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Brain Topography
Erschienen in: Brain Topography 3/2017

07.02.2017 | Original Paper

Whole-Brain High-Resolution Structural Connectome: Inter-Subject Validation and Application to the Anatomical Segmentation of the Striatum

verfasst von: Pierre Besson, Nicolas Carrière, S. Kathleen Bandt, Marc Tommasi, Xavier Leclerc, Philippe Derambure, Renaud Lopes, Louise Tyvaert

Erschienen in: Brain Topography | Ausgabe 3/2017

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Abstract

The present study describes extraction of high-resolution structural connectome (HRSC) in 99 healthy subjects, acquired and made available by the Human Connectome Project. Single subject connectomes were then registered to the common surface space to allow assessment of inter-individual reproducibility of this novel technique using a leave-one-out approach. The anatomic relevance of the surface-based connectome was examined via a clustering algorithm, which identified anatomic subdivisions within the striatum. The connectivity of these striatal subdivisions were then mapped on the cortical and other subcortical surfaces. Findings demonstrate that HRSC analysis is robust across individuals and accurately models the actual underlying brain networks related to the striatum. This suggests that this method has the potential to model and characterize the healthy whole-brain structural network at high anatomic resolution.
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Metadaten
Titel
Whole-Brain High-Resolution Structural Connectome: Inter-Subject Validation and Application to the Anatomical Segmentation of the Striatum
verfasst von
Pierre Besson
Nicolas Carrière
S. Kathleen Bandt
Marc Tommasi
Xavier Leclerc
Philippe Derambure
Renaud Lopes
Louise Tyvaert
Publikationsdatum
07.02.2017
Verlag
Springer US
Erschienen in
Brain Topography / Ausgabe 3/2017
Print ISSN: 0896-0267
Elektronische ISSN: 1573-6792
DOI
https://doi.org/10.1007/s10548-017-0548-0

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