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Erschienen in: Der Onkologe 2/2019

18.01.2019 | Zervixkarzinom | CME

Management des lokal fortgeschrittenen Zervixkarzinoms

verfasst von: PD Dr. Christof Schäfer, M. Bioethics, MA, MBM, Dr. Gabor Galli, Dr. Carsten Scholz

Erschienen in: Die Onkologie | Ausgabe 2/2019

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Zusammenfassung

Das lokal fortgeschrittene Zervixkarzinom erfordert eine besonders intensive interdisziplinäre Absprache. In der Definition des Stadiums spielen neben der klassischen FIGO-Einteilung (FIGO: „Fédération Internationale de Gynécologie et d’Obstétrique“) Risikofaktoren eine wichtige Rolle. Dabei ist der Lymphknotenstatus entscheidend. In frühen Stadien wird operativ vorgegangen, bei weiter fortgeschrittener Erkrankung bis hin zum Stadium IVA wird die Radiochemotherapie präferiert. In jedem Fall ist eine frühzeitige Besprechung innerhalb eines Tumorboards erforderlich. Kontroversen betreffen z. B. den Einsatz moderner bildgebender Verfahren, die Therapie bei befallenen paraaortalen Lymphknoten, den Stellenwert einer neoadjuvanten Chemotherapie und die Versuche, die klassische Radiochemotherapie mit Cisplatin zu intensivieren. Der Artikel gibt dazu einen Überblick, unter besonderer Berücksichtigung aktueller Studiendaten und unter Bezugnahme auf die derzeit gültigen Leitlinien.
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Metadaten
Titel
Management des lokal fortgeschrittenen Zervixkarzinoms
verfasst von
PD Dr. Christof Schäfer, M. Bioethics, MA, MBM
Dr. Gabor Galli
Dr. Carsten Scholz
Publikationsdatum
18.01.2019
Verlag
Springer Medizin
Erschienen in
Die Onkologie / Ausgabe 2/2019
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI
https://doi.org/10.1007/s00761-018-0517-6

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