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AIDS and Behavior

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28.08.2019 | Substantive Review

The PrEP Care Continuum and Black Men Who Have Sex with Men: A Scoping Review of Published Data on Awareness, Uptake, Adherence, and Retention in PrEP Care

verfasst von: Ogochukwu Ezennia, Angelica Geter, Dawn K. Smith

Erschienen in: AIDS and Behavior | Ausgabe 10/2019

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Abstract

Pre-exposure prophylaxis (PrEP) has demonstrated high efficacy to reduce HIV infections, however, racial/ethnic HIV disparities continue among black MSM. The purpose of this review was to assess available data to inform interventions to increase PrEP awareness, uptake, and adherence among black MSM. Of the 3024 studies retrieved, 36 met final inclusion criteria and were categorized into the PrEP care continuum: (1) awareness (n = 16), (2) uptake (n = 9), and (3) adherence (n = 12). Only 26 of the studies presented analytical findings by race/ethnicity. Key barrier themes included cost, HIV-related stigma, and fear of potential side effects. A key facilitator theme identified by black MSM included gaining PrEP awareness from social and sexual networks. There are significant gaps in research on black MSM and PrEP utilization, especially regarding PrEP uptake and adherence. These data are needed to inform interventions to address current inequities in PrEP services, to help improve care outcomes for black MSM.

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Centers of Disease Control and Prevention. Diagnoses of HIV Infection in the United States and Dependent Areas, 2017 2018. http://www.cdc.gov/hiv/pdf/library/reports/surveillance/cdc-hiv-surveillance-report-2017-vol-29.pdf. Accessed 30 Jun 2019.

Centers for Disease Control and Prevention. HIV Surveillance Report, 2017 2018. http://cdc.gov/hiv/library/reports/hiv-surveillance.html. Accessed 30 Jun 2019.

HIV.gov. National HIV/AIDS Strategy: Updated to 2020 2017. https://www.hiv.gov/federal-response/national-hiv-aids-strategy/nhas-update. Accessed 30 Jun 2019.

Centers for Disease Control and Prevention. HIV Basics: PrEP 2017. http://www.cdc.gov/hiv/basics/prep.html. Accessed 30 Jun 2019.

Bush S, Magnuson D, Rawlings MK, Hawkins T, McCallister S, Mera Giler R. Racial characteristics of FTC/TDF for pre-exposure prophylaxis (PrEP) users in the US. American Society for Microbiology 2016; 2016 June 16–20, 2016; Boston, MA.

Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. NEJM. 2010;363(27):2587–99.PubMedCrossRef

Grant RM, Anderson PL, McMahan V, Liu A, Amico KR, Mehrotra M, et al. Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: a cohort study. Lancet Infect Dis. 2014;14(9):820–9.PubMedPubMedCentralCrossRef

Grohskopf LA, Chillag KL, Gvetadze R, Liu AY, Thompson M, Mayer KH, et al. Randomized trial of clinical safety of daily oral tenofovir disoproxil fumarate among HIV-uninfected men who have sex with men in the United States. J Acquir Immune Defic Syndr. 2013;64(1):79–86.PubMedCrossRef

Liu AY, Cohen SE, Vittinghoff E, Anderson PL, Doblecki-Lewis S, Bacon O, et al. Preexposure prophylaxis for HIV infection integrated with municipal- and community-based sexual health services. JAMA Intern Med. 2016;176(1):75–84.PubMedPubMedCentralCrossRef

10.

Marcus JL, Hurley LB, Hare CB, Silverberg MJ, Volk JE. Disparities in uptake of HIV preexposure prophylaxis in a large integrated health care system. AJPH. 2016;106(10):e2–3.CrossRef

11.

Parsons JT, Rendina HJ, Lassiter JM, Whitfield THF, Starks TJ, Grov C. Uptake of HIV pre-exposure prophylaxis (PrEP) in a National Cohort of Gay and Bisexual Men in the United States. J Acquir Immune Defic Syndr. 2017;74(3):285–92.PubMedPubMedCentralCrossRef

12.

Chan PA, Mena L, Patel R, Oldenburg CE, Beauchamps L, Perez-Brumer AG, et al. Retention in care outcomes for HIV pre-exposure prophylaxis implementation programmes among men who have sex with men in three US cities. J Int AIDS Soc. 2016;19(1):20903.PubMedPubMedCentralCrossRef

13.

Hosek SG, Siberry G, Bell M, Lally M, Kapogiannis B, Green K, et al. The acceptability and feasibility of an HIV preexposure prophylaxis (PrEP) trial with young men who have sex with men. J Acquir Immune Defic Syndr. 2013;62(4):447–56.PubMedCrossRef

14.

Hosek SG, Rudy B, Landovitz R, Kapogiannis B, Siberry G, Rutledge B, et al. An HIV preexposure prophylaxis demonstration project and safety study for young MSM. J Acquir Immune Defic Syndr. 2017;74(1):21–9.PubMedPubMedCentralCrossRef

15.

Hosek SG, Landovitz RJ, Kapogiannis B, Siberry GK, Rudy B, Rutledge B, et al. Safety and feasibility of antiretroviral preexposure prophylaxis for adolescent men who have sex with men aged 15 to 17 years in the United States. JAMA Pediatr. 2017;171(11):1063–71.PubMedPubMedCentralCrossRef

16.

Scott HM, Pollack L, Rebchook GM, Huebner DM, Peterson J, Kegeles SM. Peer social support is associated with recent HIV testing among young black men who have sex with men. AIDS Behav. 2014;18(5):913–20.PubMedPubMedCentralCrossRef

17.

Bird JDP, Voisin DR. “You’re an open target to be abused”: a qualitative study of stigma and HIV self-disclosure among Black men who have sex with men. AJPH. 2013;103(12):2193–9.CrossRef

18.

Carey JW, Carnes N, Schoua-Glusberg A, Kenward K, Gelaude D, Denson D, et al. Barriers and facilitators for clinical care engagement among HIV-positive African American and Latino men who have sex with men. AIDS Patient Care STDs. 2018;32(5):191–201.PubMedCrossRef

19.

Goodreau SM, Rosenberg ES, Jenness SM, Luisi N, Stansfield SE, Millett GA, et al. Sources of racial disparities in HIV prevalence in men who have sex with men in Atlanta, GA, USA: a modelling study. Lancet HIV. 2017;4(7):e311–20.PubMedPubMedCentralCrossRef

20.

Rosenberg ES, Millett GA, Sullivan PS, Del Rio C, Curran JW. Understanding the HIV disparities between black and white men who have sex with men in the USA using the HIV care continuum: a modeling study. Lancet HIV. 2014;1(3):e112–8.PubMedPubMedCentralCrossRef

21.

Kelley CF, Kahle E, Siegler A, Sanchez T, Del Rio C, Sullivan PS, et al. Applying a PrEP continuum of care for men who have sex with men in Atlanta, Georgia. Clin Infect Dis. 2015;61(10):1590–7.PubMedPubMedCentralCrossRef

22.

Nunn AS, Brinkley-Rubinstein L, Oldenburg CE, Mayer KH, Mimiaga M, Patel R, et al. Defining the HIV pre-exposure prophylaxis care continuum. AIDS. 2017;31(5):731–4.PubMedCrossRef

23.

Peters MDJ, Godfrey CM, Khalil H, McInerney P, Parker D, Soares CB. Guidance for conducting systematic scoping reviews. Int. J. Evid-Based Healthcare. 2015;13(3):141–6.CrossRef

24.

Crosby RA, Geter A, DiClemente RJ, Salazar LF. Acceptability of condoms, circumcision and PrEP among young Black men who have sex with men: a descriptive study based on effectiveness and cost. Vaccines. 2014;2(1):129–37.PubMedPubMedCentralCrossRef

25.

Garcia J, Parker C, Parker RG, Wilson PA, Philbin M, Hirsch JS. Psychosocial implications of homophobia and HIV stigma in social support networks: insights for high-impact HIV prevention among Black men who have sex with men. Health Educ Behav. 2016;43(2):217–25.PubMedCrossRef

26.

Philbin MM, Parker CM, Parker RG, Wilson PA, Garcia J, Hirsch JS. The promise of pre-exposure prophylaxis for Black men who have sex with men: an ecological approach to attitudes, beliefs, and barriers. AIDS Patient Care STDs. 2016;30(6):282–90.PubMedPubMedCentralCrossRef

27.

Behler RL, Cornwell BT, Schneider JA. Patterns of social affiliations and healthcare engagement among young, Black, men who have sex with men. AIDS Behav. 2018;22(3):806–18.PubMedPubMedCentralCrossRef

28.

Rolle C-P, Rosenberg ES, Siegler AJ, Sanchez TH, Luisi N, Weiss K, et al. Challenges in translating PrEP interest into uptake in an observational study of young Black MSM. J Acquir Immune Defic Syndr. 2017;76(3):250–8.PubMedPubMedCentralCrossRef

29.

Smith DK, Toledo L, Smith DJ, Adams MA, Rothenberg R. Attitudes and program preferences of African-American urban young adults about pre-exposure prophylaxis (PrEP). AIDS Educ Prev. 2012;24(5):408–21.PubMedCrossRef

30.

Brooks RA, Allen VC Jr, Regan R, Mutchler MG, Cervantes-Tadeo R, Lee S-J. HIV/AIDS conspiracy beliefs and intention to adopt preexposure prophylaxis among black men who have sex with men in Los Angeles. Int J STD AIDS. 2018;29(4):375–81.PubMedCrossRef

31.

Arrington-Sanders R, Morgan A, Oidtman J, Qian I, Celentano D, Beyrer C. A medical care missed opportunity: preexposure prophylaxis and young Black men who have sex with men. J Adolesc Health. 2016;59(6):725–8.PubMedCrossRef

32.

Desrosiers A, Levy M, Dright A, Zumer M, Jallah N, Kuo I, et al. A randomized controlled pilot study of a culturally-tailored counseling intervention to increase uptake of HIV pre-exposure prophylaxis among young Black men who have sex with men in Washington, DC. AIDS Behav. 2019;23(1):105–15.PubMedCrossRefPubMedCentral

33.

Serota DP, Rosenberg ES, Lockard AM, Rolle CM, Luisi N, Cutro S, et al. Beyond the biomedical: preexposure prophylaxis failures in a cohort of young Black men who have sex with men in Atlanta, Georgia. Clin Infect Dis. 2018;67(6):965–70.PubMedPubMedCentralCrossRef

34.

Cahill S, Taylor SW, Elsesser SA, Mena L, Hickson D, Mayer KH. Stigma, medical mistrust, and perceived racism may affect PrEP awareness and uptake in Black compared to White gay and bisexual men in Jackson, Mississippi and Boston, Massachusetts. AIDS Care. 2017;29(11):1351–8.PubMedPubMedCentralCrossRef

35.

Fallon SA, Park JN, Ogbue CP, Flynn C, German D. Awareness and acceptability of pre-exposure HIV prophylaxis among men who have sex with men in Baltimore. AIDS Behav. 2017;21(5):1268–77.PubMedCrossRef

36.

Kubicek K, Arauz-Cuadra C, Kipke MD. Attitudes and perceptions of biomedical HIV prevention methods: voices from young men who have sex with men. Arch Sex Behav. 2015;44(2):487–97.PubMedPubMedCentralCrossRef

37.

Mimiaga MJ, Closson EF, Battle S, Herbst JH, Denson D, Pitts N, et al. Reactions and receptivity to framing HIV prevention message concepts about pre-exposure prophylaxis for Black and Latino men who have sex with men in three urban US cities. AIDS Patient Care STDs. 2016;30(10):484–9.PubMedCrossRef

38.

Mutchler MG, McDavitt B, Ghani MA, Nogg K, Winder TJA, Soto JK. Getting PrEPared for HIV prevention navigation: young Black gay men talk about HIV prevention in the biomedical era. AIDS Patient Care STDs. 2015;29(9):490–502.PubMedPubMedCentralCrossRef

39.

Daughtridge GW, Conyngham SC, Ramirez N, Koenig HC. I am men’s health: generating adherence to HIV pre-exposure prophylaxis (PrEP) in young men of color who have sex with men. J Int Assoc Provid AIDS Care (JIAPAC). 2015;14(2):103–7.PubMedCrossRef

40.

Havens PL, Stephensen CB, Van Loan MD, Schuster GU, Woodhouse LR, Flynn PM, et al. Decline in bone mass with tenofovir disoproxil fumarate/emtricitabine is associated with hormonal changes in the absence of renal impairment when used by HIV-uninfected adolescent boys and young men for HIV preexposure prophylaxis. Clin Infect Dis. 2017;64(3):317–25.PubMedCrossRef

41.

Thomann M, Grosso A, Zapata R, Chiasson MA. ‘WTF is PrEP?’: attitudes towards pre-exposure prophylaxis among men who have sex with men and transgender women in New York City. Cult Health Sex. 2018;20(7):772–86.PubMedCrossRef

42.

Garnett M, Hirsch-Moverman Y, Franks J, Hayes-Larson E, El-Sadr WM, Mannheimer S. Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York city. AIDS Care. 2018;30(1):9–17.PubMedCrossRef

43.

Biello KB, Hosek S, Drucker MT, Belzer M, Mimiaga MJ, Marrow E, et al. Preferences for injectable PrEP among young U. S. cisgender men and transgender women and men who have sex with men. Arch Sex Behav. 2018;47(7):2101–7.PubMedCrossRef

44.

Downing M, Antebi-Gruszka N, Schrimshaw E, Hirshfield S. If you film it will they watch? Factors associated with willingness to view safer sex messaging in internet-based sexually explicit media. AIDS Behav. 2018;22(4):1295–312.PubMedCrossRef

45.

Arrington-Sanders R, Wilson CM, Perumean-Chaney SE, Patki A, Hosek S. The role of sociobehavioral factors in subprotective TFV-DP levels among YMSM enrolled in 2 PrEP trials. J Acquir Immune Defic Syndr. 2018;80(2):160–5.CrossRef

46.

Havens PL, Tamhane A, Stephensen CB, Schuster GU, Gordon CM, Liu N, et al. Association of vitamin D insufficiency and protective tenofovir diphosphate concentrations with bone toxicity in adolescent boys and young men using tenofovir disoproxil fumarate/emtricitabine for HIV Pre-exposure prophylaxis. AIDS Res Hum Retrovir. 2018;35(2):123–8.PubMedCrossRef

47.

Brooks RA, Landovitz RJ, Kaplan RL, Lieber E, Lee SJ, Barkley TW. Sexual risk behaviors and acceptability of HIV pre-exposure prophylaxis among HIV-negative gay and bisexual men in serodiscordant relationships: a mixed methods study. AIDS Patient Care STDs. 2012;26(2):87–94.PubMedPubMedCentralCrossRef

48.

Golub SA, Gamarel KE, Surace A. Demographic differences in PrEP-related stereotypes: implications for implementation. AIDS Behav. 2017;21(5):1229–35.PubMedPubMedCentralCrossRef

49.

Kuhns LM, Hotton AL, Schneider J, Garofalo R, Fujimoto K. Use of pre-exposure prophylaxis (PrEP) in young men who have sex with men is associated with race, sexual risk behavior and peer network size. AIDS Behav. 2017;21(5):1376–82.PubMedPubMedCentralCrossRef

50.

Mustanski B, Johnson AK, Garofalo R, Ryan D, Birkett M. Perceived likelihood of using HIV pre-exposure prophylaxis medications among young men who have sex with men. AIDS Behav. 2013;17(6):2173–9.PubMedPubMedCentralCrossRef

51.

Pines HA, Gorbach PM, Weiss RE, Shoptaw S, Landovitz RJ, Javanbakht M, et al. Sexual risk trajectories among MSM in the United States: implications for pre-exposure prophylaxis delivery. J Acquir Immune Defic Syndr. 2014;65(5):579–86.PubMedPubMedCentralCrossRef

52.

Taylor SW, Mayer KH, Elsesser SM, Mimiaga MJ, O’Cleirigh C, Safren SA. Optimizing content for pre-exposure prophylaxis (PrEP) counseling for men who have sex with men: perspectives of PrEP users and high-risk PrEP naive men. AIDS Behav. 2014;18(5):871–9.PubMedCentralCrossRef

53.

Koester KA, Liu A, Eden C, Amico KR, McMahan V, Goicochea P, et al. Acceptability of drug detection monitoring among participants in an open-label pre-exposure prophylaxis study. AIDS Care. 2015;27(10):1199–204.PubMedPubMedCentralCrossRef

54.

Rolle C-P, Rosenberg ES, Luisi N, Grey J, Sanchez T, Del Rio C, et al. Willingness to use pre-exposure prophylaxis among Black and White men who have sex with men in Atlanta, Georgia. Int J STD AIDS. 2017;28(9):849–57.PubMedCrossRef

55.

Smith DK, Herbst JH, Rose CE. Estimating HIV protective effects of method adherence with combinations of preexposure prophylaxis and condom use among African American men who have sex with men. Sex Transm Dis. 2015;42(2):88–92.PubMedCrossRef

56.

Hamilton DT, Goodreau SM, Jenness SM, Sullivan PS, Wang LY, Dunville RL, et al. Potential impact of HIV preexposure prophylaxis among Black and White adolescent sexual minority males. AJPH. 2018;108(S4):S284–91.CrossRef

57.

Smith DK, Van Handel M, Grey J. Estimates of adults with indications for HIV pre-exposure prophylaxis by jurisdiction, transmission risk group, and race/ethnicity, United States, 2015. Ann Epidemiol. 2018;28(12):850–7.PubMedCrossRef

58.

Jenness SM, Maloney KM, Smith DK, Karen W, Goodreau SM, Rosenberg ES, et al. Addressing gaps in HIV preexposure prophylaxis care to reduce racial disparities in HIV incidence in the United States. Am J Epidemiol. 2018;188(4):743–52.CrossRefPubMedCentral

59.

Fauci AS, Redfield RR, Sigounas G, Weahkee MD, Giroir BP. Ending the HIV epidemic: a plan for the United States. JAMA. 2019;321(9):844–5.PubMedCrossRef

Titel: The PrEP Care Continuum and Black Men Who Have Sex with Men: A Scoping Review of Published Data on Awareness, Uptake, Adherence, and Retention in PrEP Care
verfasst von: Ogochukwu Ezennia
Angelica Geter
Dawn K. Smith
Publikationsdatum: 28.08.2019
Verlag: Springer US
Erschienen in: AIDS and Behavior / Ausgabe 10/2019
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-019-02641-2

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