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Pediatric Nephrology

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01.02.2006 | Educational Feature

A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H

verfasst von: Hyewon Hahn, Eun Young Um, Young Seo Park, Hae Il Cheong

Erschienen in: Pediatric Nephrology | Ausgabe 2/2006

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Abstract

We report a case of sporadic atypical hemolytic uremic syndrome (HUS) with a transient decrease in complement factor H. Referred for hemolysis and azotemia without diarrhea prodrome, this 31-month-old boy showed a decreased complement 3 (C3) and complement factor H (FH) level. However, the factor H gene (HF1) mutation was missing. After the hemolysis was controlled with plasma infusion, the C3 and FH levels recovered. The patient’s renal function fully recovered and remained normal, and there was no recurrence of the HUS.

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Titel: A case of atypical hemolytic uremic syndrome with a transient decrease in complement factor H
verfasst von: Hyewon Hahn
Eun Young Um
Young Seo Park
Hae Il Cheong
Publikationsdatum: 01.02.2006
Verlag: Springer-Verlag
Erschienen in: Pediatric Nephrology / Ausgabe 2/2006
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-005-2108-1

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