Introduction
Method
Search strategy and inclusion criteria
Data extraction
Quality assessment
Statistical analysis
Results
Characteristics of the included studies
Study name | Sample size | Intervention | Observation time | Surgical type | Monitoring of AF | Aderverse drug reaction (E/C) | Main terminal point | AF before surgery (E/C) |
---|---|---|---|---|---|---|---|---|
Bessissow [17] | 100 | 0.6 mg before operation, 0.6 mg bid for 9 day after operation | 30 days | Lung resection surgery | (ECG) was per-formed once a day for the first 3 days. Then 30-day follow-up | 5/1 | POAF | 0/0 |
Deftereos [15] | 161 | 0.5 mg bid for 3 months | 3 months | Pulmonary Vein Isolation | Electrogram obtained during patient visits at the arrhythmia clinic | 7/1 | Recurrence of AF | All/All |
Deftereos [16] | 206 | 0.5 mg bid for 3 months | 3 months | Pulmonary Vein Isolation | Not report | 10/2 | Recurrence of AF | All/All |
Imazio [19] | 336 | 0.5 mg bid for 1 month | 1 month | CABG, aortic surgery, valvular surgery, combined | Continuous ECG monitoring and 12-lead ECG recordings | 16/8 | Rate of POAF on placebo/colchicine treatment | 8/11 |
Imazio [18] | 360 | 0.5 mg bid for 1 month | 3 months | CABG, aortic surgery, valvular surgery, combined | Continuous ECG monitoring and 12-lead ECG recordings | 36/21 | AF | 18/15 |
Sarzaeem [23] | 216 | 24 h before surgery 2 mg; 0.5 mg bid for 1 week after operation | In hospital | CABG | Continuous ECG monitoring while in ICU, and daily 12 lead ECG while on the regular floor | Not report | AF | Not recorded |
Tabbalat [22] | 360 | 0.5 mg bid after operation was taken in hospital until discharge | In hospital | CABG or other open heart surgery | Daily electrocardiograms (ECGs) until discharge | 55/14 | AF | Not recorded |
Tabbalat [21] | 152 | 0.5 mg qd after operation | In hospital | Open heart surgery | Daily electrocardiograms (ECGs) until discharge | 2/2 | POAF | Not recorded |
Zarpelon [20] | 140 | After operation 0.5 mg bid was taken in hospital until discharge | In hospital | Open heart surgery-Myocardial Revascularization | continuous cardiac monitoring and 12-lead electrocardiogram during ICU stay | 19/6 | AF | Not recorded |