Background
Methods
Subjects and ethical consideration
Actigraphy
Data analysis
Ethical considerations
Results
Threshold validation
Temporal organization of rest and activity of control and CCFS subjects
Quantitative analysis of rest duration
No. | Basic parameters | Power law vs. exponential | Power law test | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
24h | UP | DOWN | |||||||||||||
n | <x> | Total | sd | LR | p | LR | p | LR | p | xmax | xmin | α | ntail | p’ | |
1 | 570 | 12.3 | 6998 | 34.8 | 12.4 |
0.00
| 1.5 | 0.13 | -6.8 |
0.00
| 416 | 1 | 1.66 | 570 |
0.14
|
2 | 652 | 10.9 | 7111 | 48.0 | 9.9 |
0.00
| 1.9 |
0.06
| -3.1 |
0.00
| 468 | 1 | 1.82 | 652 | 0.01 |
3 | 340 | 18.9 | 6424 | 62.8 | 12.4 |
0.00
| 1.6 | 0.12 | -0.8 | 0.40 | 439 | 1 | 1.67 | 340 | 0.10 |
4 | 627 | 12.6 | 7870 | 53.5 | 11.7 |
0.00
| 0.6 | 0.52 | -3.4 |
0.00
| 660 | 2 | 1.87 | 342 | 0.00 |
5 | 636 | 10.5 | 6657 | 36.0 | 14.3 |
0.00
| 1.0 | 0.31 | -2.8 |
0.01
| 342 | 1 | 1.82 | 636 | 0.00 |
6 | 864 | 9.3 | 8005 | 34.2 | 11.4 |
0.00
| 1.3 | 0.20 | -5.1 |
0.00
| 395 | 2 | 1.90 | 486 | 0.01 |
7 | 782 | 8.7 | 6825 | 35.7 | 9.1 |
0.00
| 1.0 | 0.31 | -2.5 |
0.01
| 420 | 1 | 1.80 | 782 | 0.00 |
8 | 719 | 10.4 | 7469 | 40.7 | 9.5 |
0.00
| 1.2 | 0.23 | -2.1 |
0.03
| 446 | 2 | 1.85 | 407 |
0.23
|
9 | 1035 | 7.8 | 8083 | 25.6 | 12.2 |
0.00
| 0.9 | 0.35 | -10.6 |
0.00
| 250 | 2 | 1.88 | 539 | 0.03 |
10 | 687 | 10.8 | 7420 | 47.1 | 9.7 |
0.00
| 2.5 |
0.01
| -2.6 |
0.01
| 444 | 1 | 1.80 | 687 | 0.02 |
11 | 561 | 10.8 | 6050 | 34.6 | 13.7 |
0.00
| 1.6 | 0.11 | -1.5 | 0.15 | 406 | 1 | 1.79 | 561 | 0.00 |
12 | 990 | 8.9 | 8828 | 40.4 | 8.1 |
0.00
| 1.0 | 0.34 | -5.3 |
0.00
| 688 | 2 | 1.91 | 556 | 0.02 |
13 | 759 | 9.0 | 6804 | 20.0 | 8.3 |
0.00
| 2.2 |
0.03
| -9.8 |
0.00
| 185 | 2 | 1.73 | 449 | 0.00 |
14 | 680 | 11.4 | 7738 | 38.5 | 10.8 |
0.00
| 2.2 | 0.02 | -4.4 |
0.00
| 461 | 1 | 1.70 | 680 |
0.14
|
15 | 223 | 12.3 | 2750 | 58.2 | 6.8 |
0.00
| 3.2 |
0.00
| 1.6 | 0.12 | 475 | 1 | 1.90 | 223 |
0.21
|
16 | 489 | 7.3 | 3568 | 30.3 | 5.3 |
0.00
| 1.2 |
0.23
| -1.0 | 0.33 | 424 | 2 | 1.98 | 282 | 0.01 |
17 | 246 | 12.1 | 2967 | 29.5 | 10.4 |
0.00
| 3.5 |
0.00
| -1.8 | 0.08 | 184 | 1 | 1.67 | 246 | 0.03 |
18 | 415 | 10.6 | 4393 | 30.6 | 10.6 |
0.00
| 2.3 |
0.02
| -6.8 |
0.00
| 311 | 1 | 1.71 | 415 |
0.21
|
19 | 409 | 10.8 | 4416 | 53.1 | 8.3 |
0.00
| 1.4 | 0.15 | -2.2 |
0.03
| 464 | 1 | 1.93 | 409 | 0.04 |
20 | 381 | 6.6 | 2505 | 34.3 | 6.3 |
0.00
| 0.8 | 0.42 | 1.0 | 0.33 | 396 | 2 | 2.19 | 174 | 0.03 |
21 | 503 | 10.7 | 5359 | 37.2 | 8.3 |
0.00
| 3.2 |
0.00
| -1.1 | 0.27 | 332 | 2 | 1.80 | 281 |
0.11
|
22 | 290 | 13.5 | 3928 | 56.1 | 9.5 |
0.00
| 1.8 | 0.07 | -1.4 | 0.18 | 501 | 1 | 1.85 | 290 | 0.01 |
23 | 629 | 12.5 | 7861 | 52.3 | 10.4 |
0.00
| 1.4 | 0.16 | -2.3 |
0.02
| 501 | 2 | 1.87 | 377 |
0.20
|
mean | 586 | 10.8 | 6088 | 10.0 |
0.05>
| 1.7 |
0.05>
| -3.3 |
0.05>
| 418 | 1.4 | 1.83 | 451 |
0.1<
| |
s.d. | 221 | 2.5 | 1933 | 2.3 |
23
| 0.8 |
8
| 3.0 |
15
| 121 | 0.5 | 0.1 | 169 |
7
|
No. | Basic parameters | Power Law vs. exponential | Power law test | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
24h | UP | DOWN | |||||||||||||
n | <x> | Total | sd | LR | p | LR | p | LR | p | xmax | xmin | α | ntail | p’ | |
1 | 2286 | 7.7 | 17608 | 21.8 | 8.7 |
0.00
| 2.0 |
0.04
| 0.7 | 0.50 | 301 | 4 | 1.91 | 758 | 0.02 |
2 | 783 | 7.9 | 6218 | 28.7 | 12.1 |
0.00
| 0.8 | 0.41 | -0.2 | 0.83 | 344 | 1 | 1.87 | 783 | 0.00 |
3 | 449 | 21.4 | 9595 | 56.2 | 17.4 |
0.00
| 2.0 |
0.04
| -0.8 | 0.41 | 426 | 1 | 1.61 | 449 | 0.00 |
4 | 366 | 12.3 | 4514 | 37.1 | 8.0 |
0.00
| 1.4 | 0.15 | 0.6 | 0.56 | 401 | 1 | 1.64 | 366 |
0.42
|
5 | 642 | 8.5 | 5466 | 40.4 | 6.6 |
0.00
| 1.8 | 0.07 | -1.2 | 0.23 | 549 | 1 | 1.81 | 642 | 0.00 |
6 | 509 | 13.1 | 6668 | 53.2 | 10.8 |
0.00
| 1.6 | 0.11 | -1.0 | 0.34 | 512 | 1 | 1.78 | 509 | 0.01 |
7 | 322 | 17.5 | 5646 | 62.7 | 6.6 |
0.00
| 1.4 | 0.16 | -0.3 | 0.78 | 592 | 2 | 1.69 | 215 |
0.26
|
8 | 965 | 13.0 | 12566 | 43.5 | 12.3 |
0.00
| 3.3 |
0.00
| -1.5 | 0.13 | 541 | 2 | 1.73 | 555 | 0.05 |
9 | 1264 | 10.8 | 13604 | 55.1 | 12.5 |
0.00
| 3.0 |
0.00
| -1.5 | 0.14 | 683 | 1 | 1.88 | 1264 | 0.00 |
10 | 1239 | 9.3 | 11475 | 44.5 | 13.9 |
0.00
| 3.2 |
0.00
| -2.0 |
0.05
| 501 | 2 | 2.02 | 631 | 0.00 |
11 | 507 | 11.2 | 5678 | 55.8 | 5.7 |
0.00
| -0.3 | 0.73 | -0.3 | 0.73 | 558 | 2 | 1.85 | 298 | 0.00 |
12 | 577 | 13.5 | 7806 | 46.7 | 15.1 |
0.00
| 1.6 | 0.12 | -1.7 | 0.09 | 371 | 1 | 1.76 | 577 | 0.02 |
13 | 1625 | 8.9 | 14494 | 31.2 | 16.3 |
0.00
| 0.1 | 0.95 | -0.6 | 0.52 | 356 | 1 | 1.79 | 1625 | 0.00 |
14 | 1168 | 11.8 | 13771 | 40.5 | 7.6 |
0.00
| 0.2 | 0.81 | -0.7 | 0.51 | 573 | 7 | 2.13 | 383 | 0.02 |
15 | 1050 | 12.0 | 12567 | 49.0 | 15.4 |
0.00
| 1.4 | 0.15 | -1.8 | 0.07 | 469 | 1 | 1.81 | 1050 | 0.00 |
16 | 1529 | 10.6 | 16184 | 36.0 | 9.8 |
0.00
| 4.0 |
0.00
| -1.3 | 0.19 | 537 | 3 | 1.83 | 696 |
0.28
|
17 | 1226 | 9.9 | 12123 | 51.7 | 11.3 |
0.00
| 1.1 | 0.27 | -1.5 | 0.14 | 592 | 2 | 2.00 | 656 | 0.00 |
18 | 491 | 9.6 | 4723 | 42.9 | 7.6 |
0.00
| 2.6 |
0.01
| 0.4 | 0.72 | 470 | 1 | 1.83 | 491 | 0.00 |
19 | 842 | 10.5 | 8850 | 39.0 | 10.1 |
0.00
| 1.8 | 0.07 | -0.9 | 0.38 | 488 | 2 | 1.82 | 483 |
0.73
|
20 | 1787 | 8.5 | 15131 | 36.1 | 14.9 |
0.00
| 4.3 |
0.00
| -1.4 | 0.15 | 479 | 1 | 1.87 | 1787 | 0.00 |
21 | 171 | 21.9 | 3741 | 72.4 | 9.2 |
0.00
| 1.0 | 0.30 | 0.2 | 0.85 | 579 | 1 | 1.66 | 171 | 0.00 |
22 | 572 | 12.7 | 7241 | 40.6 | 13.0 |
0.00
| 2.4 |
0.02
| -0.2 | 0.88 | 375 | 1 | 1.70 | 572 | 0.02 |
23 | 555 | 10.6 | 5870 | 36.3 | 10.6 |
0.00
| 1.7 | 0.09 | 0.5 | 0.61 | 468 | 1 | 1.74 | 555 | 0.01 |
24 | 2244 | 8.1 | 18070 | 33.3 | 12.3 |
0.00
| 4.4 |
0.00
| -2.3 |
0.02
| 457 | 2 | 1.92 | 1262 | 0.00 |
25 | 1029 | 7.5 | 7738 | 27.1 | 9.1 |
0.00
| 1.2 | 0.24 | -0.7 | 0.47 | 351 | 2 | 1.92 | 575 |
0.38
|
26 | 1073 | 11.8 | 12610 | 28.8 | 17.9 |
0.00
| 1.4 | 0.17 | -1.7 | 0.09 | 233 | 1 | 1.63 | 1073 | 0.00 |
27 | 550 | 10.8 | 5964 | 43.5 | 10.4 |
0.00
| 4.1 |
8.00
| -0.6 | 0.58 | 454 | 2 | 1.88 | 294 | 0.01 |
28 | 706 | 9.2 | 6495 | 24.4 | 10.0 |
0.00
| 1.7 | 0.08 | -1.3 | 0.20 | 227 | 2 | 1.80 | 438 |
0.10
|
29 | 545 | 13.8 | 7527 | 32.3 | 12.3 |
0.00
| 5.7 |
0.00
| 0.2 | 0.82 | 384 | 1 | 1.59 | 545 | 0.00 |
30 | 1050 | 9.3 | 9756 | 33.4 | 8.5 |
0.00
| 4.7 |
0.00
| -0.6 | 0.56 | 383 | 3 | 1.90 | 463 |
0.37
|
31 | 1278 | 8.9 | 11314 | 19.1 | 3.2 |
0.00
| 1.3 | 0.21 | -1.2 | 0.22 | 207 | 7 | 1.99 | 348 | 0.00 |
32 | 903 | 10.7 | 9647 | 39.3 | 12.4 |
0.00
| 2.1 |
0.04
| -1.6 | 0.11 | 470 | 1 | 1.75 | 903 | 0.03 |
33 | 1994 | 7.7 | 15294 | 35.8 | 11.0 |
0.00
| 5.0 |
0.00
| -2.5 |
0.01
| 504 | 2 | 1.97 | 1069 | 0.00 |
34 | 1472 | 15.7 | 23068 | 55.8 | 5.6 |
0.00
| 2.7 |
0.01
| -1.0 | 0.31 | 1007 | 7 | 1.83 | 454 | 0.01 |
35 | 1119 | 10.8 | 12141 | 58.5 | 11.3 |
0.00
| 3.1 |
0.00
| -1.3 | 0.18 | 866 | 2 | 2.00 | 610 | 0.00 |
36 | 543 | 15.4 | 8387 | 58.5 | 12.8 |
0.00
| 2.8 |
0.01
| -1.6 | 0.11 | 501 | 1 | 1.73 | 543 | 0.00 |
37 | 594 | 11.8 | 7038 | 46.9 | 9.4 |
0.00
| 2.1 |
0.04
| 0.2 | 0.82 | 568 | 1 | 1.73 | 594 |
0.29
|
38 | 1077 | 10.8 | 11591 | 38.0 | 14.3 |
0.00
| 2.7 |
0.01
| -1.2 | 0.22 | 422 | 1 | 1.75 | 1077 | 0.07 |
39 | 1812 | 10.0 | 18073 | 32.8 | 17.6 |
0.00
| 2.0 |
0.05
| -2.1 |
0.04
| 345 | 2 | 1.84 | 1051 | 0.00 |
40 | 1690 | 10.0 | 16965 | 27.9 | 13.9 |
0.00
| 3.1 |
0.00
| -0.5 | 0.61 | 372 | 2 | 1.75 | 1009 | 0.07 |
41 | 756 | 9.2 | 6991 | 33.3 | 8.4 |
0.00
| 2.6 |
0.01
| -0.9 | 0.35 | 434 | 3 | 1.94 | 324 | 0.07 |
42 | 1646 | 10.8 | 17749 | 35.0 | 14.4 |
0.00
| 1.8 | 0.07 | -1.2 | 0.24 | 483 | 2 | 1.78 | 1004 | 0.09 |
43 | 1542 | 12.0 | 18481 | 52.4 | 13.0 |
0.00
| 1.4 | 0.17 | -0.8 | 0.43 | 809 | 2 | 1.82 | 867 | 0.00 |
44 | 1850 | 8.2 | 15235 | 27.3 | 12.2 |
0.00
| 2.2 |
0.03
| 0.2 | 0.81 | 444 | 3 | 1.91 | 739 | 0.00 |
45 | 1542 | 12.0 | 18481 | 52.4 | 13.0 |
0.00
| 1.4 | 0.17 | -0.8 | 0.43 | 809 | 2 | 1.82 | 867 | 0.00 |
46 | 1096 | 8.0 | 8746 | 31.3 | 13.5 |
0.00
| 1.5 | 0.14 | -1.9 | 0.06 | 364 | 2 | 1.98 | 568 | 0.00 |
47 | 1316 | 11.7 | 15350 | 49.4 | 17.5 | 0.00 | 2.4 |
0.02
| -1.2 | 0.21 | 567 | 2 | 1.92 | 727 | 0.00 |
48 | 425 | 9.8 | 4153 | 30.7 | 7.9 |
0.00
| 3.8 |
0.00
| -0.4 | 0.70 | 281 | 1 | 1.70 | 425 |
0.18
|
49 | 1159 | 9.3 | 10780 | 26.3 | 6.8 |
0.00
| 2.8 |
0.01
| -0.8 | 0.41 | 267 | 5 | 1.90 | 356 |
0.20
|
50 | 785 | 11.7 | 9212 | 39.8 | 12.1 |
0.00
| 4.8 |
0.00
| -0.2 | 0.81 | 439 | 1 | 1.70 | 785 |
0.18
|
51 | 580 | 10.8 | 6272 | 58.0 | 6.8 |
0.00
| 4.5 |
0.00
| -0.9 | 0.39 | 704 | 2 | 1.94 | 328 | 0.02 |
52 | 2239 | 9.4 | 20994 | 52.5 | 10.4 |
0.00
| 0.9 | 0.36 | -1.6 | 0.12 | 720 | 3 | 2.06 | 945 | 0.00 |
53 | 562 | 16.7 | 9385 | 56.3 | 16.9 |
0.00
| 1.2 | 0.22 | -0.5 | 0.63 | 520 | 1 | 1.74 | 562 | 0.00 |
54 | 916 | 16.1 | 14710 | 50.6 | 24.4 |
0.00
| 8.6 |
0.00
| -2.3 |
0.02
| 410 | 1 | 1.73 | 916 | 0.00 |
55 | 798 | 13.0 | 10413 | 37.6 | 14.2 |
0.00
| 5.4 |
0.00
| 0.2 | 0.85 | 502 | 1 | 1.64 | 798 | 0.09 |
56 | 1272 | 8.9 | 11302 | 38.0 | 12.2 |
0.00
| 2.2 |
0.03
| -2.2 |
0.03
| 396 | 1 | 1.83 | 1272 | 0.00 |
57 | 612 | 9.8 | 5996 | 39.4 | 5.6 |
0.00
| 0.8 | 0.45 | 0.9 | 0.39 | 435 | 4 | 2.05 | 250 | 0.01 |
mean | 1047 | 11.3 | 11008 | 11.5 |
0.05>
| 2.5 |
0.05>
| -0.9 |
0.05>
| 482 | 2.0 | 1.83 | 694 |
0.1<
| |
s.d. | 530 | 3.1 | 4761 | 3.9 |
57
| 1.6 |
31
| 0.8 |
6
| 156 | 1.5 | 0.1 | 341 |
11
|