Ausgabe 4/2021
Inhalt (10 Artikel)
Should the Clinical Pharmacologist Play a Role in the Multidisciplinary Team Managing Severe Necrotizing Soft-Tissue Infections?
Milo Gatti, Federico Pea
Pharmacokinetic and Pharmacodynamic Optimization of Antibiotic Therapy in Cystic Fibrosis Patients: Current Evidences, Gaps in Knowledge and Future Directions
Sophie Magréault, Charlotte Roy, Manon Launay, Isabelle Sermet-Gaudelus, Vincent Jullien
Antibiotics in Adult Cystic Fibrosis Patients: A Review of Population Pharmacokinetic Analyses
Mehdi El Hassani, Jean-Alexandre Caissy, Amélie Marsot
A Population Pharmacokinetic Analysis of PF-5190457, a Novel Ghrelin Receptor Inverse Agonist in Healthy Volunteers and in Heavy Alcohol Drinkers
Enoch Cobbina, Mary R. Lee, Lorenzo Leggio, Fatemeh Akhlaghi
Pharmacokinetics of Imeglimin in Subjects with Moderate Hepatic Impairment
Clémence Chevalier, Julie Dubourg, Sébastien Bolze, Pascale Fouqueray
The Influence of Haemostatic System Maturation on the Dose–Response Relationship of Unfractionated Heparin
Abdallah Derbalah, Stephen Duffull, Katie Moynihan, Hesham Al-Sallami
Population Pharmacokinetics of Esketamine Nasal Spray and its Metabolite Noresketamine in Healthy Subjects and Patients with Treatment-Resistant Depression
Carlos Perez-Ruixo, Stefaan Rossenu, Peter Zannikos, Partha Nandy, Jaskaran Singh, Wayne C. Drevets, Juan Jose Perez-Ruixo
Evaluation of the Pharmacokinetics and Exposure–Response Relationship of Dapagliflozin in Patients without Diabetes and with Chronic Kidney Disease
Annemarie B. van der Aart-van der Beek, Jeroen V. Koomen, Claire C. J. Dekkers, Sean J. Barbour, David W. Boulton, Ron T. Gansevoort, Peter J. Greasley, Abdul Halim Abdul Gafor, Gozewijn D. Laverman, Qiang Li, Soo Kun Lim, Jasper Stevens, Marc G. Vervloet, Sunita Singh, Daniel C. Cattran, Heather N. Reich, David Z. I. Cherney, Hiddo J. L. Heerspink
Population Pharmacokinetics of a Monthly Buprenorphine Depot Injection for the Treatment of Opioid Use Disorder: A Combined Analysis of Phase II and Phase III Trials
Aksana K. Jones, Eliford Ngaimisi, Mathangi Gopalakrishnan, Malcolm A. Young, Celine M. Laffont
Nicotine Population Pharmacokinetics in Healthy Smokers After Intravenous, Oral, Buccal and Transdermal Administration
Per O. Olsson Gisleskog, Juan José Perez Ruixo, Åke Westin, Anna C. Hansson, Paul A. Soons