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24.09.2021 | Diagnostic Neuroradiology

Usefulness of rapid MR angiography using two-point Dixon for evaluating carotid and aortic plaques

verfasst von: Keisuke Morihara, Tatsu Nakano, Kentaro Mori, Issei Fukui, Motohiro Nomura, Keiichiro Suzuki, Kenichi Hirano, Mitsuyuki Takahashi, Hideyuki Takeuchi, Hiroshi Doi, Yoshihisa Kitamura, Fumiaki Tanaka

Erschienen in: Neuroradiology | Ausgabe 4/2022

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Abstract

Purpose

Recently, various magnetic resonance imaging (MRI) modalities have been developed to easily detect carotid and aortic plaques, but these techniques are time-consuming and vulnerable to motion artifacts. We investigated the utility of a gradient echo MRI technique known as liver acquisition with volume acceleration flexible (LAVA-Flex) to detect carotid and aortic atherosclerotic plaques.

Methods

Ten patients who underwent carotid endarterectomy (CEA) were assessed regarding the correspondence between LAVA-Flex findings and the histopathology of excised carotid plaques. In addition, 47 patients with cryptogenic ischemic stroke underwent LAVA-Flex and transesophageal echocardiography (TEE) for detection of embolic sources in the thoracic aorta. We analyzed the relationship between the thickness of the aortic plaque measured by TEE and the presence of high-intensity lesions on LAVA-Flex.

Results

Nine of 10 patients (90.0%) who underwent CEA showed a high-intensity carotid lesion on LAVA-Flex, which corresponded pathologically to plaques containing large lipid cores and hemorrhage. Twenty-four (51.1%) of 47 cryptogenic stroke patients showed a high-intensity lesion in the thoracic aorta on LAVA-Flex; of these, 21 (87.5%) also demonstrated a large plaque (thickness ≥4 mm) on TEE. Twenty-two (95.7%) of 23 patients without a high-intensity lesion on LAVA-Flex demonstrated no large plaque on TEE. LAVA-Flex had a sensitivity of 95.5% and a specificity of 88.0% in patients with large plaques.

Conclusion

This study showed that LAVA-Flex successfully detected carotid and aortic plaques. This imaging technique may be useful to rapidly diagnose and evaluate carotid and aortic plaques, which are critical risk factors for aortogenic stroke.

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Titel: Usefulness of rapid MR angiography using two-point Dixon for evaluating carotid and aortic plaques
verfasst von: Keisuke Morihara
Tatsu Nakano
Kentaro Mori
Issei Fukui
Motohiro Nomura
Keiichiro Suzuki
Kenichi Hirano
Mitsuyuki Takahashi
Hideyuki Takeuchi
Hiroshi Doi
Yoshihisa Kitamura
Fumiaki Tanaka
Publikationsdatum: 24.09.2021
Verlag: Springer Berlin Heidelberg
Erschienen in: Neuroradiology / Ausgabe 4/2022
Print ISSN: 0028-3940
Elektronische ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-021-02812-w

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