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AIDS and Behavior
Erschienen in: AIDS and Behavior 2/2017

09.09.2016 | Substantive Review

The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis

verfasst von: Haochu Li, Gifty Marley, Wei Ma, Chongyi Wei, Mellanye Lackey, Qingyan Ma, Françoise Renaud, Marco Vitoria, Rachel Beanland, Meg Doherty, Joseph D. Tucker

Erschienen in: AIDS and Behavior | Ausgabe 2/2017

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Abstract

Poor adherence remains a major barrier to achieving the clinical and public health benefits of antiretroviral drugs (ARVs). A systematic review and qualitative meta-synthesis was conduct to evaluate how ARV adverse drug reactions may influence ARV adherence. Thirty-nine articles were identified, and 33 reported that ARV adverse drug reactions decreased adherence and six studies found no influence. Visually noticeable adverse drug reactions and psychological adverse reactions were reported as more likely to cause non-adherence compared to other adverse drug reactions. Six studies reported a range of adverse reactions associated with EFV-containing regimens contributing to decreased adherence. Informing HIV-infected individuals about ARV adverse drug reactions prior to initiation, counselling about coping mechanisms, and experiencing the effectiveness of ARVs on wellbeing may improve ARV adherence.
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Metadaten
Titel
The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis
verfasst von
Haochu Li
Gifty Marley
Wei Ma
Chongyi Wei
Mellanye Lackey
Qingyan Ma
Françoise Renaud
Marco Vitoria
Rachel Beanland
Meg Doherty
Joseph D. Tucker
Publikationsdatum
09.09.2016
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 2/2017
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-016-1545-0

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