nach oben

European Journal of Applied Physiology

Erschienen in:

01.11.2008 | Original Article

The influence of increased training volume on cytokines and ghrelin concentration in college level male rowers

verfasst von: Raul Rämson, Jaak Jürimäe, Toivo Jürimäe, Jarek Mäestu

Erschienen in: European Journal of Applied Physiology | Ausgabe 5/2008

Einloggen, um Zugang zu erhalten

Abstract

The aim of this study was to investigate plasma IL-6, TNF-α, leptin and ghrelin concentrations during high-volume training. Eight trained male rowers participated. Fasting blood was sampled before (T1) and after (T2) increased training volume and after recovery period (T3). Two-hour rowing was performed at T1, T2 and at T3 with blood samples before, POST and POST 30′. Decrease in fasting leptin was observed at T2 (from 1.31 (0.53) to 0.93 (0.27) ng ml⁻¹; P < 0.05). Leptin was also significantly decreased at POST and POST 30 exercise compared to PRE test at T2. At T2 POST 30′ leptin was significantly lower compared to corresponding value at T1. There were no significant post-exercise changes in ghrelin at T2 compared to T1 and T3. TNF-α was significantly increased POST exercise only at T2. In conclusion, high-volume training causes alterations of post exercise leptin and TNF-α, while increases in ghrelin are down regulated.

Ariyasu H, Takaya K, Tagami T, Ogawa Y, Hosoda K, Akamizu T et al (2001) Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 86:4753–4758. doi:10.1210/jc.86.10.4753 PubMedCrossRef

Bouchard C, Tremblay A, Leblanc C, Lortie G, Savard R, Thériault G (1983) A method to assess energy expenditure in children and adults. Am J Clin Nutr 37:461–467PubMed

Christ ER, Zehnder M, Boesch C, Trepp R, Mullis PE, Diem P et al (2006) The effect of increased lipid intake on hormonal responses during aerobic exercise in endurance-trained men. J Clin Endocrinol 154:397–403

Coppack SW (2001) Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 60:349–356PubMedCrossRef

Desgorces FD, Chennaoui M, Gomez-Merino D, Drogou C, Guezennec CY (2004) Leptin response to acute prolonged exercise after training in rowers. Eur J Appl Physiol 91:677–681. doi:10.1007/s00421-003-1030-0 PubMedCrossRef

Dill DB, Costill DL (1974) Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 37:247–248PubMed

Fantuzzi G (2005) Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 115:911–919. doi:10.1016/j.jaci.2005.02.023 PubMedCrossRef

Foster-Schubert KE, McTiernan A, Scott Frayo R, Schwartz RS, Rajan KB, Yasui Y et al (2005) Human plasma levels of ghrelin increase during a one-year exercise program. J Clin Endocrinol Metab 90:820–825. doi:10.1210/jc.2004-2081 PubMedCrossRef

Gaillard RC, Spinedi E, Chautard T, Pralong FP (2000) Cytokines, leptin, and the hypothalamo-pituitary-adrenal axis. Ann N Y Acad Sci 917:646–647

Hansen TK, Dall R, Hoshoda H, Kojima M, Kangawa K, Christiansen JS et al (2002) Weight loss increases circulating levels of ghrelin in human obesity. Clin Endocrinol (Oxf) 56:203–206. doi:10.1046/j.0300-0664.2001.01456.x CrossRef

Henson DA, Nieman DC, Nehlsen-Cannarella SL, Fagoaga OR, Shannon M, Bolton MR et al (2000) Influence of carbohydrate on cytokine and phagocytic responses to 2 h of rowing. Med Sci Sports Exerc 32:1384–1389. doi:10.1097/00005768-200008000-00005 PubMedCrossRef

Hofmann P, Jurimae J, Jurimae T, Maestu J, Purge P, Pokan R et al (2007) HRTP, prolonged ergometer exercise and single sculling. Int J Sports Med 28:964–969. doi:10.1055/s-2007-965074 PubMedCrossRef

Jurimae J, Maestu J, Purge P, Soot T, Jurimae T (2002) Relations among heavy training stress, mood state, and performance for male junior rowers. Percept Mot Skills 95:520–526PubMed

Jurimae J, Maestu J, Jurimae T (2003) Leptin as a marker of training stress in highly trained male rowers. Eur J Appl Physiol 90:533–538. doi:10.1007/s00421-003-0879-2 PubMedCrossRef

Jurimae J, Hofmann P, Jurimae T, Palm R, Maestu J, Purge P et al (2007) Plasma ghrelin responses to acute sculling exercises in elite male rowers. Eur J Appl Physiol 99:467–474. doi:10.1007/s00421-006-0370-y PubMedCrossRef

Kallio J, Pesonen U, Karvonen MK, Kojima M, Hosoda H, Kangawa K et al (2001) Enhanced exercise-induced GH secretion in subjects with Pro7 substitutionin the Prepro-NPY. J Clin Endocrinol Metab 86:5348–5352. doi:10.1210/jc.86.11.5348 PubMedCrossRef

Kellmann M, Kallus KW (2001) Recovery-stress questionnaire for athletes. User manual. Human kinetics. Champaign, IL

Kraemer RR, Durand RJ, Acevedo EO, Johnson LG, Kraemer GR, Hebert EP et al (2004) Rigorous running increases growth hormone and insulin-like growth factor-I without altering ghrelin. Exp Biol Med 229:240–246

Maestu J, Jurimae J, Jurimae T (2003) Effect of heavy increase in training stress on the plasma level of leptin concentration in highly trained male rowers. Horm Res 59:91–94PubMedCrossRef

Maestu J, Jurimae J, Jurimae T (2005) Monitoring of performance and training in rowing. Sports Med 25:597–617. doi:10.2165/00007256-200535070-00005 CrossRef

Maestu J, Jurimae J, Kreegipuu K, Jurimae T (2006) Changes in Perceived stress and recovery during heavy training in highly trained male rowers. Sport Psychol 20:24–39

Maestu J, Jurimae J, Valter I, Jurimae T (2008) Increases in ghrelin and decreases in leptin without altering adiponectin during extreme weight loss in male competitive bodybuilders. Metabol 57:221–225. doi:10.1016/j.metabol.2007.09.004 CrossRef

Meeusen R, Piacentini MF, Busschaert B, Buyse L, De Schutter G, Stray-Gundersen J (2004) Hormonal responses in athletes: the use of a two bout exercise protocol to detect subtle differences in (over)training status. Eur J Appl Physiol 91:140–146. doi:10.1007/s00421-003-0940-1 PubMedCrossRef

Nehlsen-Cannarella SL, Fagoaga OR, Nieman DC, Henson DA, Butterworth DE, Schmitt RL et al (1997) Carbohydrate and the cytokine response to 2, 5 hours of running. J Appl Physiol 82:1662–1667PubMed

Nindl BC, Kraemer WJ, Arciero PJ, Samatallee N, Leone C, Mayo M et al (2002) Leptin concentrations experience a delayed reduction after resistance exercise in men. Med Sci Sports Exerc 34:608–613. doi:10.1097/00005768-200204000-00008 PubMedCrossRef

Noland RC, Baker JT, Boudreau SR, Kobe RW (2001) Effect of intense training on plasma leptin in male and female swimmers. Med Sci Sports Exerc 33:227–231. doi:10.1097/00005768-200102000-00009 PubMed

Ostrowski K, Rohde T, Asp S, Schjerling P, Pedersen BK (1999) Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol 515:287–291. doi:10.1111/j.1469-7793.1999.287ad.x PubMedCrossRef

Pedersen BK, Ostrowski K, Rohde T, Bruunsgaard H (1998) The cytokine response to strenuous exercise. Can J Physiol Pharmacol 76:505–511. doi:10.1139/cjpp-76-5-505 PubMedCrossRef

Raglin JS, Morgan WP, O’Conner PJ (1991) Changes in mood state responses during training in female and male college swimmers. Int J Sports Med 12:585–589PubMed

Robson-Ansley PJ, Blannin A, Gleeson M (2007) Elevated plasma interleukin-6 levels in trained male triathletes following an acute period of intense interval training. Eur J Appl Physiol 99:353–360. doi:10.1007/s00421-006-0354-y PubMedCrossRef

Simsch C, Lormes W, Petersen KG, Baur S, Liu Y, Hackney AC et al (2002) Training influences leptin and thyroid hormones in highly trained rowers. Int J Sports Med 23:442–447. doi:10.1055/s-2002-33738 CrossRef

Smith LL (2000) Cytokine hypothesis to overtraining: a physiological adaptation to excessive stress? Med Sci Sports Exerc 32:317–331. doi:10.1097/00005768-200002000-00011 PubMedCrossRef

Starkie RL, Arkinstall MJ, Koukolas I, Hawley J, Febbraio M (2001) Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans. J Physiol 533:585–591. doi:10.1111/j.1469-7793.2001.0585a.x PubMedCrossRef

Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, Klarlund PB (2000) Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 529:237–242. doi:10.1111/j.1469-7793.2000.00237.x PubMedCrossRef

Steensberg A, van Hall G, Osada T, Schjerling P, Sacchetti M, Saltin B et al (2001) Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content. J Physiol 537:633–639. doi:10.1111/j.1469-7793.2001.00633.x PubMedCrossRef

Steinacker JM, Lormes W, Kellmann M (2000) Training of junior rowers before world champinochips: effects on performance, mood state and selected hormonal and metabolic responses. J Sports Med Phys Fitness 40:327–335PubMed

Steinacker JM, Lormes W, Reissnecker S, Liu Y (2004) New aspects of the hormone and cytokine responses to training. Eur J Appl Physiol 91:382–391. doi:10.1007/s00421-003-0960-x PubMedCrossRef

Stewart LK, Flynn MG, Campell WW, Craig BA, Robinson JP, Timmermann KL et al (2007) The influence of exercise training on inflammatory cytokines and C-reactive protein. Med Sci Sports Exerc 39:1714–1719PubMed

Urhausen A, Kindermann W (2002) Diagnosis of overtraining. What tools do we have? Sports Med 32:95–102. doi:10.2165/00007256-200232020-00002 PubMedCrossRef

Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG et al (2001) Ghrelin enchances appetite and increases food intake in humans. J Clin Endocrinol Metab 86:4992–4995. doi:10.1210/jc.86.12.5992 CrossRef

Zaccaria M, Ermolao A, Roi GS, Englaro P, Tegon G, Varnier M (2002) Leptin reduction after endurance races differing in duration and energy expenditure. Eur J Appl Physiol 7:108–111. doi:10.1007/s00421-002-0606-4 CrossRef

Titel: The influence of increased training volume on cytokines and ghrelin concentration in college level male rowers
verfasst von: Raul Rämson
Jaak Jürimäe
Toivo Jürimäe
Jarek Mäestu
Publikationsdatum: 01.11.2008
Verlag: Springer-Verlag
Erschienen in: European Journal of Applied Physiology / Ausgabe 5/2008
Print ISSN: 1439-6319
Elektronische ISSN: 1439-6327
DOI: https://doi.org/10.1007/s00421-008-0839-y

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Open Access ADHS Leitthema

Die Aufmerksamkeitsdefizit‑/Hyperaktivitätsstörung (ADHS) ist eine der häufigsten psychischen Störungen im Kindes- und Jugendalter [ 1 ]. In Deutschland beträgt die Prävalenz einer elternberichteten ADHS-Diagnose bei Kindern und Jugendlichen 4,4 % …

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Open Access Leitthema

Die Begrenzung von Schäden durch Substanzkonsum und andere abhängige Verhaltensweisen von Jugendlichen und jungen Erwachsenen ist ein wichtiges Anliegen der öffentlichen Gesundheit. Der Übergang von der Adoleszenz zum jungen Erwachsenenalter ist …

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Leitthema

In der Öffentlichkeit wird die berufliche Ausbildung oftmals unter ökonomischen Gesichtspunkten diskutiert: Mit den geburtenstarken Jahrgängen gehen erfahrene Fachkräfte in Rente und von nachfolgenden Generationen rücken zu wenige Arbeitskräfte …

Rauschtrinken in der frühen Adoleszenz

COVID-19 Leitthema

Alkohol ist in Deutschland die mit Abstand am häufigsten konsumierte psychoaktive Substanz. Mehr als 2 Drittel aller Erwachsenen im Alter von 18 bis 64 Jahren (70,5 %) hat 2021 in den letzten 30 Tagen Alkohol konsumiert [ 1 ]. Von diesen …

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 5/2008

Increased nitric oxide synthase activity and Hsp90 association in skeletal muscle following chronic exercise

No effect of carbohydrate feeding on 16 km cycling time trial performance

Changes in oxygen consumption of human muscle and tendon following repeat muscle contractions

Long-term resistance training improves force and unloaded shortening velocity of single muscle fibres of elderly women

Sex-related differences in evaporative heat loss: the importance of metabolic heat production

Power spectra characteristics associated with static reflexive activation of the multifidus muscle in feline models

Neu im Fachgebiet Arbeitsmedizin

Elterliches Belastungserleben, Unaufmerksamkeits‑/Hyperaktivitätssymptome und elternberichtete ADHS bei Kindern und Jugendlichen: Ergebnisse aus der KiGGS-Studie

Substanzkonsum und Nutzung von sozialen Medien, Computerspielen und Glücksspielen unter Auszubildenden an beruflichen Schulen

Berufsbelastung und Stressbewältigung von weiblichen und männlichen Auszubildenden

Rauschtrinken in der frühen Adoleszenz