Skip to main content
Erschienen in: International Urogynecology Journal 3/2014

01.03.2014 | Original Article

The effectiveness of urinary incontinence treatments measured using the 15D Health-Related Quality of Life instrument

verfasst von: Aura Pyykönen, Pasi Aronen, Pirjo Räsänen, Risto P. Roine, Jari Sjöberg, Anna-Maija Tapper

Erschienen in: International Urogynecology Journal | Ausgabe 3/2014

Einloggen, um Zugang zu erhalten

Abstract

Introduction and hypothesis

The health-related quality of life (HRQoL) is significantly impaired among urinary incontinent women and the effectiveness of urinary incontinence (UI) treatment should be measured using an HRQoL instrument.

Methods

A prospective, observational study evaluating the HRQoL of 178 non-selected UI patients referred for routine treatment at the Helsinki University Central Hospital between the years 2004 and 2010. HRQoL was assessed using the generic 15D questionnaire on four occasions: before treatment, 6 and 18 months after treatment, and after a median follow-up of 5 years. The HRQoL of the patients was compared with that of an age-standardized Finnish female population.

Results

Compared with the general population, the baseline total HRQoL score of the patients was significantly impaired (p < 0.001). It was worse among the urge or mixed (UUI (±SUI)) incontinence patients than among the stress incontinence (SUI) patients (p = 0.035). During follow-up, HRQoL improved and the improvement was more substantial among the operatively than among the conservatively treated patients (p = 0.027). Statistically significant improvement was only seen in the SUI group (Δ + 0.021, 95 % CI 0.005–0.036), but clinically relevant improvement was also found in the operatively treated UUI (±SUI) group. The maximum benefit of treatment was reached between at 2 and 3 years.

Conclusions

15D is a sensitive tool for monitoring the change in HRQoL and could be implemented into clinical practice. Operative treatment of UI is effective when measured by improved HRQoL. Not only SUI patients, but also selected patients with an urgency component may benefit from surgery.
Literatur
1.
Zurück zum Zitat Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardisation of terminology in lower urinary tract function: report from the Standardisation Sub-Committee of the International Continence Society. Neurourol Urodyn 21(2):167–178PubMedCrossRef Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2002) The standardisation of terminology in lower urinary tract function: report from the Standardisation Sub-Committee of the International Continence Society. Neurourol Urodyn 21(2):167–178PubMedCrossRef
2.
Zurück zum Zitat Minassian V, Drutz H, Al-Badr A (2003) Urinary incontinence as a worldwide problem. Int J Gynaecol Obstet 82:327–338PubMedCrossRef Minassian V, Drutz H, Al-Badr A (2003) Urinary incontinence as a worldwide problem. Int J Gynaecol Obstet 82:327–338PubMedCrossRef
3.
Zurück zum Zitat Sandvik H (1995) Female urinary incontinence: studies of epidemiology and management in general practice. Dissertation, Department of Public Health and Primary Health Care, University of Bergen Sandvik H (1995) Female urinary incontinence: studies of epidemiology and management in general practice. Dissertation, Department of Public Health and Primary Health Care, University of Bergen
4.
Zurück zum Zitat Botlero R, Urquhart DM, Davis SR, Bell RJ (2008) Prevalence and incidence of urinary incontinence in women: review of the literature and investigation of methodological issues. Int J Urol 15(3):230–234PubMedCrossRef Botlero R, Urquhart DM, Davis SR, Bell RJ (2008) Prevalence and incidence of urinary incontinence in women: review of the literature and investigation of methodological issues. Int J Urol 15(3):230–234PubMedCrossRef
5.
Zurück zum Zitat Saarni S, Härkänen T, Sintonen H et al (2006) The impact of 29 chronic conditions on health-related quality of life: a general population survey in Finland using 15D and EQ-5D. Qual Life Res 15:1403–1414PubMedCrossRef Saarni S, Härkänen T, Sintonen H et al (2006) The impact of 29 chronic conditions on health-related quality of life: a general population survey in Finland using 15D and EQ-5D. Qual Life Res 15:1403–1414PubMedCrossRef
6.
Zurück zum Zitat Stach-Lempinen B, Sintonen H, Kujansuu E (2004) The relationship between clinical parameters and health-related quality of life as measured by the 15D in incontinent women before and after treatment. Acta Obstet Gynecol Scand 83(10):983–988PubMed Stach-Lempinen B, Sintonen H, Kujansuu E (2004) The relationship between clinical parameters and health-related quality of life as measured by the 15D in incontinent women before and after treatment. Acta Obstet Gynecol Scand 83(10):983–988PubMed
7.
Zurück zum Zitat Ghoniem G, Stanford E, Kenton K, Achtari C, Goldberg R, Mascarenhas T et al (2008) Evaluation and outcome measures in the treatment of female urinary stress incontinence: International Urogynecological Association (IUGA) guidelines for research and clinical practice. Int Urogynecol J Pelvic Floor Dysfunct 19(1):5–33PubMedCentralPubMedCrossRef Ghoniem G, Stanford E, Kenton K, Achtari C, Goldberg R, Mascarenhas T et al (2008) Evaluation and outcome measures in the treatment of female urinary stress incontinence: International Urogynecological Association (IUGA) guidelines for research and clinical practice. Int Urogynecol J Pelvic Floor Dysfunct 19(1):5–33PubMedCentralPubMedCrossRef
8.
Zurück zum Zitat Shamliyan T, Wyman J, Kane R (2012) Nonsurgical treatments for urinary incontinence in adult women: Diagnosis and comparative effectiveness. comparative effectiveness review no. 36. AHRQ Publication 11(12)-EHC074-EF Shamliyan T, Wyman J, Kane R (2012) Nonsurgical treatments for urinary incontinence in adult women: Diagnosis and comparative effectiveness. comparative effectiveness review no. 36. AHRQ Publication 11(12)-EHC074-EF
9.
Zurück zum Zitat Ross S, Robert M, Lier D, Eliasziw M, Jacobs P (2011) Surgical management of stress urinary incontinence in women: Safety, effectiveness and cost-utility of trans-obturator tape (TOT) versus tension-free vaginal tape (TVT) five years after a randomized surgical trial. BMC Womens Health 11(1):34PubMedCentralPubMedCrossRef Ross S, Robert M, Lier D, Eliasziw M, Jacobs P (2011) Surgical management of stress urinary incontinence in women: Safety, effectiveness and cost-utility of trans-obturator tape (TOT) versus tension-free vaginal tape (TVT) five years after a randomized surgical trial. BMC Womens Health 11(1):34PubMedCentralPubMedCrossRef
10.
Zurück zum Zitat Jacklin P, Duckett J, Renganathan A (2010) Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence. Int Urogynecol J 21:977–984PubMedCrossRef Jacklin P, Duckett J, Renganathan A (2010) Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence. Int Urogynecol J 21:977–984PubMedCrossRef
11.
Zurück zum Zitat Palva K, Rinne K, Aukee P et al (2010) A randomized trial comparing tension-free vaginal tape with tension-free vaginal tape-obturator: 36-month results. Int Urogynecol J 21(9):1049–1055PubMedCrossRef Palva K, Rinne K, Aukee P et al (2010) A randomized trial comparing tension-free vaginal tape with tension-free vaginal tape-obturator: 36-month results. Int Urogynecol J 21(9):1049–1055PubMedCrossRef
12.
Zurück zum Zitat Sirls L, Tennstedt S, Lukacz E et al (2012) Condition-specific quality of life 24 months after retropubic and transobturator sling surgery for stress urinary incontinence. Female Pelvic Med Reconstr Surg 18(5):291–295PubMedCentralPubMedCrossRef Sirls L, Tennstedt S, Lukacz E et al (2012) Condition-specific quality of life 24 months after retropubic and transobturator sling surgery for stress urinary incontinence. Female Pelvic Med Reconstr Surg 18(5):291–295PubMedCentralPubMedCrossRef
13.
Zurück zum Zitat Kwon B, Kim G, Son Y, Roh Y, You M (2010) Quality of life of women with urinary incontinence: a systematic literature review. Int Neurourol J 14(3):133–138PubMedCentralPubMedCrossRef Kwon B, Kim G, Son Y, Roh Y, You M (2010) Quality of life of women with urinary incontinence: a systematic literature review. Int Neurourol J 14(3):133–138PubMedCentralPubMedCrossRef
15.
Zurück zum Zitat Sintonen H (2001) The 15D instrument of health-related quality of life: properties and applications. Ann Med 33:328–336PubMedCrossRef Sintonen H (2001) The 15D instrument of health-related quality of life: properties and applications. Ann Med 33:328–336PubMedCrossRef
17.
Zurück zum Zitat Sintonen H (1994) Outcome measurement in acid-related diseases. Pharmacoeconomics 5:17–26CrossRef Sintonen H (1994) Outcome measurement in acid-related diseases. Pharmacoeconomics 5:17–26CrossRef
18.
Zurück zum Zitat Alanne S (2011) Subjectively significant change in the measurement of health-related quality of life. Master’s Thesis, University of Eastern Finland Alanne S (2011) Subjectively significant change in the measurement of health-related quality of life. Master’s Thesis, University of Eastern Finland
19.
Zurück zum Zitat Aromaa A, Koskinen S (2004) Health and functional capacity in Finland. Baseline results of the Health 2000 Health Examination Survey. Publications of the National Public Health Institute. B12/2004 Aromaa A, Koskinen S (2004) Health and functional capacity in Finland. Baseline results of the Health 2000 Health Examination Survey. Publications of the National Public Health Institute. B12/2004
20.
Zurück zum Zitat Kauppila A, Alavaikko P, Kujansuu E (1982) Detrusor instability score in the evaluation of stress urinary incontinence. Acta Obstet Gynecol Scand 61(2):137–141PubMedCrossRef Kauppila A, Alavaikko P, Kujansuu E (1982) Detrusor instability score in the evaluation of stress urinary incontinence. Acta Obstet Gynecol Scand 61(2):137–141PubMedCrossRef
21.
Zurück zum Zitat Stach-Lempinen B, Hakala AL, Laippala P, Lehtinen K, Metsänoja R, Kujansuu E (2003) Severe depression determines quality of life in urinary incontinent women. Neurourol Urodyn 22(6):563–568PubMedCrossRef Stach-Lempinen B, Hakala AL, Laippala P, Lehtinen K, Metsänoja R, Kujansuu E (2003) Severe depression determines quality of life in urinary incontinent women. Neurourol Urodyn 22(6):563–568PubMedCrossRef
22.
Zurück zum Zitat Stach-Lempinen B, Kujansuu E, Laippala P, Metsänoja R (2001) Visual analogue scale, urinary incontinence severity score and 15 D—Psychometric testing of three different health-related quality-of-life instruments for urinary incontinent women. Scand J Urol Nephrol 35(6):476–483PubMedCrossRef Stach-Lempinen B, Kujansuu E, Laippala P, Metsänoja R (2001) Visual analogue scale, urinary incontinence severity score and 15 D—Psychometric testing of three different health-related quality-of-life instruments for urinary incontinent women. Scand J Urol Nephrol 35(6):476–483PubMedCrossRef
23.
Zurück zum Zitat Stach-Lempinen B, Kirkinen P, Laippala P, Metsänoja R, Kujansuu E (2004) Do objective urodynamic or clinical findings determine impact of urinary incontinence or its treatment on quality of life? Urology 63(1):67–71PubMedCrossRef Stach-Lempinen B, Kirkinen P, Laippala P, Metsänoja R, Kujansuu E (2004) Do objective urodynamic or clinical findings determine impact of urinary incontinence or its treatment on quality of life? Urology 63(1):67–71PubMedCrossRef
24.
Zurück zum Zitat Sintonen H (1994) The 15-D measure of health related quality of life: Reliability, validity and sensitivity of its health state descriptive system. Working Paper 41 CHPE Sintonen H (1994) The 15-D measure of health related quality of life: Reliability, validity and sensitivity of its health state descriptive system. Working Paper 41 CHPE
25.
Zurück zum Zitat Fairclough DL (2010) Design and analysis of quality of life studies in clinical trials. 2.th ed. Chapman & Hall/CRC Interdisciplinary Statistics Fairclough DL (2010) Design and analysis of quality of life studies in clinical trials. 2.th ed. Chapman & Hall/CRC Interdisciplinary Statistics
27.
28.
Zurück zum Zitat Hägglund D, Walker-Engström M, Larsson G, Leppert J (2001) Quality of life and seeking help in women with urinary incontinence. Acta Obstet Gynecol Scand 80(11):1051–1055PubMed Hägglund D, Walker-Engström M, Larsson G, Leppert J (2001) Quality of life and seeking help in women with urinary incontinence. Acta Obstet Gynecol Scand 80(11):1051–1055PubMed
29.
Zurück zum Zitat Nilsson C, Palva K, Rezapour M, Falconer C (2008) Eleven years prospective follow-up of the tension-free vaginal tape procedure for treatment of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 19(8):1043–1047PubMed Nilsson C, Palva K, Rezapour M, Falconer C (2008) Eleven years prospective follow-up of the tension-free vaginal tape procedure for treatment of stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct 19(8):1043–1047PubMed
30.
Zurück zum Zitat Palva K, Nilsson C (2011) Prevalence of urinary urgency symptoms decreases by mid-urethral sling procedures for treatment of stress incontinence. Int Urogynecol J 22(10):1241–1247PubMedCrossRef Palva K, Nilsson C (2011) Prevalence of urinary urgency symptoms decreases by mid-urethral sling procedures for treatment of stress incontinence. Int Urogynecol J 22(10):1241–1247PubMedCrossRef
Metadaten
Titel
The effectiveness of urinary incontinence treatments measured using the 15D Health-Related Quality of Life instrument
verfasst von
Aura Pyykönen
Pasi Aronen
Pirjo Räsänen
Risto P. Roine
Jari Sjöberg
Anna-Maija Tapper
Publikationsdatum
01.03.2014
Verlag
Springer London
Erschienen in
International Urogynecology Journal / Ausgabe 3/2014
Print ISSN: 0937-3462
Elektronische ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-013-2206-8

Weitere Artikel der Ausgabe 3/2014

International Urogynecology Journal 3/2014 Zur Ausgabe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

26.04.2024 Hirsutismus Nachrichten

Laser- und Lichtbehandlungen können bei Frauen mit polyzystischem Ovarialsyndrom (PCOS) den übermäßigen Haarwuchs verringern und das Wohlbefinden verbessern – bei alleiniger Anwendung oder in Kombination mit Medikamenten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bislang gibt es kein Medikament zur Prävention von Wochenbettdepressionen. Das Injektionsanästhetikum Esketamin könnte womöglich diese Lücke füllen.

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

22.04.2024 DGIM 2024 Kongressbericht

Durch die Häufung nach der COVID-19-Pandemie sind Infektionen mit dem Respiratorischen Synzytial-Virus (RSV) in den Fokus gerückt. Fachgesellschaften empfehlen eine Impfung inzwischen nicht nur für Säuglinge und Kleinkinder.

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.