Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Current Allergy and Asthma Reports
Erschienen in: Current Allergy and Asthma Reports 6/2010

01.11.2010

The Impact of Vaccination on Rhinosinusitis and Otitis Media

verfasst von: Michael S. Benninger, Ryan Manz

Erschienen in: Current Allergy and Asthma Reports | Ausgabe 6/2010

Einloggen, um Zugang zu erhalten

Abstract

Routine childhood vaccination has affected frequency and bacteriology of acute otitis media (AOM) and acute bacterial rhinosinusitis (ABRS). Routine influenza vaccination moderately reduces AOM, and the Haemophilus influenzae type b vaccine likely had a minor role in AOM and ABRS. The conjugated pneumococcal vaccine has drastically reduced invasive pneumococcal disease and caused a moderate decrease in AOM and, likely, ABRS. The vaccine serotypes of Streptococcus pneumoniae have been all but eliminated, but other serotypes have emerged as potential causes of invasive disease. Antibiotic resistance in pneumococcal disease seems to have decreased. A decrease in the overall prevalence of S. pneumoniae may have resulted in an increased incidence of Staphylococcus aureus as a pathogen in AOM and ABRS due to the concept of bacterial interference.
Literatur
1.
Benninger MS, Ferguson BJ, Hadley JA, et al.: Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 2003, 129:S1–S32.CrossRefPubMed
2.
Anon JB, Jacobs MR, Poole MD, et al.: Antimicrobial treatment guidelines for acute bacterial rhinosinusitis. Otolaryngol Head Neck Surg 2004, 130:1–45.PubMed
3.
• Payne SC, Benninger MS: Staphylococcus aureus is a major pathogen in acute bacterial rhinosinusitis: a meta-analysis. J Clin Infect Dis 2007, 45:e121–e127. This study is a comprehensive meta-analysis showing that S. aureus is a true pathogen in ABRS.CrossRef
4.
Benninger MS: Acute bacterial rhinosinusitis and otitis media: changes in pathogenicity following widespread use of pneumococcal conjugate vaccine. Otolaryngol Head Neck Surg 2008, 138:274–278.CrossRefPubMed
5.
Paradise JL, Rockette HE, Colborn DK, et al.: Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life. Pediatrics 1997, 99:318–333.CrossRefPubMed
6.
Block SL, Hedrick J, Harrison CJ, et al.: Community-wide vaccination with the heptavalent pneumococcal conjugate significantly alters the microbiology of acute otitis media. Pediatr Infect Dis 2004, 23:829–833.CrossRef
7.
Sahm DF, Benninger MS, Evangelista AT, et al.: Antimicrobial resistance trends among sinus isolates of Streptococcus pneumoniae from the United States: 2000–2005. Otolaryngol Head Neck Surg 2007, 136:385–389.CrossRefPubMed
8.
Pichichero ME, Casey JR, Hoberman A, et al.: Pathogens causing recurrent and difficult-to-treat acute otitis media 2003–2006. Clin Pediatr (Phila) 2008, 47:901–906.CrossRef
9.
Centers for Disease Control and Prevention: Progress toward elimination of Haemophilus influenza type b invasive disease among infants and children—United States, 1998–2000. MMWR Morb Mortal Wkly Rep 2002, 51:234–237.
10.
O’Brien KL, Wolfson LJ, Watt JP, et al.: Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet 2009, 374:893–902.CrossRefPubMed
11.
Black S, Shinefield H, Fireman B, et al.: Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Pediatr Infect Dis 2000, 19:187–195.CrossRef
12.
Shafinoori S, Ginocchio CC, Greenberg AJ, et al.: Impact of pneumococcal conjugate vaccine and the severity of winter influenza-like illnesses on invasive pneumococcal infections in children and adults. Pediatr Infect Dis 2005, 24:10–16.CrossRef
13.
Whitney CG, Farley MM, Hadler J, et al.: Decline in invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N Engl J Med 2003, 348:1737–1746.CrossRefPubMed
14.
Hsu HE, Shutt KA, Moore MR, et al.: Effect of pneumococcal conjugate vaccine on pneumococcal meningitis. N Engl J Med 2009, 360:244–256.CrossRefPubMed
15.
Tsigrelis C, Tleyjeh IM, Lahr BD, et al.: Decreases in case-fatality and mortality rates for invasive pneumococcal disease in Olmsted County, Minnesota, during 1995–2007: a population-based study. Clin Infect Dis 2008, 47:1367–1371.CrossRefPubMed
16.
Eskola J, Kilpi T, Palmu A, et al.: Efficacy of a pneumococcal conjugate vaccine against acute otitis media. N Engl J Med 2001, 344:403–409.CrossRefPubMed
17.
Palmu A, Verho J, Jokenen J: The seven-valent pneumococcal conjugate vaccine reduces tympanostomy tube placement in children. Pediatr Infect Dis J 2004, 23:732–738.CrossRefPubMed
18.
Fireman B, Black SB, Shinefield HR, et al.: Impact of pneumococcal conjugate vaccine on otitis media. Pediatr Infect Dis 2003, 22:10–16.CrossRef
19.
Jardine A, Menzies R, Deeks S: The impact of pneumococcal conjugate vaccine on rates of myringotomy with ventilation tube insertion in Australia. Pediatr Infect Dis J 2009, 9:761–765.
20.
Poehling K, Szilagyi P, Grijalva C, et al.: Reduction in frequent otitis media and pressure equalizing tube insertions after introduction of pneumococcal conjugate vaccine. Pediatrics 2007, 119:1394–1402.CrossRef
21.
•• Jansen AG, Hak E, Veenhoven RH, et al.: Pneumococcal vaccines for preventing otitis media. Cochrane Database Sys Rev 2009, 2:CD001480. This Cochrane Database review provides a comprehensive literature review of the effects of pneumococcal vaccines on the rate of AOM.
22.
Reinert P: The role of pneumococcal and haemophilus type B vaccination in the prevention of acute otitis media. Clin Microbiol Infect 1997, 3:S59–S61.CrossRefPubMed
23.
Klein J: Role of nontypeable Haemophilus influenzae in pediatric respiratory tract infections. Pediatr Infect Dis J 1997, 16:S5–S8.CrossRefPubMed
24.
•• Manzoli L, Schioppa F, Boccia A, et al.: The efficacy of influenza vaccine for healthy children: a meta-analysis evaluating potential sources of variation in efficacy estimates including study quality. Pediatr Infect Dis J 2007, 26:97–106. This meta-analysis provides a comprehensive and complete study of the randomized controlled trials evaluating the effects of the influenza vaccine on AOM.CrossRefPubMed
25.
Benninger MS, Sedory Holzer SE, Lau J: Diagnosis and treatment of uncomplicated acute bacterial rhinosinusitis: summary of the Agency for Health Care Policy and Research evidence-based report. Otolaryngol Head Neck Surg 2000, 122:1–7.CrossRefPubMed
26.
Pichichero ME, Brixner DI: A review of recommended antibiotic therapy with impact on outcomes in acute otitis media and acute bacterial sinusitis. Am J Manag Care 2006, 12:S292–S302.PubMed
27.
American Academy of Pediatrics, Subcommittee on Management of Sinusitis and Committee on Quality Improvement: Clinical practice guideline: management of sinusitis. Pediatrics 2001, 108:798–808.
28.
Benninger MS, Brook I, Farrell DJ: Disease severity in acute bacterial rhinosinusitis is greater in patients infected with Streptococcus pneumoniae than in those infected with Haemophilus influenzae. Otolaryngol Head Neck Surg 2006, 135:523–528.CrossRefPubMed
29.
Brook I, Foote PA, Hausfeld JN: Frequency of recovery of pathogens causing acute maxillary sinusitis in adults before and after introduction of vaccination of children with the 7-valent vaccine. J Med Microbiol 2006, 55:943–946.CrossRefPubMed
30.
Brook I, Gober A: Bacteriology of spontaneously draining acute otitis media in children before and after the introduction of pneumococcal vaccination. Pediatr Infect Dis J 2009, 7:640–642.
31.
Ambati BK, Ambati J, Azar N, et al.: Periorbital and orbital cellulitis before and after the advent of Haemophilus influenza type B vaccine. Ophthalmology 2000, 107:1450–1453.CrossRefPubMed
32.
Casey JR, Pichichero ME: Changes in frequency and pathogens causing acute otitis media in 1995–2003. Pediatr Infect Dis J 2004, 23:824–828.CrossRefPubMed
33.
• Brook I, Gober AE: Frequency of recovery of pathogens from the nasopharynx of children with acute maxillary sinusitis before and after the introduction of vaccination with the 7-valent pneumococcal vaccine. Int J Pediatr Otorhinolaryngol 2007, 71:575–579. This study provides one of the best examples of changes in bacteriology before and after widespread use of the PCNV7 vaccine.CrossRefPubMed
34.
Kilpi T, Ahman H, Jokinen J, et al.: Protective efficacy of a second pneumococcal conjugate vaccine against pneumococcal otitis media in infants and children: randomized, controlled trial of a 7-valent pneumococcal polysaccharide-meningococcal outer membrane protein complex conjugate vaccine in 1666 children. Clin Infect Dis 2003, 37:1155–1164.CrossRefPubMed
35.
Casey JR, Adlowitz D, Pichichero M: New patterns in the otopathogens causing acute otitis media six to eight years after introduction of pneumococcal conjugate vaccine. Pediatr Infect Dis J 2010, 29:304–309.PubMed
36.
Hanage WP, Auranen K, Syrjanen R, et al.: Ability of pneumococcal serotypes and clones to cause acute otitis media: implications for the prevention of otitis media by conjugate vaccines. Infect Immun 2004, 72:76–81.CrossRefPubMed
37.
• Singleton RJ, Hennessy TW, Bulkow LR, et al.: Invasive pneumococcal disease caused by nonvaccine serotypes among Alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage. JAMA 2007, 297:1784–1792. This was one of the longest population-based longitudinal studies of invasive pneumococcal disease.CrossRefPubMed
38.
Jacobs MR, Good CE, Sellner T, et al.: Nasopharyngeal carriage of respiratory pathogens in children undergoing pressure equalization tube placement in the era of pneumococcal protein conjugate vaccine use. Laryngoscope 2007, 117:295–298.CrossRefPubMed
39.
Ongkasuwan J, Valdez TA, Hulten KG, et al.: Pneumococcal mastoiditis in children and the emergence of multidrug-resistant serotype 19A isolates. Pediatrics 2008, 122:34–39.CrossRefPubMed
40.
McNeil JC, Hulten KG, Mason EO Jr, et al.: Serotype 19A is the most common Streptococcus pneumoniae isolate in children with chronic sinusitis. Pediatr Infect Dis J 2009, 28:766–768.CrossRefPubMed
41.
Regev-Yochay G, Dagan R, Raz M, et al.: Association between carriage of Streptococcus pneumoniae and Staphylococcus aureus in children. JAMA 2004, 292:716–720.CrossRefPubMed
42.
Bogaert D, van Belkum A, Sluijter M, et al.: Colonization by Streptococcus pneumoniae and Staphylococcus aureus in healthy children. Lancet 2004, 363:1871–1872.CrossRefPubMed
43.
Brook I: The role of bacterial interference in otitis, sinusitis and tonsillitis. Otolaryngol Head Neck Surg 2005, 133:139–146.CrossRefPubMed
44.
Roos K, Hakansson EG, Holm S: Effect of recolonisation with “interfering” alpha streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial. BMJ 2001, 322:210–212.CrossRefPubMed
45.
Rautava S, Salminen S, Isolauri E: Specific probiotics in reducing the risk of acute infections in infancy—a randomised, double-blind, placebo-controlled study. Br J Nutr 2009, 11:1722–1726.CrossRef
46.
Black S, Shinefield H, Baxter R, et al.: Postlicensure surveillance for pneumococcal invasive disease after use of heptavalent pneumococcal conjugate vaccine in northern California Kaiser Permanente. Pedatr Infect Dis 2004, 23:485–489.CrossRef
47.
Park SY, Moore MR, Bruden DL, et al.: Impact of conjugate vaccine on transmission of antimicrobial-resistant Streptococcus pneumoniae among Alaskan children. Pediatr Infect Dis J 2008, 27:335–340.CrossRefPubMed
48.
Garbutt J, Rosenbloom I, Wu J, Storch GA: Empiric first-line antibiotic treatment of acute otitis in the era of the heptavalent pneumococcal conjugate vaccine. Pediatrics 2006, 117:e1087–e1094.CrossRefPubMed
49.
Huang SS, Platt R, Rifas-Shiman SL, et al.: Post-PCV7 changes in colonizing pneumococcal serotypes in 16 Massachusetts communities, 2001 and 2004. Pediatrics 2005, 116:e408–e413.CrossRefPubMed
50.
Kyaw MH, Lynfield R, Schaffner W, et al.: Effect of introduction of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae. N Engl J Med 2006, 354:1455–1463.CrossRefPubMed
Metadaten
Titel
The Impact of Vaccination on Rhinosinusitis and Otitis Media
verfasst von
Michael S. Benninger
Ryan Manz
Publikationsdatum
01.11.2010
Verlag
Current Science Inc.
Erschienen in
Current Allergy and Asthma Reports / Ausgabe 6/2010
Print ISSN: 1529-7322
Elektronische ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-010-0139-6

Weitere Artikel der Ausgabe 6/2010

Current Allergy and Asthma Reports 6/2010 Zur Ausgabe

ReviewPaper

The Hygiene Hypothesis Revisited: Role of Materno-Fetal Interactions

ReviewPaper

Pediatric Pay-for-performance in Asthma: Who Pays?

ReviewPaper

Otitis Media in Children with Congenital Immunodeficiencies

ReviewPaper

Fetal Epigenetic Mechanisms and Innate Immunity in Asthma

Clinical Trial Report

Vitamin D Insufficiency and Risk of Severe Asthma Exacerbations

ReviewPaper

Role of Adenoidectomy in Otitis Media and Respiratory Function

Neu im Fachgebiet HNO

16.04.2024 | HNO-Chirurgie | Nachrichten

HNO-Op. auch mit über 90?

16.04.2024 | Tonsillektomie | Nachrichten

Intrakapsuläre Tonsillektomie gewinnt an Boden

15.04.2024 | Hörsturz | Nachrichten

Bilateraler Hörsturz hat eine schlechte Prognose

13.04.2024 | Klinik aktuell | Kongressbericht | Nachrichten

„Nur wer sich gut aufgehoben fühlt, kann auch für Patientensicherheit sorgen“
weitere anzeigen

Update HNO

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen