Erschienen in:
16.04.2020 | Original Article
The impact of sedation on quality metrics of colonoscopy: a single-center experience of 48,838 procedures
verfasst von:
Song Zhao, Xiao-lian Deng, Li Wang, Jing-wang Ye, Zheng-yong Liu, Bin Huang, Ying Kan, Bao-hua Liu, An-ping Zhang, Chun-xue Li, Fan Li, Wei-dong Tong
Erschienen in:
International Journal of Colorectal Disease
|
Ausgabe 6/2020
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Abstract
Purpose
Investigation of the role of sedation during colonoscopy is meaningful as the advantages of colonoscopy performing with sedation are still controversial.
Methods
Medical records of patients who underwent colonoscopy in our institution were retrospectively analyzed. The sedation rate, adenoma detection rate (ADR), polyp detection rate (PDR), cecal intubation rate (CIR), iatrogenic colonic perforation rate (ICP) were calculated.
Results
A total of 48,838 colonoscopies (24,498 in males) dated from July 2007 to February 2017 were analyzed. The median age was 50 years (range 16–85 years). An overall sedation rate was 80.38%. The PDR was 26.77%, and was not statistically different between colonoscopy with or without sedation (26.67% vs 27.22, p = 0.474). ADR was 12.9% regardless of applying sedation or not (13.0% vs 12.44%, p = 0.337). The CIR was 87.42% in all examinations with an adjusted CIR of 90.34%, and was higher when performed with sedation than without sedation (88.92% vs 80.64%, p < 0.0001). Five cases (0.01%) of ICP were reported, all of which occurred in patients under sedation.
Conclusions
The use of sedation is associated with increased CIR, but ADR and PDR remain unchanged with or without sedation. However, perforation rate, albeit very low, is significantly higher in sedated patients.