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Journal of the Association for Research in Otolaryngology

Erschienen in:

01.02.2014 | Research Article

Tonotopic Morphometry of the Lamina Reticularis of the Guinea Pig Cochlea with Associated Microstructures and Related Mechanical Implications

verfasst von: Yury M. Yarin, Andrei N. Lukashkin, Anton A. Poznyakovskiy, Heike Meißner, Mario Fleischer, Johannes Baumgart, Claudia Richter, Eberhard Kuhlisch, Thomas Zahnert

Erschienen in: Journal of the Association for Research in Otolaryngology | Ausgabe 1/2014

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Abstract

Morphometry of the lamina reticularis of the guinea pig cochlea was performed using scanning electron microscopy. Seventy-four geometrical parameters of the lamina reticularis, the bundles of stereocilia, and individual stereocilia, in all rows of hair cells and within the individual hair cells, were measured at ten equally spaced locations along the longitudinal direction of the cochlea. Variations of the parameters versus the longitudinal coordinate were statistically analyzed and fitted with polynomials (constant, linear, or quadratic). Our data show that a unique set of geometrical parameters of inner and outer hair cells is typical for every frequency-dependent position at the lamina reticularis. Morphology of the outer hair cell structures varies more than respective parameters of the inner hair cells. Mechanical modeling using the obtained geometrical parameters provides a novel glance at the mechanical characteristics with respect to the cochlear tonotopy.

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Titel: Tonotopic Morphometry of the Lamina Reticularis of the Guinea Pig Cochlea with Associated Microstructures and Related Mechanical Implications
verfasst von: Yury M. Yarin
Andrei N. Lukashkin
Anton A. Poznyakovskiy
Heike Meißner
Mario Fleischer
Johannes Baumgart
Claudia Richter
Eberhard Kuhlisch
Thomas Zahnert
Publikationsdatum: 01.02.2014
Verlag: Springer US
Erschienen in: Journal of the Association for Research in Otolaryngology / Ausgabe 1/2014
Print ISSN: 1525-3961
Elektronische ISSN: 1438-7573
DOI: https://doi.org/10.1007/s10162-013-0420-1

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Tonotopic Morphometry of the Lamina Reticularis of the Guinea Pig Cochlea with Associated Microstructures and Related Mechanical Implications

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