Erschienen in:
01.11.2009 | Case Report
Tumefactive intracranial presentation of precursor B-cell acute lymphoblastic leukemia
verfasst von:
Craig M. Forester, Chi L. Braunreiter, Hasan Yaish, Gary L. Hedlund, Zeinab Afify
Erschienen in:
Pediatric Radiology
|
Ausgabe 11/2009
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Abstract
In children, leukemia is the most common malignancy, and approximately 75% of leukemias are acute lymphoblastic leukemia (ALL). Central nervous system leukemia is found at diagnosis in fewer than 5% of children with ALL. Leukemic intracranial masses have been described with acute myeloid leukemia, but ALL presenting as a mass lesion is rare. We describe a unique case of an intracranial confirmed precursor B cell (pre-B) ALL mass in a 13-year-old girl that was diagnosed by brain CT, MRI and cerebral angiography, and confirmed by biopsy. This report details pertinent history and distinguishing imaging features of an intracranial ALL tumefaction.