nach oben

Erschienen in:

12.04.2015 | Original Article

A premammillary lateral hypothalamic nuclear complex responds to hedonic but not aversive tastes in the male rat

Erschienen in: Brain Structure and Function | Ausgabe 4/2016

Einloggen, um Zugang zu erhalten

Abstract

The lateral hypothalamic area (LHA) has two major roles: arousal/waking and food intake controls. Here, it is shown that a premammillary part of the LHA is neurochemically and cytoarchitectonically distinct from the tuberal LHA in male rats. This part contains nuclear masses, namely the parasubthalamic nucleus and the calbindin nucleus, involved in pathways that predict its participation in the control of food intake. Analyzing c-Fos expression in experiments related to feeding behavior, this region responded specifically to the ingestion of palatable nutriments.

Anand BK, Brobeck JR (1951) Hypothalamic control of food intake in rats and cats. Yale J Biol Med 24(2):123–140PubMedPubMedCentral

Aponte Y, Atasoy D, Sternson SM (2011) AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat Neurosci 14(3):351–355. doi:10.1038/nn.2739 CrossRefPubMedPubMedCentral

Bester H, Besson JM, Bernard JF (1997) Organization of efferent projections from the parabrachial area to the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J Comp Neurol 383(3):245–281CrossRefPubMed

Bilella A, Alvarez-Bolado G, Celio MR (2014) Coaxiality of Foxb1- and parvalbumin-expressing neurons in the lateral hypothalamic PV1-nucleus. Neurosci Lett 566:111–114. doi:10.1016/j.neulet.2014.02.028 CrossRefPubMed

Bourgeais L, Gauriau C, Bernard JF (2001) Projections from the nociceptive area of the central nucleus of the amygdala to the forebrain: a PHA-L study in the rat. Eur J Neurosci 14(2):229–255CrossRefPubMed

Carter ME, Soden ME, Zweifel LS, Palmiter RD (2013) Genetic identification of a neural circuit that suppresses appetite. Nature 503(7474):111–114. doi:10.1038/nature12596 CrossRefPubMedPubMedCentral

Carter ME, Han S, Palmiter RD (2015) Parabrachial calcitonin gene-related Peptide neurons mediate conditioned taste aversion. J Neurosci 35(11):4582–4586. doi:10.1523/jneurosci.3729-14.2015 CrossRefPubMedPubMedCentral

Celio MR (1990) Calbindin D-28 k and parvalbumin in the rat nervous system. Neuroscience 35(2):375–475CrossRefPubMed

Cole S, Hobin MP, Petrovich GD (2015) Appetitive associative learning recruits a distinct network with cortical, striatal, and hypothalamic regions. Neuroscience 286:187–202. doi:10.1016/j.neuroscience.2014.11.026 CrossRefPubMed

Comoli E, Ribeiro-Barbosa ER, Negrao N, Goto M, Canteras NS (2005) Functional mapping of the prosencephalic systems involved in organizing predatory behavior in rats. Neuroscience 130(4):1055–1067. doi:10.1016/j.neuroscience.2004.10.020 CrossRefPubMed

Cui H, Sohn JW, Gautron L, Funahashi H, Williams KW, Elmquist JK, Lutter M (2012) Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. J Comp Neurol 520(18):4168–4183. doi:10.1002/cne.23145 CrossRefPubMedPubMedCentral

Cvetkovic V, Poncet F, Fellmann D, Griffond B, Risold PY (2003) Diencephalic neurons producing melanin-concentrating hormone are influenced by local and multiple extra-hypothalamic tachykininergic projections through the neurokinin 3 receptor. Neuroscience 119(4):1113–1145CrossRefPubMed

Cvetkovic V, Brischoux F, Jacquemard C, Fellmann D, Griffond B, Risold PY (2004) Characterization of subpopulations of neurons producing melanin-concentrating hormone in the rat ventral diencephalon. J Neurochem 91(4):911–919. doi:10.1111/j.1471-4159.2004.02776.x CrossRefPubMed

Dobolyi A, Irwin S, Makara G, Usdin TB, Palkovits M (2005) Calcitonin gene-related peptide-containing pathways in the rat forebrain. J Comp Neurol 489(1):92–119. doi:10.1002/cne.20618 CrossRefPubMed

Esclapez M, Tillakaratne NJ, Tobin AJ, Houser CR (1993) Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods. J Comp Neurol 331(3):339–362. doi:10.1002/cne.903310305 CrossRefPubMed

Goto M, Swanson LW (2004) Axonal projections from the parasubthalamic nucleus. J Comp Neurol 469(4):581–607. doi:10.1002/cne.11036 CrossRefPubMed

Grove EA (1988) Efferent connections of the substantia innominata in the rat. J Comp Neurol 277(3):347–364. doi:10.1002/cne.902770303 CrossRefPubMed

Hahn JD (2010) Comparison of melanin-concentrating hormone and hypocretin/orexin peptide expression patterns in a current parceling scheme of the lateral hypothalamic zone. Neurosci Lett 468(1):12–17. doi:10.1016/j.neulet.2009.10.047 CrossRefPubMedPubMedCentral

Huang T, Yan J, Kang Y (2003) Role of the central amygdaloid nucleus in shaping the discharge of gustatory neurons in the rat parabrachial nucleus. Brain Res Bull 61(4):443–452CrossRefPubMed

Jennings JH, Rizzi G, Stamatakis AM, Ung RL, Stuber GD (2013) The inhibitory circuit architecture of the lateral hypothalamus orchestrates feeding. Science (New York, NY) 341(6153):1517–1521. doi:10.1126/science.1241812 CrossRef

Krause JE, Chirgwin JM, Carter MS, Xu ZS, Hershey AD (1987) Three rat preprotachykinin mRNAs encode the neuropeptides substance P and neurokinin A. Proc Natl Acad Sci USA 84(3):881–885CrossRefPubMedPubMedCentral

Laque A, Zhang Y, Gettys S, Nguyen TA, Bui K, Morrison CD, Munzberg H (2013) Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action. Am J Physiol Endocrinol Metab 304(9):E999–E1011. doi:10.1152/ajpendo.00643.2012 CrossRefPubMedPubMedCentral

Larsen PJ (1992) Distribution of substance P-immunoreactive elements in the preoptic area and the hypothalamus of the rat. J Comp Neurol 316(3):287–313. doi:10.1002/cne.903160304 CrossRefPubMed

Leinninger GM et al (2011) Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab 14(3):313–323. doi:10.1016/j.cmet.2011.06.016 CrossRefPubMedPubMedCentral

Mathur BN, Caprioli RM, Deutch AY (2009) Proteomic analysis illuminates a novel structural definition of the claustrum and insula. Cereb Cortex (New York, NY 1991) 19(10):2372–2379. doi:10.1093/cercor/bhn253 CrossRef

Merchenthaler I, Lopez FJ, Negro-Vilar A (1993) Anatomy and physiology of central galanin-containing pathways. Prog Neurobiol 40(6):711–769CrossRefPubMed

Meszar Z, Girard F, Saper CB, Celio MR (2012) The lateral hypothalamic parvalbumin-immunoreactive (PV1) nucleus in rodents. J Comp Neurol 520(4):798–815. doi:10.1002/cne.22789 CrossRefPubMedPubMedCentral

Nambu T, Sakurai T, Mizukami K, Hosoya Y, Yanagisawa M, Goto K (1999) Distribution of orexin neurons in the adult rat brain. Brain Res 827(1–2):243–260. doi:10.1016/s0006-8993(99)01336-0 CrossRefPubMed

Norgren R (1995) Gustatory system. In: Paxinos G (ed) The rat nervous system. Academic Press, San Diego, pp 751–771

Paxinos G, Watson CH (1986) The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, Sydney

Paxinos G, Watson C (2005) The rat brain in stereotaxic coordinates, vol 5. Elsevier, New York

Petrovich GD, Risold PY, Swanson LW (1996) Organization of projections from the basomedial nucleus of the amygdala: a PHAL study in the rat. J Comp Neurol 374(3):387–420. doi:10.1002/(SICI)1096-9861(19961021)374:3<387:AID-CNE6>3.0.CO;2-Y CrossRefPubMed

Petrovich GD, Setlow B, Holland PC, Gallagher M (2002) Amygdalo-hypothalamic circuit allows learned cues to override satiety and promote eating. J Neurosci 22(19):8748–8753PubMed

Price JL, Slotnick BM, Revial MF (1991) Olfactory projections to the hypothalamus. J Comp Neurol 306(3):447–461. doi:10.1002/cne.903060309 CrossRefPubMed

Puelles L, Martinez-de-la-Torre M, Bardet S, JLR R (2012) Hypothalamus. In: The mouse nervous system. Elsevier, pp 221–312

Qu D et al (1996) A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380(6571):243–247. doi:10.1038/380243a0 CrossRefPubMed

Risold PY, Swanson LW (1995) Cajal’s nucleus of the stria medullaris: characterization by in situ hybridization and immunohistochemistry for enkephalin. J Chem Neuroanat 9(4):235–240CrossRefPubMed

Risold PY, Swanson LW (1996) Structural evidence for functional domains in the rat hippocampus. Science (New York, NY) 272(5267):1484–1486CrossRef

Risold PY, Swanson LW (1997) Chemoarchitecture of the rat lateral septal nucleus. Brain Res Rev 24(2–3):91–113CrossRefPubMed

Risold PY, Fellmann D, Rivier J, Vale W, Bugnon C (1992) Immunoreactivities for antisera to three putative neuropeptides of the rat melanin-concentrating hormone precursor are coexpressed in neurons of the rat lateral dorsal hypothalamus. Neurosci Lett 136(2):145–149CrossRefPubMed

Sakurai T et al (1998) Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92(4):573–585. doi:10.1016/s0092-8674(00)80949-6 CrossRefPubMed

Saper CB, Chou TC, Elmquist JK (2002) The need to feed: homeostatic and hedonic control of eating. Neuron 36(2):199–211CrossRefPubMed

Shin JW, Geerling JC, Stein MK, Miller RL, Loewy AD (2011) FoxP2 brainstem neurons project to sodium appetite regulatory sites. J Chem Neuroanat 42(1):1–23. doi:10.1016/j.jchemneu.2011.05.003 CrossRefPubMedPubMedCentral

Shirasu M, Takahashi T, Yamamoto T, Itoh K, Sato S, Nakamura H (2011) Direct projections from the central amygdaloid nucleus to the mesencephalic trigeminal nucleus in rats. Brain Res 1400:19–30. doi:10.1016/j.brainres.2011.05.026 CrossRefPubMed

Smith KS, Berridge KC (2005) The ventral pallidum and hedonic reward: neurochemical maps of sucrose “liking” and food intake. J Neurosci 25(38):8637–8649. doi:10.1523/jneurosci.1902-05.2005 CrossRefPubMed

Swanson LW (1998) Brain Maps: structure of the rat brain, 2nd edn. Elsevier, Amsterdam

Swanson LW (2004) Brain Maps: Structure of the rat brain, vol 3. Elsevier, New York

Swanson LW, Sanchez-Watts G, Watts AG (2005) Comparison of melanin-concentrating hormone and hypocretin/orexin mRNA expression patterns in a new parceling scheme of the lateral hypothalamic zone. Neurosci Lett 387(2):80–84. doi:10.1016/j.neulet.2005.06.066 CrossRefPubMed

Valdes JL, Sanchez C, Riveros ME, Blandina P, Contreras M, Farias P, Torrealba F (2010) The histaminergic tuberomammillary nucleus is critical for motivated arousal. Eur J Neurosci 31(11):2073–2085. doi:10.1111/j.1460-9568.2010.07241.x CrossRefPubMed

Wang PY, Zhang FC (1995) Outline and atlas of learning rat brain slices. Westnorth University Press, China

Yamamoto T, Matsuo R, Kiyomitsu Y, Kitamura R (1989) Response properties of lateral hypothalamic neurons during ingestive behavior with special reference to licking of various taste solutions. Brain Res 481(2):286–297CrossRefPubMed

Yasui Y, Breder CD, Saper CB, Cechetto DF (1991) Autonomic responses and efferent pathways from the insular cortex in the rat. J Comp Neurol 303(3):355–374. doi:10.1002/cne.903030303 CrossRefPubMed

Titel: A premammillary lateral hypothalamic nuclear complex responds to hedonic but not aversive tastes in the male rat
Publikationsdatum: 12.04.2015
Erschienen in: Brain Structure and Function / Ausgabe 4/2016
Print ISSN: 1863-2653
Elektronische ISSN: 1863-2661
DOI: https://doi.org/10.1007/s00429-015-1038-3

Leitlinien kompakt für die Neurologie

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Neurologie

25.04.2024 | Hypotonie | Nachrichten

Update Neurologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Springer Medizin

A premammillary lateral hypothalamic nuclear complex responds to hedonic but not aversive tastes in the male rat

Abstract

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Frühe Alzheimertherapie lohnt sich

Viel Bewegung in der Parkinsonforschung

Demenzkranke durch Antipsychotika vielfach gefährdet

Update Neurologie

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2016

Navigating toward a novel environment from a route or survey perspective: neural correlates and context-dependent connectivity

Kisspeptin signaling in the amygdala modulates reproductive hormone secretion

Neurons in the lateral part of the lumbar spinal cord show distinct novel axon trajectories and are excited by short propriospinal ascending inputs

Novel subventricular zone early progenitor cell-specific adenovirus for in vivo therapy of central nervous system disorders reinforces brain stem cell heterogeneity

Frontotemporal correlates of impulsivity and machine learning in retired professional athletes with a history of multiple concussions

The RNA-binding protein Celf6 is highly expressed in diencephalic nuclei and neuromodulatory cell populations of the mouse brain

Leitlinien kompakt für die Neurologie

Neu im Fachgebiet Neurologie

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

Frühe Alzheimertherapie lohnt sich

Viel Bewegung in der Parkinsonforschung

Demenzkranke durch Antipsychotika vielfach gefährdet

Update Neurologie