Skip to main content
Erschienen in: AIDS and Behavior 9/2016

03.05.2016 | Original Paper

A Prospective Study of Intimate Partner Violence as a Risk Factor for Detectable Plasma Viral Load in HIV-Positive Women Engaged in Transactional Sex in Mombasa, Kenya

verfasst von: Kate S. Wilson, George Wanje, Krista Yuhas, Jane M. Simoni, Linnet Masese, Ann Vander Stoep, Walter Jaoko, James P. Hughes, Barbra A. Richardson, R. Scott McClelland

Erschienen in: AIDS and Behavior | Ausgabe 9/2016

Einloggen, um Zugang zu erhalten

Abstract

We conducted a prospective cohort study to evaluate intimate partner violence (IPV) as a risk factor for detectable plasma viral load in HIV-positive female sex workers (FSWs) on antiretroviral therapy (ART) in Kenya. IPV in the past year was defined as ≥1 act of physical, sexual, or emotional violence by the index partner (i.e. boyfriend/husband). The primary outcome was detectable viral load (≥180 copies/ml). In-depth interviews and focus groups were included to contextualize results. Analyses included 195 women (570 visits). Unexpectedly, IPV was associated with significantly lower risk of detectable viral load (adjusted relative risk 0.21, 95 % CI 0.05–0.84, p-value = 0.02). Qualitative findings revealed that women valued emotional and financial support from index partners, despite IPV. IPV was not a major barrier to ART adherence. The observed association between IPV and lower risk of detectable viral load in FSWs may be due to unmeasured personal and relationship factors, warranting further research.
Literatur
1.
Zurück zum Zitat Bangsberg DR, Perry S, Charlebois ED, Clark RA, Roberston M, Zolopa AR, et al. Non-adherence to highly active antiretroviral therapy predicts progression to AIDS. Aids. 2001;15(9):1181–3 (PubMed PMID: 11416722. Epub 2001/06/21. eng.).CrossRefPubMed Bangsberg DR, Perry S, Charlebois ED, Clark RA, Roberston M, Zolopa AR, et al. Non-adherence to highly active antiretroviral therapy predicts progression to AIDS. Aids. 2001;15(9):1181–3 (PubMed PMID: 11416722. Epub 2001/06/21. eng.).CrossRefPubMed
2.
Zurück zum Zitat Bangsberg DR, Acosta EP, Gupta R, Guzman D, Riley ED, Harrigan PR, et al. Adherence-resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitness. Aids. 2006;20(2):223–31.CrossRefPubMed Bangsberg DR, Acosta EP, Gupta R, Guzman D, Riley ED, Harrigan PR, et al. Adherence-resistance relationships for protease and non-nucleoside reverse transcriptase inhibitors explained by virological fitness. Aids. 2006;20(2):223–31.CrossRefPubMed
3.
Zurück zum Zitat Cohen M, Chen Y, McCauley M, Gamble T, Hosseinipour M, Kumarasami et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011;365(6):493–505. Cohen M, Chen Y, McCauley M, Gamble T, Hosseinipour M, Kumarasami et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011;365(6):493–505.
4.
Zurück zum Zitat Delva W, Eaton JW, Meng F, Fraser C, White RG, Vickerman P, et al. HIV treatment as prevention: optimising the impact of expanded HIV treatment programmes. PLoS Med. 2012;9(7):e1001258 (PubMed PMID: 22802738. Pubmed Central PMCID: 3393661. Epub 2012/07/18. eng.).CrossRefPubMedPubMedCentral Delva W, Eaton JW, Meng F, Fraser C, White RG, Vickerman P, et al. HIV treatment as prevention: optimising the impact of expanded HIV treatment programmes. PLoS Med. 2012;9(7):e1001258 (PubMed PMID: 22802738. Pubmed Central PMCID: 3393661. Epub 2012/07/18. eng.).CrossRefPubMedPubMedCentral
5.
Zurück zum Zitat UNAIDS. Access to antiretroviraltherapy in africa: status report on progress towards the 2015 targets. Geneva, Switzerland: UNAIDS, 2015. UNAIDS. Access to antiretroviraltherapy in africa: status report on progress towards the 2015 targets. Geneva, Switzerland: UNAIDS, 2015.
6.
Zurück zum Zitat Maman D, Zeh C, Mukui I, Kirubi B, Masson S, Opolo V, et al. Cascade of HIV care and population viral suppression in a high-burden region of Kenya. Aids. 2015;29(12):1557–65 (PubMed PMID: 26244395. Pubmed Central PMCID: 4502986).CrossRefPubMedPubMedCentral Maman D, Zeh C, Mukui I, Kirubi B, Masson S, Opolo V, et al. Cascade of HIV care and population viral suppression in a high-burden region of Kenya. Aids. 2015;29(12):1557–65 (PubMed PMID: 26244395. Pubmed Central PMCID: 4502986).CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Hardon AP, Akurut D, Comoro C, Ekezie C, Irunde HF, Gerrits T, et al. Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS Care. 2007;19(5):658–65 (PubMed PMID: 17505927. Epub 2007/05/17. eng.).CrossRefPubMed Hardon AP, Akurut D, Comoro C, Ekezie C, Irunde HF, Gerrits T, et al. Hunger, waiting time and transport costs: time to confront challenges to ART adherence in Africa. AIDS Care. 2007;19(5):658–65 (PubMed PMID: 17505927. Epub 2007/05/17. eng.).CrossRefPubMed
8.
Zurück zum Zitat Simbayi LC, Kalichman S, Strebel A, Cloete A, Henda N, Mqeketo A. Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa. Social Sci Med. 2007;64(9):1823–31 (PubMed PMID: 17337318. Epub 2007/03/06. eng.).CrossRef Simbayi LC, Kalichman S, Strebel A, Cloete A, Henda N, Mqeketo A. Internalized stigma, discrimination, and depression among men and women living with HIV/AIDS in Cape Town, South Africa. Social Sci Med. 2007;64(9):1823–31 (PubMed PMID: 17337318. Epub 2007/03/06. eng.).CrossRef
9.
Zurück zum Zitat Bajunirwe F, Tisch DJ, King CH, Arts EJ, Debanne SM, Sethi AK. Quality of life and social support among patients receiving antiretroviral therapy in Western Uganda. AIDS care. 2009 Mar;21(3):271-9. (PubMed PMID: 19280404. Epub 2009/03/13. eng). Bajunirwe F, Tisch DJ, King CH, Arts EJ, Debanne SM, Sethi AK. Quality of life and social support among patients receiving antiretroviral therapy in Western Uganda. AIDS care. 2009 Mar;21(3):271-9. (PubMed PMID: 19280404. Epub 2009/03/13. eng).
10.
Zurück zum Zitat Do NT, Phiri K, Bussmann H, Gaolathe T, Marlink RG, Wester CW. Psychosocial factors affecting medication adherence among HIV-1 infected adults receiving combination antiretroviral therapy (cART) in Botswana. AIDS Res Hum Retroviruses. 2010 Jun;26(6):685-91. (PubMed PMID: 20518649. Epub 2010/06/04. eng.) Do NT, Phiri K, Bussmann H, Gaolathe T, Marlink RG, Wester CW. Psychosocial factors affecting medication adherence among HIV-1 infected adults receiving combination antiretroviral therapy (cART) in Botswana. AIDS Res Hum Retroviruses. 2010 Jun;26(6):685-91. (PubMed PMID: 20518649. Epub 2010/06/04. eng.)
11.
Zurück zum Zitat Jaquet A, Ekouevi DK, Bashi J, Aboubakrine M, Messou E, Maiga M, et al. Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa. Addiction. 2010 Aug;105(8):1416-21. (PubMed PMID: 20528816. Epub 2010/06/10. eng). Jaquet A, Ekouevi DK, Bashi J, Aboubakrine M, Messou E, Maiga M, et al. Alcohol use and non-adherence to antiretroviral therapy in HIV-infected patients in West Africa. Addiction. 2010 Aug;105(8):1416-21. (PubMed PMID: 20528816. Epub 2010/06/10. eng).
12.
Zurück zum Zitat Devries KM, Mak JY, Garcia-Moreno C, Petzold M, Child JC, Falder G, et al. Global health. The global prevalence of intimate partner violence against women. Science. 2013 Jun 28;340(6140):1527-8. (PubMed PMID: 23788730. Epub 2013/06/22. eng). Devries KM, Mak JY, Garcia-Moreno C, Petzold M, Child JC, Falder G, et al. Global health. The global prevalence of intimate partner violence against women. Science. 2013 Jun 28;340(6140):1527-8. (PubMed PMID: 23788730. Epub 2013/06/22. eng).
13.
Zurück zum Zitat KNBS, NACC, NASCOP, NPHLS, KEMRI, NCAPD. Kenya Demographic and Health Survey 2008-09. Nairobi: 2009. KNBS, NACC, NASCOP, NPHLS, KEMRI, NCAPD. Kenya Demographic and Health Survey 2008-09. Nairobi: 2009.
14.
Zurück zum Zitat Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376(9734):41–8 (PubMed PMID: 20557928. Epub 2010/06/19. eng.).CrossRefPubMed Jewkes RK, Dunkle K, Nduna M, Shai N. Intimate partner violence, relationship power inequity, and incidence of HIV infection in young women in South Africa: a cohort study. Lancet. 2010;376(9734):41–8 (PubMed PMID: 20557928. Epub 2010/06/19. eng.).CrossRefPubMed
15.
Zurück zum Zitat Kouyoumdjian FG, Calzavara LM, Bondy SJ, O’Campo P, Serwadda D, Nalugoda F, et al. Intimate partner violence is associated with incident HIV infection in women in Uganda. Aids. 2013;27(8):1331–8 (PubMed PMID: 23925380. Epub 2013/08/09. eng.).CrossRefPubMed Kouyoumdjian FG, Calzavara LM, Bondy SJ, O’Campo P, Serwadda D, Nalugoda F, et al. Intimate partner violence is associated with incident HIV infection in women in Uganda. Aids. 2013;27(8):1331–8 (PubMed PMID: 23925380. Epub 2013/08/09. eng.).CrossRefPubMed
16.
Zurück zum Zitat Siemieniuk RA, Krentz HB, Miller P, Woodman K, Ko K, Gill MJ. The clinical implications of high rates of intimate partner violence against hiv-positive women. J Acquir Immune Defic Syndr. 2013;64(1):32–8 (PubMed PMID: 23714742. Epub 2013/05/30. eng.).CrossRefPubMed Siemieniuk RA, Krentz HB, Miller P, Woodman K, Ko K, Gill MJ. The clinical implications of high rates of intimate partner violence against hiv-positive women. J Acquir Immune Defic Syndr. 2013;64(1):32–8 (PubMed PMID: 23714742. Epub 2013/05/30. eng.).CrossRefPubMed
17.
Zurück zum Zitat Tsai AC, Wolfe WR, Kumbakumba E, Kawuma A, Hunt PW, Martin JN, et al. Prospective Study of the Mental Health Consequences of Sexual Violence Among Women Living With HIV in Rural Uganda. Journal of interpersonal violence. 2015 Jan 13. (PubMed PMID: 25586914. Epub 2015/01/15. Eng). Tsai AC, Wolfe WR, Kumbakumba E, Kawuma A, Hunt PW, Martin JN, et al. Prospective Study of the Mental Health Consequences of Sexual Violence Among Women Living With HIV in Rural Uganda. Journal of interpersonal violence. 2015 Jan 13. (PubMed PMID: 25586914. Epub 2015/01/15. Eng).
18.
Zurück zum Zitat Hatcher AM, Smout EM, Turan JM, Christofides N, Stockl H. Intimate partner violence and engagement in HIV care and treatment among women: a systematic review and meta-analysis. AIDS. 2015 Sep 5. (PubMed PMID: 26353027. Epub 2015/09/10. Eng). Hatcher AM, Smout EM, Turan JM, Christofides N, Stockl H. Intimate partner violence and engagement in HIV care and treatment among women: a systematic review and meta-analysis. AIDS. 2015 Sep 5. (PubMed PMID: 26353027. Epub 2015/09/10. Eng).
19.
Zurück zum Zitat Skovdal M, Campbell C, Nyamukapa C, Gregson S. When masculinity interferes with women’s treatment of HIV infection: a qualitative study about adherence to antiretroviral therapy in Zimbabwe. J Int AIDS Soc. 2011;14:29 (Pubmed Central PMCID: 3127801. Epub 2011/06/11. eng.).CrossRefPubMedPubMedCentral Skovdal M, Campbell C, Nyamukapa C, Gregson S. When masculinity interferes with women’s treatment of HIV infection: a qualitative study about adherence to antiretroviral therapy in Zimbabwe. J Int AIDS Soc. 2011;14:29 (Pubmed Central PMCID: 3127801. Epub 2011/06/11. eng.).CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Lichtenstein B. Domestic violence in barriers to health care for HIV-positive women. AIDS Patient Care STDS. 2006;20(2):122–32 (PubMed PMID: 16475893. Epub 2006/02/16. eng.).CrossRefPubMed Lichtenstein B. Domestic violence in barriers to health care for HIV-positive women. AIDS Patient Care STDS. 2006;20(2):122–32 (PubMed PMID: 16475893. Epub 2006/02/16. eng.).CrossRefPubMed
21.
Zurück zum Zitat Wechsberg WM, Luseno WK, Lam WK, Parry CD, Morojele NK. Substance use, sexual risk, and violence: HIV prevention intervention with sex workers in pretoria. AIDS Behav. 2006;10(2):131–7.CrossRefPubMed Wechsberg WM, Luseno WK, Lam WK, Parry CD, Morojele NK. Substance use, sexual risk, and violence: HIV prevention intervention with sex workers in pretoria. AIDS Behav. 2006;10(2):131–7.CrossRefPubMed
22.
Zurück zum Zitat Chersich MF, Luchters SM, Malonza IM, Mwarogo P, King’ola N, Temmerman M. Heavy episodic drinking among Kenyan female sex workers is associated with unsafe sex, sexual violence and sexually transmitted infections. Int J STD AIDS. 2007;18(11):764–9 (PubMed PMID: 18005511. Epub 2007/11/17. eng.).CrossRefPubMed Chersich MF, Luchters SM, Malonza IM, Mwarogo P, King’ola N, Temmerman M. Heavy episodic drinking among Kenyan female sex workers is associated with unsafe sex, sexual violence and sexually transmitted infections. Int J STD AIDS. 2007;18(11):764–9 (PubMed PMID: 18005511. Epub 2007/11/17. eng.).CrossRefPubMed
23.
Zurück zum Zitat Baral S, Beyrer C, Muessig K, Poteat T, Wirtz AL, Decker MR, et al. Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12(7):538–49 (PubMed PMID: 22424777. Epub 2012/03/20. eng.).CrossRefPubMed Baral S, Beyrer C, Muessig K, Poteat T, Wirtz AL, Decker MR, et al. Burden of HIV among female sex workers in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis. 2012;12(7):538–49 (PubMed PMID: 22424777. Epub 2012/03/20. eng.).CrossRefPubMed
24.
Zurück zum Zitat Odek WO, Githuka GN, Avery L, Njoroge PK, Kasonde L, Gorgens M, et al. Estimating the size of the female sex worker population in Kenya to inform HIV prevention programming. PLoS ONE. 2014;9(3):e89180 (PubMed PMID: 24595029. Pubmed Central PMCID: 3940432. Epub 2014/03/07. eng.).CrossRefPubMedPubMedCentral Odek WO, Githuka GN, Avery L, Njoroge PK, Kasonde L, Gorgens M, et al. Estimating the size of the female sex worker population in Kenya to inform HIV prevention programming. PLoS ONE. 2014;9(3):e89180 (PubMed PMID: 24595029. Pubmed Central PMCID: 3940432. Epub 2014/03/07. eng.).CrossRefPubMedPubMedCentral
25.
Zurück zum Zitat Gelmon L, Kenya HIV. Prevention response and modes of transmission analysis. Nairobi: Kenya National AIDS Control Council; 2009. Gelmon L, Kenya HIV. Prevention response and modes of transmission analysis. Nairobi: Kenya National AIDS Control Council; 2009.
26.
Zurück zum Zitat Voeten HA, Egesah OB, Varkevisser CM, Habbema JD. Female sex workers and unsafe sex in urban and rural Nyanza, Kenya: regular partners may contribute more to HIV transmission than clients. Trop Med Int Health TM IH. 2007;12(2):174–82 (PubMed PMID: 17300623. Epub 2007/02/16. eng.).PubMed Voeten HA, Egesah OB, Varkevisser CM, Habbema JD. Female sex workers and unsafe sex in urban and rural Nyanza, Kenya: regular partners may contribute more to HIV transmission than clients. Trop Med Int Health TM IH. 2007;12(2):174–82 (PubMed PMID: 17300623. Epub 2007/02/16. eng.).PubMed
27.
Zurück zum Zitat Pack AP, L’Engle K, Mwarogo P, Kingola N. Intimate partner violence against female sex workers in Mombasa, Kenya. Culture, health & sexuality. 2013 Dec 11. (PubMed PMID: 24329103. Epub 2013/12/18. Eng). Pack AP, L’Engle K, Mwarogo P, Kingola N. Intimate partner violence against female sex workers in Mombasa, Kenya. Culture, health & sexuality. 2013 Dec 11. (PubMed PMID: 24329103. Epub 2013/12/18. Eng).
28.
Zurück zum Zitat Wilson KS, Deya R, Masese L, Simoni JM, Vander Stoep A, Shafi J, et al. Prevalence and correlates of intimate partner violence in HIV-positive women engaged in transactional sex in Mombasa, Kenya. International journal of STD & AIDS. 2015 Oct 12. (PubMed PMID: 26464502). Wilson KS, Deya R, Masese L, Simoni JM, Vander Stoep A, Shafi J, et al. Prevalence and correlates of intimate partner violence in HIV-positive women engaged in transactional sex in Mombasa, Kenya. International journal of STD & AIDS. 2015 Oct 12. (PubMed PMID: 26464502).
29.
Zurück zum Zitat Wechsberg WM, Luseno WK, Kline TL, Browne FA, Zule WA. Preliminary findings of an adapted evidence-based woman-focused HIV intervention on condom use and negotiation among at-risk women in Pretoria, South Africa. J Prev Interv Commun. 2010;38(2):132–46 (PubMed PMID: 20391060. Pubmed Central PMCID: 3129984. Epub 2010/04/15. eng.).CrossRef Wechsberg WM, Luseno WK, Kline TL, Browne FA, Zule WA. Preliminary findings of an adapted evidence-based woman-focused HIV intervention on condom use and negotiation among at-risk women in Pretoria, South Africa. J Prev Interv Commun. 2010;38(2):132–46 (PubMed PMID: 20391060. Pubmed Central PMCID: 3129984. Epub 2010/04/15. eng.).CrossRef
30.
Zurück zum Zitat Jones D, Kashy D, Chitalu N, Kankasa C, Mumbi M, Cook R, et al. Risk reduction among HIV-seroconcordant and -discordant couples: the Zambia NOW2 intervention. AIDS Patient Care STDs. 2014;28(8):433–41 (PubMed PMID: 24983201. Pubmed Central PMCID: 4117267).CrossRefPubMedPubMedCentral Jones D, Kashy D, Chitalu N, Kankasa C, Mumbi M, Cook R, et al. Risk reduction among HIV-seroconcordant and -discordant couples: the Zambia NOW2 intervention. AIDS Patient Care STDs. 2014;28(8):433–41 (PubMed PMID: 24983201. Pubmed Central PMCID: 4117267).CrossRefPubMedPubMedCentral
31.
Zurück zum Zitat Abramsky T, Devries KM, Michau L, Nakuti J, Musuya T, Kyegombe N, et al. The impact of SASA!, a community mobilisation intervention, on women’s experiences of intimate partner violence: secondary findings from a cluster randomised trial in Kampala, Uganda. Journal of epidemiology and community health. 2016 Feb 12. (PubMed PMID: 26873948). Abramsky T, Devries KM, Michau L, Nakuti J, Musuya T, Kyegombe N, et al. The impact of SASA!, a community mobilisation intervention, on women’s experiences of intimate partner violence: secondary findings from a cluster randomised trial in Kampala, Uganda. Journal of epidemiology and community health. 2016 Feb 12. (PubMed PMID: 26873948).
32.
Zurück zum Zitat Decker MR, Wirtz AL, Pretorius C, Sherman SG, Sweat MD, Baral SD, et al. Estimating the impact of reducing violence against female sex workers on HIV epidemics in Kenya and Ukraine: a policy modeling exercise. Am J Reprod Immunol. 2013;69(Suppl 1):122–32.CrossRefPubMed Decker MR, Wirtz AL, Pretorius C, Sherman SG, Sweat MD, Baral SD, et al. Estimating the impact of reducing violence against female sex workers on HIV epidemics in Kenya and Ukraine: a policy modeling exercise. Am J Reprod Immunol. 2013;69(Suppl 1):122–32.CrossRefPubMed
33.
Zurück zum Zitat Kenya_Ministry_of_Health. Kenya_HIV_Prevention_Revolution_Road_Map. Nairobi, Kenya: Ministry of Health, 2014. Kenya_Ministry_of_Health. Kenya_HIV_Prevention_Revolution_Road_Map. Nairobi, Kenya: Ministry of Health, 2014.
34.
Zurück zum Zitat Ellsberg M, Heise L. Researching violence against women: a practical guide for researchers and activists. Washington DC: World Health Organization, PATH; 2005. Ellsberg M, Heise L. Researching violence against women: a practical guide for researchers and activists. Washington DC: World Health Organization, PATH; 2005.
35.
Zurück zum Zitat Graham SM, Jalalian-Lechak Z, Shafi J, Chohan V, Deya RW, Jaoko W, et al. Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA. J Acquir Immune Defic Syndr. 2012;60(5):511–8 (PubMed PMID: 22592588. Pubmed Central PMCID: 3404237. Epub 2012/05/18. eng.).CrossRefPubMedPubMedCentral Graham SM, Jalalian-Lechak Z, Shafi J, Chohan V, Deya RW, Jaoko W, et al. Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA. J Acquir Immune Defic Syndr. 2012;60(5):511–8 (PubMed PMID: 22592588. Pubmed Central PMCID: 3404237. Epub 2012/05/18. eng.).CrossRefPubMedPubMedCentral
36.
Zurück zum Zitat Graham SM, Masese L, Gitau R, Jalalian-Lechak Z, Richardson BA, Peshu N, et al. Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV shedding among women initiating treatment. J Infect Dis. 2010;202:1538–42.CrossRefPubMedPubMedCentral Graham SM, Masese L, Gitau R, Jalalian-Lechak Z, Richardson BA, Peshu N, et al. Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV shedding among women initiating treatment. J Infect Dis. 2010;202:1538–42.CrossRefPubMedPubMedCentral
37.
Zurück zum Zitat Lu M, Safren SA, Skolnik PR, Rogers WH, Coady W, Hardy H, et al. Optimal recall period and response task for self-reported HIV medication adherence. AIDS Behav. 2008;12(1):86–94 (PubMed PMID: 17577653. Epub 2007/06/20. eng.).CrossRefPubMed Lu M, Safren SA, Skolnik PR, Rogers WH, Coady W, Hardy H, et al. Optimal recall period and response task for self-reported HIV medication adherence. AIDS Behav. 2008;12(1):86–94 (PubMed PMID: 17577653. Epub 2007/06/20. eng.).CrossRefPubMed
38.
Zurück zum Zitat Garcia-Moreno C, Jansen HA, Ellsberg M, Heise L, Watts CH. Prevalence of intimate partner violence: findings from the WHO multi-country study on women’s health and domestic violence. Lancet. 2006;368(9543):1260–9.CrossRefPubMed Garcia-Moreno C, Jansen HA, Ellsberg M, Heise L, Watts CH. Prevalence of intimate partner violence: findings from the WHO multi-country study on women’s health and domestic violence. Lancet. 2006;368(9543):1260–9.CrossRefPubMed
39.
Zurück zum Zitat Schraiber LB, Latorre Mdo R, Franca I, Jr., Segri NJ, D’Oliveira AF. Validity of the WHO VAW study instrument for estimating gender-based violence against women. Revista de saude publica. 2010;44(4):658–66. (PubMed PMID: 20676557. Epub 2010/08/03. eng). Schraiber LB, Latorre Mdo R, Franca I, Jr., Segri NJ, D’Oliveira AF. Validity of the WHO VAW study instrument for estimating gender-based violence against women. Revista de saude publica. 2010;44(4):658–66. (PubMed PMID: 20676557. Epub 2010/08/03. eng).
40.
Zurück zum Zitat World_Health_Organization. WHO Multi-Country Study on Women’s Health and Domestic Violence: core questionnaire and WHO instrument, version 9. 9 ed. Geneva, Switzerland: WHO; 2000. World_Health_Organization. WHO Multi-Country Study on Women’s Health and Domestic Violence: core questionnaire and WHO instrument, version 9. 9 ed. Geneva, Switzerland: WHO; 2000.
41.
Zurück zum Zitat Omoro SA, Fann JR, Weymuller EA, Macharia IM, Yueh B. Swahili translation and validation of the Patient Health Questionnaire-9 depression scale in the Kenyan head and neck cancer patient population. Int J Psychiatry Med. 2006;36(3):367–81 (PubMed PMID: 17236703. Epub 2007/01/24. eng.).CrossRefPubMed Omoro SA, Fann JR, Weymuller EA, Macharia IM, Yueh B. Swahili translation and validation of the Patient Health Questionnaire-9 depression scale in the Kenyan head and neck cancer patient population. Int J Psychiatry Med. 2006;36(3):367–81 (PubMed PMID: 17236703. Epub 2007/01/24. eng.).CrossRefPubMed
42.
Zurück zum Zitat Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption–II. Addiction. 1993;88(6):791–804 (PubMed PMID: 8329970. Epub 1993/06/01. eng.).CrossRefPubMed Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M. Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption–II. Addiction. 1993;88(6):791–804 (PubMed PMID: 8329970. Epub 1993/06/01. eng.).CrossRefPubMed
43.
Zurück zum Zitat Peltzer K, Chao LW, Dana P. Family planning among HIV positive and negative prevention of mother to child transmission (PMTCT) clients in a resource poor setting in South Africa. AIDS Behav. 2009;13(5):973–9 (PubMed PMID: 18286365. Epub 2008/02/21. eng.).CrossRefPubMed Peltzer K, Chao LW, Dana P. Family planning among HIV positive and negative prevention of mother to child transmission (PMTCT) clients in a resource poor setting in South Africa. AIDS Behav. 2009;13(5):973–9 (PubMed PMID: 18286365. Epub 2008/02/21. eng.).CrossRefPubMed
44.
Zurück zum Zitat Bonomi AE, Thompson RS, Anderson M, Reid RJ, Carrell D, Dimer JA, et al. Intimate partner violence and women’s physical, mental, and social functioning. Am J Prev Med. 2006;30(6):458–66 (PubMed PMID: 16704938. Epub 2006/05/18. eng.).CrossRefPubMed Bonomi AE, Thompson RS, Anderson M, Reid RJ, Carrell D, Dimer JA, et al. Intimate partner violence and women’s physical, mental, and social functioning. Am J Prev Med. 2006;30(6):458–66 (PubMed PMID: 16704938. Epub 2006/05/18. eng.).CrossRefPubMed
45.
Zurück zum Zitat Thompson RS, Bonomi AE, Anderson M, Reid RJ, Dimer JA, Carrell D, et al. Intimate partner violence: prevalence, types, and chronicity in adult women. Am J Prev Med. 2006;30(6):447–57 (PubMed PMID: 16704937. Epub 2006/05/18. eng.).CrossRefPubMed Thompson RS, Bonomi AE, Anderson M, Reid RJ, Dimer JA, Carrell D, et al. Intimate partner violence: prevalence, types, and chronicity in adult women. Am J Prev Med. 2006;30(6):447–57 (PubMed PMID: 16704937. Epub 2006/05/18. eng.).CrossRefPubMed
46.
Zurück zum Zitat Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42(1):121–30.CrossRefPubMed Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42(1):121–30.CrossRefPubMed
47.
Zurück zum Zitat Cohen MH, Cook JA, Grey D, Young M, Hanau LH, Tien P, et al. Medically eligible women who do not use HAART: the importance of abuse, drug use, and race. Am J Publ Health. 2004;94(7):1147–51 (PubMed PMID: 15226135. Pubmed Central PMCID: 1448413).CrossRef Cohen MH, Cook JA, Grey D, Young M, Hanau LH, Tien P, et al. Medically eligible women who do not use HAART: the importance of abuse, drug use, and race. Am J Publ Health. 2004;94(7):1147–51 (PubMed PMID: 15226135. Pubmed Central PMCID: 1448413).CrossRef
48.
Zurück zum Zitat Dale SK, Weber KM, Cohen MH, Kelso GA, Cruise RC, Brody LR. Resilience Moderates the Association Between Childhood Sexual Abuse and Depressive Symptoms Among Women with and At-Risk for HIV. AIDS Behav. 2014 Aug 2. (PubMed PMID: 25085079. Pubmed Central PMCID: 4314513. Epub 2014/08/03. Eng.) Dale SK, Weber KM, Cohen MH, Kelso GA, Cruise RC, Brody LR. Resilience Moderates the Association Between Childhood Sexual Abuse and Depressive Symptoms Among Women with and At-Risk for HIV. AIDS Behav. 2014 Aug 2. (PubMed PMID: 25085079. Pubmed Central PMCID: 4314513. Epub 2014/08/03. Eng.)
49.
Zurück zum Zitat Glass TR, De Geest S, Weber R, Vernazza PL, Rickenbach M, Furrer H, et al. Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study. J Acquir Immune Defic Syndr. 2006;41(3):385–92.CrossRefPubMed Glass TR, De Geest S, Weber R, Vernazza PL, Rickenbach M, Furrer H, et al. Correlates of self-reported nonadherence to antiretroviral therapy in HIV-infected patients: the Swiss HIV Cohort Study. J Acquir Immune Defic Syndr. 2006;41(3):385–92.CrossRefPubMed
50.
Zurück zum Zitat Espino SR, Fletcher J, Gonzalez M, Precht A, Xavier J, Matoff-Stepp S. Violence screening and viral load suppression among HIV-positive women of color. AIDS Patient Care STDS. 2015 Jan;29 Suppl 1:S36-41. (PubMed PMID: 25561308. Pubmed Central PMCID: 4283058. Epub 2015/01/07. eng). Espino SR, Fletcher J, Gonzalez M, Precht A, Xavier J, Matoff-Stepp S. Violence screening and viral load suppression among HIV-positive women of color. AIDS Patient Care STDS. 2015 Jan;29 Suppl 1:S36-41. (PubMed PMID: 25561308. Pubmed Central PMCID: 4283058. Epub 2015/01/07. eng).
51.
Zurück zum Zitat Schafer KR, Brant J, Gupta S, Thorpe J, Winstead-Derlega C, Pinkerton R, et al. Intimate partner violence: a predictor of worse HIV outcomes and engagement in care. AIDS Patient Care STDs. 2012;26(6):356–65 (PubMed PMID: 22612519. Pubmed Central PMCID: 3366337).CrossRefPubMedPubMedCentral Schafer KR, Brant J, Gupta S, Thorpe J, Winstead-Derlega C, Pinkerton R, et al. Intimate partner violence: a predictor of worse HIV outcomes and engagement in care. AIDS Patient Care STDs. 2012;26(6):356–65 (PubMed PMID: 22612519. Pubmed Central PMCID: 3366337).CrossRefPubMedPubMedCentral
52.
Zurück zum Zitat Sullivan KA, Messer LC, Quinlivan EB. Substance abuse, violence, and HIV/AIDS (SAVA) syndemic effects on viral suppression among HIV positive women of color. AIDS Patient Care STDS. 2015;29 Suppl 1:S42–8. (PubMed PMID: 25397666. Pubmed Central PMCID: 4283071. Epub 2014/11/15. eng). Sullivan KA, Messer LC, Quinlivan EB. Substance abuse, violence, and HIV/AIDS (SAVA) syndemic effects on viral suppression among HIV positive women of color. AIDS Patient Care STDS. 2015;29 Suppl 1:S42–8. (PubMed PMID: 25397666. Pubmed Central PMCID: 4283071. Epub 2014/11/15. eng).
53.
Zurück zum Zitat Mugavero M, Ostermann J, Whetten K, Leserman J, Swartz M, Stangl D, et al. Barriers to antiretroviral adherence: the importance of depression, abuse, and other traumatic events. AIDS Patient Care STDs. 2006;20(6):418–28.CrossRef Mugavero M, Ostermann J, Whetten K, Leserman J, Swartz M, Stangl D, et al. Barriers to antiretroviral adherence: the importance of depression, abuse, and other traumatic events. AIDS Patient Care STDs. 2006;20(6):418–28.CrossRef
54.
Zurück zum Zitat Sikkema KJ, Watt MH, Drabkin AS, Meade CS, Hansen NB, Pence BW. Mental health treatment to reduce HIV transmission risk behavior: a positive prevention model. AIDS Behav. 2010;14(2):252–62 (PubMed PMID: 20013043. Pubmed Central PMCID: 2835810).CrossRefPubMedPubMedCentral Sikkema KJ, Watt MH, Drabkin AS, Meade CS, Hansen NB, Pence BW. Mental health treatment to reduce HIV transmission risk behavior: a positive prevention model. AIDS Behav. 2010;14(2):252–62 (PubMed PMID: 20013043. Pubmed Central PMCID: 2835810).CrossRefPubMedPubMedCentral
55.
Zurück zum Zitat Machtinger EL, Haberer JE, Wilson TC, Weiss DS. Recent trauma is associated with antiretroviral failure and HIV transmission risk behavior among HIV-positive women and female-identified transgenders. AIDS Behav. 2012;16(8):2160–70.CrossRefPubMed Machtinger EL, Haberer JE, Wilson TC, Weiss DS. Recent trauma is associated with antiretroviral failure and HIV transmission risk behavior among HIV-positive women and female-identified transgenders. AIDS Behav. 2012;16(8):2160–70.CrossRefPubMed
56.
Zurück zum Zitat Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol. 19931;138(11):923–36. (PubMed PMID: 8256780. Epub 1993/12/01. eng). Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol. 19931;138(11):923–36. (PubMed PMID: 8256780. Epub 1993/12/01. eng).
57.
Zurück zum Zitat Abramsky T, Watts CH, Garcia-Moreno C, Devries K, Kiss L, Ellsberg M, et al. What factors are associated with recent intimate partner violence? findings from the WHO multi-country study on women’s health and domestic violence. BMC Publ Health. 2011;11:109 (PubMed PMID: 21324186. Pubmed Central PMCID: 3049145).CrossRef Abramsky T, Watts CH, Garcia-Moreno C, Devries K, Kiss L, Ellsberg M, et al. What factors are associated with recent intimate partner violence? findings from the WHO multi-country study on women’s health and domestic violence. BMC Publ Health. 2011;11:109 (PubMed PMID: 21324186. Pubmed Central PMCID: 3049145).CrossRef
58.
Zurück zum Zitat Chi BH, Yiannoutsos CT, Westfall AO, Newman JE, Zhou J, Cesar C, et al. Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America. PLoS Med. 2011;8(10):e1001111 (PubMed PMID: 22039357. Pubmed Central PMCID: 3201937. Epub 2011/11/01. eng.).CrossRefPubMedPubMedCentral Chi BH, Yiannoutsos CT, Westfall AO, Newman JE, Zhou J, Cesar C, et al. Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America. PLoS Med. 2011;8(10):e1001111 (PubMed PMID: 22039357. Pubmed Central PMCID: 3201937. Epub 2011/11/01. eng.).CrossRefPubMedPubMedCentral
59.
Zurück zum Zitat Sankar A, Golin C, Simoni JM, Luborsky M, Pearson C. How qualitative methods contribute to understanding combination antiretroviral therapy adherence. Journal of acquired immune deficiency syndromes. 2006;1;43 Suppl 1:S54-68. (PubMed PMID: 17133205. Epub 2006/11/30. eng). Sankar A, Golin C, Simoni JM, Luborsky M, Pearson C. How qualitative methods contribute to understanding combination antiretroviral therapy adherence. Journal of acquired immune deficiency syndromes. 2006;1;43 Suppl 1:S54-68. (PubMed PMID: 17133205. Epub 2006/11/30. eng).
60.
Zurück zum Zitat Heise LL. Violence against women: an integrated, ecological framework. Violence Against Women. 1998;4(3):262–90.CrossRefPubMed Heise LL. Violence against women: an integrated, ecological framework. Violence Against Women. 1998;4(3):262–90.CrossRefPubMed
61.
Zurück zum Zitat Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. International journal for quality in health care : journal of the International Society for Quality in Health Care/ISQua. 2007 Dec;19(6):349-57. (PubMed PMID: 17872937. Epub 2007/09/18. eng). Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. International journal for quality in health care : journal of the International Society for Quality in Health Care/ISQua. 2007 Dec;19(6):349-57. (PubMed PMID: 17872937. Epub 2007/09/18. eng).
62.
Zurück zum Zitat Illangasekare S, Tello M, Hutton H, Moore R, Anderson J, Baron J, et al. Clinical and mental health correlates and risk factors for intimate partner violence among HIV-positive women in an inner-city HIV clinic. Women’s Health Issues Off Publ Jacobs Inst Women’s Health. 2012;22(6):e563–9 (PubMed PMID: 22939089. Pubmed Central PMCID: 3489982. Epub 2012/09/04. eng.).CrossRef Illangasekare S, Tello M, Hutton H, Moore R, Anderson J, Baron J, et al. Clinical and mental health correlates and risk factors for intimate partner violence among HIV-positive women in an inner-city HIV clinic. Women’s Health Issues Off Publ Jacobs Inst Women’s Health. 2012;22(6):e563–9 (PubMed PMID: 22939089. Pubmed Central PMCID: 3489982. Epub 2012/09/04. eng.).CrossRef
63.
Zurück zum Zitat Trimble DD, Nava A, McFarlane J. Intimate partner violence and antiretroviral adherence among women receiving care in an urban Southeastern Texas HIV clinic. J Assoc Nurses AIDS Care. 2013;24(4):331–40 (PubMed PMID: 23790276. Epub 2013/06/26. eng.).CrossRefPubMed Trimble DD, Nava A, McFarlane J. Intimate partner violence and antiretroviral adherence among women receiving care in an urban Southeastern Texas HIV clinic. J Assoc Nurses AIDS Care. 2013;24(4):331–40 (PubMed PMID: 23790276. Epub 2013/06/26. eng.).CrossRefPubMed
64.
Zurück zum Zitat Wirtz AL, Pretorius C, Beyrer C, Baral S, Decker MR, Sherman SG, et al. Epidemic impacts of a community empowerment intervention for HIV prevention among female sex workers in generalized and concentrated epidemics. PLoS ONE. 2014;9(2):e88047 (PubMed PMID: 24516580. Pubmed Central PMCID: 3916392).CrossRefPubMedPubMedCentral Wirtz AL, Pretorius C, Beyrer C, Baral S, Decker MR, Sherman SG, et al. Epidemic impacts of a community empowerment intervention for HIV prevention among female sex workers in generalized and concentrated epidemics. PLoS ONE. 2014;9(2):e88047 (PubMed PMID: 24516580. Pubmed Central PMCID: 3916392).CrossRefPubMedPubMedCentral
65.
Zurück zum Zitat Huet C, Ouedraogo A, Konate I, Traore I, Rouet F, Kabore A, et al. Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa. BMC Publ Health. 2011;11:700 (PubMed PMID: 21917177. Pubmed Central PMCID: 3191514).CrossRef Huet C, Ouedraogo A, Konate I, Traore I, Rouet F, Kabore A, et al. Long-term virological, immunological and mortality outcomes in a cohort of HIV-infected female sex workers treated with highly active antiretroviral therapy in Africa. BMC Publ Health. 2011;11:700 (PubMed PMID: 21917177. Pubmed Central PMCID: 3191514).CrossRef
66.
Zurück zum Zitat Lopez EJ, Jones DL, Villar-Loubet OM, Arheart KL, Weiss SM. Violence, coping, and consistent medication adherence in HIV-positive couples. AIDS Educ Prev. 2010;22(1):61–8 (PubMed PMID: 20166788. Epub 2010/02/20. eng.).CrossRefPubMedPubMedCentral Lopez EJ, Jones DL, Villar-Loubet OM, Arheart KL, Weiss SM. Violence, coping, and consistent medication adherence in HIV-positive couples. AIDS Educ Prev. 2010;22(1):61–8 (PubMed PMID: 20166788. Epub 2010/02/20. eng.).CrossRefPubMedPubMedCentral
67.
Zurück zum Zitat Hatcher AM, Romito P, Odero M, Bukusi EA, Onono M, Turan JM. Social context and drivers of intimate partner violence in rural Kenya: implications for the health of pregnant women. Cult Health Sex. 2013;15(4):404–19 (PubMed PMID: 23387300. Pubmed Central PMCID: 3808173. Epub 2013/02/08. eng.).CrossRefPubMed Hatcher AM, Romito P, Odero M, Bukusi EA, Onono M, Turan JM. Social context and drivers of intimate partner violence in rural Kenya: implications for the health of pregnant women. Cult Health Sex. 2013;15(4):404–19 (PubMed PMID: 23387300. Pubmed Central PMCID: 3808173. Epub 2013/02/08. eng.).CrossRefPubMed
68.
Zurück zum Zitat Wathen CN, MacGregor JC, Hammerton J, Coben JH, Herrman H, Stewart DE, et al. Priorities for research in child maltreatment, intimate partner violence and resilience to violence exposures: results of an international Delphi consensus development process. BMC Public Health. 2012;12:684 (PubMed PMID: 22908894. Pubmed Central PMCID: 3490760. Epub 2012/08/23. eng.).CrossRefPubMedPubMedCentral Wathen CN, MacGregor JC, Hammerton J, Coben JH, Herrman H, Stewart DE, et al. Priorities for research in child maltreatment, intimate partner violence and resilience to violence exposures: results of an international Delphi consensus development process. BMC Public Health. 2012;12:684 (PubMed PMID: 22908894. Pubmed Central PMCID: 3490760. Epub 2012/08/23. eng.).CrossRefPubMedPubMedCentral
69.
Zurück zum Zitat Benoit C, Roth E, Hallgrimsdottir H, Jansson M, Ngugi E, Sharpe K. Benefits and constraints of intimate partnerships for HIV positive sex workers in Kibera, Kenya. Int J Equity Health. 2013;12:76 (PubMed PMID: 24006868. Pubmed Central PMCID: 3766681. Epub 2013/09/07. eng.).CrossRefPubMedPubMedCentral Benoit C, Roth E, Hallgrimsdottir H, Jansson M, Ngugi E, Sharpe K. Benefits and constraints of intimate partnerships for HIV positive sex workers in Kibera, Kenya. Int J Equity Health. 2013;12:76 (PubMed PMID: 24006868. Pubmed Central PMCID: 3766681. Epub 2013/09/07. eng.).CrossRefPubMedPubMedCentral
70.
Zurück zum Zitat Schiff M, Gilbert L, El-Bassel N. Perceived positive aspects of intimate relationships among abused women in methadone maintenance treatment programs (MMTP). J Interpers Violence. 2006;21(1):121–38 (PubMed PMID: 16399927. Epub 2006/01/10. eng.).CrossRefPubMed Schiff M, Gilbert L, El-Bassel N. Perceived positive aspects of intimate relationships among abused women in methadone maintenance treatment programs (MMTP). J Interpers Violence. 2006;21(1):121–38 (PubMed PMID: 16399927. Epub 2006/01/10. eng.).CrossRefPubMed
71.
Zurück zum Zitat Jewkes R. (How) can we reduce violence against women by 50% over the next 30 years? PLoS Med. 2014;11(11):e1001761 (PubMed PMID: 25423110. Pubmed Central PMCID: 4244032. Epub 2014/11/26. eng.).CrossRefPubMedPubMedCentral Jewkes R. (How) can we reduce violence against women by 50% over the next 30 years? PLoS Med. 2014;11(11):e1001761 (PubMed PMID: 25423110. Pubmed Central PMCID: 4244032. Epub 2014/11/26. eng.).CrossRefPubMedPubMedCentral
Metadaten
Titel
A Prospective Study of Intimate Partner Violence as a Risk Factor for Detectable Plasma Viral Load in HIV-Positive Women Engaged in Transactional Sex in Mombasa, Kenya
verfasst von
Kate S. Wilson
George Wanje
Krista Yuhas
Jane M. Simoni
Linnet Masese
Ann Vander Stoep
Walter Jaoko
James P. Hughes
Barbra A. Richardson
R. Scott McClelland
Publikationsdatum
03.05.2016
Verlag
Springer US
Erschienen in
AIDS and Behavior / Ausgabe 9/2016
Print ISSN: 1090-7165
Elektronische ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-016-1420-z

Weitere Artikel der Ausgabe 9/2016

AIDS and Behavior 9/2016 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Echinokokkose medikamentös behandeln oder operieren?

06.05.2024 DCK 2024 Kongressbericht

Die Therapie von Echinokokkosen sollte immer in spezialisierten Zentren erfolgen. Eine symptomlose Echinokokkose kann – egal ob von Hunde- oder Fuchsbandwurm ausgelöst – konservativ erfolgen. Wenn eine Op. nötig ist, kann es sinnvoll sein, vorher Zysten zu leeren und zu desinfizieren. 

Umsetzung der POMGAT-Leitlinie läuft

03.05.2024 DCK 2024 Kongressbericht

Seit November 2023 gibt es evidenzbasierte Empfehlungen zum perioperativen Management bei gastrointestinalen Tumoren (POMGAT) auf S3-Niveau. Vieles wird schon entsprechend der Empfehlungen durchgeführt. Wo es im Alltag noch hapert, zeigt eine Umfrage in einem Klinikverbund.

Proximale Humerusfraktur: Auch 100-Jährige operieren?

01.05.2024 DCK 2024 Kongressbericht

Mit dem demographischen Wandel versorgt auch die Chirurgie immer mehr betagte Menschen. Von Entwicklungen wie Fast-Track können auch ältere Menschen profitieren und bei proximaler Humerusfraktur können selbst manche 100-Jährige noch sicher operiert werden.

Die „Zehn Gebote“ des Endokarditis-Managements

30.04.2024 Endokarditis Leitlinie kompakt

Worauf kommt es beim Management von Personen mit infektiöser Endokarditis an? Eine Kardiologin und ein Kardiologe fassen die zehn wichtigsten Punkte der neuen ESC-Leitlinie zusammen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.