Skip to main content
Erschienen in: Journal of Interventional Cardiac Electrophysiology 2/2009

01.03.2009

A prospective randomised comparison of large-tip cryoablation and 8-mm-tip radiofrequency catheter ablation of atrial flutter

verfasst von: Helena Malmborg, Stefan Lönnerholm, Carina Blomström Lundqvist

Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 2/2009

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Although radiofrequency (RF) energy is routinely used for tricuspid isthmus (TI) ablation, it is often associated with discomfort. The paucity of studies comparing the feasibility and efficacy of cryo- versus RF energy for TI-ablation urged us to conduct a prospective, randomised trial.

Methods

Forty patients with atrial flutter (AFl) were randomised to RF- or cryoenergy for TI-ablation. Perceived pain was scored from 1 to 10 on a Visual Analogue Scale.

Results

Significantly lower pain scores were recorded for cryoablation versus RF ablation (0.96 ± 0.73 versus 4.2 ± 2.4, p = 0.00004). Cryoablation was associated with significantly longer procedure duration and ablation time (137 ± 35 versus 111 ± 29 min, p = 0.016 and 81 ± 40 versus 48 ± 30 min, p = 0.007) and lower acute success rate (56% versus 100%, p = 0.001) than RF ablation. The recurrence of AFl was 20% (cryo) versus 15% (RF; p = 0.45) after a mean of 15.1 months follow-up.

Conclusion

Cryoablation results in significantly less pain and discomfort compared to RF ablation of AFl, which is offset by the significantly lower acute success rate.
Literatur
1.
Zurück zum Zitat Anselme, F., Saoudi, N., Poty, H., Douillet, R., & Cribier, A. (1999). Radiofrequency catheter ablation of common atrial flutter: significance of palpitations and quality-of-life evaluation in patients with proven isthmus block. Circulation, 99, 534–540.PubMed Anselme, F., Saoudi, N., Poty, H., Douillet, R., & Cribier, A. (1999). Radiofrequency catheter ablation of common atrial flutter: significance of palpitations and quality-of-life evaluation in patients with proven isthmus block. Circulation, 99, 534–540.PubMed
2.
Zurück zum Zitat Natale, A., Newby, K. H., Pisano, E., Leonelli, F., Fanell, R., Potenza, D., et al. (2000). Prospective randomized comparison of antiarrhythmic therapy versus first-line radiofrequency ablation in patients with atrial flutter. Journal of the American College of Cardiology, 35, 1898–1904.PubMedCrossRef Natale, A., Newby, K. H., Pisano, E., Leonelli, F., Fanell, R., Potenza, D., et al. (2000). Prospective randomized comparison of antiarrhythmic therapy versus first-line radiofrequency ablation in patients with atrial flutter. Journal of the American College of Cardiology, 35, 1898–1904.PubMedCrossRef
3.
Zurück zum Zitat Da Costa, A., Thévenin, J., Roche, F., Romeyer-Bouchard, C., Abdellaoui, L., Messier, M., et al. (2006). Result from the Loire-Ardèche-Drome-Isère-Puy-dr-Dome (LAPID) trial on atrial flutter, a multicentre study comparing amiodarone and radiofrequency ablation after the first episode of symptomatic atrial flutter. Circulation, 114, 1676–1681.PubMedCrossRef Da Costa, A., Thévenin, J., Roche, F., Romeyer-Bouchard, C., Abdellaoui, L., Messier, M., et al. (2006). Result from the Loire-Ardèche-Drome-Isère-Puy-dr-Dome (LAPID) trial on atrial flutter, a multicentre study comparing amiodarone and radiofrequency ablation after the first episode of symptomatic atrial flutter. Circulation, 114, 1676–1681.PubMedCrossRef
4.
Zurück zum Zitat Calkins, H., Canby, R., Weiss, R., Taylor, G., Wells, P., Chinitz, L., et al. (2004). Results of catheter ablation of typical atrial flutter. The American Journal of Cardiology, 94, 437–442.PubMedCrossRef Calkins, H., Canby, R., Weiss, R., Taylor, G., Wells, P., Chinitz, L., et al. (2004). Results of catheter ablation of typical atrial flutter. The American Journal of Cardiology, 94, 437–442.PubMedCrossRef
5.
Zurück zum Zitat Gilligan, D. M., Zakaib, J. S., Fuller, I., Shepard, R. K., Dan, D., Wood, M. A., et al. (2003). Long-term outcome of patients after successful radiofrequency ablation for typical atrial flutter. Pacing and Clinical Electrophysiology, 26, 53–58.PubMedCrossRef Gilligan, D. M., Zakaib, J. S., Fuller, I., Shepard, R. K., Dan, D., Wood, M. A., et al. (2003). Long-term outcome of patients after successful radiofrequency ablation for typical atrial flutter. Pacing and Clinical Electrophysiology, 26, 53–58.PubMedCrossRef
6.
Zurück zum Zitat Hsieh, M. H., Tai, C. H., Chiang, C. E., Tsai, C. F., Yu, W. C., Chen, Y. J., et al. (2002). Recurrent atrial flutter and atrial fibrillation after catheter ablation of the cavotricuspid isthmus: a very long follow-up of 333 patients. Journal of Interventional Cardiac Electrophysiology, 7, 225–231.PubMedCrossRef Hsieh, M. H., Tai, C. H., Chiang, C. E., Tsai, C. F., Yu, W. C., Chen, Y. J., et al. (2002). Recurrent atrial flutter and atrial fibrillation after catheter ablation of the cavotricuspid isthmus: a very long follow-up of 333 patients. Journal of Interventional Cardiac Electrophysiology, 7, 225–231.PubMedCrossRef
7.
Zurück zum Zitat Timmermans, C., Ayers, G. M., Crijns, H. J. G. M., & Rodriguez, L. M. (2003). Randomized study comparing radiofrequency ablation with cryoablation for the treatment of atrial flutter with emphasis on pain perception. Circulation, 107, 1250–1252.PubMedCrossRef Timmermans, C., Ayers, G. M., Crijns, H. J. G. M., & Rodriguez, L. M. (2003). Randomized study comparing radiofrequency ablation with cryoablation for the treatment of atrial flutter with emphasis on pain perception. Circulation, 107, 1250–1252.PubMedCrossRef
8.
Zurück zum Zitat Collins, N. J., Barlow, M., Varghese, P., & Leitch, J. (2006). Cryoablation versus radiofrequency ablation in the treatment of atrial flutter trial (CRAAFT). Journal of Interventional Cardiac Electrophysiology, 16, 1–5.PubMedCrossRef Collins, N. J., Barlow, M., Varghese, P., & Leitch, J. (2006). Cryoablation versus radiofrequency ablation in the treatment of atrial flutter trial (CRAAFT). Journal of Interventional Cardiac Electrophysiology, 16, 1–5.PubMedCrossRef
9.
Zurück zum Zitat Manusama, R., Timmermans, C., Limon, F., Philippens, S., Crijns, H., & Rodriguez, L. M. (2004). Catheter-based cryoablation permanently cures patients with common atrial flutter. Circulation, 109, 1636–1639.PubMedCrossRef Manusama, R., Timmermans, C., Limon, F., Philippens, S., Crijns, H., & Rodriguez, L. M. (2004). Catheter-based cryoablation permanently cures patients with common atrial flutter. Circulation, 109, 1636–1639.PubMedCrossRef
10.
Zurück zum Zitat Kuniss, M., Kurzidim, K., Greiss, H., Berkowitsch, A., Sperzel, J., Hamm, C., et al. (2006). Acute success and persistence of bidirectional conduction block in the cavotricuspid isthmus one month past cryocatheter ablation of common atrial flutter. Pacing and Clinical Electrophysiology, 29, 146–152.PubMedCrossRef Kuniss, M., Kurzidim, K., Greiss, H., Berkowitsch, A., Sperzel, J., Hamm, C., et al. (2006). Acute success and persistence of bidirectional conduction block in the cavotricuspid isthmus one month past cryocatheter ablation of common atrial flutter. Pacing and Clinical Electrophysiology, 29, 146–152.PubMedCrossRef
11.
Zurück zum Zitat Montenero, A. S., Bruno, N., Antonelli, A., Mangiameli, D., Barbieri, L., Andrew, P., et al. (2005). Long term efficacy of cryocatheter ablation for the treatment of atrial flutter: Result from a repeat electrophysiologic study. Journal of the American College of Cardiology, 45, 573–580.PubMedCrossRef Montenero, A. S., Bruno, N., Antonelli, A., Mangiameli, D., Barbieri, L., Andrew, P., et al. (2005). Long term efficacy of cryocatheter ablation for the treatment of atrial flutter: Result from a repeat electrophysiologic study. Journal of the American College of Cardiology, 45, 573–580.PubMedCrossRef
12.
Zurück zum Zitat Montenero, A. S., Bruno, N., Antonelli, A., Mangiameli, D., Barbieri, L., Andrew, P., et al. (2005). Comparison between a 7 French 6 mm tip cryothermal catheter and a 9 French 8 mm tip cryothermal catheter for cryoablation treatment of atrial flutter. Journal of Interventional Cardiac Electrophysiology, 13, 56–59.CrossRef Montenero, A. S., Bruno, N., Antonelli, A., Mangiameli, D., Barbieri, L., Andrew, P., et al. (2005). Comparison between a 7 French 6 mm tip cryothermal catheter and a 9 French 8 mm tip cryothermal catheter for cryoablation treatment of atrial flutter. Journal of Interventional Cardiac Electrophysiology, 13, 56–59.CrossRef
Metadaten
Titel
A prospective randomised comparison of large-tip cryoablation and 8-mm-tip radiofrequency catheter ablation of atrial flutter
verfasst von
Helena Malmborg
Stefan Lönnerholm
Carina Blomström Lundqvist
Publikationsdatum
01.03.2009
Verlag
Springer US
Erschienen in
Journal of Interventional Cardiac Electrophysiology / Ausgabe 2/2009
Print ISSN: 1383-875X
Elektronische ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-008-9315-1

Weitere Artikel der Ausgabe 2/2009

Journal of Interventional Cardiac Electrophysiology 2/2009 Zur Ausgabe

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

„Jeder Fall von plötzlichem Tod muss obduziert werden!“

17.05.2024 Plötzlicher Herztod Nachrichten

Ein signifikanter Anteil der Fälle von plötzlichem Herztod ist genetisch bedingt. Um ihre Verwandten vor diesem Schicksal zu bewahren, sollten jüngere Personen, die plötzlich unerwartet versterben, ausnahmslos einer Autopsie unterzogen werden.

Hirnblutung unter DOAK und VKA ähnlich bedrohlich

17.05.2024 Direkte orale Antikoagulanzien Nachrichten

Kommt es zu einer nichttraumatischen Hirnblutung, spielt es keine große Rolle, ob die Betroffenen zuvor direkt wirksame orale Antikoagulanzien oder Marcumar bekommen haben: Die Prognose ist ähnlich schlecht.

Schlechtere Vorhofflimmern-Prognose bei kleinem linken Ventrikel

17.05.2024 Vorhofflimmern Nachrichten

Nicht nur ein vergrößerter, sondern auch ein kleiner linker Ventrikel ist bei Vorhofflimmern mit einer erhöhten Komplikationsrate assoziiert. Der Zusammenhang besteht nach Daten aus China unabhängig von anderen Risikofaktoren.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.