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International Journal of Colorectal Disease

Clinical and Molecular Gastroenterology and Surgery

International Journal of Colorectal Disease OnlineFirst articles

26.11.2021 | Original Article Open Access

Prevalence of ‘pouch failure’ of the ileoanal pouch in ulcerative colitis: a systematic review and meta-analysis

Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is considered to be the gold standard surgical treatment for ulcerative colitis (UC) that is refractory to medical therapy [ 1 ]. Several iterations have been described in the …

24.11.2021 | Review Open Access

Endoscopic vacuum therapy for the treatment of colorectal leaks — a systematic review and meta-analysis

Since the first reported data in the late 1990s, vacuum-assisted wound therapy has captured nearly every field of surgery by providing a versatile and easy-to-handle method for complicated wounds [ 1 ]. In 2001, Weidenhagen et al. started to …

17.11.2021 | Original Article

Disease activity in inflammatory bowel disease patients is associated with increased liver fat content and liver fibrosis during follow-up

Non-alcoholic fatty liver disease (NAFLD), which is characterized by the presence of steatosis in >5% of the hepatocytes, is the most common cause of chronic liver disease [ 1 , 2 ]. NAFLD is considered a spectrum of liver disease starting with …

16.11.2021 | Original Article

How can we better identify patients with rectal bleeding who are at high risk of colorectal cancer? An observational study

Colorectal cancer is one of the most common malignancies affecting Canadians [ 1 ]. It is believed that the majority of colorectal carcinomas develop slowly, through the adenoma-carcinoma pathway, as described by Fearon and Vogelstein in 1990 [ 2 – …4

12.11.2021 | Original Article

Comparison of safety and efficacy of fluorouracil + oxaliplatin + irinotecan (FOLFOXIRI) and modified FOLFOXIRI with bevacizumab for metastatic colorectal cancer: data from clinical practice

In European countries, the efficacy of combined treatment with fluorouracil (5FU) + oxaliplatin (L-OHP) + irinotecan (IRI) with bevacizumab (FOLFOXIRI + BV) for metastatic colorectal cancer (mCRC) was examined in the TRIBE study and other …

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The International Journal of Colorectal Disease publishes novel and state-of-the-art papers dealing with the physiology and pathophysiology of diseases involving the gastrointestinal tract. In addition to original research articles of high scientific quality, the journal also publishes reviews and coverage of controversial issues in rapidly developing areas in gastroenterology and gastrointestinal surgery. The journal offers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.

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