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Erschienen in: International Ophthalmology 4/2018

12.06.2017 | Original Paper

The significance of neutrophil-to-lymphocyte ratio in idiopathic epiretinal membrane

verfasst von: Funda Dikkaya, Sevil Karaman Erdur, Mustafa Ozsutcu, Rukiye Aydin, Mehmet Selim Kocabora, Cengiz Aras

Erschienen in: International Ophthalmology | Ausgabe 4/2018

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Abstract

Purpose

To assess the levels of neutrophil-to-lymphocyte ratio (NLR) in patients with idiopathic epiretinal membrane (iERM) and to compare the NLR results of patients with iERM and healthy controls.

Methods

This retrospective study enrolled 43 patients with iERM and 40 healthy subjects. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection.

Results

There was a significant difference in NLR between iERM and control groups (p < 0.01). The receiver operating characteristics analysis revealed that the value of NLR to distinguish patients with iERM and controls was found to be 0.832. The best cutoff value was 1.90, with a sensitivity of 72% and specificity 70%.

Conclusions

Our study for the first time provides evidence that subclinical systemic inflammation may cause or at least accompanies iERM using a novel biomarker NLR.
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Metadaten
Titel
The significance of neutrophil-to-lymphocyte ratio in idiopathic epiretinal membrane
verfasst von
Funda Dikkaya
Sevil Karaman Erdur
Mustafa Ozsutcu
Rukiye Aydin
Mehmet Selim Kocabora
Cengiz Aras
Publikationsdatum
12.06.2017
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 4/2018
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-017-0597-0

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