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Current Osteoporosis Reports
Erschienen in: Current Osteoporosis Reports 2/2021

01.02.2021 | Craniofacial Skeleton (TG Chu and S Akintoye, Section Editors)

Understanding Early-Stage Posttraumatic Osteoarthritis for Future Prospects of Diagnosis: from Knee to Temporomandibular Joint

verfasst von: Fazal-Ur-Rehman Bhatti, Anastasios Karydis, Beth S. Lee, Toru Deguchi, Do-Gyoon Kim, Hongsik Cho

Erschienen in: Current Osteoporosis Reports | Ausgabe 2/2021

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Abstract

Purpose of Review

Many mechanical load-bearing joints of the body are prone to posttraumatic osteoarthritis (PTOA), including the knee joint and temporomandibular joint (TMJ). Early detection of PTOA can be beneficial in prevention or alleviating further progression of the disease.

Recent Findings

Various mouse models, similar to those used in development of novel diagnosis strategies for early stages of OA, have been proposed to study early PTOA. While many studies have focused on OA and PTOA in the knee joint, early diagnostic methods for OA and PTOA of the TMJ are still not well established. Previously, we showed that fluorescent near-infrared imaging can diagnose inflammation and cartilage damage in mouse models of knee PTOA. Here we propose that the same approach can be used for early diagnosis of TMJ-PTOA.

Summary

In this review, we present a brief overview of PTOA, application of relevant mouse models, current imaging methods available to examine TMJ-PTOA, and the prospects of near-infrared optical imaging to diagnose early-stage TMJ-OA.
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Metadaten
Titel
Understanding Early-Stage Posttraumatic Osteoarthritis for Future Prospects of Diagnosis: from Knee to Temporomandibular Joint
verfasst von
Fazal-Ur-Rehman Bhatti
Anastasios Karydis
Beth S. Lee
Toru Deguchi
Do-Gyoon Kim
Hongsik Cho
Publikationsdatum
01.02.2021
Verlag
Springer US
Erschienen in
Current Osteoporosis Reports / Ausgabe 2/2021
Print ISSN: 1544-1873
Elektronische ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-021-00661-3

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