Background
Methods
Patients
Characteristic | Primary cardiac cancer of remnant stomach | Primary cardiac cancer | X 2/t | P value |
---|---|---|---|---|
Age (years) | 61.54 ± 8.84 | 61.59 ± 8.31 | −0.035 | 0.972 |
Gender | 0.000 | 1.000 | ||
Male | 44 | 88 | ||
Female | 4 | 8 | ||
Borrmann type | −0.954 | 0.342 | ||
I | 4 | 0 | ||
II | 14 | 30 | ||
III | 26 | 62 | ||
IV | 4 | 4 | ||
Tumor size (cm) | 5.9 ± 2.2 | 6.2 ± 3.1 | −0.634 | 0.527 |
Histological type | −1.223 | 0.224 | ||
Undifferentiated | 15 | 21 | ||
Differentiated | 33 | 75 | ||
Depth of invasion | 0.000 | 1.000 | ||
T1 | 2 | 4 | ||
T2 | 6 | 12 | ||
T3 | 18 | 36 | ||
T4a | 22 | 44 | ||
Lymph node metastasis | 0.000 | 1.000 | ||
N0 | 20 | 40 | ||
N1 | 10 | 20 | ||
N2 | 14 | 28 | ||
N3 | 4 | 8 | ||
Positive lymph nodes (n) | 2.7 ± 3.8 | 2.8 ± 4.2 | 0.000 | 0.873 |
Dissected lymph nodes (n) | 18.0 ± 5.8 | 26.9 ± 8.9 | 1.000 | 0.000 |
Lymph node dissection pattern | 0.000 | 1.000 | ||
D1 | 6 | 12 | ||
D2/D2+ | 42 | 84 | ||
Combined organ resection | 8 (16.7%) | 24 (25.0%) | −1.131 | 0.260 |
Surgical approaches
Postoperative follow-up
Statistical analysis
Ethical approval
Results
Patient prognosis
Univariate analysis of factors prognostic for survival in all patients
Variables | Patients ( n) | 5-year survivalrate (%) | X 2 | P value |
---|---|---|---|---|
Gender | 0.646 | 0.422 | ||
Male | 132 | 25.1 | ||
Female | 12 | 16.7 | ||
Age (years) | 3.794 | 0.051 | ||
≥60 | 92 | 19.7 | ||
<60 | 52 | 33.1 | ||
Tumor size (cm) | 8.175 | 0.004 | ||
≥5 | 103 | 21.2 | ||
<5 | 41 | 31.8 | ||
Serosal invasion | 11.045 | 0.001 | ||
Yes | 124 | 21.5 | ||
No | 24 | 37.5 | ||
Lymph node metastasis | 14.552 | 0.000 | ||
Yes | 84 | 17.9 | ||
No | 60 | 33.7 | ||
Histological type | 0.936 | 0.333 | ||
Differentiated | 108 | 25.1 | ||
Undifferentiated | 36 | 22.2 | ||
Combined organ resection | 0.112 | 0.737 | ||
Yes | 32 | 33.7 | ||
No | 112 | 22.9 | ||
Borrmann type | 1.998 | 0.573 | ||
I | 4 | 25.0 | ||
II | 44 | 20.2 | ||
III | 88 | 27.1 | ||
IV | 8 | 12.5 | ||
Tumor location | 4.460 | 0.035 | ||
Cardiac region of the remnant stomach | 48 | 16.7 | ||
Cardiac region | 96 | 28.4 |
Multivariate analysis of prognostic factors for survival in all patients
Variables | B | SE | Wald |
P
| RR | 95% CI |
---|---|---|---|---|---|---|
Tumor size | 0.133 | 0.266 | 0.251 | 0.616 | 1.143 | 0.678–1.925 |
Serosal invasion | 0.614 | 0.304 | 4.094 | 0.043 | 1.848 | 1.019–3.350 |
Lymph node metastasis | 0.577 | 0.254 | 5.170 | 0.023 | 1.780 | 1.083–2.927 |
Tumor location | −0.507 | 0.205 | 6.093 | 0.014 | 0.602 | 0.403–0.901 |
Impact of independent prognostic factors for survival in patients with cardiac cancer of the remnant stomach and primary cardiac cancer
Variables | Primary cardiac cancer of remnant stomach, n(%) | Primary cardiac cancer, n(%) |
X
2
| P value |
---|---|---|---|---|
Serosal invasion | ||||
Yes | 40 (15.0) | 80 (25.0) | 4.176 | 0.041 |
No | 8 (25.0) | 16 (43.8) | 1.542 | 0.214 |
Lymph node metastasis | ||||
Yes | 28 (10.7) | 56 (21.6) | 6.236 | 0.013 |
No | 20 (25.0) | 40 (38.8) | 1.294 | 0.255 |
Mortality and complication rates
Variables | Primary cardiac cancer of remnant stomach (n = 48) | Primary cardiac cancer (n = 96) | P value |
---|---|---|---|
Mortality | 0 | 0 | 1.000 |
Overall complication | 10 (20.8) | 11 (11.5) | 0.138 |
Surgical complication | 5 (10.4) | 5 (6.7) | 0.255 |
Anastomotic leak | 1 (2.1) | 2 (2.1) | |
Subdiaphragmatic abscess | 0 | 1 (1.0) | |
Anastomotic stricture | 2 (4.2) | 1 (1.0) | |
Abdominal abscess | 2 (4.2) | 1 (1.0) | |
Non-surgical complication | 5 (10.4) | 6 (6.3) | 0.380 |
Pneumonia | 2 (4.2) | 3 (3.1) | |
Cardiac | 0 | 1 (1.0) | |
Abnormal liver function | 2 (4.2) | 1 (1.0) | |
Other infection | 1 (2.1) | 2 (2.1) |