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European Spine Journal

Erschienen in:

01.10.2004 | Review

Tranexamic acid for major spinal surgery

verfasst von: David T. Neilipovitz

Erschienen in: European Spine Journal | Sonderheft 1/2004

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Abstract

Patients who undergo major spinal surgery often require multiple blood transfusions. The antifibrinolytics are medications that can reduce blood-transfusion requirements in cardiac surgery and total knee arthroplasty. The present role of synthetic antifibrinolytics, especially tranexamic acid, in reducing peri-operative blood-transfusion requirements in spine surgery is still unclear. The majority of studies exploring the role of these drugs in spine surgery have limited patient enrolment and report mixed results. The goal of the present review is to discuss the pharmacology of tranexamic acid briefly. A brief synopsis of the studies using the synthetic antifibrinolytics for spine surgery is presented. Finally, the potential risks and the benefits of antifibrinolytics are discussed.

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Titel: Tranexamic acid for major spinal surgery
verfasst von: David T. Neilipovitz
Publikationsdatum: 01.10.2004
Verlag: Springer-Verlag
Erschienen in: European Spine Journal / Ausgabe Sonderheft 1/2004
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI: https://doi.org/10.1007/s00586-004-0716-2

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