Ausgabe 2/2018
Special Issue: Optimizing Animal Models for HAND; Guest Editor: Jeymohan Joseph
Inhalt (13 Artikel)
Optimizing animal models for HIV-associated CNS dysfunction and CNS reservoir research
Jeymohan Joseph
When do models of NeuroAIDS faithfully imitate “the real thing”?
Benjamin B. Gelman, Janice Endsley, Dennis Kolson
Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research
Victoria E. Thaney, Ana B. Sanchez, Jerel A. Fields, Arpi Minassian, Jared W. Young, Ricky Maung, Marcus Kaul
Doxycycline-inducible and astrocyte-specific HIV-1 Tat transgenic mice (iTat) as an HIV/neuroAIDS model
Dianne Langford, Byung oh Kim, Wei Zou, Yan Fan, Pejman Rahimain, Ying Liu, Johnny J. He
A mouse model of HIV-associated neurocognitive disorders: a brain-behavior approach to discover disease mechanisms and novel treatments
William R. Tyor, Heather Bimonte-Nelson
Humanized mice: models for evaluating NeuroHIV and cure strategies
Jenna B. Honeycutt, J. Victor Garcia
HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency
George N. Llewellyn, David Alvarez-Carbonell, Morgan Chateau, Jonathan Karn, Paula M. Cannon
An SIV/macaque model targeted to study HIV-associated neurocognitive disorders
Sarah E. Beck, Suzanne E. Queen, Kelly A. Metcalf Pate, Lisa M. Mangus, Celina M. Abreu, Lucio Gama, Kenneth W. Witwer, Robert J. Adams, M. Christine Zink, Janice E. Clements, Joseph L. Mankowski
An SIV macaque model of SIV and HAND: the need for adjunctive therapies in HIV that target activated monocytes and macrophages
Jaclyn Mallard, Kenneth Williams
Evolution of the HIV-1 transgenic rat: utility in assessing the progression of HIV-1-associated neurocognitive disorders
Kristen A. McLaurin, Rosemarie M. Booze, Charles F. Mactutus
Cigarette smoke and nicotine effects on brain proinflammatory responses and behavioral and motor function in HIV-1 transgenic rats
Walter Royal III, Adem Can, Todd D. Gould, Ming Guo, Jared Huse, Myles Jackson, Harry Davis, Joseph Bryant