Background
Methods and materials
Patients
Plan ID. | Main location of tumor | PTV (cm3) | GTV (cm3) | Max. diameter of GTV (cm) | Nominal diameter of GTV (cm) | Normal liver (cm3) | Overlapping of PTV and normal liver (cm3) |
---|---|---|---|---|---|---|---|
1 | The right main branch of the portal vein | 204.7 | 20.1 | 4.7 | 3.4 | 1660.6 | 142.0 |
2 | The main trunk and the main branches of the portal vein | 348.0 | 59.2 | 7.2 | 4.8 | 2645.6 | 189.0 |
3 | The main trunk and the main branches of the portal vein | 341.6 | 70.3 | 8.5 | 5.1 | 2658.7 | 302.3 |
4 | Segment 3, 4 | 381.7 | 82.1 | 6.8 | 5.4 | 1783.5 | 207.8 |
5 | Segment 4, 8 | 405.9 | 130.9 | 7.3 | 6.3 | 814.6 | 300.3 |
6 | Segment 1, 4, 6, 7, 8 | 844.8 | 245.8 | 15.1 | 7.8 | 1312.6 | 310.2 |
7 | Segment 7, 8 | 764.2 | 284.2 | 12.4 | 8.2 | 1216.5 | 367.3 |
8 | Segment 3, 4, 5, 7, 8 | 785.6 | 299.3 | 10.3 | 8.3 | 1339.9 | 411.2 |
9 | Segment 3, 4, 5, 7, 8 | 848.9 | 344.5 | 13.8 | 8.7 | 1676.9 | 399.7 |
10 | Segment 6, 7, 8 | 1488.3 | 720.6 | 15.2 | 11.1 | 965.4 | 489.4 |
11 | Segment 1, 5, 6, 7, 8 | 1822.4 | 916.0 | 15.4 | 12.1 | 1088.7 | 563.2 |
12 | Segment 1, 4, 5, 6, 7, 8 | 2222.6 | 1638.9 | 18.0 | 14.6 | 1087.5 | 621.7 |
13 | Segment 1, 4, 5, 6, 7, 8 | 3094.2 | 2194.5 | 22.0 | 16.1 | 629.2 | 630.1 |
Mean | - | 1042.5 | 539.0 | - | 8.6 | 1452.3 | 379.6 |
Treatment planning
Evaluation
DVH normalization
Effective volumes
Statistical analysis
Results
DVH comparison among plans
ID. | Nominal diameter of GTV (cm) | V33 | V42 | Veff* | DMean | Mean FED* | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IMRT (%) | SSPT (%) | IMRT (%) | SSPT (%) | IMRT | SSPT | p-value | IMRT (Gy) | SSPT (Gy) | IMRT (Gy) | SSPT (Gy) | p-value | ||
1 | 3.4 | 21.4 | 19.3 | 18.1 | 15.9 | 0.56 | 0.29 | 0.021 | 24.4 | 16.3 | 35.9 | 20.2 | 0.012 |
2 | 4.8 | 26.4 | 19.1 | 20.8 | 14.2 | 0.49 | 0.30 | 21.4 | 16.4 | 33.1 | 20.1 | ||
3 | 5.1 | 18.7 | 15.9 | 15.5 | 14.5 | 0.46 | 0.25 | 19.8 | 13.6 | 30.3 | 16.6 | ||
4 | 5.4 | 25.4 | 17.8 | 17.9 | 17.9 | 0.40 | 0.24 | 24.2 | 17.7 | 32.8 | 15.2 | ||
5 | 6.3 | 31.2 | 21.2 | 23.2 | 20.2 | 0.47 | 0.33 | 37.9 | 22.4 | 37.9 | 19.9 | ||
6 | 7.8 | 61.8 | 30.0 | 40.9 | 28.3 | 0.70 | 0.47 | < 0.001 | 36.9 | 27.4 | 52.5 | 33.1 | < 0.001 |
7 | 8.2 | 67.5 | 27.3 | 59.7 | 27.3 | 0.72 | 0.49 | 36.1 | 28.1 | 54.5 | 32.5 | ||
8 | 8.3 | 76.9 | 41.2 | 42.7 | 27.7 | 0.62 | 0.32 | 32.7 | 17.4 | 56.7 | 24.2 | ||
9 | 8.7 | 70.0 | 45.6 | 60.4 | 27.9 | 0.75 | 0.53 | 38.3 | 28.6 | 58.1 | 33.3 | ||
10 | 11.1 | 61.3 | 39.8 | 60.2 | 28.2 | 0.76 | 0.44 | 38.8 | 24.4 | 67.9 | 27.3 | ||
11 | 12.1 | 89.5 | 50.9 | 67.3 | 30.9 | 0.83 | 0.57 | 41.9 | 31.7 | 75.4 | 32.4 | ||
12 | 14.6 | 70.9 | 48.2 | 55.3 | 29.7 | 0.73 | 0.45 | 37.1 | 25.6 | 64.2 | 30.4 | ||
13 | 16.1 | 64.7 | 48.5 | 62.4 | 37.9 | 0.86 | 0.55 | 42.4 | 30.3 | 78.4 | 31.5 | ||
ave. | 8.6 | 52.7 | 32.7 | 41.9 | 24.7 | 0.64 | 0.40 | 33.2 | 23.4 | 52.1 | 25.9 |