Skip to main content
Erschienen in: Indian Journal of Pediatrics 12/2012

01.12.2012 | Original Article

A Survey of Procedural Sedation and Analgesia Practices in Pediatric Oncology Centers in India

verfasst von: Ramandeep Singh Arora, Ketan P. Kulkarni, Robert D. Alston

Erschienen in: Indian Journal of Pediatrics | Ausgabe 12/2012

Einloggen, um Zugang zu erhalten

Abstract

Objective

Repeated lumbar punctures (LP) and bone marrow aspirations (BMA) are part of childhood cancer management. Adequate sedation and analgesia for these procedures in a safe environment is desirable. We evaluate current practice related to this in pediatric oncology centers in India.

Methods

Clinicians attending the 2nd Annual India Pediatric Oncology Initiative meeting at New Delhi in February 2010 were invited to complete a questionnaire. Questionnaires were also sent by email to the remaining major pediatric oncology centers not represented at the meeting. Responses for LP and BMA were separately collated and variability by type of hospital and patient caseload was assessed.

Results

Responses were obtained from 26 of 32 centers (81%) approached. A median of 3 personnel (mostly pediatric residents and nurses) were present during the procedures. Some form of sedation and analgesia was used for LP and BMA in 88.5% and 100% centers respectively. However, use of systemic sedation and analgesia (usually midazolam +/− ketamine) for LP and BMA in ≥75% patients was seen in 47.8% and 61.6% centers respectively. General anesthesia was not used in any center. Additional restraint was commonly used and its use was significantly more in public hospitals (p = 0.01). Monitoring was usually done by observation of vital signs, with use of pulse-oximetry in less than half of the centers.

Conclusions

There is varied use of sedation and analgesia for LP and BMA in pediatric oncology centers in India. Further research is needed to identify the reasons for this. Availability of resources is likely to be a factor.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Ljungman G, Gordh T, Sörensen S, Kreuger A. Pain in paediatric oncology: interviews with children, adolescents and their parents. Acta Paediatr. 1999;88:623–30.PubMedCrossRef Ljungman G, Gordh T, Sörensen S, Kreuger A. Pain in paediatric oncology: interviews with children, adolescents and their parents. Acta Paediatr. 1999;88:623–30.PubMedCrossRef
2.
Zurück zum Zitat Ljungman G, Kreuger A, Gordh T, Berg T, Sörensen S, Rawal N. Treatment of pain in pediatric oncology: a Swedish nationwide survey. Pain. 1996;68:385–94.PubMedCrossRef Ljungman G, Kreuger A, Gordh T, Berg T, Sörensen S, Rawal N. Treatment of pain in pediatric oncology: a Swedish nationwide survey. Pain. 1996;68:385–94.PubMedCrossRef
3.
Zurück zum Zitat Howard SC, Gajjar AJ, Cheng C, et al. Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia. JAMA. 2002;288:2001–7.PubMedCrossRef Howard SC, Gajjar AJ, Cheng C, et al. Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia. JAMA. 2002;288:2001–7.PubMedCrossRef
4.
Zurück zum Zitat Gajjar A, Harrison PL, Sandlund JT, et al. Traumatic lumbar puncture at diagnosis adversely affects outcome in childhood acute lymphoblastic leukemia. Blood. 2000;96:3381–4.PubMed Gajjar A, Harrison PL, Sandlund JT, et al. Traumatic lumbar puncture at diagnosis adversely affects outcome in childhood acute lymphoblastic leukemia. Blood. 2000;96:3381–4.PubMed
5.
Zurück zum Zitat Bürger B, Zimmermann M, Mann G, et al. Diagnostic cerebrospinal fluid examination in children with acute lymphoblastic leukemia: significance of low leukocyte counts with blasts or traumatic lumbar puncture. J Clin Oncol. 2003;21:184–8.PubMedCrossRef Bürger B, Zimmermann M, Mann G, et al. Diagnostic cerebrospinal fluid examination in children with acute lymphoblastic leukemia: significance of low leukocyte counts with blasts or traumatic lumbar puncture. J Clin Oncol. 2003;21:184–8.PubMedCrossRef
6.
Zurück zum Zitat Krauss B, Green SM. Procedural sedation and analgesia in children. Lancet. 2006;367:766–80.PubMedCrossRef Krauss B, Green SM. Procedural sedation and analgesia in children. Lancet. 2006;367:766–80.PubMedCrossRef
7.
Zurück zum Zitat Hockenberry MJ, McCarthy K, Taylor O, et al. Managing painful procedures in children with cancer. J Pediatr Hematol Oncol. 2011;33:119–27.PubMedCrossRef Hockenberry MJ, McCarthy K, Taylor O, et al. Managing painful procedures in children with cancer. J Pediatr Hematol Oncol. 2011;33:119–27.PubMedCrossRef
8.
Zurück zum Zitat Scottish Intercollegiate Guidelines Network. Safe sedation of children undergoing diagnostic and therapeutic procedures. SIGN 58. 2004. Scottish Intercollegiate Guidelines Network. Safe sedation of children undergoing diagnostic and therapeutic procedures. SIGN 58. 2004.
9.
Zurück zum Zitat Hain RD, Campbell C. Invasive procedures carried out in conscious children: contrast between North American and European paediatric oncology centres. Arch Dis Child. 2001;85:12–5.PubMedCrossRef Hain RD, Campbell C. Invasive procedures carried out in conscious children: contrast between North American and European paediatric oncology centres. Arch Dis Child. 2001;85:12–5.PubMedCrossRef
10.
Zurück zum Zitat Barnes C, Downie P, Chalkiadis G, Camilleri S, Monagle P, Waters K. Sedation practices for Australian and New Zealand paediatric oncology patients. J Paediatr Child Health. 2002;38:170–2.PubMedCrossRef Barnes C, Downie P, Chalkiadis G, Camilleri S, Monagle P, Waters K. Sedation practices for Australian and New Zealand paediatric oncology patients. J Paediatr Child Health. 2002;38:170–2.PubMedCrossRef
11.
Zurück zum Zitat Yeh CH, Lin CF, Tsai JL, Lai YM, Ku HC. Determinants of parental decisions on 'drop out' from cancer treatment for childhood cancer patients. J Adv Nurs. 1999;30:193–9.PubMedCrossRef Yeh CH, Lin CF, Tsai JL, Lai YM, Ku HC. Determinants of parental decisions on 'drop out' from cancer treatment for childhood cancer patients. J Adv Nurs. 1999;30:193–9.PubMedCrossRef
12.
Zurück zum Zitat Sitaresmi MN, Mostert S, Schook RM, Sutaryo, Veerman AJ. Treatment refusal and abandonment in childhood acute lymphoblastic leukemia in Indonesia: an analysis of causes and consequences. Psychooncology. 2010;19:361–7.PubMedCrossRef Sitaresmi MN, Mostert S, Schook RM, Sutaryo, Veerman AJ. Treatment refusal and abandonment in childhood acute lymphoblastic leukemia in Indonesia: an analysis of causes and consequences. Psychooncology. 2010;19:361–7.PubMedCrossRef
13.
Zurück zum Zitat Oldenmenger WH, Sillevis Smitt PA, van Dooren S, Stoter G, van der Rijt CC. A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: a critical appraisal. Eur J Cancer. 2009;45:1370–80.PubMedCrossRef Oldenmenger WH, Sillevis Smitt PA, van Dooren S, Stoter G, van der Rijt CC. A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: a critical appraisal. Eur J Cancer. 2009;45:1370–80.PubMedCrossRef
15.
Zurück zum Zitat Koshy RC, Rhodes D, Devi S, Grossman SA. Cancer pain management in developing countries: a mosaic of complex issues resulting in inadequate analgesia. Support Care Cancer. 1998;6:430–7.PubMedCrossRef Koshy RC, Rhodes D, Devi S, Grossman SA. Cancer pain management in developing countries: a mosaic of complex issues resulting in inadequate analgesia. Support Care Cancer. 1998;6:430–7.PubMedCrossRef
16.
Zurück zum Zitat Funk LM, Weiser TG, Berry WR, et al. Global operating theatre distribution and pulse oximetry supply: an estimation from reported data. Lancet. 2010;376:1055–61.PubMedCrossRef Funk LM, Weiser TG, Berry WR, et al. Global operating theatre distribution and pulse oximetry supply: an estimation from reported data. Lancet. 2010;376:1055–61.PubMedCrossRef
Metadaten
Titel
A Survey of Procedural Sedation and Analgesia Practices in Pediatric Oncology Centers in India
verfasst von
Ramandeep Singh Arora
Ketan P. Kulkarni
Robert D. Alston
Publikationsdatum
01.12.2012
Verlag
Springer-Verlag
Erschienen in
Indian Journal of Pediatrics / Ausgabe 12/2012
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-012-0724-x

Weitere Artikel der Ausgabe 12/2012

Indian Journal of Pediatrics 12/2012 Zur Ausgabe

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

ADHS-Medikation erhöht das kardiovaskuläre Risiko

16.05.2024 Herzinsuffizienz Nachrichten

Erwachsene, die Medikamente gegen das Aufmerksamkeitsdefizit-Hyperaktivitätssyndrom einnehmen, laufen offenbar erhöhte Gefahr, an Herzschwäche zu erkranken oder einen Schlaganfall zu erleiden. Es scheint eine Dosis-Wirkungs-Beziehung zu bestehen.

Erstmanifestation eines Diabetes-Typ-1 bei Kindern: Ein Notfall!

16.05.2024 DDG-Jahrestagung 2024 Kongressbericht

Manifestiert sich ein Typ-1-Diabetes bei Kindern, ist das ein Notfall – ebenso wie eine diabetische Ketoazidose. Die Grundsäulen der Therapie bestehen aus Rehydratation, Insulin und Kaliumgabe. Insulin ist das Medikament der Wahl zur Behandlung der Ketoazidose.

Frühe Hypertonie erhöht späteres kardiovaskuläres Risiko

Wie wichtig es ist, pädiatrische Patienten auf Bluthochdruck zu screenen, zeigt eine kanadische Studie: Hypertone Druckwerte in Kindheit und Jugend steigern das Risiko für spätere kardiovaskuläre Komplikationen.

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.