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Acta Neurologica Belgica

Erschienen in:

05.12.2017 | Original Article

Sleep quality is associated with the severity of clinical symptoms in Parkinson’s disease

verfasst von: Bruno T. Junho, Arthur Kummer, Francisco E. Cardoso, Antonio L. Teixeira, Natalia P. Rocha

Erschienen in: Acta Neurologica Belgica | Ausgabe 1/2018

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Abstract

Sleep disorders are very common in Parkinson’s disease (PD), being associated with several other conditions, mainly psychiatric disorders. The present study was designed to assess sleep quality in Brazilian patients with PD and to evaluate whether sleep changes are associated with clinical variables, especially neuropsychiatric symptoms in PD. Patients diagnosed with PD were subjected to a comprehensive clinical evaluation that included the assessment of motor, cognitive and psychiatric symptoms. Our study showed that sleep complaints are frequent in PD and worse sleep quality is associated with depressive and anxious symptoms, poorer cognitive performance and greater severity of PD symptoms. In the multivariate analysis, older age, greater severity of anxiety and PD remained as significant predictors of worse sleep quality. In conclusion, sleep complaints, depressive and anxiety symptoms are frequent in PD patients. Older age, disease severity and anxiety symptoms are significant predictors of poorer sleep quality in PD patients.

Titova N, Qamar MA, Chaudhuri KR (2017) The nonmotor features of parkinson’s disease. Int Rev Neurobiol 132:33–54. https://doi.org/10.1016/bs.irn.2017.02.016 CrossRefPubMed

Kummer A, Cardoso F, Teixeira AL (2008) Frequency of social phobia and psychometric properties of the Liebowitz social anxiety scale in Parkinson’s disease. Mov Disord 23(12):1739–1743. https://doi.org/10.1002/mds.22221 CrossRefPubMed

Kummer A, Teixeira AL (2009) Neuropsychiatry of Parkinson’s disease. Arq Neuropsiquiatr 67(3B):930–939CrossRefPubMed

Kummer A, Scalzo P, Cardoso F, Teixeira AL (2011) Evaluation of fatigue in Parkinson’s disease using the Brazilian version of Parkinson’s fatigue scale. Acta Neurol Scand 123(2):130–136. https://doi.org/10.1111/j.1600-0404.2010.01364.x CrossRefPubMed

Albers JA, Chand P, Anch AM (2017) Multifactorial sleep disturbance in Parkinson’s disease. Sleep Med 35:41–48. https://doi.org/10.1016/j.sleep.2017.03.026 CrossRefPubMed

Kummer A, Harsanyi E, Dias FM, Cardoso F, Caramelli P, Teixeira AL (2009) Depression impairs executive functioning in Parkinson disease patients with low educational level. Cogn Behav Neurol 22(3):167–172. https://doi.org/10.1097/WNN.0b013e3181b278f9 CrossRefPubMed

Martinez-Martin P, Rodriguez-Blazquez C, Kurtis MM, Chaudhuri KR (2011) The impact of non-motor symptoms on health-related quality of life of patients with Parkinson’s disease. Mov Disord 26(3):399–406. https://doi.org/10.1002/mds.23462 CrossRefPubMed

Barone P, Antonini A, Colosimo C, Marconi R, Morgante L, Avarello TP, Bottacchi E, Cannas A, Ceravolo G, Ceravolo R, Cicarelli G, Gaglio RM, Giglia RM, Iemolo F, Manfredi M, Meco G, Nicoletti A, Pederzoli M, Petrone A, Pisani A, Pontieri FE, Quatrale R, Ramat S, Scala R, Volpe G, Zappulla S, Bentivoglio AR, Stocchi F, Trianni G, Dotto PD (2009) The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson’s disease. Mov Disord 24(11):1641–1649. https://doi.org/10.1002/mds.22643 CrossRefPubMed

Dhawan V, Healy DG, Pal S, Chaudhuri KR (2006) Sleep-related problems of Parkinson’s disease. Age Ageing 35(3):220–228. https://doi.org/10.1093/ageing/afj087 CrossRefPubMed

10.

Alatriste-Booth V, Rodriguez-Violante M, Camacho-Ordonez A, Cervantes-Arriaga A (2015) Prevalence and correlates of sleep disorders in Parkinson’s disease: a polysomnographic study. Arq Neuropsiquiatr 73(3):241–245. https://doi.org/10.1590/0004-282x20140228 CrossRefPubMed

11.

French IT, Muthusamy KA (2016) A review of sleep and its disorders in patients with parkinson’s disease in relation to various brain structures. Front Aging Neurosci 8:114. https://doi.org/10.3389/fnagi.2016.00114 CrossRefPubMedPubMedCentral

12.

Diederich NJ, McIntyre DJ (2012) Sleep disorders in Parkinson’s disease: many causes, few therapeutic options. J Neurol Sci 314(1–2):12–19. https://doi.org/10.1016/j.jns.2011.10.025 CrossRefPubMed

13.

Salawu F, Olokoba A (2015) Excessive daytime sleepiness and unintended sleep episodes associated with Parkinson’s Disease. Oman Med J 30(1):3–10. https://doi.org/10.5001/omj.2015.02 CrossRefPubMedPubMedCentral

14.

Chaudhuri KR, Pal S, DiMarco A, Whately-Smith C, Bridgman K, Mathew R, Pezzela FR, Forbes A, Hogl B, Trenkwalder C (2002) The Parkinson’s disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson’s disease. J Neurol Neurosurg Psychiatry 73(6):629–635CrossRefPubMedPubMedCentral

15.

Jongwanasiri S, Prayoonwiwat N, Pisarnpong A, Srivanitchapoom P, Chotinaiwattarakul W (2014) Evaluation of sleep disorders in Parkinson’s disease: a comparison between physician diagnosis and self-administered questionnaires. J Med Assoc Thai 97(Suppl 3):S68–77PubMed

16.

Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson’s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55(3):181–184CrossRefPubMedPubMedCentral

17.

Fahn S (1987) Recent developments in Parkinson’s disease. Macmillan Health care Inf 2:293–304

18.

Goetz CG, Poewe W, Rascol O, Sampaio C, Stebbins GT, Counsell C, Giladi N, Holloway RG, Moore CG, Wenning GK, Yahr MD, Seidl L (2004) Movement disorder society task force report on the hoehn and yahr staging scale: status and recommendations. Mov Disord 19(9):1020–1028. https://doi.org/10.1002/mds.20213 CrossRefPubMed

19.

Folstein MF, Robins LN, Helzer JE (1983) The mini-mental state examination. Arch Gen Psychiatry 40(7):812CrossRefPubMed

20.

Dubois B, Slachevsky A, Litvan I, Pillon B (2000) The FAB: a frontal assessment battery at bedside. Neurology 55(11):1621–1626CrossRefPubMed

21.

Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571CrossRefPubMed

22.

Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62CrossRefPubMedPubMedCentral

23.

Hamilton M (1959) The assessment of anxiety states by rating. Br J Med Psychol 32(1):50–55CrossRefPubMed

24.

McRae C, Diem G, Vo A, O’Brien C, Seeberger L (2002) Reliability of measurements of patient health status: a comparison of physician, patient, and caregiver ratings. Parkinsonism Relat Disord 8(3):187–192CrossRefPubMed

25.

Johns MW (1991) A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14(6):540–545CrossRefPubMed

26.

Chaudhuri K, Pal S, DiMarco A, Whately-Smith C, Bridgman K, Mathew R, Pezzela F, Forbes A, Hogl B, Trenkwalder C (2002) The Parkinson’s disease sleep scale: a new instrument for assessing sleep and nocturnal disability in Parkinson’s disease. J Neurol Neurosurg Psychiatry 73(6):629–635. https://doi.org/10.1136/jnnp.73.6.629 CrossRefPubMedPubMedCentral

27.

Dissanayaka NN, Sellbach A, Silburn PA, O’Sullivan JD, Marsh R, Mellick GD (2011) Factors associated with depression in Parkinson’s disease. J Affect Disord 132(1–2):82–88. https://doi.org/10.1016/j.jad.2011.01.021 CrossRefPubMed

28.

Kummer A, Cardoso F, Teixeira AL (2010) Generalized anxiety disorder and the Hamilton Anxiety Rating Scale in Parkinson’s disease. Arq Neuropsiquiatr 68:495–501CrossRefPubMed

29.

Edwards BA, O’Driscoll DM, Ali A, Jordan AS, Trinder J, Malhotra A (2010) Aging and sleep: physiology and pathophysiology. Semin Respir Crit Care Med 31(5):618–633. https://doi.org/10.1055/s-0030-1265902 CrossRefPubMedPubMedCentral

30.

Mander BA, Winer JR, Walker MP (2017) Sleep and human aging. Neuron 94(1):19–36. https://doi.org/10.1016/j.neuron.2017.02.004 CrossRefPubMedPubMedCentral

31.

Ancoli-Israel S (2009) Sleep and its disorders in aging populations. Sleep Med 10:S7–S11. https://doi.org/10.1016/j.sleep.2009.07.004 CrossRefPubMed

32.

Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG (1995) Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep 18(6):425–432CrossRefPubMed

33.

Hood S, Amir S (2017) Neurodegeneration and the circadian clock. Front Aging Neurosci 9:170. https://doi.org/10.3389/fnagi.2017.00170 CrossRefPubMedPubMedCentral

34.

Mattis J, Sehgal A (2016) Circadian rhythms, sleep, and disorders of aging. Trends Endocrinol Metab 27(4):192–203. https://doi.org/10.1016/j.tem.2016.02.003 CrossRefPubMedPubMedCentral

35.

Dissanayaka NN, Sellbach A, Matheson S, O’Sullivan JD, Silburn PA, Byrne GJ, Marsh R, Mellick GD (2010) Anxiety disorders in Parkinson’s disease: prevalence and risk factors. Mov Disord 25(7):838–845. https://doi.org/10.1002/mds.22833 CrossRefPubMed

36.

Yamanishi T, Tachibana H, Oguru M, Matsui K, Toda K, Okuda B, Oka N (2013) Anxiety and depression in patients with Parkinson’s disease. Internal Med (Tokyo) 52(5):539–545CrossRef

37.

Leentjens AF, Dujardin K, Marsh L, Martinez-Martin P, Richard IH, Starkstein SE (2011) Symptomatology and markers of anxiety disorders in Parkinson’s disease: a cross-sectional study. Mov Disord 26(3):484–492. https://doi.org/10.1002/mds.23528 CrossRefPubMed

38.

Kummer A, Cardoso F, Teixeira AL (2010) Generalized anxiety disorder and the hamilton anxiety rating scale in Parkinson’s disease. Arq Neuropsiquiatr 68(4):495–501CrossRefPubMed

39.

Tandberg E, Larsen JP, Karlsen K (1998) A community-based study of sleep disorders in patients with Parkinson’s disease. Mov Disord 13(6):895–899. https://doi.org/10.1002/mds.870130606 CrossRefPubMed

40.

Shulman LM, Taback RL, Rabinstein AA, Weiner WJ (2002) Non-recognition of depression and other non-motor symptoms in Parkinson’s disease. Parkinsonism Relat Disord 8(3):193–197. https://doi.org/10.1016/S1353-8020(01)00015-3 CrossRefPubMed

41.

Margis R, Donis KC, Schonwald SV, Rieder CR (2010) WHOQOL-OLD assessment of quality of life in elderly patients with Parkinson’s disease: influence of sleep and depressive symptoms. Revista Brasileira de Psiquiatria (Sao Paulo) 32(2):125–131CrossRef

42.

Young A, Home M, Churchward T, Freezer N, Holmes P, Ho M (2002) Comparison of sleep disturbance in mild versus severe Parkinson’s disease. Sleep 25(5):573–577CrossRefPubMed

43.

Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17(5):427–442CrossRefPubMed

44.

Aarsland D, Andersen K, Larsen JP, Lolk A, Nielsen H, Kragh-Sorensen P (2001) Risk of dementia in Parkinson’s disease: a community-based, prospective study. Neurology 56(6):730–736CrossRefPubMed

45.

Hely MA, Reid WG, Adena MA, Halliday GM, Morris JG (2008) The Sydney multicenter study of Parkinson’s disease: the inevitability of dementia at 20 years. Mov Disord 23(6):837–844. https://doi.org/10.1002/mds.21956 CrossRefPubMed

46.

Kim EJ, Baek JH, Shin DJ, Park HM, Lee YB, Park KH, Shin DH, Noh Y, Sung YH (2014) Correlation of sleep disturbance and cognitive impairment in patients with Parkinson’s disease. J Mov Disord 7(1):13–18. https://doi.org/10.14802/jmd.14003 CrossRefPubMedPubMedCentral

47.

Goldman JG, Ghode RA, Ouyang B, Bernard B, Goetz CG, Stebbins GT (2013) Dissociations among daytime sleepiness, nighttime sleep, and cognitive status in Parkinson’s disease. Parkinsonism Relat Disord 19(9):806–811. https://doi.org/10.1016/j.parkreldis.2013.05.006 CrossRefPubMedPubMedCentral

48.

Arnulf I, Konofal E, Merino-Andreu M, Houeto JL, Mesnage V, Welter ML, Lacomblez L, Golmard JL, Derenne JP, Agid Y (2002) Parkinson’s disease and sleepiness: an integral part of PD. Neurology 58(7):1019–1024CrossRefPubMed

49.

Bjornara KA, Dietrichs E, Toft M (2014) Clinical features associated with sleep disturbances in Parkinson’s disease. Clin Neurol Neurosurg 124:37–43. https://doi.org/10.1016/j.clineuro.2014.06.027 CrossRefPubMed

50.

Prudon B, Duncan GW, Khoo TK, Yarnall AJ, Anderson KN (2014) Primary sleep disorder prevalence in patients with newly diagnosed Parkinson’s disease. Mov Disord 29(2):259–262. https://doi.org/10.1002/mds.25730 CrossRefPubMed

Titel: Sleep quality is associated with the severity of clinical symptoms in Parkinson’s disease
verfasst von: Bruno T. Junho
Arthur Kummer
Francisco E. Cardoso
Antonio L. Teixeira
Natalia P. Rocha
Publikationsdatum: 05.12.2017
Verlag: Springer International Publishing
Erschienen in: Acta Neurologica Belgica / Ausgabe 1/2018
Print ISSN: 0300-9009
Elektronische ISSN: 2240-2993
DOI: https://doi.org/10.1007/s13760-017-0868-6

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Sleep quality is associated with the severity of clinical symptoms in Parkinson’s disease

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„Restriktion auf vier Wochen Therapie bei Schlaflosigkeit ist absurd!“

Stuhltransfusion könnte Fortschreiten von Parkinson-Symptomen bremsen

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