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Erschienen in: Heart Failure Reviews 5/2022

07.11.2021

The utility of positron emission tomography in cardiac amyloidosis

verfasst von: Subha Saeed, Jean Michel Saad, Ahmed Ibrahim Ahmed, Yushui Han, Mouaz H. Al-Mallah

Erschienen in: Heart Failure Reviews | Ausgabe 5/2022

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Abstract

Cardiac amyloidosis, characterized by progressive restrictive cardiomyopathy, presents unusual diagnostic challenges. Conventional cardiac scintigraphy has shown limited utility in the quantification of disease burden and serial follow-up of cardiac amyloidosis. The advent of specialized positron emission tomography with specific amyloid-binding radiotracers has the potential to change currently employed diagnostic algorithms for the imaging of cardiac amyloidosis. This review aims to discuss the diagnostic utility of amyloid-binding radiotracers, including Pittsburg compound B, florbetapir, florbetapan, and sodium fluoride. These tracers have promising potential for the early detection of the particular type of cardiac amyloidosis, pursuing relevant medical intervention, assessing amyloid burden, monitoring treatment response, and overall prognostication.
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Metadaten
Titel
The utility of positron emission tomography in cardiac amyloidosis
verfasst von
Subha Saeed
Jean Michel Saad
Ahmed Ibrahim Ahmed
Yushui Han
Mouaz H. Al-Mallah
Publikationsdatum
07.11.2021
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 5/2022
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-021-10183-w

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