nach oben

Archives of Gynecology and Obstetrics

Erschienen in:

01.09.2008 | Original Article

Young maternal age and risk of intrapartum stillbirth

verfasst von: Roneé E. Wilson, Amina P. Alio, Russell S. Kirby, Hamisu M. Salihu

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 3/2008

Einloggen, um Zugang zu erhalten

Abstract

Objectives

To determine the risk of intrapartum stillbirth among teen mothers.

Methods

The Missouri maternally linked data containing births from 1978 to 1997 were analyzed. The study group (teen mothers) was sub-divided into younger (<15 years) and older (15–19 years) teenagers. Women aged 20–24 were the referent category. We used Kaplan–Meier product-limit estimator to calculate the cumulative probability of death for each group and the Cox Proportional Hazards Regression models to obtain adjusted hazards ratios.

Results

The rate of antepartum and intrapartum stillbirth among teenagers was 3.8 per 1,000 and 1.0 per 1,000, respectively, compared to 3.5 per 1,000 and 0.8 per 1,000 among the reference group. The adjusted risk of intrapartum stillbirth was more than 4 times as high among younger teens (adjusted hazard ratio [AHR] 4.3 [95% CI 4.0–4.7]) and 50% higher among older teens (AHR 1.5 [95% CI 1.2–1.8]). The risk of intrapartum stillbirth occurred in a dose-dependent fashion, with risk increasing as maternal age decreased (P < 0.01).

Conclusion

Teenagers are at an increased risk of stillbirth, with the greatest risk disparity occurring intrapartum, especially among younger teens. This new information is potentially useful for targeting intervention measures aimed at improving in utero fetal survival among pregnant women at the lower extreme of the maternal age spectrum.

Fraser AM, Brockert JE, Ward RH (1995) Association of young maternal age with adverse reproductive outcomes. N Engl J Med 332(17):1113–1117PubMedCrossRef

Olausson PO, Cnattingius S, Haglund B (1999) Teenage pregnancies and risk of late fetal death and infant mortality. Br J Obstet Gynaecol 106(2):116–121PubMed

Hediger ML, Scholl TO, Schall JI et al (1997) Young maternal age and preterm labor. Ann Epidemiol 7:400–406PubMedCrossRef

Haldre K, Rahu, Karro H, Rahu M (2006) Is a poor pregnancy outcome related to young maternal age? A study of teenagers in Estonia during the period of major socio-economic changes (from 1992 to 2002). Eur J Obstet Gynecol Reprod Biol 131:45–51PubMedCrossRef

Salihu HM, Sharma PP, Ekundayo OJ et al (2006) Childhood pregnancy (10–14 years old) and risk of stillbirth in singletons and twins. J Pediatr 148:522–526PubMedCrossRef

Martin J, Curtin S, Saulnier M et al (2003) Development of the matched multiple birth file. 1995–1998 matched multiple birth dataset. NCHS CD-ROM series 21, no. 13a. National Center for Health Statistics, Hyattsville

Herman AA, McCarthy BJ, Bakewell JM et al (1997) Data linkage methods used in maternally-linked birth and infant death surveillance data sets from the United States (Georgia, Missouri, Utah and Washington State), Israel, Norway, Scotland and Western Australia. Paediatr Perinat Epidemiol 11:5–22PubMedCrossRef

Salihu HM, Sharma PP, Peters S (2006) Twinning and risk of stillbirth subtypes in pediatric mothers. Twin Res Hum Genet 9:673–676PubMedCrossRef

Alexander GR, Kotelchuck M (1996) Quantifying the adequacy of prenatal care: a comparison of indices. Public Health Rep 111:408–418PubMed

10.

Alexander GR, Cornely DA (1987) Prenatal care utilization: its measurement and relationship to pregnancy outcome. Am J Prev Med 3:243–253PubMed

11.

Smith GCS, Pell JP (2001) Teenage pregnancy and risk of adverse perinatal outcomes associated with first and second births: population based retrospective cohort study. BMJ 323:476–479PubMedCrossRef

12.

Alexander MR, Salihu HM, Rouse DJ (2004) Survival of triplets who are born to teen mothers in the United States. Am J Obstet Gynecol 191:2097–2102PubMedCrossRef

13.

Naeye RL (1981) Teenaged and pre-teenaged pregnancies: consequences of the fetal-maternal competition for nutrients. Pediatrics 67:146–150PubMed

14.

Scholl TO, Hediger ML, Ances IG et al (1988) Growth during early teenage pregnancies. Lancet 2:701–702CrossRef

15.

Mangold WD (1983) Age of mother and pregnancy outcome in the 1981 Arkansas birth cohort. Soc Biol 30:205–210PubMed

16.

DuPlessis HM, Bell R, Richards T (1997) Adolescent pregnancy: understanding the impact of age and race on outcomes. J Adolesc Health 20:187–197PubMedCrossRef

17.

Elster AB (1984) The effect of maternal age, parity, and prenatal care on perinatal outcome in adolescent mothers. Am J Obstet Gynecol 149:845–847PubMed

18.

Berenson AB, Wiemann CM, McCombs SL (1997) Adverse perinatal outcomes in young adolescents. J Reprod Med 42:559–564PubMed

19.

Ekwo EE, Moawad A (2000) Maternal age and preterm births in a black population. Pediatr Perinat Epidemiol 14:145–151CrossRef

20.

Stubblefield PG, Berek JS (1980) Perinatal mortality in term and postterm births. Obstet Gynecol 56:676–682PubMed

21.

Smith CS (2005) Estimating the risks of perinatal death. Am J Obstet Gyn 192:17–22CrossRef

22.

Kirby RS (1993) The coding of underlying cause of death from fetal death certificates: issues and policy considerations. Am J Public Health 83:1088–1091PubMedCrossRef

23.

Sharma PP, Salihu HM, Kirby RS (2007) Stillbirth recurrence in a population of relatively low-risk mothers. Paediatr Perinat Epidemiol 21:24–30PubMedCrossRef

24.

Greenwood R, Samms-Vaughan M,Golding J et al (1994) Past obstetric history and risk of perinatal death in Jamaica. Paediatr Perinat Epidemiol 8(Suppl 1):40–53PubMedCrossRef

25.

Samueloff A, Xenakis EM, Berkus MD et al (1993) Recurrent stillbirth: significance and characteristics. J Reprod Med 38:883–886PubMed

26.

Frias AE Jr, Luikenaar RA, Sullivan AE et al (2004) Poor obstetric outcome in subsequent pregnancies in women with prior fetal death. Obstet Gynecol 104:521–526PubMed

27.

Freeman RK, Dorchester W, Anderson G et al (1985) The significance of a previous stillbirth. Am J Obstet Gynecol 151:7–13PubMed

28.

Salihu HM (2007) Fetal death repetition: the event memory hypothesis. Med Hypotheses (epub ahead of print)

Titel: Young maternal age and risk of intrapartum stillbirth
verfasst von: Roneé E. Wilson
Amina P. Alio
Russell S. Kirby
Hamisu M. Salihu
Publikationsdatum: 01.09.2008
Verlag: Springer-Verlag
Erschienen in: Archives of Gynecology and Obstetrics / Ausgabe 3/2008
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-007-0557-4

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.

Newsletter bestellen

Springer Medizin

Young maternal age and risk of intrapartum stillbirth

Abstract

Objectives

Methods

Results

Conclusion

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Update Gynäkologie

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusion

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 3/2008

Atypical case of reversible posterior leucoencephalopathy syndrome associated with puerperal HELLP syndrome

Appendiceal endometriosis: two case reports

Giant lipoleiomyoma of the uterine corpus

Lipoadenofibroma of the endometrium: a rare variant of benign mullerian mixed tumor

Diagnostic value of hysteroscopy and hysterosonography in endometrial abnormalities in asymptomatic postmenopausal women

Quality of life and acute toxicity of radiotherapy in women with gynecologic cancer: a prospective longitudinal study

Neu im Fachgebiet Gynäkologie und Geburtshilfe

Hirsutismus bei PCOS: Laser- und Lichttherapien helfen

ICI-Therapie in der Schwangerschaft wird gut toleriert

Weniger postpartale Depressionen nach Esketamin-Einmalgabe

Bei RSV-Impfung vor 60. Lebensjahr über Off-Label-Gebrauch aufklären!

Update Gynäkologie