrossRefPubMed Zeitlhofer J, Schmeiser-Rieder A, Tribl G, Rosenberger A, Bolitschek J, Kapfhammer G, et al. Sleep and quality of life in the Austrian population. Acta Neurol Scand. 2000;102(4):249–57.CrossRefPubMed
6.
Zurück zum Zitat Ali T, Madhoun MF, Orr WC, Rubin DT. Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients. Inflamm Bowel Dis. 2013;19(11):2440–3.CrossRefPubMed Ali T, Madhoun MF, Orr WC, Rubin DT. Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients. Inflamm Bowel Dis. 2013;19(11):2440–3.CrossRefPubMed
7.
Zurück zum Zitat Gingold-Belfer R, Peled N, Levy S, Katz N, Niv Y, Fass R, et al. Impaired sleep quality in Crohn’s disease depends on disease activity. Dig Dis Sci. 2014;59(1):146–51.CrossRefPubMed Gingold-Belfer R, Peled N, Levy S, Katz N, Niv Y, Fass R, et al. Impaired sleep quality in Crohn’s disease depends on disease activity. Dig Dis Sci. 2014;59(1):146–51.CrossRefPubMed
8.
Zurück zum Zitat Addolorato G, Capristo E, Stefanini GF, Gasbarrini G. Inflammatory bowel disease: a study of the association between anxiety and depression, physical morbidity, and nutritional status. Scand J Gastroenterol. 1997;32(10):1013–21.CrossRefPubMed Addolorato G, Capristo E, Stefanini GF, Gasbarrini G. Inflammatory bowel disease: a study of the association between anxiety and depression, physical morbidity, and nutritional status. Scand J Gastroenterol. 1997;32(10):1013–21.CrossRefPubMed
9.
Zurück zum Zitat Morys JM, Kaczówka A, Jeżewska M. Assessment of selected psychological factors in patients with inflammatory bowel disease. Prz Gastroenterol. 2016;11(1):47–53.CrossRefPubMed Morys JM, Kaczówka A, Jeżewska M. Assessment of selected psychological factors in patients with inflammatory bowel disease. Prz Gastroenterol. 2016;11(1):47–53.CrossRefPubMed
10.
Zurück zum Zitat Bao YP, Han Y, Ma J, Wang RJ, Shi L, Wang TY, et al. Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: meta-analysis and systematic review. Neurosci Biobehav Rev. 2017;75:257–73.CrossRefPubMed Bao YP, Han Y, Ma J, Wang RJ, Shi L, Wang TY, et al. Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: meta-analysis and systematic review. Neurosci Biobehav Rev. 2017;75:257–73.CrossRefPubMed
11.
Zurück zum Zitat Meerlo P, Havekes R, Steiger A. Chronically restricted or disrupted sleep as a causal factor in the development of depression. Curr Top Behav Neurosci. 2015;25:459–81.CrossRefPubMed Meerlo P, Havekes R, Steiger A. Chronically restricted or disrupted sleep as a causal factor in the development of depression. Curr Top Behav Neurosci. 2015;25:459–81.CrossRefPubMed
12.
Zurück zum Zitat Menefee LA, Frank ED, Doghramji K, Picarello K, Park JJ, Jalali S, et al. Self-reported sleep quality and quality of life for individuals with chronic pain conditions. Clin J Pain. 2000;16(4):290–7.CrossRefPubMed Menefee LA, Frank ED, Doghramji K, Picarello K, Park JJ, Jalali S, et al. Self-reported sleep quality and quality of life for individuals with chronic pain conditions. Clin J Pain. 2000;16(4):290–7.CrossRefPubMed
13.
Zurück zum Zitat Blom K, Jernelöv S, Kraepelien M, Bergdahl MO, Jungmarker K, Ankartjärn L, et al. Internet treatment addressing either insomnia or depression, for patients with both diagnoses: a randomized trial. Sleep. 2015;38(2):267–77.CrossRefPubMedPubMedCentral Blom K, Jernelöv S, Kraepelien M, Bergdahl MO, Jungmarker K, Ankartjärn L, et al. Internet treatment addressing either insomnia or depression, for patients with both diagnoses: a randomized trial. Sleep. 2015;38(2):267–77.CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Guyatt G, Mitchell A, Irvine EJ, Singer J, Williams N, Goodacre R, et al. A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology. 1989;96(3):804–10.CrossRefPubMed Guyatt G, Mitchell A, Irvine EJ, Singer J, Williams N, Goodacre R, et al. A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology. 1989;96(3):804–10.CrossRefPubMed
15.
Zurück zum Zitat Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987;317(26):1625–9.CrossRefPubMed Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987;317(26):1625–9.CrossRefPubMed
16.
Zurück zum Zitat Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213.CrossRefPubMed Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989;28(2):193–213.CrossRefPubMed
17.
Zurück zum Zitat Beck AT, Steer RA, GK B. Manual for the Beck Depression Inventory—II. San Antonio, TX: Psychological Corporation; 1996. Beck AT, Steer RA, GK B. Manual for the Beck Depression Inventory—II. San Antonio, TX: Psychological Corporation; 1996.
18.
Zurück zum Zitat Whisman MA, Perez JE, Ramel W. Factor structure of the Beck Depression Inventory—second edition (BDI-II) in a student sample. J Clin Psychol. 2000;56(4):545–51.CrossRefPubMed Whisman MA, Perez JE, Ramel W. Factor structure of the Beck Depression Inventory—second edition (BDI-II) in a student sample. J Clin Psychol. 2000;56(4):545–51.CrossRefPubMed
19.
Zurück zum Zitat Spielberger CD. Manual for the State-Trait Anxiety Inventory STAI. Palo Alto, CA: Consulting Psychologists Press; 1983. Spielberger CD. Manual for the State-Trait Anxiety Inventory STAI. Palo Alto, CA: Consulting Psychologists Press; 1983.
20.
Zurück zum Zitat Labus J, Bolus R, Chang L, et al. The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. Aliment Pharmacol Ther. 2004;20:89–97.CrossRefPubMed Labus J, Bolus R, Chang L, et al. The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. Aliment Pharmacol Ther. 2004;20:89–97.CrossRefPubMed
21.
Zurück zum Zitat Levenstein S, Prantera C, Varvo V, Scribano ML, Berto E, Luzi C, et al. Development of the Perceived Stress Questionnaire: a new tool for psychosomatic research. J Psychosom Res. 1993;37(1):19–32.CrossRefPubMed Levenstein S, Prantera C, Varvo V, Scribano ML, Berto E, Luzi C, et al. Development of the Perceived Stress Questionnaire: a new tool for psychosomatic research. J Psychosom Res. 1993;37(1):19–32.CrossRefPubMed
22.
Zurück zum Zitat Powell-Tuck J, Day DW, Bucknell NA, et al. Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitis. Dig Dis Sci. 1982 Jan;27:533–7.CrossRefPubMed Powell-Tuck J, Day DW, Bucknell NA, et al. Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitis. Dig Dis Sci. 1982 Jan;27:533–7.CrossRefPubMed
23.
Zurück zum Zitat van Hees PA, van Elteren PH, van Lier HJ, van Tongeren JH. An index of inflammatory activity in patients with Crohn’s disease. Gut. 1980;21(4):279–86.CrossRefPubMedPubMedCentral van Hees PA, van Elteren PH, van Lier HJ, van Tongeren JH. An index of inflammatory activity in patients with Crohn’s disease. Gut. 1980;21(4):279–86.CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Cohen RD. The quality of life in patients with Crohn’s disease. Aliment Pharmacol Ther. 2002;16(9):1603–9.CrossRefPubMed Cohen RD. The quality of life in patients with Crohn’s disease. Aliment Pharmacol Ther. 2002;16(9):1603–9.CrossRefPubMed
25.
Zurück zum Zitat Jowett SL, Seal CJ, Barton JR, Welfare MR. The short inflammatory bowel disease questionnaire is reliable and responsive to clinically important change in ulcerative colitis. Am J Gastroenterol. 2001;96(10):2921–8.CrossRefPubMed Jowett SL, Seal CJ, Barton JR, Welfare MR. The short inflammatory bowel disease questionnaire is reliable and responsive to clinically important change in ulcerative colitis. Am J Gastroenterol. 2001;96(10):2921–8.CrossRefPubMed
26.
Zurück zum Zitat Galgut BJ, Lemberg DA, Day AS, Leach ST. The value of fecal markers in predicting relapse in inflammatory bowel diseases. Front Pediatr. 2018;5:292.CrossRefPubMedPubMedCentral Galgut BJ, Lemberg DA, Day AS, Leach ST. The value of fecal markers in predicting relapse in inflammatory bowel diseases. Front Pediatr. 2018;5:292.CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Lewis JD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology. 2011;140(6):1817–1826.e2.CrossRefPubMed Lewis JD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology. 2011;140(6):1817–1826.e2.CrossRefPubMed
28.
Zurück zum Zitat Salazar J, Martínez MS, Chávez-Castillo M, et al. C-reactive protein: an in-depth look into structure, function, and regulation. Int Sch Res Notices. 2014;2014:653045.PubMedPubMedCentral Salazar J, Martínez MS, Chávez-Castillo M, et al. C-reactive protein: an in-depth look into structure, function, and regulation. Int Sch Res Notices. 2014;2014:653045.PubMedPubMedCentral
30.
Zurück zum Zitat Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. JSTOR. 1995;57(1):289–300. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. JSTOR. 1995;57(1):289–300.
31.
Zurück zum Zitat Madrid-Valero JJ, Martínez-Selva JM, Ribeiro do Couto B, Sánchez-Romera JF, Ordoñana JR. Age and gender effects on the prevalence of poor sleep quality in the adult population. Gac Sanit. 2017;31(1):18–22.CrossRefPubMed Madrid-Valero JJ, Martínez-Selva JM, Ribeiro do Couto B, Sánchez-Romera JF, Ordoñana JR. Age and gender effects on the prevalence of poor sleep quality in the adult population. Gac Sanit. 2017;31(1):18–22.CrossRefPubMed
32.
Zurück zum Zitat Lu CL, Chang FY, Lang HC, Chen CY, Luo JC, Lee SD. Gender difference on the symptoms, health-seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II-based survey in an apparent healthy adult Chinese population in Taiwan. Aliment Pharm. 2005;21(12):1497–505.CrossRef Lu CL, Chang FY, Lang HC, Chen CY, Luo JC, Lee SD. Gender difference on the symptoms, health-seeking behaviour, social impact and sleep quality in irritable bowel syndrome: a Rome II-based survey in an apparent healthy adult Chinese population in Taiwan. Aliment Pharm. 2005;21(12):1497–505.CrossRef
34.
Zurück zum Zitat Goodhand JR, Greig FI, Koodun Y, McDermott A, Wahed M, Langmead L, et al. Do antidepressants influence the disease course in inflammatory bowel disease? A retrospective case-matched observational study. Inflamm Bowel Dis. 2012;18(7):1232–9.CrossRefPubMed Goodhand JR, Greig FI, Koodun Y, McDermott A, Wahed M, Langmead L, et al. Do antidepressants influence the disease course in inflammatory bowel disease? A retrospective case-matched observational study. Inflamm Bowel Dis. 2012;18(7):1232–9.CrossRefPubMed
35.
Zurück zum Zitat Colombo F, Rizzi A, Ferrari C, Frontali A, Casiraghi S, Corsi F, et al. Bariatric surgery in patients with inflammatory bowel disease: an accessible path? Report of a case series and review of the literature. J Crohns Colitis. 2015;9(2):185–90.CrossRefPubMed Colombo F, Rizzi A, Ferrari C, Frontali A, Casiraghi S, Corsi F, et al. Bariatric surgery in patients with inflammatory bowel disease: an accessible path? Report of a case series and review of the literature. J Crohns Colitis. 2015;9(2):185–90.CrossRefPubMed
Metadaten
Titel
Sleep Quality in Ulcerative Colitis: Associations with Inflammation, Psychological Distress, and Quality of Life
Publikationsdatum
29.08.2018
Erschienen in
International Journal of Behavioral Medicine / Ausgabe 5/2018
Print ISSN: 1070-5503
Elektronische ISSN: 1532-7558
DOI
https://doi.org/10.1007/s12529-018-9745-9

Weitere Artikel der Ausgabe 5/2018

International Journal of Behavioral Medicine 5/2018 Zur Ausgabe