Skip to main content
Erschienen in: Clinical Autonomic Research 1/2020

01.12.2017 | Research Article

The hemodynamic and pain impact of peripheral nerve block versus spinal anesthesia in diabetic patients undergoing diabetic foot surgery

verfasst von: Hou Yee Lai, Li Lian Foo, Siu Min Lim, Chen Fei Yong, Pui San Loh, Sook Hui Chaw, Mohd Shahnaz Hasan, Chew Yin Wang

Erschienen in: Clinical Autonomic Research | Ausgabe 1/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Comparison of hemodynamic profiles and pain scores in diabetic patients undergoing diabetic foot surgery receiving peripheral nerve block (PNB) or spinal anesthesia [subarachnoid block (SAB)].

Methods

This was a prospective, randomised controlled trial. We recruited diabetic patients aged > 18 years, American Society of Anesthesiologists class II–III, who were scheduled for unilateral diabetic foot surgery below the knee. All patients were assessed for autonomic dysfunction using the Survey of Autonomic Symptoms score. Participants were randomly assigned to receive either PNB or SAB for the surgery. Hemodynamic data, including usage of vasopressors, were recorded at 5-min intervals for up to 1 h after the induction of anesthesia. Pain scores were recorded postoperatively, and follow-up was done via telephone 6 months later.

Results

Compared to the PNB group, the SAB group had a larger number of patients with significant hypotension (14 vs. 1; p = 0.001) and more patients who required vasopressor boluses (6 vs. 0 patients). Compared to SAB group, the patients in the PNB group had a longer postoperative pain-free duration (9 vs. 4.54 h; p = 0.002) and lower pain scores 1 day after surgery (3.63 vs. 4.69; p = 0.01).

Conclusion

Peripheral nerve block should be considered, whenever possible, as the first option of anesthesia for lower limb surgery in diabetic patients as it provides hemodynamic stability and superior postoperative pain control compared to SAB.

Trial registration

Clinical trial registry: ClinicalTrials.gov. ID NCT02727348.
Literatur
1.
Zurück zum Zitat Forouhi NGWN (2014) Epidemiology of diabetes. Medicine 42(12):698–702CrossRef Forouhi NGWN (2014) Epidemiology of diabetes. Medicine 42(12):698–702CrossRef
3.
Zurück zum Zitat Emerging Risk Factors C, Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J (2010) Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 375(9733):2215–2222. https://doi.org/10.1016/S0140-6736(10)60484-9 CrossRef Emerging Risk Factors C, Sarwar N, Gao P, Seshasai SR, Gobin R, Kaptoge S, Di Angelantonio E, Ingelsson E, Lawlor DA, Selvin E, Stampfer M, Stehouwer CD, Lewington S, Pennells L, Thompson A, Sattar N, White IR, Ray KK, Danesh J (2010) Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 375(9733):2215–2222. https://​doi.​org/​10.​1016/​S0140-6736(10)60484-9 CrossRef
4.
Zurück zum Zitat McAnulty GR, Robertshaw HJ, Hall GM (2000) Anaesthetic management of patients with diabetes mellitus. Br J Anaesth 85(1):80–90CrossRef McAnulty GR, Robertshaw HJ, Hall GM (2000) Anaesthetic management of patients with diabetes mellitus. Br J Anaesth 85(1):80–90CrossRef
5.
Zurück zum Zitat Simons LA, McCallum J, Friedlander Y, Simons J (1996) Diabetes, mortality and coronary heart disease in the prospective Dubbo study of Australian elderly. Aust N Z J Med 26(1):66–74CrossRef Simons LA, McCallum J, Friedlander Y, Simons J (1996) Diabetes, mortality and coronary heart disease in the prospective Dubbo study of Australian elderly. Aust N Z J Med 26(1):66–74CrossRef
6.
Zurück zum Zitat Aronson D, Rayfield EJ, Chesebro JH (1997) Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction. Ann Intern Med 126(4):296–306CrossRef Aronson D, Rayfield EJ, Chesebro JH (1997) Mechanisms determining course and outcome of diabetic patients who have had acute myocardial infarction. Ann Intern Med 126(4):296–306CrossRef
8.
Zurück zum Zitat Burgos LG, Ebert TJ, Asiddao C, Turner LA, Pattison CZ, Wang-Cheng R, Kampine JP (1989) Increased intraoperative cardiovascular morbidity in diabetics with autonomic neuropathy. Anesthesiology 70(4):591–597CrossRef Burgos LG, Ebert TJ, Asiddao C, Turner LA, Pattison CZ, Wang-Cheng R, Kampine JP (1989) Increased intraoperative cardiovascular morbidity in diabetics with autonomic neuropathy. Anesthesiology 70(4):591–597CrossRef
14.
Zurück zum Zitat Suarez GA, Opfer-Gehrking TL, Offord KP, Atkinson EJ, O’Brien PC, Low PA (1999) The autonomic symptom profile: a new instrument to assess autonomic symptoms. Neurology 52(3):523–528CrossRef Suarez GA, Opfer-Gehrking TL, Offord KP, Atkinson EJ, O’Brien PC, Low PA (1999) The autonomic symptom profile: a new instrument to assess autonomic symptoms. Neurology 52(3):523–528CrossRef
16.
Zurück zum Zitat Spallone V, Ziegler D, Freeman R, Bernardi L, Frontoni S, Pop-Busui R, Stevens M, Kempler P, Hilsted J, Tesfaye S, Low P, Valensi P, Toronto Consensus Panel on Diabetic N (2011) Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management. Diabetes Metab Res Rev 27(7):639–653. https://doi.org/10.1002/dmrr.1239 CrossRefPubMed Spallone V, Ziegler D, Freeman R, Bernardi L, Frontoni S, Pop-Busui R, Stevens M, Kempler P, Hilsted J, Tesfaye S, Low P, Valensi P, Toronto Consensus Panel on Diabetic N (2011) Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management. Diabetes Metab Res Rev 27(7):639–653. https://​doi.​org/​10.​1002/​dmrr.​1239 CrossRefPubMed
17.
Zurück zum Zitat Sampson MJ, Wilson S, Karagiannis P, Edmonds M, Watkins PJ (1990) Progression of diabetic autonomic neuropathy over a decade in insulin-dependent diabetics. Q J Med 75(278):635–646PubMed Sampson MJ, Wilson S, Karagiannis P, Edmonds M, Watkins PJ (1990) Progression of diabetic autonomic neuropathy over a decade in insulin-dependent diabetics. Q J Med 75(278):635–646PubMed
20.
Zurück zum Zitat Fanelli G, Casati A, Aldegheri G, Beccaria P, Berti M, Leoni A, Torri G (1998) Cardiovascular effects of two different regional anaesthetic techniques for unilateral leg surgery. Acta Anaesthesiol Scand 42(1):80–84CrossRef Fanelli G, Casati A, Aldegheri G, Beccaria P, Berti M, Leoni A, Torri G (1998) Cardiovascular effects of two different regional anaesthetic techniques for unilateral leg surgery. Acta Anaesthesiol Scand 42(1):80–84CrossRef
Metadaten
Titel
The hemodynamic and pain impact of peripheral nerve block versus spinal anesthesia in diabetic patients undergoing diabetic foot surgery
verfasst von
Hou Yee Lai
Li Lian Foo
Siu Min Lim
Chen Fei Yong
Pui San Loh
Sook Hui Chaw
Mohd Shahnaz Hasan
Chew Yin Wang
Publikationsdatum
01.12.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Clinical Autonomic Research / Ausgabe 1/2020
Print ISSN: 0959-9851
Elektronische ISSN: 1619-1560
DOI
https://doi.org/10.1007/s10286-017-0485-8

Weitere Artikel der Ausgabe 1/2020

Clinical Autonomic Research 1/2020 Zur Ausgabe

Neu in den Fachgebieten Neurologie und Psychiatrie

Chirurginnen und Chirurgen sind stark suizidgefährdet

07.05.2024 Suizid Nachrichten

Der belastende Arbeitsalltag wirkt sich negativ auf die psychische Gesundheit der Angehörigen ärztlicher Berufsgruppen aus. Chirurginnen und Chirurgen bilden da keine Ausnahme, im Gegenteil.

Ein Drittel der jungen Ärztinnen und Ärzte erwägt abzuwandern

07.05.2024 Medizinstudium Nachrichten

Extreme Arbeitsverdichtung und kaum Supervision: Dr. Andrea Martini, Sprecherin des Bündnisses Junge Ärztinnen und Ärzte (BJÄ) über den Frust des ärztlichen Nachwuchses und die Vorteile des Rucksack-Modells.

„Restriktion auf vier Wochen Therapie bei Schlaflosigkeit ist absurd!“

06.05.2024 Insomnie Nachrichten

Chronische Insomnie als eigenständiges Krankheitsbild ernst nehmen und adäquat nach dem aktuellen Forschungsstand behandeln: Das forderte der Schlafmediziner Dr. Dieter Kunz von der Berliner Charité beim Praxis Update.

Endlich: Zi zeigt, mit welchen PVS Praxen zufrieden sind

IT für Ärzte Nachrichten

Darauf haben viele Praxen gewartet: Das Zi hat eine Liste von Praxisverwaltungssystemen veröffentlicht, die von Nutzern positiv bewertet werden. Eine gute Grundlage für wechselwillige Ärztinnen und Psychotherapeuten.