Erschienen in:
11.05.2021 | Editorial
Spotlight on left ventricular dyssynchrony: Part 3: Diagnostic value and therapeutic guidance
verfasst von:
Saurabh Malhotra, MD MPH FASNC, Ami E. Iskandrian, MD MASNC
Erschienen in:
Journal of Nuclear Cardiology
|
Ausgabe 3/2021
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Excerpt
Temporal differences in activation and contraction of various myocardial segments of the left ventricle (LV), or LV dyssynchrony (LVD), have been shown to be a prognostic indicator of mortality and malignant arrhythmias among those with heart failure (HF) and reduced ejection fraction. In this regard, it may be useful in identification of HF patients who are unlikely to derive a benefit from a primary prevention implantable cardioverter defibrillator (ICD). In HF patients, additional mortality benefit is derived from effective cardiac resynchronization therapy (CRT). Phase analysis of gated SPECT provides a guidance criterion to improve CRT response, which includes presence of systolic LVD, scar burden, and concordance of left ventricular lead with the site of latest myocardial activation. …