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Sport Sciences for Health

Erschienen in:

01.08.2015 | Original Article

The angiotensin I-converting enzyme I/D gene polymorphism in well-trained Malaysian athletes

verfasst von: Hazwani Ahmad Yusof, Rabinderjeet Singh, Zafarina Zainuddin, Kieron Rooney, Ahmad Munir Che Muhammed

Erschienen in: Sport Sciences for Health | Ausgabe 2/2015

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Abstract

Purpose

The purpose of this study was to examine the effect of the angiotensin I-converting enzyme (ACE) I/D gene polymorphism on athletic status and physical performance of well-trained Malaysian athletes.

Methods

180 well-trained athletes (34 endurance, 41 strength/power, and 105 intermittent athletes) and 180 sedentary controls involved in the study. A sample of DNA was retrieved via buccal cell from each subject and the polymorphism was then identified through Polymerase Chain Reaction. The endurance performance and leg strength of athletes were evaluated with twenty meters Yo–Yo intermittent recovery level 2 and maximal voluntary contraction tests, respectively. Chi-square test and one-way ANOVA were used for data analysis.

Results

The II genotype was more prevalent among the endurance athletes (0.38) compared to the intermittent athletes (0.14), strength/power athletes (0.05), and controls (0.31) (p = 0.00). Conversely, the DD genotype was more prevalent among the strength/power athletes (0.66) compared to the endurance athletes (0.26), intermittent athletes (0.47), and controls (0.15). The endurance performance was not significantly associated with ACE genotype in the athletes (p = 0.828). However, athletes with the DD genotype had a better result for leg strength (113.8 ± 36.2) compared to those with the II (96.2 ± 28.0) and the ID (112.2 ± 33.5) genotypes (p = 0.047).

Conclusion

This study reaffirms previous finding reported in Caucasian samples for the association of I and D alleles with endurance and strength/power performance, respectively. The finding of this study highlights the importance of genetic screening in identifying future sporting talents.

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Titel: The angiotensin I-converting enzyme I/D gene polymorphism in well-trained Malaysian athletes
verfasst von: Hazwani Ahmad Yusof
Rabinderjeet Singh
Zafarina Zainuddin
Kieron Rooney
Ahmad Munir Che Muhammed
Publikationsdatum: 01.08.2015
Verlag: Springer Milan
Erschienen in: Sport Sciences for Health / Ausgabe 2/2015
Print ISSN: 1824-7490
Elektronische ISSN: 1825-1234
DOI: https://doi.org/10.1007/s11332-015-0222-4

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Conclusion

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