Background
Methods
Subjects
Sample size calculation
Study design
Intervention
Physical activity counseling and real-time feedback
Usual care
Measurements
Physical activity
Lung function
Peripheral muscle strength
Functional exercise capacity
Questionnaires
Statistical analyses
Results
Baseline characteristics
Control group (N = 15) | Intervention group (N = 15) | P-value | |
---|---|---|---|
Demographic characteristics | |||
Age (years) | 68 ± 6 | 66 ± 7 | 0.34 |
BMI (kg/m2) | 29 ± 5 | 25 ± 9 | 0.20 |
Gender (male (N (%)) | 9 (60) | 8 (53) | 0.71 |
Pulmonary function | |||
FEV1 (% predicted) | 48 ± 18 | 38 ± 17 | 0.11 |
Tiffeneau Index (%) | 47 ± 13 | 41 ± 14 | 0.28 |
Peripheral muscle strength | |||
QF (Nm) | 112 ± 28 | 84 ± 42 | 0.05 |
QF (% predicted) | 85 ± 43 | 71 ± 38 | 0.38 |
Functional exercise capacity | |||
6MWD (meter) | 317 ± 95 | 235 ± 134 | 0.07 |
6MWD (% predicted) | 53 ± 16 | 36 ± 18 | 0.01 |
Stops during 6MWD (amount) | 0.66 ± 0.62 | 1.23 ± 0.92 | 0.15 |
Duration of stops (s) | 38 ± 48 | 81 ± 61 | 0.08 |
Physical activity | |||
PAsteps (amount/day) | 1557 ± 1319 | 1644 ± 2751 | 0.93 |
PAwalk (minutes/day) | 20 ± 17 | 22 ± 35 | 0.90 |
PAint (m/s2) | 1.34 ± 0.50 | 1.46 ± 0.25 | 0.50 |
Questionnaires | |||
mMRC (points) | 2 [2–3] | 3 [2–3] | 0.39 |
CAT (points) | 19 [15–22] | 25 [13–28] | 0.42 |
Drop out and follow-up completers
Change in physical activity during 1 month
Control group (N = 15) | Intervention group (N = 12) | |
---|---|---|
ΔPAsteps (amount/day) | ||
Time effect (p = 0.0005) | 1013 ± 1275 | 984 ± 1208 |
ΔPAwalk (minutes/day) | ||
Time effect (p = 0.0002) | 13 ± 14 | 13 ± 16 |
ΔPAint (m/s2/day) | ||
Time effect (p = 0.07) | 0.08 ± 0.06 | 0.06 ± 0.05 |
Change in clinical parameters during 1 month
Control group (N = 15) | Intervention group (N = 12) | P-value | |
---|---|---|---|
Muscle strength | |||
ΔQF (Nm) | 0.4 ± 20 | 5.3 ± 12 | 0.48 |
Functional exercise capacity | |||
Δ6MWD (meter) | 64 ± 59 | 67 ± 84 | 0.93 |
ΔStops during 6MWD (amount) | 0.08 ± 1.16 | 0.18 ± 1.08 | 0.84 |
ΔDuration of stops (s) | −14 ± 52 | −18 ± 57 | 0.86 |
Questionnaires | |||
ΔmMRC (points) | 0 [−1 to 0] | 0 [−1 to 0] | 0.93 |
ΔCAT (points) | −5 [−7 to 1] | −3 [−10 to 1] | 0.78 |