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European Archives of Psychiatry and Clinical Neuroscience

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01.04.2013 | Original Paper

A further evaluation of decision-making under risk and under ambiguity in schizophrenia

verfasst von: Guillaume Fond, Sophie Bayard, Delphine Capdevielle, Jonathan Del-Monte, Nawale Mimoun, Alexandra Macgregor, Jean-Philippe Boulenger, Marie-Christine Gely-Nargeot, Stéphane Raffard

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 3/2013

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Abstract

Abnormal decision-making has been described as a key-concept to understand some behavioral disturbances in schizophrenia. However, whether schizophrenia patients display impairments in profitable decision-making on experimental designs is still controversial (1) to assess performance on decision-making paradigms under ambiguity and under risk conditions in a large sample of schizophrenia patients and (2) to study the impact of clinical variables on decision-making performance in schizophrenia. The Iowa gambling task (IGT) and the game of dice task (GDT) were administered to assess, respectively, decision-making under ambiguity and under risk in 63 schizophrenia patients and 67 healthy controls. In addition, clinical variables (e.g., schizophrenic symptoms, self-reported depression, and impulsivity) were evaluated using appropriate questionnaires the same day. Pharmacological treatments were reported. Schizophrenia patients had impaired performances on both IGT and GDT tasks. No correlation between the decision-making tasks performance and clinical variables was found. Lower gains on the GDT were associated with executive dysfunctioning in schizophrenia. These findings give evidence that schizophrenia patients display impairments in both decision-making under ambiguity and under risk.

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Titel: A further evaluation of decision-making under risk and under ambiguity in schizophrenia
verfasst von: Guillaume Fond
Sophie Bayard
Delphine Capdevielle
Jonathan Del-Monte
Nawale Mimoun
Alexandra Macgregor
Jean-Philippe Boulenger
Marie-Christine Gely-Nargeot
Stéphane Raffard
Publikationsdatum: 01.04.2013
Verlag: Springer-Verlag
Erschienen in: European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 3/2013
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-012-0330-y

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