Skip to main content
Erschienen in:

01.06.2011 | Review Article

The surgical anatomy and etiology of gastrointestinal fistulas

verfasst von: J. Pfeifer, G. Tomasch, S. Uranues

Erschienen in: European Journal of Trauma and Emergency Surgery | Ausgabe 3/2011

Einloggen, um Zugang zu erhalten

Abstract

Background

Fistulas are abnormal communications between two epithelial surfaces, either between two portions of the intestine, between the intestine and some other hollow viscus, or between the intestine and the skin of the abdominal wall. The etiology of intestinal fistulas is in most cases a result of multiple contributing factors. Despite significant advances in their management over the past decades, intestinal fistulas remain a major clinical problem, with a high overall mortality rate of up to 30% due to the high rate of complications. This paper aims to describe classification systems based on the anatomy, physiology and etiology that may be helpful in the clinical management of intestinal fistulas.

Methods

On the basis of anatomical differences, fistulas can be classified based by the site of origin, by site of their openings, or as simple or complex. Physiologic classification as low, moderate or high output fistulas is most useful for the non-surgical approach. Concerning the etiology, we classified the possible causes as (postoperative) trauma, inflammation, infection, malignancy, radiation injury or congenital.

Conclusion

Fistula formation can cause a number of serious or debilitating complications ranging from disturbance of fluid and electrolyte balance to sepsis and even death. They still remain an important complication following gastrointestinal surgery.
Literatur
1.
Zurück zum Zitat Evenson AR, Fischer JE. Current management of enterocutaneous fistula. J Gastrointest Surg. 2006;10(3):455–64.PubMedCrossRef Evenson AR, Fischer JE. Current management of enterocutaneous fistula. J Gastrointest Surg. 2006;10(3):455–64.PubMedCrossRef
2.
Zurück zum Zitat Hollington P, Mawdsley J, Lim W, Gabe SM, Forbes A, Windsor AJ. An 11 year experience of enterocutaneous fistula. Br J Surg. 2004;91(12):1646–51.PubMedCrossRef Hollington P, Mawdsley J, Lim W, Gabe SM, Forbes A, Windsor AJ. An 11 year experience of enterocutaneous fistula. Br J Surg. 2004;91(12):1646–51.PubMedCrossRef
3.
Zurück zum Zitat Singh B, Haffejee AA, Allopi L, Moodley J. Surgery for high-output small bowel enterocutaneous fistula: a 30 year experience. Int Surg. 2009;94(3):262–8.PubMed Singh B, Haffejee AA, Allopi L, Moodley J. Surgery for high-output small bowel enterocutaneous fistula: a 30 year experience. Int Surg. 2009;94(3):262–8.PubMed
4.
Zurück zum Zitat Visschers RG, Olde Damink SW, Winkens B, Soeters PB, van Gemert WG. Treatment strategies in 135 consecutive patients with enterocutaneous fistulas. World J Surg. 2008;32(3):445–53.PubMedCrossRef Visschers RG, Olde Damink SW, Winkens B, Soeters PB, van Gemert WG. Treatment strategies in 135 consecutive patients with enterocutaneous fistulas. World J Surg. 2008;32(3):445–53.PubMedCrossRef
5.
Zurück zum Zitat Tassiopoulos AK, Baum G, Halverson JD. Small bowel fistulas. Surg Clin North Am. 1996;76(5):1175–81.PubMedCrossRef Tassiopoulos AK, Baum G, Halverson JD. Small bowel fistulas. Surg Clin North Am. 1996;76(5):1175–81.PubMedCrossRef
6.
Zurück zum Zitat Berry SM, Fischer JE. Classification and pathophysiology of enterocutaneous fistulas. Surg Clin North Am. 1996;76(5):1009–18.PubMedCrossRef Berry SM, Fischer JE. Classification and pathophysiology of enterocutaneous fistulas. Surg Clin North Am. 1996;76(5):1009–18.PubMedCrossRef
7.
Zurück zum Zitat Wong WD, Buie WD. Management of intestinal fistulas. In: MacKeigan JM, Cataldo PA, editors. Intestinal stomas. Missouri: Quality Medical Publishing; 1993. p. 278–306. Wong WD, Buie WD. Management of intestinal fistulas. In: MacKeigan JM, Cataldo PA, editors. Intestinal stomas. Missouri: Quality Medical Publishing; 1993. p. 278–306.
8.
Zurück zum Zitat Sivchev S, Koiunderliev P, Gruev G. Coincidence of partially patent urachus and omphaloenteric canal originating from the colon. Khirurgiia. 1970;23(4):398–400.PubMed Sivchev S, Koiunderliev P, Gruev G. Coincidence of partially patent urachus and omphaloenteric canal originating from the colon. Khirurgiia. 1970;23(4):398–400.PubMed
9.
Zurück zum Zitat Han HJ, Kim CY, Choi SB, Kwak JM, Lee SI. Sigmoid colon fistula following totally extraperitoneal hernioplasty: an improper treatment for mesh infection or iatrogenic injury? Hernia. 2010;14(6):655–8.PubMedCrossRef Han HJ, Kim CY, Choi SB, Kwak JM, Lee SI. Sigmoid colon fistula following totally extraperitoneal hernioplasty: an improper treatment for mesh infection or iatrogenic injury? Hernia. 2010;14(6):655–8.PubMedCrossRef
10.
Zurück zum Zitat Boutros C, Somasundar P, Espat NJ. Early results on the use of biomaterials as adjuvant to abdominal wall closure following cytoreduction and hyperthermic intraperitoneal chemotherapy. World J Surg Oncol. 2010;20(8):72.CrossRef Boutros C, Somasundar P, Espat NJ. Early results on the use of biomaterials as adjuvant to abdominal wall closure following cytoreduction and hyperthermic intraperitoneal chemotherapy. World J Surg Oncol. 2010;20(8):72.CrossRef
11.
Zurück zum Zitat Szitkar B, Yzet T, Auquier M, Robert B, Lafaye-Boucher N, Verhaeghe P, Remond A. Late complications from abdominal wall surgery: report of three cases of mesh migration into hollow viscus. J Radiol. 2010; 91(1 Pt 1):59–64. Szitkar B, Yzet T, Auquier M, Robert B, Lafaye-Boucher N, Verhaeghe P, Remond A. Late complications from abdominal wall surgery: report of three cases of mesh migration into hollow viscus. J Radiol. 2010; 91(1 Pt 1):59–64.
12.
Zurück zum Zitat Tam KW, Wei PL, Kuo LJ, Wu CH. Systematic review of the use of a mesh to prevent parastomal hernia. World J Surg. 2010;34(11):2723–9.PubMedCrossRef Tam KW, Wei PL, Kuo LJ, Wu CH. Systematic review of the use of a mesh to prevent parastomal hernia. World J Surg. 2010;34(11):2723–9.PubMedCrossRef
13.
Zurück zum Zitat Merad F, Hay JM, Fingerhut A, Yahchouchi E, Laborde Y, Pélissier E, Msika S, Flamant Y. Is prophylactic pelvic drainage useful after elective rectal or anal anastomosis? A multicenter controlled randomized trial. French Association for Surgical Research. Surgery. 1999;125(5):529–35.PubMedCrossRef Merad F, Hay JM, Fingerhut A, Yahchouchi E, Laborde Y, Pélissier E, Msika S, Flamant Y. Is prophylactic pelvic drainage useful after elective rectal or anal anastomosis? A multicenter controlled randomized trial. French Association for Surgical Research. Surgery. 1999;125(5):529–35.PubMedCrossRef
14.
Zurück zum Zitat Karliczek A, Jesus EC, Matos D, Castro AA, Atallah AN, Wiggers T. Drainage or nondrainage in elective colorectal anastomosis: a systematic review and meta-analysis. Colorectal Dis. 2006;8(4):259–65.PubMedCrossRef Karliczek A, Jesus EC, Matos D, Castro AA, Atallah AN, Wiggers T. Drainage or nondrainage in elective colorectal anastomosis: a systematic review and meta-analysis. Colorectal Dis. 2006;8(4):259–65.PubMedCrossRef
15.
Zurück zum Zitat Jesus EC, Karliczek A, Matos D, Castro AA, Atallah AN. Prophylactic anastomotic drainage for colorectal surgery. Cochrane Database Syst Rev. 2004; 18(4):CD002100. Jesus EC, Karliczek A, Matos D, Castro AA, Atallah AN. Prophylactic anastomotic drainage for colorectal surgery. Cochrane Database Syst Rev. 2004; 18(4):CD002100.
16.
Zurück zum Zitat Yilmaz M, Isik B, Sogutlu G, Ara C, Yilmaz S, Kirimlioğlu V. Duodeno-sigmoid fistula due to ingested metallic wire. J Emerg Med. 2008;34(1):83–4.PubMedCrossRef Yilmaz M, Isik B, Sogutlu G, Ara C, Yilmaz S, Kirimlioğlu V. Duodeno-sigmoid fistula due to ingested metallic wire. J Emerg Med. 2008;34(1):83–4.PubMedCrossRef
17.
Zurück zum Zitat Read TE, Jacono F, Prakash C. Coloenteric fistula from chicken-bone perforation of the sigmoid colon. Surgery. 1999;125(3):354–6.PubMedCrossRef Read TE, Jacono F, Prakash C. Coloenteric fistula from chicken-bone perforation of the sigmoid colon. Surgery. 1999;125(3):354–6.PubMedCrossRef
18.
Zurück zum Zitat Aliev SA. Injury of large intestine in urgent surgery. Khirurgiia Mosk. 2000;10:35–40.PubMed Aliev SA. Injury of large intestine in urgent surgery. Khirurgiia Mosk. 2000;10:35–40.PubMed
19.
Zurück zum Zitat Eid HO, Hefny AF, Joshi S, Abu-Zidan FM. Non-traumatic perforation of the small bowel. Afr Health Sci. 2008;8(1):36–9.PubMed Eid HO, Hefny AF, Joshi S, Abu-Zidan FM. Non-traumatic perforation of the small bowel. Afr Health Sci. 2008;8(1):36–9.PubMed
20.
Zurück zum Zitat Jain BK, Arora H, Srivastava UK, Mohanty D, Garg PK. Insight into the management of non-traumatic perforation of the small intestine. J Infect Dev Ctries. 2010;4(10):650–4.PubMed Jain BK, Arora H, Srivastava UK, Mohanty D, Garg PK. Insight into the management of non-traumatic perforation of the small intestine. J Infect Dev Ctries. 2010;4(10):650–4.PubMed
21.
Zurück zum Zitat Agrawal V, Prasad S. Appendico-cutaneous fistula: a diagnostic dilemma. Trop Gastroenterol. 2003;24(2):87–9.PubMed Agrawal V, Prasad S. Appendico-cutaneous fistula: a diagnostic dilemma. Trop Gastroenterol. 2003;24(2):87–9.PubMed
22.
Zurück zum Zitat Deorah S, Seenu V, Pradeep KK, Sharma S. Spontaneous appendico-cutaneous fistula—a rare complication of acute appendicitis. Trop Gastroenterol. 2005;26(1):48–50.PubMed Deorah S, Seenu V, Pradeep KK, Sharma S. Spontaneous appendico-cutaneous fistula—a rare complication of acute appendicitis. Trop Gastroenterol. 2005;26(1):48–50.PubMed
23.
Zurück zum Zitat Prieto-Nieto I, Perez-Robledo JP, Hardisson D, Rodriguez-Montes JA, Larrauri-Martinez J, Garcia-Sancho-Martin L. Crohn’s disease limited to the appendix. Am J Surg. 2001;182(5):531–3.PubMedCrossRef Prieto-Nieto I, Perez-Robledo JP, Hardisson D, Rodriguez-Montes JA, Larrauri-Martinez J, Garcia-Sancho-Martin L. Crohn’s disease limited to the appendix. Am J Surg. 2001;182(5):531–3.PubMedCrossRef
24.
Zurück zum Zitat Pătraşcu T, Catrina E, Doran H, Mihalache O, Bugă C, Degeratu D, Predescu G. Surgical management of small bowel localization of Crohn’s disease. Chirurgia (Bucur). 2009;104(6):705–14. Pătraşcu T, Catrina E, Doran H, Mihalache O, Bugă C, Degeratu D, Predescu G. Surgical management of small bowel localization of Crohn’s disease. Chirurgia (Bucur). 2009;104(6):705–14.
25.
Zurück zum Zitat Delaney CP, Fazio VW. Crohn’s disease of the small bowel. Surg Clin North Am. 2001;81:137–58.PubMedCrossRef Delaney CP, Fazio VW. Crohn’s disease of the small bowel. Surg Clin North Am. 2001;81:137–58.PubMedCrossRef
26.
Zurück zum Zitat Rubesin SE, Scotiniotis I, Birnbaum BA, Ginsberg GG. Radiologic and endoscopic diagnosis of Crohn’s disease. Surg Clin North Am. 2001;81:39–70.PubMedCrossRef Rubesin SE, Scotiniotis I, Birnbaum BA, Ginsberg GG. Radiologic and endoscopic diagnosis of Crohn’s disease. Surg Clin North Am. 2001;81:39–70.PubMedCrossRef
27.
Zurück zum Zitat Zimmerer T, Böcker U, Wenz F, Singer MV. Medical prevention and treatment of acute and chronic radiation induced enteritis - is there any proven therapy? A short review. Z Gastroenterol. 2008;46(5):441–8.PubMedCrossRef Zimmerer T, Böcker U, Wenz F, Singer MV. Medical prevention and treatment of acute and chronic radiation induced enteritis - is there any proven therapy? A short review. Z Gastroenterol. 2008;46(5):441–8.PubMedCrossRef
28.
Zurück zum Zitat Kwon SH, Oh JH, Kim HJ, Park SJ, Park HC. Interventional management of gastrointestinal fistulas. Korean J Radiol. 2008;9(6):541–9.PubMedCrossRef Kwon SH, Oh JH, Kim HJ, Park SJ, Park HC. Interventional management of gastrointestinal fistulas. Korean J Radiol. 2008;9(6):541–9.PubMedCrossRef
29.
Zurück zum Zitat Ercoli FR, Milgrim LM, Nosher JL, et al. Percutaneous catheter drainage of abscesses associated with enteric fistulae. Am Surg. 1988;54:45–9.PubMed Ercoli FR, Milgrim LM, Nosher JL, et al. Percutaneous catheter drainage of abscesses associated with enteric fistulae. Am Surg. 1988;54:45–9.PubMed
30.
Zurück zum Zitat Papanicolaou N, Mueller PR, Ferrucci JT. Abscess–fistula association: radiologic recognition and percutaneous management. AJR. 1984;143:811–5.PubMed Papanicolaou N, Mueller PR, Ferrucci JT. Abscess–fistula association: radiologic recognition and percutaneous management. AJR. 1984;143:811–5.PubMed
31.
Zurück zum Zitat Kerlan RJ, Jeffrey RB, Pogany AC, et al. Abdominal abscess with low-output fistula: successful percutaneous drainage. Radiology. 1985;155:73–5.PubMed Kerlan RJ, Jeffrey RB, Pogany AC, et al. Abdominal abscess with low-output fistula: successful percutaneous drainage. Radiology. 1985;155:73–5.PubMed
32.
Zurück zum Zitat Falconi M, Pederzoli P. The relevance of gastrointestinal fistulae in clinical practice: a review. Gut. 2001;49(Suppl 4):iv2–10.PubMedCrossRef Falconi M, Pederzoli P. The relevance of gastrointestinal fistulae in clinical practice: a review. Gut. 2001;49(Suppl 4):iv2–10.PubMedCrossRef
Metadaten
Titel
The surgical anatomy and etiology of gastrointestinal fistulas
verfasst von
J. Pfeifer
G. Tomasch
S. Uranues
Publikationsdatum
01.06.2011
Verlag
Springer-Verlag
Erschienen in
European Journal of Trauma and Emergency Surgery / Ausgabe 3/2011
Print ISSN: 1863-9933
Elektronische ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-011-0104-7

Weitere Artikel der Ausgabe 3/2011

European Journal of Trauma and Emergency Surgery 3/2011 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie erweitert durch Fallbeispiele, Videos und Abbildungen. Zur Fortbildung und Wissenserweiterung, verfasst und geprüft von Expertinnen und Experten der Gesellschaft für Arthroskopie und Gelenkchirurgie (AGA).


Jetzt entdecken!

Neu im Fachgebiet Orthopädie und Unfallchirurgie

Morton-Neurom – besser Kortikoid oder Hyaluronsäure spritzen?

Dieser Vergleich hat einen klaren Ausgang: Forschende aus São Paulo haben die Wirkung ultraschallgesteuerter Kortikoidinjektionen gegen die Beschwerden des Morton-Neuroms mit den Effekten von Hyaluronsäureinjektionen verglichen. Das Fazit für die Praxis ist deutlich.

Morbus Dupuytren: Kollagenase-Injektion versus partielle Aponeurektomie

In der Behandlung von mittelschweren Dupuytren-Kontrakturen können Kollagenase-Injektionen von der Wirksamkeit her nicht mit der limitierten Aponeurektomie mithalten. Das hat der direkte Vergleich der beiden Methoden in der DISC-Studie ergeben.

Neue Osteoporose-Leitlinie: Frakturinzidenz senken, Versorgung verbessern

Das sind – zusammen mit dem Erhalt bzw. der Verbesserung der Funktionsfähigkeit und Lebensqualität der Patientinnen und Patienten – die Ziele der 2023er Leitlinie der Osteologischen Fachgesellschaften e.V. (DVO). Noch fremdeln viele Ärztinnen und Ärzte mit den neuen Konzepten und Risikotabellen. 

Myositiden – Fortschritte bei der Risikostratifizierung und Diagnostik

Bei der Myositis hat sich viel getan, was für den klinischen Alltag relevant ist – so Prof. Dr. Britta Maurer, Universitätsspital Bern, beim Deutschen Rheumatologiekongress 2024. Morbidität und Mortalität könnten zurückgehen.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.