Erschienen in:
01.02.2013 | Original Article
Tolerance to Ischemia—an Increasingly Complex Biology
verfasst von:
Robert Meller, Roger P. Simon
Erschienen in:
Translational Stroke Research
|
Ausgabe 1/2013
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Abstract
In this review, we identify and discuss some of the genomics studies of preconditioning and the ischemic tolerance phenomenon. Such studies have been attempted in multiple species, using different array technologies and with different preconditioning and tolerance models. In addition, studies are starting to reveal epigenetic mechanisms and modifiers of tolerance and preconditioning. Together these studies are starting to reveal some of the immense complexity of the ischemic tolerance phenomenon, yet further studies await to be performed.