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Experimental Hematology & Oncology

Ausgabe 1/2018

Inhalt (32 Artikel)

Open Access Research

WT1 peptide vaccine in Montanide in contrast to poly ICLC, is able to induce WT1-specific immune response with TCR clonal enrichment in myeloid leukemia

Hongtao Liu, Yuanyuan Zha, Noura Choudhury, Gregory Malnassy, Noreen Fulton, Margaret Green, Jae-Hyun Park, Yusuke Nakamura, Richard A. Larson, Andres M. Salazar, Olatoyosi Odenike, Thomas F. Gajewski, Wendy Stock

Open Access Case report

Complete response in advanced breast cancer patient treated with a combination of capecitabine, oral vinorelbine and dasatinib

V. Sgroi, M. Bassanelli, M. Roberto, E. Iannicelli, R. Porrini, P. Pellegrini, A. Tafuri, P. Marchetti

Open Access Case report

Deep sustained response to daratumumab monotherapy associated with T-cell expansion in triple refractory myeloma

Saad Z. Usmani, Imran Khan, Christopher Chiu, David Foureau, Lawrence J. Druhan, Katherine Rigby, Tineke Casneuf, A. Kate Sasser

Open Access Research

Cost-effectiveness of nivolumab in patients with advanced renal cell carcinoma treated in the United States

Charles McCrea, Sukhvinder Johal, Shuo Yang, Justin Doan

Open Access Rapid communication

Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies

Julien Magne, Alizée Jenvrin, Adrien Chauchet, Olivier Casasnovas, Anne Donzel, Laurence Jego, Bernard Aral, Julien Guy, Nathalie Nadal, Dewi Vernerey, Patrick Callier, Francine Garnache-Ottou, Christophe Ferrand

Open Access Case report

Aplastic anemia secondary to nivolumab and ipilimumab in a patient with metastatic melanoma: a case report

D. E. Meyers, W. F. Hill, A. Suo, V. Jimenez-Zepeda, T. Cheng, N. A. Nixon

Open Access Case report

PAN3–PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia

Ioannis Panagopoulos, Ludmila Gorunova, Hege Kilen Andersen, Astrid Bergrem, Anders Dahm, Kristin Andersen, Francesca Micci, Sverre Heim

Open Access Research

Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration

Magnus Aassved Hjort, Håkon Hov, Pegah Abdollahi, Esten Nymoen Vandsemb, Unn-Merete Fagerli, Bendik Lund, Tobias Schmidt Slørdahl, Magne Børset, Torstein Baade Rø

Open Access Research

Correlation of plasma concentration and adverse effects of bosutinib: standard dose or dose-escalation regimens of bosutinib treatment for patients with chronic myeloid leukemia

Akiko Mita, Maiko Abumiya, Masatomo Miura, Takenori Niioka, Saori Takahashi, Tomoko Yoshioka, Yoshihiro Kameoka, Naoto Takahashi

Open Access Rapid communication

An integrated view of the role of miR-130b/301b miRNA cluster in prostate cancer

Rafael Sebastián Fort, Cecilia Mathó, Carolina Oliveira-Rizzo, Beatriz Garat, José Roberto Sotelo-Silveira, María Ana Duhagon

Open Access Case report

Conservative management of nivolumab-induced pericardial effusion: a case report and review of literature

Shagufta Shaheen, Hamid Mirshahidi, Gayathri Nagaraj, Chung-Tsen Hsueh

Open Access Research

Phase 2 study of everolimus for relapsed or refractory classical Hodgkin lymphoma

Patrick B. Johnston, Lauren C. Pinter-Brown, Ghulam Warsi, Kristen White, Radhakrishnan Ramchandren

Open Access Research

Understanding metabolic changes in aging bone marrow

Kwasi M. Connor, Young Hsu, Pardeep Kumar Aggarwal, Stephen Capone, Anthony R. Colombo, Giridharan Ramsingh

Open Access Review

Bullous hemorrhagic dermatosis is an under-recognized side effect of full dose low-molecular weight heparin: a case report and review of the literature

Armand Russo, Susanna Curtis, Raisa Balbuena-Merle, Roxanne Wadia, Ellice Wong, Herta H. Chao

Open Access Research

Are patients with high-risk polycythemia vera receiving cytoreductive medications? A retrospective analysis of real-world data

Dilan Paranagama, Philomena Colucci, Kristin A. Evans, Machaon Bonafede, Shreekant Parasuraman

Open Access Review

Emerging therapies in advanced hepatocellular carcinoma

Sowmini Medavaram, Yue Zhang

Open Access Research

A randomized placebo-controlled phase II study of clarithromycin or placebo combined with VCD induction therapy prior to high-dose melphalan with stem cell support in patients with newly diagnosed multiple myeloma

Henrik Gregersen, Trung Do, Ida Bruun Kristensen, Ulf Christian Frølund, Niels Frost Andersen, Lene Kongsgaard Nielsen, Christen Lykkegaard Andersen, Tobias Wirenfeldt Klausen, Annette Juul Vangsted, Niels Abildgaard

Open Access Research

The association of HLA-C alleles with multiple myeloma in Chinese patients

Xiaojing Wang, Gang An, Jiying Wang, Yan Zhang, Qinghua Li, Hui wei, Lugui Qiu, Kun Ru

Open Access Case report

Metastatic squamous cell carcinoma of the skin with clinical response to lapatinib

John D. Strickley, Aaron C. Spalding, M. Tye Haeberle, Timothy Brown, Don A. Stevens, Jae Jung

Open Access Case report

Personalized prescription of tyrosine kinase inhibitors in unresectable metastatic cholangiocarcinoma

Elena V. Poddubskaya, Madina P. Baranova, Daria O. Allina, Philipp Y. Smirnov, Eugene A. Albert, Alexey P. Kirilchev, Alexey A. Aleshin, Marina I. Sekacheva, Maria V. Suntsova

Open Access Research

Temporality of heparin-induced antibodies: a retrospective study in outpatients undergoing hemodialysis on unfractionated heparin

Satish Maharaj, Simone Chang, Karan Seegobin, James Morales, Agnes Aysola, Fauzia Rana, Marwan Shaikh

Open Access Review

Mechanisms for estrogen receptor expression in human cancer

Hui Hua, Hongying Zhang, Qingbin Kong, Yangfu Jiang

Open Access Short report

Induction of anti-leukemic responses by stimulation of leukemic CD3+ cells with allogeneic stimulator cells

Alejandro Pando, John L. Reagan, Martha Nevola, Loren D. Fast

Open Access Case report

Early detection of transformation to BPDCN in a patient with MDS

Kamal Chamoun, Sanam Loghavi, Naveen Pemmaraju, Marina Konopleva, Michael Kroll, Madeleine Nguyen-Cao, Marisa Hornbaker, Courtney D. DiNardo, Tapan Kadia, Jeffrey Jorgensen, Michael Andreeff, Shimin Hu, Christopher B. Benton

Open Access Research

Daratumumab binds to mobilized CD34+ cells of myeloma patients in vitro without cytotoxicity or impaired progenitor cell growth

Xun Ma, Sandy W. Wong, Ping Zhou, Chakra P. Chaulagain, Parul Doshi, Andreas K. Klein, Kellie Sprague, Adin Kugelmass, Denis Toskic, Melissa Warner, Kenneth B. Miller, Lisa Lee, Cindy Varga, Raymond L. Comenzo

Open Access Review

The role of neoantigen in immune checkpoint blockade therapy

Ming Yi, Shuang Qin, Weiheng Zhao, Shengnan Yu, Qian Chu, Kongming Wu

Open Access Research

Early vs. late MRD response- and risk-based treatment intensification of childhood acute lymphoblastic leukemia: a prospective pilot study from Saudi Arabia

Wasil Jastaniah, Naglla Elimam, Khalid Abdalla, Aeshah A. AlAzmi, Aml M. Elgaml, Ahmad Alkassar, Mustafa Daghistani, Sami Felimban

Open Access Review

Organoid technology in disease modelling, drug development, personalized treatment and regeneration medicine

Hanxiao Xu, Ying Jiao, Shuang Qin, Weiheng Zhao, Qian Chu, Kongming Wu

Open Access Research

The epidemiology and clinical characteristics of myeloproliferative neoplasms in Malaysia

Yee Yee Yap, Kian Boon Law, Jameela Sathar, Ngee Siang Lau, Ai Sim Goh, Teng Keat Chew, Soo Min Lim, Padmini Menon, Yong Khee Guan, Azlan Bin Husin, Lily Lee Lee Wong, Lee Ping Chew, Sinari Salleh, Kim Yen Goh, Kin Wah Leong, Sen Mui Tan, Tee Chuan Ong, Su Hong Lim, See Guan Toh, Xavier Sim Yoon Han, Syed Carlo Edmund, Jenq Tzong Tan, Kian Meng Chang

Open Access Research

Methylome of human senescent hematopoietic progenitors

Stephen Capone, Anthony R. Colombo, Benjamin K. Johnson, Tim J. Triche Jr., Giridharan Ramsingh

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

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